Cyclosporine was effective in decreasing the eosinophil count without the elimination of abnormal T cell clones in the present case. Cytotoxic agents may be necessary to cure this serious disease. [ncbi.nlm.nih.gov]

Usually presents as oliguria in patients who have received a cadaveric renal transplant but may also occur in native kidneys in patients who are treated with high doses. [aic.cuhk.edu.hk]

• Pain

  Check with your doctor immediately if any of the following side effects occur: More common Abdominal or stomach pain or tenderness back pain black, tarry stools blurred vision chest pain chills clay colored stools cloudy urine cough dark urine decrease [mayoclinic.org]

  Contact your doctor as soon as possible if any of the following are noticed: Severe headache, signs of infection (e.g. fever of 38.5°C), persistent nausea, vomiting, or abdominal pain, muscle pain or cramping, severe tremors, unusual swelling of extremities [healthhub.sg]

  We will also test effects of therapy on skin sensation and pain perception because the molecule which Cyclosporine binds to (calcineurin) is also found in nerves that conduct pain signals. [clinicaltrials.gov]

  Benign chronic familial pemphigus (BFCP) is an autosomal dominant dermatosis characterized by flares of painful and often debilitating blistering lesions in high friction areas of the body such as the groin, axillae, lateral neck, and intergluteal cleft [ncbi.nlm.nih.gov]

• Fever

  However, 6 patients (21.4%) failed to become afebrile within 5 days after the start of CyA and/or high fever returned after becoming afebrile within 5 days. [doi.org]

  He had development of severe and generalized myalgia and fever after the eighth application of pegylated interferon-α and increasing doses of cyclosporine. Laboratorial tests showed acute renal failure and significant increase in creatine kinase. [ncbi.nlm.nih.gov]

• Weakness

  His bilateral thigh muscle atrophy showed improvement and lower limb weakness was obviously alleviated and he could stand and walk with the help of others 4 weeks later. [ncbi.nlm.nih.gov]

  or feeling of sluggishness weakness weight loss Other side effects not listed may also occur in some patients. [mayoclinic.org]

  Get medical help right away if you have any very serious side effects, including: mental/mood changes (such as confusion, difficulty concentrating), vision changes, problems with speech, clumsiness, loss of coordination, weakness on one side of the body [webmd.com]

• Fatigue

  […] muscle, bone, or joint pain Symptoms of a cyclosporine overdose include: vomiting fatigue rapid heart rate, or tachycardia jaundice, a yellowing of the skin and whites of the eyes that may indicate liver damage kidney damage swelling of the arms, hands [medicalnewstoday.com]

  If you experience unexplained nausea, fatigue, muscle weakness or tingling sensations, contact your doctor, as these may be signs of too much potassium. [uniprix.com]

  […] bruising easily, mouth sores, abdominal pain, pale stool, darkened or increased amount of urine, weight loss or gain, muscle spasms or weakness, fast or irregular heartbeat, muscle spasms, confusion, tingling in the hands or feet, problems in hearing, fatigue [verywellhealth.com]

• Epilepsy

  It should be taken into account in infants and children, especially in high-risk groups, such as patients with liver disease or epilepsy. [tellmegen.com]

  (for the treatment of heart conditions), immunosuppressants including tacrolimus and ciclosporin, sildenafil (for male impotence), statins (used to lower lipid levels in the blood), phenobarbital, phenytoin or carbamazepine (used in the treatment of epilepsy [mymemory.translated.net]

  These include antibiotics (such as rifamipicin) and anti-epilepsy medication (such as carbamazeapine). Certain drugs can affect kidney function and have to be used with caution when taken in combination with cyclosporin. [dermcoll.edu.au]

  Three generic medicines received a positive opinion from the CHMP : Entecavir Accord (entecavir) and Entecavir Mylan (entecavir), both for the treatment of chronic hepatitis B; and Lacosamide Accord (lacosamide), for the treatment of epilepsy. [ema.europa.eu]

