Protease proteinase 3 (PR3) and myeloperoxidase (MPO) ANCA are present in almost all patients with MPA and GPA in the active generalized stage of the disease; in EGPA, ANCA are present in less than 40 percent and their presence is associated with typical [thermofisher.com]

It should be noted that in this systematic review RCTs and CCTs including both children and adults were only eligible for inclusion if the maximal age of the participants did not exceed 30 years or if data were presented separately for patients aged less [cochranelibrary.com]

There is some evidence on anti‐tumour efficacy and adverse effects of treatment with cyclophosphamide as compared to treatment with ifosfamide from studies including both children and adults. [cochranelibrary.com]

[…] skin Vasculitis diagnosis: Testing for differential diagnosis Prompt recognition of vasculitis either as a new presentation or a clinical relapse is key to optimizing management and preventing organ damage.6 The good news is that prompt diagnosis and treatment [thermofisher.com]

Although the prognosis of the different types of sarcomas in children still depends on several prognostic factors, such as the presence of metastases, tumour volume and primary tumour site, it has been improving since the introduction of polychemotherapy [cochranelibrary.com]

Prompt recognition of vasculitis either as a new presentation or a clinical relapse is key to optimizing management and preventing organ damage.6 ANCA-associated vasculitides Vasculitis is a condition that causes inflammation of vessel walls.3 ANCA-associated [thermofisher.com]