Rhabdomyolysis classically presents with myalgia, generalized weakness, and darkened urine (myoglobinuria). Complications include acute kidney injury and crush syndrome, the systemic manifestation of traumatic rhabdomyolysis. [amboss.com]

If present it should be treated with fasciotomy. Fasciotomies should not be performed if the compartment syndrome has been present for > 24 hours. Open wounds should be treated with antibiotics, tetanus toxoid and debridement of necrotic tissue. [cancertherapyadvisor.com]

Pacer spikes are present, and demonstrate an inability to both capture and to sense intrinsic ventricular activity (arrows). [omicsonline.org]

In this article Pathophysiology Epidemiology Presentation Initial management Investigations Further management Complications Prognosis Prevention Crush Syndrome In this article Pathophysiology Epidemiology Presentation Initial management Investigations [patient.info]

(Figure 3) The clinical picture is presented here in the diagram below (Figure 4). You can see the hypotension, crushed limbs, acute renal failure, DIC, and compartment syndrome—the pulses may not be affected. [huffpost.com]

• Oliguria

  […] injury (prerenal) [4] Reperfusion syndrome → compartment syndrome Clinical features Rhabdomyolysis Classic triad Myalgia Generalized weakness Darkened urine (red to brown) Nonspecific symptoms: fever;, nausea, vomiting Complications Acute kidney injury: oliguria [amboss.com]

  The appearance, duration and gravity of oliguria and kidney damage are not related to the severity of muscle damage [ 6 ]. The muscles are grossly swollen, hard, cold, insensitive and necrotic. [ncbi.nlm.nih.gov]

  Dialysis and Hemofiltration Oliguria or anuria responsive to treatment, fluid therapy, volume overload, and a rising serum potassium (47 mEq/L) are indicators of the need for dialysis. [cancertherapyadvisor.com]

  There may be oliguria with profound hypovolaemic shock. Nausea, vomiting, confusion and agitation may occur as consequences of disturbed body chemistry; urea, creatinine, uric acid, potassium, phosphate and creatine kinase are elevated. [patient.info]

• Kidney Failure

  [citation needed] The progressive acute kidney failure is because of acute tubular necrosis. [en.wikipedia.org]

  Depending on medical direction, the use of bicarbonate and mannitol to prevent kidney failure has been called into question. [ems1.com]

Note: - Confined space and a MVI situation may compromise treatment. [jointemsprotocols.com]

This article will cover four areas: basic pathophysiology, patient assessment, management and treatment and ECG changes. 1. [ems1.com]

The syndrome of rhabdomyolysis: Complications and treatment. Eur J Intern Med. 2008; 19 (8): p.568-574. doi: 10.1016/j.ejim.2007.06.037. | Open in Read by QxMD [amboss.com]

treatment option that can undo the effects and damage from Rhabdomyolysis because it is a necrosis.[10] However, the rate of the pathology that can lead to more complications can be decreased by acting early and consistently.[11] Overall treatment depends [en.wikipedia.org]

Treatment In scenario of crush injuries, we are dealing with rescue, resuscitation, recognition of the syndrome, treatment and rehabilitation. [ncbi.nlm.nih.gov]

If levels continue to elevate, consider ongoing muscle injury or compartment syndrome.[11] Prognosis Adequate fluid support improves prognosis.[12] The mortality rate for crush syndrome following the earthquake in northern Turkey in 1999 was 15.2%.[13 [patient.info]

Definition Etiology Causes of rhabdomyolysis Traumatic Crush injury Direct injury Nontraumatic Seizures Overexertion (e.g., ultramarathon) Intoxication (e.g., cocaine, heroin, alcohol, carbon monoxide, phencyclidine) Skeletal muscle ischemia [2] Infection [amboss.com]

The etiology of her symptoms was presumed to be secondary to a non-functional device due to the non-functional lead. [omicsonline.org]

In this article Pathophysiology Epidemiology Presentation Initial management Investigations Further management Complications Prognosis Prevention Crush Syndrome In this article Pathophysiology Epidemiology Presentation Initial management Investigations [patient.info]

This article reviews the epidemiology, pathophysiology, diagnosis, and early management of crush syndrome. [nursingcenter.com]

In this article Pathophysiology Epidemiology Presentation Initial management Investigations Further management Complications Prognosis Prevention Crush Syndrome In this article Pathophysiology Epidemiology Presentation Initial management Investigations [patient.info]

Nontraumatic Seizures Overexertion (e.g., ultramarathon) Intoxication (e.g., cocaine, heroin, alcohol, carbon monoxide, phencyclidine) Skeletal muscle ischemia [2] Infection Adverse drug reactions (e.g., neuroleptics, statins) Malignant hyperthermia Pathophysiology [amboss.com]

This article will cover four areas: basic pathophysiology, patient assessment, management and treatment and ECG changes. 1. [ems1.com]

Pathophysiology The pathophysiology begins with muscle injury and muscle cell death. Immediate cell disruption. Direct pressure on muscle cells: The direct pressure causes muscle cells to become ischemic. [cancertherapyadvisor.com]

This article reviews the epidemiology, pathophysiology, diagnosis, and early management of crush syndrome. [nursingcenter.com]

It also prevents neutrophil adhesion and prevents secondary injury. It is directly bactericidal to anaerobic organisms. [cancertherapyadvisor.com]

Prevention In any major disaster, adequate triage must carried out to identify those in need of urgent attention. [patient.info]

Use intravenous sodium bicarbonate to keep the urine pH at 6.5 or greater, to prevent myoglobin and uric acid deposition in kidneys. [en.wikipedia.org]

It is also important to keep the patient warm with warm fluids and heating blankets to prevent hypothermia. [emsworld.com]

Although difficult to achieve, alkalinization of the urine may be beneficial in preventing renal failure and can be started with initial volume resuscitation. [nursingcenter.com]