  Those who should not take the oral cyclosporine solution include children, pregnant women and those who are breastfeeding, and people who have liver disease or epilepsy. Cyclosporine can also reduce the effectiveness of vaccines. [medicalnewstoday.com]

• Nausea

  Shaking, headache, dizziness, unusual growth of body hair, nausea / vomiting, diarrhea, stomach upset, or flushing may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. [webmd.com]

  […] increased hair growth acne (pimples), oily skin mild nausea (upset stomach) vomiting (throwing up) diarrhea (loose bowel movements) leg cramps tenderness or swelling of the gums (Carefully brush your child's gums or use a cool teething ring. [childrensmn.org]

  Other side effects of cyclosporine More hair growth Nausea (feeling you need to vomit) Diarrhea Headache Growth of your gums Long-term kidney or liver damage Rare side effects are a higher risk of skin cancers and lymphoma. [uihc.org]

  Below are some of the symptoms of Cyclosporine side effects that one needs to look for – • Indicated by stomach flush/upset, diarrhoea, vomiting/nausea, unusual body hair growth, dizziness, headache, or shaking, may occur, over a prolonged time duration [portea.com]

• Abdominal Pain

  Contact your doctor as soon as possible if any of the following are noticed: Severe headache, signs of infection (e.g. fever of 38.5°C), persistent nausea, vomiting, or abdominal pain, muscle pain or cramping, severe tremors, unusual swelling of extremities [healthhub.sg]

  pain ), easy bruising/bleeding, unusual tiredness, muscle weakness /spasms, slow/irregular heartbeat, numb/tingling skin, severe leg pain. [webmd.com]

  Other possible side effects include headaches, nausea, vomiting, abdominal pain or indigestion, swelling of the hands or feet, tremors, increased hair growth, gum swelling, muscle cramps, or numbness and tingling of the hands or feet. [rheumatology.org]

  pain, pale stool, darkened or increased amount of urine, weight loss or gain, muscle spasms or weakness, fast or irregular heartbeat, muscle spasms, confusion, tingling in the hands or feet, problems in hearing, fatigue. [verywellhealth.com]

• Gingival Hypertrophy

  Other adverse effects: digestive disorders, hepatotoxicity (transient), hirsutism / hypertrichosis, angioedema, gingival hypertrophy, tremor, headache, paresthesia, myalgia, asthenia and hyperlipidemia. [tellmegen.com]

  […] fibrous tissue is normally observed, which is comparable with the histology of fibroadenomas that may reach a large size and be non-reversible, depending on the degree of fibrosis. 2 This histological profile is similar to that of cyclosporine A-induced gingival [revistanefrologia.com]

  These findings may precede kidney functions alterations.13,14 Therefore, the safest method to evaluate renal risk is histological analysis.2 Other side effects are arterial hypertension, hyperlipidemia, hypertrichosis, gingival hypertrophy and hyperuricemia [bjn.org.br]

  Other neurologic side effects include tremor, asthenia, and fatigue. 91 Psychiatric side effects have also been reported. 8 Patients with a history of seizures should be made aware that CSA can lower the seizure threshold. 8 Gingival hypertrophy, commonly [aad.org]

• Hypertension

  […] and rarely severe hypertension may occur; incidence decreases over time; antihypertensive therapy may be required in recipients of kidney, liver, and heart allografts treated with cyclosporine; potassium-sparing diuretics should not be used to treat [reference.medscape.com]

  (DBP>100mgHg) Treat with anti-hypertensive (check for interactions) or reduce dose Cyclosporin may give rise to a number of other side-effects which, if distressing to the patient, may require dose reduction or discontinuation. [nhsgrampian.org]

  It may be accompanied by hypertension, hyperuricemia, hyperkalemia, hypomagnesemia. [tellmegen.com]

  Patients with psoriasis who have been treated with PUVA, methotrexate or immunosuppressants, UVB, coal tar, or radiation are at increased risk for skin malignancies, hypertension, and renal dysfunction. This medication contains cyclosporine. [rxlist.com]

