Presentation
The book covers the entire spectrum of HIV-associated cutaneous diseases, and emphasizes how they present in immunocompromised patients. [books.google.de]
Morphologically, the patients may present with abscesses, ulcers, draining sinus tracts, cellulitis or tender erythematous nodules. [ijdvl.com]
Most often tuberculosis is an airborne transmissible disease with skin manifestations presenting as a result of haematogenous spread or direct extension from latent or active foci of infection. [pcds.org.uk]
Fibrosis and granulation tissue are often present, and may be florid. Acid-fast stains may show the organisms. The highest-yield location to them out is within microabscesses or vacuoles. [dermpedia.org]
Abstract Patients with systemic lupus erythematosus (SLE) who present with skin disease pose the clinician with diagnostic challenges. [academic.oup.com]
Entire Body System
- Weakness
At other times, they can cause lung symptoms similar to tuberculosis: Cough Weight loss Coughing up blood or mucus Weakness or fatigue Fever and chills Night sweats Lack of appetite and weight loss Medicines can treat these infections, but often more [icdlist.com]
In people with weak immune systems, the infection can erupt into widespread disease. This infection is rare in the United States, but people with chronic lung disease are especially susceptible. [humanillnesses.com]
[…] is important because these bacteria do not respond to the first-line antikoch's treatment, and even may not respond well to the second-line antimycobacterial treatment. [1] A 48-year female presented with complaints of generalized edema, generalized weakness [e-ijd.org]
However, elderly adults and individuals with poor/weak immunity, are more likely to develop such infections Males and females are equally susceptible to developing the infection. [dovemed.com]
Patients can report systemic and constitutional symptoms that include productive cough/purulent sputum, hemoptysis, weight loss, weakness, fever, and night sweats. [dermaamin.com]
Respiratoric
- Chronic Cough
It can be caused by many NTM species which depends on region, but most frequently MAC and M. kansasii. [14] Clinical symptoms vary in scope and intensity but commonly include chronic cough, often with purulent sputum. Hemoptysis may also be present. [en.wikipedia.org]
Skin
- Skin Lesion
Twelve months later, the patient’s skin lesions have healed and the skin is intact with keloid formation. [nzma.org.nz]
It also can involve the lymph nodes and cause skin lesions. In people with weak immune systems, the infection can erupt into widespread disease. [humanillnesses.com]
Surgical removal of infected lymph nodes and aggressive debridement of infected skin lesions is sometimes necessary. In severe cases, skin grafts may be necessary to repair the surgical wound. [dermnetnz.org]
lesions; has nodules which may be verrucous or become crusted ulcers; also papulopustules, cellulitis or spreading infection resembling sporotrichosis Rarely, squamous cell carcinoma may arise in a chronic Buruli ulcer Clinical images Images hosted on [pathologyoutlines.com]
- Erythema
", keywords = "erythema induratum, mycobacterium infections, atypical, mycobacterium tuberculosis", author = "S. [moh-it.pure.elsevier.com]
- Prominence of neutrophils: Impetigo, Granuloma Inguinale, erysipelas, erythema nodosum leprosum, blastomycosis-like pyoderma, chancroid, mycetoma, actinomycosis, phaeohyphomycosis, mucormycosis. - Presence of histiocytes and plasma cells: Rhinoscleroma [histopathology-india.net]
|| doi: 10.5694/j.1326-5377.2009.tb02396.x Published online: 2 March 2009 Clinical record A: Tattooed area of right arm, showing erythema, papules and nodules. [mja.com.au]
Tuberculides [ 9 ] Skin reactions to systemic tuberculosis - eg, erythema nodosum, erythema induratum (Bazin's disease). Leprosy (Hansen's disease) [ 10 ] See separate Leprosy article. [patient.info]
Erythema induratum of Bazin and Whitfield) Clinical findings Cutaneous mycobacterial infection, most commonly caused by Mycobacterium tuberculosis, is one of the great mimickers and has many presentations: 1) Any persistent, painless, and recalcitrant [pcds.org.uk]
- Skin Ulcer
NTM infections can occur in well children and include lymphadenitis, skin ulcers, and rarely otomastoiditis and posttraumatic soft-tissue or bone infections. [pedsinreview.aappublications.org]
A 43-year-old Samoan man presented with a 3-month history of progressively worsening skin ulceration of his right leg and arm. This was on a background of an 8-year history of a chronic, unexplained right lower leg skin lesion. [nzma.org.nz]
- Skin Plaque
Following the injury, a progressively expanding, pruritic, erythematous, keloid skin plaque with pustules gradually developed to involve the right lower limb. [nzma.org.nz]
- Chancre
Download Figure: 1 Tuberculous chancre Download Figure: 2 Tuberculous chancre following a road traffic accident Download Figure: 3 Primary tuberculosis following acupuncture All cases were caused by the same practitioner (in Korea) Download Figure: 4 [pcds.org.uk]
