Case Presentation A 46-year-old Caucasian female presented with a chief complaint of generalized hair loss for a duration of nine months. The patient stated that the hair loss was gradual in onset and had worsened over time. [cureus.com]

Cutaneous neurocristic hamartoma presenting as cutis verticis gyrata. Am J Dermatopathol, 36 (2014), pp. e66-e669 [4] M. Huerta-Brogeras, L.M. Fraqueiro, D. Martínez-Sánchez, E. Castaño, O.N. Perea, J. Borbujo. [elsevier.es]

Our patient presented intense pruritis, which had previously been treated with oral antihistamines and topical antipruritics, with no response. [actasdermo.org]

None of the cases presented were associated with pain. [scielo.org.co]

• Shagreen Patch

  Giant shagreen patch associated with spina bifida occulta in tuberous sclerosis. Pediatr Dermatol, 20 (2003), pp. 453-454 [8] S. Rai, P. Kalakoti, M.A. Syed, P.J. Thacker, R. Jain, G. Kalra. [elsevier.es]

• Night Sweats

  Her review of systems was otherwise unremarkable, specifically negative for weight loss, night sweats, and fatigue. On clinical physical exam, the patient appeared healthy and was in no acute distress; vital signs were within normal limits. [cureus.com]

Based on the clinical feature and examination findings, acromegaly was suspected. 1–3 Endocrine workup revealed elevated serum growth hormone (48.1 ng.ml; reference range 0–30.0 ng/ml), unsuppressed post-glucose growth hormone (PGGH) (60 min PGGH, 35.2 [academic.oup.com]

A full laboratory workup, including a complete blood count, biochemistry, urinalysis, magnetic resonance imaging, skin biopsy, and chromosome analysis revealed no significant alterations, and there were no relevant findings on ophthalmologic study. [actasdermo.org]

Workup In primary cases, no laboratory tests should be ordered. [emedicine.medscape.com]

Treatment fo CVG Treatment of CVG will depend on whether the final diagnosis is primary or secondary CVG. [donovanmedical.com]

[citation needed] Treatment[edit] Options for medical treatment for this condition have been limited to plastic surgery with excision of the folds by means of scalp reduction/surgical resection. [en.wikipedia.org]

Figure 2 Cutis verticis gyrata (CVG) after ten days of treatment with prednisone 30 mg/day. Superior-posterior view of cranium. Figure 3 Cutis verticis gyrata (CVG) after ten days of treatment with prednisone 30 mg/day. [scielo.isciii.es]

Treatment with capsaicin gel 0.075% was instated but the patient's condition worsened; oral gabapentin was then instated with no improvement, and both treatments were therefore suspended. [actasdermo.org]

What is the treatment of cutis verticis gyrata? The treatment of cutis verticis gyrata includes good scalp hygiene to avoid accumulations of secretions in the furrows of the scalp. [dermnetnz.org]

The patient was informed in a simple and understandable manner that a series of complementary examinations were necessary in order to find out the prognosis and treatment. [scielo.isciii.es]

The prognosis is benign. Other organ systems are spared and there is no malignant transformation of scalp tissue or brain parenchyma. [ncbi.nlm.nih.gov]

Treatment and prognosis Management depends on severity of the disease 2. In mild disease, good scalp hygiene is recommended to avoid accumulations of malodourous secretions in furrows 2. [radiopaedia.org]

Cutis verticis gyrata may be disfiguring, but the process is essentially benign, and the prognosis is good[1]. [statpearls.com]

Etiology The etiologies of cutis verticis gyrata can be classified as either primary or secondary 1-6: primary primary essential: no other associated anomalies primary non-essential: associated with neuropsychiatric or ophthalmologic anomalies secondary [radiopaedia.org]

Differentiation of primary and secondary forms of cutis verticis gyrata and currently recognized etiologies are also briefly reviewed. [ncbi.nlm.nih.gov]

The secondary etiology is due to underlying diseases, with no mental deficiency. [scielo.org.co]

Cutis verticis gyrata: three cases illustrating three different etiologies Amal Chamli University of Tunis El Manar Faculty of Medicine of Tunis Corresponding Author:[email protected] Author Profile Meriem Jones University of Tunis El Manar Faculty of [authorea.com]

Epidemiologic and Clinical Aspects. Acta Med Scand. 1964;175:115-27. 5 Harish V, Clarke F. Isolated cutis verticis gyrata of the glabella and nasal bridge: a case report and review of the literature. [scielo.br]

Journal Journal ID (nlm-ta): Pan Afr Med J Journal ID (iso-abbrev): Pan Afr Med J Journal ID (publisher-id): PAMJ Title: The Pan African Medical Journal Publisher: The African Field Epidemiology Network ISSN (Electronic): 1937-8688 Publication date (Electronic [scienceopen.com]

Epidemiologic and clinical aspects”. Acta Med Scand. vol. 175. 1964. pp. 115-27. (Large analysis in Swedish population that provides epidemiologic, clinical, and genetic data concerning CVG.) Akesson, HO. [dermatologyadvisor.com]

Sections Continuing Education Activity Introduction Etiology Epidemiology Pathophysiology Histopathology History and Physical Evaluation Treatment / Management Differential Diagnosis Prognosis Complications Deterrence and Patient Education Enhancing Healthcare [pubmed.ncbi.nlm.nih.gov]

Epidemiologic and Clinical Aspects. Acta Med Scand., 175 (1964), pp. 115-127 [5] V. Harish, F. Clarke. Isolated cutis verticis gyrata of the glabella and nasal bridge: a case report and review of the literature. [anaisdedermatologia.org.br]

Author information 1 Pediatric Highly Intensive Care Unit, Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Italy. 2 Division of Neuroradiology, Fondazione [ncbi.nlm.nih.gov]

A hormonal influence has been postulated as this disorder usually manifests in postpubertal men.[5][3] Secondary cutis verticis gyrata is considered to be a manifestation of a variety of underlying causes, and the pathophysiology, in this case, can be [statpearls.com]

Sections Continuing Education Activity Introduction Etiology Epidemiology Pathophysiology Histopathology History and Physical Evaluation Treatment / Management Differential Diagnosis Prognosis Complications Deterrence and Patient Education Enhancing Healthcare [pubmed.ncbi.nlm.nih.gov]

^ "Cutis Verticis Gyrata: Background, Pathophysiology, Etiology". February 2019. ^ Unna PG. Cutis verticis gyrata. Monatschr Prakt Derm. 1907. 45:227-33. ^ Levine, Norman (2004). Dermatology Therapy A-Z Essentials. [en.wikipedia.org]

Early diagnosis is extremely important to prevent the development of malignant melanoma. [ncbi.nlm.nih.gov]

The surgical technique must spare the scalp vascularization to prevent healing complications and to allow for a subsequent surgery if needed. [cureus.com]

Surgery is the morphological treatment of choice for cutis verticis gyrata, but does not prevent the continued progression of the disease. [docteurmedarddechardon.co.uk]

Local scalp hygiene is important to avoid secretion accumulation, maceration, unpleasant odor, and also to prevent secondary infections[3][4][5] Primary cutis verticis gyrata is a benign cutaneous disorder. [statpearls.com]