• Muscle Spasm

  spasms or weakness, fast or irregular heartbeat, muscle spasms, confusion, tingling in the hands or feet, problems in hearing, fatigue. [verywellhealth.com]

  spasms (tetany) or twitching nausea and vomiting nervousness painful or difficult urination pounding in the ears shakiness in the legs, arms, hands, or feet shortness of breath skin rash slow or fast heartbeat sore throat sores, ulcers, or white spots [mayoclinic.org]

  However, listed below are some symptoms, if any of these symptoms occur, the patient needs to get medical intervention – o Severe leg pain o tingling skin/ Numb o irregular/ Slow heartbeat o Muscle spasms /weakness o Easy bleeding/bruising o Signs of [portea.com]

  Tell your doctor immediately if any of these symptoms of infection occur: fever, sore throat, flu -like symptoms, painful urination.Tell your doctor right away if you have any serious side effects, including: muscle spasms / weakness, fast/irregular heartbeat [medicinenet.com]

• Arthralgia

  anemia, carcinoma, leukopenia, lymphadenopathy Hepatic: Hyperbilirubinemia Infection: Abscess (including renal), bacterial infection, candidiasis, fungal infection, herpes simplex infection, herpes zoster, viral infection Neuromuscular & skeletal: Arthralgia [drugs.com]

  […] moniliasis, tonsillitis, viral infection Hematologic: anemia, epistaxis, leukopenia, lymphadenopathy Liver and Biliary System: bilirubinemia Metabolic and Nutritional: diabetes mellitus, hyperkalemia, hyperuricemia, hypoglycemia Musculoskeletal System: arthralgia [web.archive.org]

• Ulcer

  In one patient, additional scraping of the bottom of the ulcer was needed. In patients with vernal shield ulcers, frequent installation of low-concentration cyclosporine eye drops seems to have a promising therapeutical value. [ncbi.nlm.nih.gov]

  Results of Cyclosporine or Placebo Administration in 20 Patients with Severe Ulcerative Colitis. [doi.org]

  Cyclosporine in severe ulcerative colitis refractory to steroid therapy. N Engl J Med. 1994;330(26):1841-1845. 2. Kornbluth A, Present DH, Lichtiger S, Hanauer S. Cyclosporin for severe ulcerative colitis: a user’s guide. [healio.com]

  Ciclosporin is also used in the treatment of some autoimmune diseases including psoriasis, atopic dermatitis, rheumatoid arthritis, nephrotic syndrome and ulcerative colitis. [gloshospitals.nhs.uk]

  In addition, the ability of cyclosporin to inhibit T-cell activation has been shown to have a role in the treatment of diseases such as nephrotic syndrome, refractory Crohn's disease and ulcerative colitis, biliary cirrhosis, aplastic anemia, rheumatoid [abcam.com]

• Hirsutism

  Other adverse effects: digestive disorders, hepatotoxicity (transient), hirsutism / hypertrichosis, angioedema, gingival hypertrophy, tremor, headache, paresthesia, myalgia, asthenia and hyperlipidemia. [tellmegen.com]

  Common side effects of cyclosporine include headache, dizziness, paresthesias, neuropathy, tremor, hypertension, hyperlipidemia, nephropathy, acne, hirsutism and gum hyperplasia. [livertox.nih.gov]

  […] anemia, leukopenia, thrombocytopenia Metabolic: hyperglycemia, hypomagnesemia, hyperuricemia, hyperkalemia, metabolic acidosis Musculoskeletal: muscle and joint pain Respiratory: cough, dyspnea, Pneumocystis jiroveci pneumonia, bronchospasm Skin: acne, hirsutism [medical-dictionary.thefreedictionary.com]

  We did not observe hypertension or hirsutism in this cohort in the prescribed doses. Discussion The responses to cyclosporin in chronic ITP were observed from 40–55% in published studies of patients with small numbers 2–6. [haematologica.org]

  Some signs or symptoms of cyclosporin toxicity are: kidney damage high blood pressure tremors bleeding, swelling, overgrowth of gums hirsutism hyperlipidaemia Peak concentrations of samples collected 2 hours post dose are sometimes tested in transplant [labtestsonline.org.au]

