Collections of epithelioid macrophages were present in both cases and were reminiscent of epithelioid granulomas. [ncbi.nlm.nih.gov]

A 62-year-old male presented with multiple asymptomatic swellings over the posterior aspect of the left ear of 1-year duration. [cdriadvlkn.org]

• Inflammation

  On occasion, drug-related eruptions may show more dermal mixed inflammation, including lymphocytes, conspicuous histiocytes, and scattered enlarged lymphoid cells ( C and D, H&E). [academic.oup.com]

  […] induced by gold acupuncture Kim, K; Lee, M; Choi, J Pseudolymphomatous reactions to tattoos Blumental, G; Okun, MR; Ponitch, A Pseudo T-cell lymphoma due to scabies in a patient with Hodgkin’s disease Walton, S; Bottomley, WW; Wyatt, EH; Bury, HP From inflammation [deepdyve.com]

  […] antibody-forming cell, 024136, 細胞, ｻｲﾎﾞｳ, cell, 011180, リンパ球, ﾘﾝﾊﾟｷｭｳ, lymphocyte, 012685, 白血球, ﾊｯｹｯｷｭｳ, leucocyte, 005701, 血球, ｹｯｷｭｳ, blood corpuscle, 010942, 血液成分, ｹﾂｴｷｾｲﾌﾞﾝ, blood component, 039516, 成分, ｾｲﾌﾞﾝ, component, 046068, 炎症, ｴﾝｼｮｳ(ﾋﾞｮｳｷ), inflammation [togodb.dbcls.jp]

  She also had a history of bursitis – more inflammation. Around the time her skin started acting up, she was also diagnosed with myotonic muscular dystrophy (MMD). [commonsensehome.com]

  Any surgery is associated with the risk of a relapse of inflammation and should be postponed until inflammation is controlled by systemic therapy. [journals.lww.com]

• Pseudotumor

  Am J Surg Pathol 34:271–278 CrossRef PubMed Google Scholar Aguirre-Garcia J (2004) Inflammatory pseudotumor of the liver. [link.springer.com]

  @article{Torbenson2020RegenerativeHP, title={Regenerative Hepatic Pseudotumor: A New Pseudotumor of the Liver.}, author={Michael S. Torbenson and Saba Yasir and Robert A Anders and Cynthia D. [semanticscholar.org]

  B-cell lymphoma (CBCL) mimickers Cutaneous lymphoid hyperplasia (CLH, lymphocytoma cutis) Borrelia-associated pseudolymphoma Drug-induced pseudo-CBCL Tattoo associated pseudolymphoma Vaccination associated pseudolymphoma Inflammatory morphea Inflammatory pseudotumor [dermatologyadvisor.com]

  They can be seen in some lymphomas (e.g., marginal zone lymphoma), Kimura disease, angiolymphoid hyperplasia with eosinophilia, Castleman disease, inflammatory pseudotumor of the skin, and morphea and as part of the host response to tumors such as basal [plasticsurgerykey.com]

• Epilepsy

  NYTOJN SENSITIVITY A N D HODGKIN'S DlSEASE Clinico-pathologic conference Lymphoma or drug reaction occurring during hydantoin therdpy for epilepsy, Amer. J Med 3% 286 flnowN. J. [docksci.com]

• Overeating

  We report a case of cutaneous pseudolymphoma induced by local application of 4% hydroquinone cream to melasma over the cheeks. [ncbi.nlm.nih.gov]

  The plaque progressed over the next 4 days after presentation; however, it gradually regressed spontaneously over the next 5 days leaving behind hyperpigmentation. [mjmsr.net]

  Figure 1: (a) Clinical picture showing multiple nodules over the left retroauricular area. [cdriadvlkn.org]

  Some may recur over time. The diagnosis of pseudolymphoma is made by both a combination of the clinical features and careful histological analysis. Often the diagnosis can be confirmed only by observing the behaviour of the condition over time. [dermnetnz.org]

• Fracture

  When tumor invades bones can lead to pain or fracture of bones, and if in nasopharynx may develop symptoms like nose obstruction, running nose, nasal bleeding, which are similar to the ones of nasopharyngeal cancer. 4、Lymphoma is a general disease, except [asiancancer.com]