Treatment
Thirty-two patients received treatment and 31 responded. Twenty-six were treated with oral tetracycline group of antibiotics (minocycline, doxycycline, tetracycline). The duration of treatment ranged from 8 to 54 weeks (mean, 24 weeks). [hkmj.org]
The latest treatments are described, including Highly Active Antiretroviral Therapy (HAART). [books.google.de]
The lack of consensus on treatment is a reflection of the paucity of data derived from clinical trials. [academic.oup.com]
Management Effective treatment depends on precise diagnosis and identification of the underlying organism. Treatment will also be governed by results of culture and sensitivity. [patient.info]
Usually treatment consists of a combination of drugs. [dermnetnz.org]
Prognosis
Prognosis The prognosis is good with proper medical and surgical treatment. [patient.info]
Pak Med Assoc 54:379–382 CAS Google Scholar Ollé Goig JE, Sandy R (2003) Prognosis of mono-and polydrug resistant pulmonary tubercolosis in the city of Santa Cruz, Bolivia. [link.springer.com]
Thus, diagnosis of atypical mycobacteria is important now days, otherwise the infection could result in adverse prognosis. [Figure 1], [Figure 2], [Figure 3] [e-ijd.org]
Gummas form from non‐tender nodules that occur anywhere on the body and can become fluctuant and break down to form local sinuses; they have a poor prognosis in malnourished individuals [ 12 ]. [academic.oup.com]
Etiology
(Etiology) Atypical Mycobacterial Infections are caused by any species of non-tuberculous mycobacteria. Up to 13 distinct species of atypical mycobacteria are known to cause human infection. [dovemed.com]
Mycobacterium avium-intracellulare is the most common etiology of systemic disease in humans. Other types of mycobacteria are discussed in different Medscape Drugs and Diseases articles (eg, Mycobacterium Fortuitum, Mycobacterium gordonae ). [emedicine.medscape.com]
Mycobacterium avium-intracellulare is the most common etiology of systemic disease in humans. Other types of mycobacteria are discussed in different eMedicine articles (eg, Mycobacterium Fortuitum, Mycobacterium gordonae). [dermaamin.com]
[…] to mycobacterial infection was reported.[ 2 ] The affected patients were maternally related members of the family revealed to have defective IL-12 production, which is necessary to defend against mycobacteria.[ 2 ] Later that same year, the genetic etiology [mjhid.org]
Epidemiology
Epidemiological data, clinical features, histology, microbiological investigation, and treatment response. RESULT. [hkmj.org]
In a concise and user-friendly format, it offers authoritative coverage of epidemiology, diagnosis, differential diagnosis, pathology, laboratory tests, management, and prevention for both common and rare conditions. [books.google.de]
Delineate distinguishing epidemiological and clinical features of nontuberculous mycobacterial skin infections. List the general principles of how nontuberculous mycobacteria are identified in the laboratory. [pedsinreview.aappublications.org]
Horsburgh CR Jr. (1996) Epidemiology of disease caused by nontuberculous mycobacteria. Semin Respir Infect 11(4):244–251 PubMed Google Scholar 20. [link.springer.com]
Definition / general Skin disorders (ulcerations, abscesses, rheumatoid-like nodules, histiocytic reactions, panniculitis), most commonly due to M. kansasii, M. marinum, M. ulcerans Epidemiology Nontuberculous mycobacteria are nonpathogenetic; they inhabit [pathologyoutlines.com]
Pathophysiology
In conclusion, there are some clues about an association of skin infections with IgA-deficiency, although no clear pathophysiological link may be provided [ 11 – 13 ]. [bmcdermatol.biomedcentral.com]
Mycobacterium peregrinum can result in skin infections. [2] Pathophysiology Infections with atypical mycobacteria usually occur in immunocompromised hosts due to host immunity and resistance factors. [emedicine.medscape.com]
Pathophysiology Infections with atypical mycobacteria usually occur in immunocompromised hosts due to host immunity and resistance factors. Pulmonary infections can occur in patients with impaired ventilation systems. [dermaamin.com]
Prevention
(November 6, 2017) Centers for Disease Control and Prevention. CDC Features: Pneumonia can be prevented—vaccines can help. Available online at https://www.cdc.gov/Features/Pneumonia/. Accessed on September 8, 2018. [labtestsonline.it]
Seite 290 - Antibiotic prophylaxis for the prevention of bacterial infections in cirrhotic patients with gastrointestinal bleeding: A meta-analysis. Hepatology 1999; 29: 1655-61 6. [books.google.de]
Can People Prevent Atypical Mycobacterial Infections? Because mycobacteria are common in the environment, these infections are difficult to prevent, especially in people with weakened immune systems. [humanillnesses.com]
Specific prevention options for Atypical Mycobacterial Infections depend on the infecting species type. [dovemed.com]