• Hypertrichosis

  […] component of all immunosuppressive protocols to control transplant rejection for solid organ graft recipients Nephrotoxicity is major concern ( Clin J Am Soc Nephrol 2009;4:481 ) Nephrotoxic, hepatotoxic and neurotoxic Also causes gingival hyperplasia, hypertrichosis [pathologyoutlines.com]

  Hypertrichosis, gingival hyperplasia, and neurological and gastrointestinal effects are the most common adverse events in cyclosporin recipients, but are usually mild to moderate and resolve on dosage reduction. [ncbi.nlm.nih.gov]

  Other adverse effects: digestive disorders, hepatotoxicity (transient), hirsutism / hypertrichosis, angioedema, gingival hypertrophy, tremor, headache, paresthesia, myalgia, asthenia and hyperlipidemia. [tellmegen.com]

  As for the side effects, 73% (n=24) presented mild to moderate gingival hyperplasia and 79% (n=26) mild to moderate hypertrichosis. [bjn.org.br]

• Eczema

  More Find an Article popular topics advocacy allergies alternative treatment ask a doctor atopic-dermatitis biologics burden of disease community comorbidities Dupixent eczema eczema awareness month eczema expo eczema warrior eczema warriors inflammation [nationaleczema.org]

  Types & treatments Childhood eczema Adult eczema Insider secrets Types of hair loss Treatment for hair loss Causes of hair loss Hair care matters Insider secrets What is psoriasis Diagnosis & treatment Skin, hair & nail care Triggers Insider secrets What [aad.org]

  In psoriasis and eczema cyclosporin is not used continuously for longer than 2 years to prevent permanent effects on kidney function and blood pressure. [dermcoll.edu.au]

  Common skin conditions that ciclosporin is used to treat are atopic eczema / dermatitis and psoriasis. [dermnetnz.org]

  D004485 HP:0000964 Eczema 3 ClinicalTrials Glomerulosclerosis, Focal Segmental D005923 EFO:0004236 focal segmental glomerulosclerosis 3 ClinicalTrials Leukemia, Prolymphocytic, T-Cell D015461 EFO:1000560 T-Cell Prolymphocytic Leukemia 2 ClinicalTrials [ebi.ac.uk]

• Pruritus

  […] scar, eyelid pruritus, iridocyclitis. [santen.com]

  […] efficacy not established in children 1 Geriatric Use No substantial differences in safety and efficacy relative to younger adults. 1 Common Adverse Effects Ocular burning, conjunctival hyperemia, discharge, epiphora, ocular pain, foreign body sensation, pruritus [drugs.com]

  Other reactions reported in 1% to 5% of patients included conjunctival hyperemia, discharge, epiphora, eye pain, foreign body sensation, pruritus, stinging, and visual disturbance (most often blurring). 6.2 Post-marketing Experience The following adverse [dailymed.nlm.nih.gov]

• Facial Swelling

  swelling inability to move part or all of the body (paralysis) seizures signs of a severe allergic reaction (e.g., swelling of the mouth, tongue, or eyes) Some people may experience side effects other than those listed. [uniprix.com]

• Kidney Failure

  Problems with kidney function, including kidney failure, and hypertension can occur in cases where the drug is used for over one year. [aocd.org]

  Avoid using cyclosporine for more than 2 years, as this increases the chance of kidney failure. Biologic medications are much safer options in patients with severe disease necessitating systemic treatment. [the-dermatologist.com]

  Cyclosporine can cause serious side effects, including kidney failure or life-threatening infection. While using cyclosporine, you will need frequent blood tests to be sure cyclosporine is not causing harmful effects. [drugs.com]

• Hot Flushes

  Coadministration of cyclosporine and aliskiren in these subjects also resulted in an increase in the number and/or intensity of adverse events, mainly headache, hot flush, nausea, vomiting, and somnolence. [dailymed.nlm.nih.gov]