  未熟奇形腫：immature teratoma 皮様嚢胞腫：dermoid cyst ◎卵巣甲状腺腫：struma ovarii ◎カルチノイド腫瘍：carcinoid tumor 線維腫：fibroma 腺線維腫：adenofibroma ◎Krukenberg腫瘍 運動器 1）骨 急性化膿性骨髄炎：acute suppurative osteomyelitis 慢性骨髄炎：chronic osteomyelitis 結核性骨髄炎：tuberculous osteomyelitis ◎骨折：bone fracture [medical-e.net]

• Dermatitis

  Lymphomatoid contact dermatitis was described originally in four patients with persistent allergic contact dermatitis proven by patch testing Responsible agents include gold, nickel and paraphenylenediamine. [slideshare.net]

  […] mycosis fungoides’) Lichenoid keratosis, (‘lymphomatoid’) Lichenoid pigmented purpuric dermatitis Lichen sclerosus. [dermnetnz.org]

  In our case, epicutaneous patch tests were strongly positive for a series of allergens contained in the ophthalmological preparations used; therefore, they were suggestive that the patient had CPL, lymphomatoid contact dermatitis type. [ncbi.nlm.nih.gov]

• Papule

  We report a patient with a sodium valproate-induced cutaneous pseudolymphoma, presenting with an erythematous papule, histologically mimicking a non-epidermotropic T-cell lymphoma. [ncbi.nlm.nih.gov]

  […] or widespread erythematous papules, plaques and nodules, but occasionally, lesions may be generalized. [slideshare.net]

  Papules showed predominant hyperpigmentation in three patients. [ijdvl.com]

  Fever Lymphadenopathy Erythematous eruptions Widespread erythematous papules,plaques or nodules 12. [de.slideshare.net]

• Keratosis

  LYMPHOMATOID KERATOSIS Lymphomatoid keratosis: an epidermotropic type of cutaneous lymphoid hyperplasia: clinicopathological, immunohistochemical, and molecular biological study of 6 cases. Arai E, Shimizu M, Tsuchida T, Izaki S, Ogawa F, Hirose T. [thedoctorsdoctor.com]

  […] pilaris (Medical Encyclopedia) Lichen planus (Medical Encyclopedia) Milia (Medical Encyclopedia) Sebaceous cyst (Medical Encyclopedia) Seborrheic keratosis (Medical Encyclopedia) Skin lesion removal (Medical Encyclopedia) Skin lesion removal-aftercare [icdlist.com]

  […] pseudolymphomas Conditions that can simulate mycosis fungoides/Sézary syndrome include: Actinic reticuloid Lymphomatoid contact dermatitis Lymphomatoid drug reaction, T-cell type Solitary T-cell pseudolymphoma (‘unilesional mycosis fungoides’) Lichenoid keratosis [dermnetnz.org]

  (lichen planus-like keratosis) exist. 10. [slideshare.net]

• Hyperkeratosis

  Hyperkeratosis with parakeratosis, acanthosis, spongiosis and exocytosis with Pautrier-like micro-abscesses in the epidermis. There is moderate mixed inflammatory infiltration in the dermis (H&E × 10). Fig. 3. [medicaljournals.se]

  There is no follicular hyperkeratosis as seen in discoid lupus erythematosus, which may be simulated. [drdigambiro.blogspot.com]

  Occasionally, the epidermis may exhibit variable degrees of hyperkeratosis, parakeratosis, acanthosis, dyskeratosis, spongiosis, and basal vacuolar degeneration. Arthropod-induced reactions may show prominent epidermal hyperplasia or ulceration. [plasticsurgerykey.com]

  Close examination, however, revealed additional histologic features that supported an inflammatory etiology, including rare necrotic keratinocytes, associated spongiosis, orthokeratosis/hyperkeratosis, parakeratosis with intracorneal neutrophils, and [academic.oup.com]

  […] dermatitis can be distinguished from early patch-stage MF by a perivascular (rather than band-like) SDI which includes neutrophils and surrounds tortuous and dilated papillary dermal blood vessels, coupled with regular epidermal hyperplasia, hypogranulosis, hyperkeratosis [e-ijd.org]

• Eczema

  They can look like more common skin conditions such as dermatitis, eczema or psoriasis. Figure: Patches of mycosis fungoides showing areas of dry, red skin The patches tend to be dry, sometimes scaly and may be itchy. [lymphomas.org.uk]

