Edit concept Create issue ticket

Crystalluria


Presentation

  • Early empiric ethanol therapy and consideration of dialysis are recommended for those patients with such a presentation without evidence of abnormal levels of ketones, lactate, salicylate, or ethanol.[ncbi.nlm.nih.gov]
  • After a presentation of the three steps (pre-analytical, analytical and post-analytical) performed in the laboratory, the authors present some insights in order to mitigate the lack of the urinary IQC.[ncbi.nlm.nih.gov]
  • The studied series presents a non high frequency of crystalluria, which increases with the age. The factor sex has weakly increased the frequency of crystalluria in the man compared to the woman.[ncbi.nlm.nih.gov]
  • The type of crystals present in urine as well as their size, number by cubic millimeter and state of aggregation were determined.[ncbi.nlm.nih.gov]
  • A case of urinary crystalluria occurring in a patient during treatment with flucytosine (5-fluorocytosine) is presented.[ncbi.nlm.nih.gov]
Suggestibility
  • The primidone levels suggest that primidone is rapidly cleared into urine.[ncbi.nlm.nih.gov]
  • It is suggested that entrapment sites within the urinary tract have a selective specificity for these crystals while urinary salts pass through unhindered.[ncbi.nlm.nih.gov]
  • Our data suggest urine supersaturation with respect to calcium oxalate was found in both renal stone patients and normal subjects but more frequently in the former and also suggests more deficiency or lack of inhibitors for oxalate crystal nucleation[ncbi.nlm.nih.gov]
  • Both the calculated drug clearances and the remarkable improvement in the patient's clinical condition suggest that haemoperfusion was very effective.[ncbi.nlm.nih.gov]
  • It is suggested that acyclovir crystalluria might be an early sign of acyclovir crystal nephropathy.[ncbi.nlm.nih.gov]
Dysuria
  • This crystalluria may be associated with dysuria and urinary frequency, with flank or back pain associated with intrarenal sludging, and with the classic syndrome of renal colic.[annals.org]
Cloudy Urine
  • Crystalluria Struvite crystals found in a urinalysis Classification and external resources ICD - 10 R82.9 ICD - 9-CM 791.9 [ edit on Wikidata ] Crystalluria refers to cloudy urine when the cause of cloudiness is due to crystals found in the urine when[en.wikipedia.org]

Treatment

  • Treatment with indinavir can result in crystalluria with potentially severe obstruction.[ncbi.nlm.nih.gov]
  • A case of urinary crystalluria occurring in a patient during treatment with flucytosine (5-fluorocytosine) is presented.[ncbi.nlm.nih.gov]
  • The authors report the case of a 45-year-old woman admitted for pneumonia who presented anuric acute renal failure after 12 days of intravenous amoxycillin-clavulanate treatment.[ncbi.nlm.nih.gov]
  • Awareness of its existence may lead to prevention and early conservative treatment.[ncbi.nlm.nih.gov]
  • The findings indicate the importance of adequate hydration, urinalysis, measurement of pH and liver enzyme levels, prior to treatment with ciprofloxacin.[ncbi.nlm.nih.gov]

Prognosis

  • Analysis of blood and urine for primidone and phenobarbital and urine for crystals is of value in establishing diagnosis and prognosis in cases of suspected primidone overdosage.[ncbi.nlm.nih.gov]
  • The qualitative and quantitative analyses of crystalluria have clinical significance in the diagnosis and prognosis of urolithiasis.[ncbi.nlm.nih.gov]
  • The significance of crystalluria in the diagnosis and prognosis of urolithiasis remains a controversial subject in the current urological literature.[ncbi.nlm.nih.gov]
  • Despite the poor visual prognosis of this eye, the symptomatic nature of this lesion and the intensity of the inflammatory response prompted treatment.[bjo.bmj.com]
  • Prognosis The prognosis is uncertain in the severe form of the disease. Severe gout can lead to renal impairment, if not properly treated. The documents contained in this web site are presented for information purposes only.[orpha.net]

Etiology

  • Other studies are necessary to be able to understand the etiology of a such difference, in the chemical nature of the crystalluria, between the two sexes.[ncbi.nlm.nih.gov]
  • In conclusion, the proposed morpho-constitutional method of urinary stone analysis, which moreover is rapid and low cost, provides clinically relevant orientations for targeted etiologic evaluation.[ncbi.nlm.nih.gov]
  • Daudon M, Bader CA, Jungers P: Urinary calculi: Review of classification methods and correlations with etiology. Scan Microsc 1993;7:1081–1106. Simmonds HA: 2,8-Dihydroxyadenine lithiasis. Clin Chim Acta 1986;160:103–108.[karger.com]
  • Etiology The disease is due to overactivity of ribose-phosphate pyrophosphokinase 1 (PRS-I), an enzyme that catalyzes the synthesis of PRPP, a cofactor involved in the synthesis of purine and pyrimidine nucleotides.[orpha.net]
  • Impact of socioeconomic status in etiology and management of urinary stone disease. Urol Int 2003;70:255-61. [Figure 1] [Table 1] , [Table 2] , [Table 3] , [Table 4] , [Table 5][nigeriamedj.com]

Epidemiology

  • Summary Epidemiology PRPP synthetase superactivity is a rare disorder with less than 30 families described in the literature to date. Clinical description PRPP synthetase superactivity affects mainly males.[orpha.net]
  • Drug-induced renal calculi: epidemiology, prevention and management. Drugs 2004;64:245–75. Google Scholar 23. Verdesca S, Fogazzi GB, Garigali G, Messa P, Daudon M.[degruyter.com]
Sex distribution
Age distribution

Pathophysiology

  • Pathophysiology-based treatment of idiopathic calcium kidney stones. Clin J Am Soc Nephrol. 2011; 6 :2083–2092. [ PMC free article ] [ PubMed ] 5. Evan AP, Lingeman JE, Worcester EM, Sommer AJ, Phillips CL, Williams JC, Coe FL.[ncbi.nlm.nih.gov]

Prevention

  • In all types of nephrolithiasis, serial crystalluria determination appears as a simple, cheap and reliable method to evaluate the risk of stone formation and assess the effectiveness of preventive measures.[ncbi.nlm.nih.gov]
  • Urinalysis also should be performed regularly for appropriate monitoring and prevention.[ncbi.nlm.nih.gov]
  • Awareness of its existence may lead to prevention and early conservative treatment.[ncbi.nlm.nih.gov]
  • It is proposed that early ethanol therapy may prevent the formation of ethylene glycol metabolites to the extent that calcium oxalate crystalluria is not seen.[ncbi.nlm.nih.gov]
  • We speculated that crystalluria may be predictive of this nephrolithogenic tendency and thus investigated the effect of an intensive therapeutic strategy to prevent crystal formation in 13 children at our hospital.[ncbi.nlm.nih.gov]

Ask Question

5000 Characters left Format the text using: # Heading, **bold**, _italic_. HTML code is not allowed.
By publishing this question you agree to the TOS and Privacy policy.
• Use a precise title for your question.
• Ask a specific question and provide age, sex, symptoms, type and duration of treatment.
• Respect your own and other people's privacy, never post full names or contact information.
• Inappropriate questions will be deleted.
• In urgent cases contact a physician, visit a hospital or call an emergency service!