  Your pharmacist may be able to advise you on managing side effects. acne or oily skin constipation decreased appetite diarrhea fatigue headache, including migraine hot flushes increase in hair growth leg cramps nausea night sweats trembling hands (tremor [uniprix.com]

  The vascular disorders included events of hot flushes and orthostatic hypotension. [doi.org]

• Amenorrhea

  Besides weight loss and disturbances in body image, the patient developed alopecia, bradycardia, and persistent secondary amenorrhea. [ncbi.nlm.nih.gov]

• Headache

  […] hair excessive, chronic diarrhea, tingling of tongue, finger tips and toes) Burden Not at all hard to take Dosage: 150 mg Daily Advice & Tips: When I was preparing my body for my transplant, I was taking a large dose of Neoral that gave me migraine headaches [patientslikeme.com]

  Headache This medication may cause headaches or migraines. Headache can also be a sign of elevated blood pressure, so this side effect should be reported to your provider for further evaluation. [oncolink.org]

  Call your doctor right away or go to the Emergency Department if your see any of these side effects: Fever, chills Cough or sore throat Blood in urine, difficulty urinating, or pain with urination Severe headache Seizures Confusion Shortness of breath [nephcure.org]

  Other side effects of cyclosporine More hair growth Nausea (feeling you need to vomit) Diarrhea Headache Growth of your gums Long-term kidney or liver damage Rare side effects are a higher risk of skin cancers and lymphoma. [uihc.org]

• Seizure

  Both cyclosporine and magnesium depletion may lower the seizure threshold, and treatment with magnesium may improve symptoms or prevent recurrence of seizures without the use of antiepileptic drugs, which may interfere with cyclosporine metabolism (eg [ahajournals.org]

  […] hypertension as cyclosporine may cause hyperkalemia; calcium antagonists can be effective but can interfere with cyclosporine metabolism Gingival hyperplasia may occur; avoid concomitant nifedipine administration in patients who develop gingival hyperplasia Seizures [reference.medscape.com]

  As noted above, one patient treated with cyclosporine had a grand mal seizure after the initiation of therapy but had no more seizures after cyclosporine was discontinued. [doi.org]

  There had been no previous episodes of similar headaches or seizures. [casesjournal.biomedcentral.com]

  Caution is advised if you have liver disease, alcohol dependence, seizures, or any other condition that require you to limit/avoid alcohol in your diet. Caution is also advised if you are pregnant or breast-feeding. [medicinenet.com]

• Confusion

  Cautions Discusses conditions that may cause diagnostic confusion, including improper specimen collection and handling, inappropriate test selection, and interfering substances The recommended therapeutic ranges described above apply to trough specimens [mayomedicallaboratories.com]

  Call your doctor right away if you have signs like feeling confused, lowered alertness, change in eyesight, loss of eyesight, seizures, or very bad headache. Talk with your doctor before getting any vaccines. [drugs.com]

• Encephalopathy

  Furthermore, neither patient showed any adverse effects, such as hypertension, encephalopathy, or chronic nephrotoxicity, to the CyA treatment.In conclusion, these results suggest that CyA may be a safe and effective treatment for steroid-resistant severe [ncbi.nlm.nih.gov]

  Posterior Reversible Encephalopathy Syndrome (PRES) In rare cases this medication has caused a neurological disorder called posterior reversible encephalopathy syndrome (PRES), also called reversible posterior leukoencephalopathy (RPLS). [oncolink.org]

  Current Issue Latest Articles Posterior reversible encephalopathy syndrome Cleveland Clinic Journal of Medicine March 2020, 87 (3) 131-132; DOI: https://doi.org/10.3949/ccjm.87a.18139 On day 4, his blood pressure was 209/93 mm Hg, and CT showed new vasogenic [ccjm.org]

  […] rejection, ulcerative colitis, autoimmune disease, schistosomiasis; it may be of use in aplastic anemia, in combination with antilymphocyte globulin and methylprednisone for psoriasis Adverse effects Nephrotoxicity, HTN, neurotoxicity–eg, tremor, seizures, encephalopathy [medical-dictionary.thefreedictionary.com]

