Presentation
Pediatricians often are unaware of other presenting symptoms of the disease. As a consequence, diagnosis is often delayed by months and even years. One of the presenting signs of adrenal insufficiency is hyperpigmentation. [ncbi.nlm.nih.gov]
Cardiovascular
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Cyanosis
STUDIES ON CYANOSIS : II. SECONDARY CAUSES OF CYANOSIS. J. Exp. Med. 1919 Sep 01;30(3):271-93. [PMC free article: PMC2126678] [PubMed: 19868358] 5. Lundsgaard C. STUDIES ON CYANOSIS : I. PRIMARY CAUSES OF CYANOSIS. J. Exp. [ncbi.nlm.nih.gov]
Differential diagnosis Central cyanosis in neonates Transient cyanosis after delivery: central cyanosis should clear within a few minutes of the birth. Peripheral cyanosis clears within a few days. [patient.info]
Peripheral cyanosis Peripheral cyanosis is a dusky or bluish tinge to the fingers and toes and may occur with or without central cyanosis (ie, with or without hypoxemia). [emedicine.com]
Workup
On further laboratory workup, lupus anticoagulant studies, including a mixing study, diluted Russell viper venom test, and hexagonal phase phospholipid neutralization test, were abnormal. [mdedge.com]
Serum
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Arterial Oxygen Saturation Increased
However, arterial oxygen saturations increased gradually over nine months to 90-93% and 95-100% after three years. [ncbi.nlm.nih.gov]
Treatment
Etiology for hypoxemia, treatment strategy, and patient outcomes were examined for each patient. [ncbi.nlm.nih.gov]
Treatment Treatment starts by identifying and correcting underlying reasons for constricted blood flow. Timely and appropriate treatment can help reduce any potential complications. [verywellhealth.com]
Treatment depends on the cause. Page last reviewed: 10 August 2017 Next review due: 10 August 2020 [nhs.uk]
Prognosis
Patients with Hb Kansas do not require any specific treatment and the prognosis is good. In patients with unexplained cyanosis, we should thus consider Hb variants, including Hb Kansas and avoid unnecessary investigations and managements. [ncbi.nlm.nih.gov]
The prognosis of cyanosis is excellent in these cases, as Hb F declines post natally and is replaced by normal Hb A. Supplemental O 2 may be required for several months during the postnatal period as was the case with this patient. [bloodjournal.org]
Prognosis If the underlying condition (such as heart or lung disease) can be properly treated, the skin will return to its normal shade. Resources Books Carolson, Karen J., Stephanie A. Eisenstat, and Terra Ziporyn. [medical-dictionary.thefreedictionary.com]
15/20]) and had no recurrent thrombosis (87% [13/15]) at follow-up. 5 Data also are emerging on the role of eculizumab, an anti-C5 antibody that inhibits the terminal complement cascade, as a therapy in difficult-to-treat or refractory CAPS. 6-8 The prognosis [mdedge.com]
Cyanosis can present in the setting of elevated pulmonary artery pressure, as in Eisenmenger syndromes having a poor prognosis. [j-pcs.org]
Etiology
Etiology for hypoxemia, treatment strategy, and patient outcomes were examined for each patient. [ncbi.nlm.nih.gov]
Although the common feature in each of these patients is cyanosis, the etiologies differ. View this table: In this window In a new window Table 1. TABLE. [pedsinreview.aappublications.org]
Epidemiology
He has since completed further training in emergency medicine, clinical toxicology, clinical epidemiology and health professional education. [lifeinthefastlane.com]
Summary Epidemiology Prevalence of cystinuria has high ethnogeographic variation, ranging from 1:2,500 in the Libyan Jewish population to 1:100,000 in Sweden. The mean global value is estimated at 1:7,000. [orpha.net]
An overview of the epidemiology, risk factors, clinical manifestations, and management of pelvic organ prolapse in women. . Accessed July 30, 2014. Mahajan ST. Pelvic organ prolapse in women: Surgical repair of anterior vaginal wall prolapse. . [mayoclinic.org]
Pathophysiology
The goal of this article is to help the reader understand the etiology and pathophysiology of cyanosis and to formulate an approach to its differential diagnosis. Copyright 2015, SLACK Incorporated. [ncbi.nlm.nih.gov]
The goal of this article is to help the reader understand the etiology and pathophysiology of cyanosis and to formulate an approach to its differential diagnosis. [Pediatr Ann. 2015;44(2):76–80.] [healio.com]
Peripheral cyanosis: Tissue extracts more than normal amounts of O2 from the blood Hypoperfusion Vasoconstriction to cold air or water Arterial insufficiency Venous insufficiency Acrocyanosis: Painless, symmetrical, cyanosis in distal parts of body, the pathophysiologic [emergency.unboundmedicine.com]
The list of the pathophysiological causes and the most common disorders summarized in Figure 1. Clearly, it can be a formidable task to reach the right diagnosis in a neonate with central cyanosis. [hindawi.com]
Prevention
Lymph System Problems Lymphatic dysfunction can prevent lymph fluid from flowing and draining properly. This can result in swelling (edema), which can hamper proper blood flow. 6. [hamiltongrovehealth.blog]
Hospital for Sick Children Health A-Z Search a complete list of child health articles expand_more View All Drug A-Z Search a list of articles about medications expand_more View All Learning Hubs Browse a complete list of content groups Healthy Living & Prevention [aboutkidshealth.ca]
It’s important to restore oxygen to body tissues as soon as possible in order to prevent complications. In many cases, blue lips or skin can be a sign of a life-threatening emergency. [healthline.com]
If cyanosis is limited to one area of the body, it could be caused by a blood clot or some type of blockage preventing blood from flowing to that part of the body. [study.com]
This happens when the blood vessels narrow, preventing blood from reaching the extremities. Low blood pressure. Low blood pressure is when there is not enough pressure to push blood and oxygen to the hands and feet. [medicalnewstoday.com]