  Relapsing polychondritis 673 211 Rhinophyma 677 212 Rocky Mountain spotted fever and other rickettsial infections 679 213 Rosacea 684 214 Sarcoidosis 692 215 Scabies 697 216 Scleredema 700 217 Scleroderma 703 218 Sebaceous hyperplasia 707 219 Seborrheic eczema [books.google.de]

  LYMPHOMATOID DERMATITIS/ECZEMA Described in association with external sensitization, it is now recognised to occur in occasional cases of atopic dermatitis and in particular, those with high IgE levels 23. [slideshare.net]

  Lymphocytoma cutis is normally mistaken as psoriasis, eczema and dermatitis. [asiancancer.com]

  Anti-CD20 (rituximab) treatment improves atopic eczema J Allergy Clin Immunol. 2008;121:122–8 23. Graves JE, Nunley K, Heffernan MP. [journals.lww.com]

In the event that there is still uncertainty as to whether the lymphoid infiltrate represents a pseudolymphoma or a lymphoma, additional workup can be helpful. [plasticsurgerykey.com]

Staging workup should include bone marrow biopsy and CT of the abdomen to exclude extrathoracic disease. Lymphangiograms and bone scans could be part of the preoperative staging [65]. [cardiothoracicsurgery.biomedcentral.com]

• Borrelia Burgdorferi

  In endemic regions, Borrelia burgdorferi is the principal causative agent for LC. [ingentaconnect.com]

  Cases with known etiologies involve a reaction to tattoo dye, jewelry (especially gold), arthropod bites, medications, folliculitis, trauma, infections (ie, with Borrelia burgdorferi,molluscum contagiosum), vaccinations, and acupuncture. [thehealthscience.com]

  Also granuloma annulare and interstitial granulomatous dermatitis might be partly caused by Borrelia burgdorferi or similar strains. [sites.google.com]

  Clinical-pathologic correlation remains the criterion standard in the differential diagnosis. [6, 7, 8] Antibodies to Borrelia burgdorferi may be identified in 50% of patients with borrelial lymphocytoma. [img.medscape.com]

  Species of Borrelia burgdorferi complex that cause borrelial lymphocytoma in France. Br J Dermatol. 2009;161(1):174-6. [ PubMed ] Maraspin V, Cimperman J, Lotric-Furlan S, Ruzić-Sabljić E, Jurca T, Picken RN, Strle F. [on-lyme.org]

• Helicobacter Pylori

  pylori ), tattoos, acupuncture, trauma, gold jewelry, vaccinations, hyposensitization injections, or medications ( Figs. 146-1, ... [accessmedicine.mhmedical.com]

  pylori –related gastric mucosa-associated lymphoid tissue [MALT] lymphoma). [emedicine.medscape.com]

  pylori ) Sites where acupuncture needles were inserted References Laboratory Studies Biopsy is necessary to establish a diagnosis of lymphocytoma cutis and to exclude cutaneous lymphoma. [img.medscape.com]

  pylori ), tattoos, acupuncture, trauma, gold jewelry, vaccinations, hyposensitization injections, or medications ( Figs. 146-1, 146-2, 146-3, and 146-4 ). 1 – 9 Medications that may induce CLH include phenytoin, carbamazepine, phenobarbital, β blockers [plasticsurgerykey.com]

  pylori gastritis A型胃炎：type A gastritis 反応性胃炎：reactive gastritis 吻合部胃炎：stromal gastritis ◎Menetrier病 びらん：erosion ◎消化性潰瘍：peptic ulcer ◎過形成性ポリープ：hyperplastic polyp ◎胃底腺ポリープ：fundic gland polyp Cronkhite-Canada syndroma 胃腸管若年性ポリープ：gastrointestinal juvenile [medical-e.net]

The aim of this systematic review is to summarize all reported treatments for CPL. [ncbi.nlm.nih.gov]

We review here the treatment of pseudolymphoma of the skin according to its aetiology. We also suggest a treatment algorithm that may help physicians in choosing treatment. There is no previous systematic review of the treatment of CPL. [medicaljournals.se]