• Paresthesia

  Other adverse effects: digestive disorders, hepatotoxicity (transient), hirsutism / hypertrichosis, angioedema, gingival hypertrophy, tremor, headache, paresthesia, myalgia, asthenia and hyperlipidemia. [tellmegen.com]

  Common side effects of cyclosporine include headache, dizziness, paresthesias, neuropathy, tremor, hypertension, hyperlipidemia, nephropathy, acne, hirsutism and gum hyperplasia. [livertox.nih.gov]

  […] with antilymphocyte globulin and methylprednisone for psoriasis Adverse effects Nephrotoxicity, HTN, neurotoxicity–eg, tremor, seizures, encephalopathy, headache, coma, hyperlipidemia, hyperkalemia, hypomagnesemia, HTN, anemia, anaphylaxis, nausea, paresthesias [medical-dictionary.thefreedictionary.com]

  These include paresthesias, which were noted in four study patients, and seizures, which occurred in one patient. [doi.org]

  Adverse reactions CNS: tremor, headache, seizures, confusion, paresthesia. CV: hypertension, flushing. EENT: sinusitis. GI: gum hyperplasia, oral candidiasis, nausea, vomiting, diarrhea, abdominal discomfort. GU: nephrotoxicity. [glowm.com]

• Hyperuricemia

  Noordzij and associates indicate how widespread the problem of cyclosporine-related hyperuricemia and gout is. They demonstrate the accentuation of hyperuricemia with diuretic agents, which is similar to our own observations. [doi.org]

  Common side effect of MZ is hyperuricemia which presumably caused acute renal failure of this aged marginal donor kidney. [ncbi.nlm.nih.gov]

  […] cyclosporine levels usually by inhibition or induction of CYP3A4 or P-gp or both Occasionally, patients develop a syndrome of thrombocytopenia and thrombotic microangiopathic hemolytic anemia may result in graft failure Significant hyperkalemia and hyperuricemia [reference.medscape.com]

  It may be accompanied by hypertension, hyperuricemia, hyperkalemia, hypomagnesemia. [tellmegen.com]

• Hyperglycemia

  […] peptic ulcer, mouth sores, difficulty swallowing, anorexia, upper GI bleeding, pancreatitis GU: gynecomastia, hematuria, nephrotoxicity, renal dysfunction, glomerular capillary thrombosis Hematologic: anemia, leukopenia, thrombocytopenia Metabolic: hyperglycemia [medical-dictionary.thefreedictionary.com]

  The diagnosis of CAN is often one of exclusion because of concomitant use of other neurotoxic agents such as methylprednisolone11 or the common presence of other factors such as hyponatremia, hypomagnesemia, or hyperglycemia that can mimic many of the [ahajournals.org]

  Siesjö, Effects of Preischemic Hyperglycemia on Brain Damage Incurred by Rats Subjected to 2.5 or5 Minutes of Forebrain Ischemia, Stroke, 10.1161/01.STR.27.9.1592, 27, 9, (1592-1602), (1996). B. K. Siesjö and P. [doi.org]

  […] clinical trials of kidney, heart, and liver transplants: The following reactions occurred in 2% or less of patients: allergic reactions, anemia, anorexia, confusion, conjunctivitis, edema, fever, brittle fingernails, gastritis, hearing loss, hiccups, hyperglycemia [dailymed.nlm.nih.gov]

  Two-year follow-up results were improvement in creatinine and lipid profile, with significantly fewer cardiovascular events without differences in acute rejection or new-onset hyperglycemia incidences after conversion [ 52 ]. [omicsonline.org]

• Creatinine Increased

  Adverse Effects and their Management Serum creatinine increases >30% of baseline value Reduce dose by 25% Serum creatinine increases >50% of baseline value Reduce dose by 50% If serum creatinine dose not decrease within 1 month Stop drug and contact rheumatologist [nhsgrampian.org]

  There was a slight increase in the mean serum creatinine during the study, but there was no significant difference between treatment groups (Fig. 3). [academic.oup.com]

