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Crystalluria


Presentation

  • Abstract A case of severe ethylene glycol poisoning is presented, characterized by protracted delirium, coma, and delayed adult respiratory distress syndrome.[ncbi.nlm.nih.gov]
  • After a presentation of the three steps (pre-analytical, analytical and post-analytical) performed in the laboratory, the authors present some insights in order to mitigate the lack of the urinary IQC.[ncbi.nlm.nih.gov]
  • CONCLUSIONS: The studied series presents a non high frequency of crystalluria, which increases with the age. The factor sex has weakly increased the frequency of crystalluria in the man compared to the woman.[ncbi.nlm.nih.gov]
  • The type of crystals present in urine as well as their size, number by cubic millimeter and state of aggregation were determined.[ncbi.nlm.nih.gov]
  • Abstract A case of urinary crystalluria occurring in a patient during treatment with flucytosine (5-fluorocytosine) is presented.[ncbi.nlm.nih.gov]
Intravenous Administration
  • There were no differences in ofloxacin recovery after oral or intravenous administration, confirming that absolute bioavailability of the oral form is excellent.[ncbi.nlm.nih.gov]
  • Ciprofloxacin can cause crystalluria in alkaline urine (especially at pH 7.3), both in experimental animals and in healthy human volunteers after oral or intravenous administration [ 1–3 ].[academic.oup.com]
El Salvador
  • Consistent with this hypothesis, we present pilot data documenting the common presence of urate crystals in the urine of sugarcane workers from El Salvador.[ncbi.nlm.nih.gov]
Respiratory Distress
  • Abstract A case of severe ethylene glycol poisoning is presented, characterized by protracted delirium, coma, and delayed adult respiratory distress syndrome.[ncbi.nlm.nih.gov]
  • AB - A case of severe ethylene glycol poisoning is presented, characterized by protracted delirium, coma, and delayed adult respiratory distress syndrome.[scholars.northwestern.edu]
Suggestibility
  • The primidone levels suggest that primidone is rapidly cleared into urine.[ncbi.nlm.nih.gov]
  • It is suggested that entrapment sites within the urinary tract have a selective specificity for these crystals while urinary salts pass through unhindered.[ncbi.nlm.nih.gov]
  • Our data suggest urine supersaturation with respect to calcium oxalate was found in both renal stone patients and normal subjects but more frequently in the former and also suggests more deficiency or lack of inhibitors for oxalate crystal nucleation[ncbi.nlm.nih.gov]
  • Both the calculated drug clearances and the remarkable improvement in the patient's clinical condition suggest that haemoperfusion was very effective.[ncbi.nlm.nih.gov]
  • It is suggested that acyclovir crystalluria might be an early sign of acyclovir crystal nephropathy.[ncbi.nlm.nih.gov]
Altered Mental Status
  • Ethylene glycol intoxication should be considered in the patient who presents with an altered mental status, unexplained metabolic acidosis, and elevated anion and osmolal gaps with or without crystalluria.[ncbi.nlm.nih.gov]
  • Abstract We report a 20-year-old woman who developed altered mental status, massive crystalluria, and acute renal failure following an intentional overdose of felbamate and sodium valproate.[ncbi.nlm.nih.gov]
Dysuria
  • This crystalluria may be associated with dysuria and urinary frequency, with flank or back pain associated with intrarenal sludging, and with the classic syndrome of renal colic.[annals.org]
Cloudy Urine
  • Crystalluria Struvite crystals found in a urinalysis Crystalluria refers to cloudy urine when the cause of cloudiness is due to crystals found in the urine when performing a urine test.[en.wikipedia.org]
  • urine Crude urine Crystalluria Deposit in urine Diabetic urine Discolored urine Drug, medicament, or biological substance in urine above reference range Dyspeptic urine Elevated urine sodium Elevated urine sodium measurement Elevated urine uric acid[icd9data.com]

Treatment

  • CONCLUSIONS: Treatment with indinavir can result in crystalluria with potentially severe obstruction.[ncbi.nlm.nih.gov]
  • Abstract A case of urinary crystalluria occurring in a patient during treatment with flucytosine (5-fluorocytosine) is presented.[ncbi.nlm.nih.gov]
  • Abstract The authors report the case of a 45-year-old woman admitted for pneumonia who presented anuric acute renal failure after 12 days of intravenous amoxycillin-clavulanate treatment.[ncbi.nlm.nih.gov]
  • Awareness of its existence may lead to prevention and early conservative treatment.[ncbi.nlm.nih.gov]
  • Accordingly, the study of crystalluria in patients with urolithiasis seems to help in the proper evaluation and, maybe, treatment of the disease.[ncbi.nlm.nih.gov]