The prognosis of CPL is good, but the underlying disease process should be taken into account. If an antigenic stimulus is identified, it should be removed. In patients with idiopathic CPL, a close follow-up control strategy should be adopted. [ncbi.nlm.nih.gov]

Familial occurrence has been reported. [4] Prognosis Prognosis is good because lymphocytic infiltration of the skin may resolve spontaneously. Lymphocytic infiltration of the skin (LIS) is not associated with increased mortality. [emedicine.medscape.com]

[…] is associated with better prognosis as compared to the Asian type. [ijdpdd.com]

In view of the totally differing treatment modalities and prognosis, IHC with CD3, CD10, CD20 and LCA was done. [jomfp.in]

[…] studies and molecular analysis of clonality have been shown to be reliable tools, providing significant help in the differential diagnosis between primary cutaneous lymphoid malignancy and pseudolymphoma involving the skin, the identification of an etiological [ncbi.nlm.nih.gov]

Commonly occurring etiological causes have been tabulated along with salient histological features [Table 1]. [idoj.in]

Lymphocytoma Cutis: A Case Report Abstract Cutaneous pseudolymphomas are a group of benign reactive T- or B-cell lymphoproliferative processes of diverse etiology that simulate cutaneous lymphomas clinically and histologically. [synergypublishers.com]

Only cases with a B. burgdorferi etiology (typical locations, positivity of serologic and/or polymerase chain reaction (PCR) tests, clinical history) were included in the study. [ingentaconnect.com]

This form of the disease is a response to an infection due to Borrelia burgdorferi subsp afzelius that is transmitted by a tick bite. [1] Epidemiology Frequency United StatesNo data on US prevalence or incidence of lymphocytoma cutis are available. [thehealthscience.com]

No significant epidemiologic data are available regarding entities in the T-cell pattern pseudolymphoma spectrum. [emedicine.medscape.com]

This form of the disease is a response to an infection due to Borrelia burgdorferi subsp afzelius that is transmitted by a tick bite. [1] References Epidemiology Frequency United States No data on US prevalence or incidence of lymphocytoma cutis are available [img.medscape.com]

Case Overview lymphocytoma cutis Member Rated 0 Patient case no. 2292 Date added 14 June 2003 Patient details Age --Undetermined-- Localisation Trunk / back Description Primary Lesions Plaque / erythematous Nodule Pathophysiology tumors and proliferative [dermquest.com]

Pathophysiology In lymphocytoma cutis, lymphocytes and other inflammatory cells are recruited to a localized area of the skin in response to known or unknown stimuli. Most cases of lymphocytoma cutis are idiopathic. [thehealthscience.com]

Cutaneous lymphoid hyperplasia is the preferred term because it accurately describes the underlying pathophysiology of the lesion and is unlikely to be confused with terms used to describe various forms of cutaneous lymphoma. 1 – 6 In most cases, CLH [accessmedicine.mhmedical.com]

Ko, C.J., “Cutaneous pseudolymphoma: background, pathophysiology, etiolgy”, Medscape Reference, 2014, disponible en: http://emedicine. medscape.com/article/1099188-overview. [new.medigraphic.com]

[…] entity with a distinct biologic mechanism; however, the significant clinical overlap (ie, implicated drugs, symptomatology, and presentation) and some histologic overlap make the nosologic distinction of these entities difficult to resolve. [2, 5, 6] Pathophysiology [emedicine.medscape.com]

Your skin Holds body fluids in, preventing dehydration Keeps harmful microbes out, preventing infections Helps you feel things like heat, cold, and pain Keeps your body temperature even Makes vitamin D when the sun shines on it Anything that irritates [icdlist.com]

Antibacterial treatment is necessary in all patients to eliminate the spirochete, cure current disease, and prevent late sequelae. [sites.google.com]

Each of these techniques suffers from important disadvantages that may prevent their use for routine clinical pathology analysis of paraffin-embedded specimens. [nature.com]

Rituximab for prevention and treatment of graft-versus-host disease Int J Hematol. 2011;93:578–85 59. [journals.lww.com]

They suggest performing multiple confirmatory immunophenotyping tests to prevent misinterpretation (19). Cutaneous PSL can progress into a lymphoma. (7) Nihal et al. utilized the IHC and clonality study in 44 PSL patients. [ncbi.nlm.nih.gov]