Prognosis

  • Analysis of blood and urine for primidone and phenobarbital and urine for crystals is of value in establishing diagnosis and prognosis in cases of suspected primidone overdosage.[ncbi.nlm.nih.gov]
  • Abstract The qualitative and quantitative analyses of crystalluria have clinical significance in the diagnosis and prognosis of urolithiasis.[ncbi.nlm.nih.gov]
  • Abstract The significance of crystalluria in the diagnosis and prognosis of urolithiasis remains a controversial subject in the current urological literature.[ncbi.nlm.nih.gov]
  • Despite the poor visual prognosis of this eye, the symptomatic nature of this lesion and the intensity of the inflammatory response prompted treatment.[bjo.bmj.com]
  • Prognosis The prognosis is uncertain in the severe form of the disease. Severe gout can lead to renal impairment, if not properly treated. The documents contained in this web site are presented for information purposes only.[orpha.net]

Etiology

  • Other studies are necessary to be able to understand the etiology of a such difference, in the chemical nature of the crystalluria, between the two sexes.[ncbi.nlm.nih.gov]
  • In conclusion, the proposed morpho-constitutional method of urinary stone analysis, which moreover is rapid and low cost, provides clinically relevant orientations for targeted etiologic evaluation. Copyright 2016 IJS Publishing Group Ltd.[ncbi.nlm.nih.gov]
  • KEYWORDS: Central America; Mesoamerican nephropathy (MeN); chronic kidney disease (CKD); dehydration; etiology; heat stress nephropathy; hyperuricemia; hypothesis; physical exertion; rhabdomyolysis; sugarcane workers; tubular injury; uric acid crystalluria[ncbi.nlm.nih.gov]
  • Daudon M, Bader CA, Jungers P: Urinary calculi: Review of classification methods and correlations with etiology. Scan Microsc 1993;7:1081–1106. Simmonds HA: 2,8-Dihydroxyadenine lithiasis. Clin Chim Acta 1986;160:103–108.[karger.com]
  • Etiology The disease is due to overactivity of ribose-phosphate pyrophosphokinase 1 (PRS-I), an enzyme that catalyzes the synthesis of PRPP, a cofactor involved in the synthesis of purine and pyrimidine nucleotides.[orpha.net]

Epidemiology

  • […] para el Desarrollo y la Salud Agropecuaria, San Salvador, El Salvador. 8 Research Center on Health, Work and Environment (CISTA), National Autonomous University of Nicaragua at León (UNAN-León), León, Nicaragua; Department of Non-communicable Disease Epidemiology[ncbi.nlm.nih.gov]
  • Database of over 1 MILLION veterinary samples Epidemiologic data identifying risk factors for urolithiasis Recommendations on urolith dissolution and prevention Consultation services Clinical Studies Lectures and seminars around the world to disseminate[cvm.umn.edu]
  • Summary Epidemiology PRPP synthetase superactivity is a rare disorder with less than 30 families described in the literature to date. Clinical description PRPP synthetase superactivity affects mainly males.[orpha.net]
  • Drug-induced renal calculi: epidemiology, prevention and management. Drugs 2004;64:245–75. Google Scholar 23. Verdesca S, Fogazzi GB, Garigali G, Messa P, Daudon M.[degruyter.com]
Sex distribution
Age distribution

Pathophysiology

  • Singer A, Das S (1989) Cystinuria: a review of the pathophysiology and management. J Urol 142: 669 PubMed Google Scholar 28. Sloand JA, Izzo JLJr (1987) Captopril reduces urinary cystine excretion in cystinuria.[doi.org]
  • Pathophysiology-based treatment of idiopathic calcium kidney stones. Clin J Am Soc Nephrol. 2011; 6 :2083–2092. [ PMC free article ] [ PubMed ] 5. Evan AP, Lingeman JE, Worcester EM, Sommer AJ, Phillips CL, Williams JC, Coe FL.[ncbi.nlm.nih.gov]

Prevention

  • In all types of nephrolithiasis, serial crystalluria determination appears as a simple, cheap and reliable method to evaluate the risk of stone formation and assess the effectiveness of preventive measures.[ncbi.nlm.nih.gov]
  • Urinalysis also should be performed regularly for appropriate monitoring and prevention.[ncbi.nlm.nih.gov]
  • Awareness of its existence may lead to prevention and early conservative treatment.[ncbi.nlm.nih.gov]
  • It is proposed that early ethanol therapy may prevent the formation of ethylene glycol metabolites to the extent that calcium oxalate crystalluria is not seen.[ncbi.nlm.nih.gov]
  • We speculated that crystalluria may be predictive of this nephrolithogenic tendency and thus investigated the effect of an intensive therapeutic strategy to prevent crystal formation in 13 children at our hospital.[ncbi.nlm.nih.gov]

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