  Serum creatinine improved in all but one patient after discontinuation of cyclosporine. The “maximal creatinine increase” appears to be a factor in predicting cyclosporine nephropathy. [web.archive.org]

• Creatinine Increased

  Adverse Effects and their Management Serum creatinine increases >30% of baseline value Reduce dose by 25% Serum creatinine increases >50% of baseline value Reduce dose by 50% If serum creatinine dose not decrease within 1 month Stop drug and contact rheumatologist [nhsgrampian.org]

  There was a slight increase in the mean serum creatinine during the study, but there was no significant difference between treatment groups (Fig. 3). [academic.oup.com]

  Serum creatinine improved in all but one patient after discontinuation of cyclosporine. The “maximal creatinine increase” appears to be a factor in predicting cyclosporine nephropathy. [web.archive.org]

METHODS: We retrospectively evaluated C2 levels in 38 patients (17 males, 5.2 ± 2.9 years old) with SDNS at treatment initiation, at 6, 12 and 18 months during treatment, and at the time of kidney biopsy, 2-year after treatment initiation. [ncbi.nlm.nih.gov]

Her clinical features were compatible with TAFRO syndrome proposed as a variant of multicentric Castleman's disease, that is occasionally associated with poor prognosis. Treatment with corticosteroid improved her symptoms partially. [ncbi.nlm.nih.gov]

(B) Mean mRNA expression of oxidative phosphorylation proteins in diffuse large B-cell lymphoma patients with the worst prognosis vs. those with the best prognosis. [doi.org]

Lichen striatus is an acquired, benign, linear inflammatory dermatosis characterized by a sudden skin eruption along Blaschko's lines that usually is not associated with specific etiologic agents. [ncbi.nlm.nih.gov]

Moritz, Neutropenia in dogs: etiology and prognostic factors, Tierärztliche Praxis Ausgabe K: Kleintiere / Heimtiere, 44, 5, (307), (2016). [doi.org]

The epidemiology of dry eye disease: report of the Epidemiology Subcommittee of the International Dry Eye WorkShop (2007). Ocul Surf 2007; 5 : 93–107. 2. Hossain P, Konstantopoulos A. Blepharitis: remains a diagnostic enigma. [nature.com]

Pars planitis: Epidemiology, clinical characteristics, management and visual prognosis. Vol. 10, Journal of Ophthalmic and Vision Research. 2015. p. 469–80. ↑ Nussenblatt RB, Palestine AG, Chan CC, Breen L, Caruso R. [eyewiki.aao.org]

Epidemiology In published studies, the incidence of cancer in renal transplant recipients ranges from 2.3–31% [ 3 ], although this estimate is limited by the focus of individual studies on specific populations and a lack of long-term follow-up, thus potentially [doi.org]

Although other tumors (12 skin cancers, 24 solid tumors of diverse types, and 1 multiple myeloma) were also reported in this survey, epidemiologic analyses did not support a relationship to cyclosporine other than for malignant lymphomas. [web.archive.org]

Nussenblatt and his collaborators delved into the most significant adverse effect of CsA, renal toxicity, and helped elucidate the pathophysiology of renal injury. [ncbi.nlm.nih.gov]

[…] cyclosporin (also cyclosporin A, cyclosporine ) noun mass noun Medicine A drug with immunosuppressive properties used to prevent the rejection of grafts and transplants. A cyclic peptide, it is obtained from a fungus. [en.oxforddictionaries.com]

World English Dictionary ciclosporin or cyclosporin (ˌsaɪkləʊˈspɔːrɪn) — n a drug extracted from a fungus and used after organ transplantation to suppress the body's immune mechanisms, and so prevent rejection of an organ cyclosporin or cyclosporin — [web.archive.org]

Cyclosporine is a cyclic polypeptide with immunosuppressant properties that is used for the prevention of graft-versus-host disease in hematopoietic stem cell transplantation patients, for the prevention of graft rejection in solid organ transplant patients [accesspharmacy.mhmedical.com]

Dec 8, 2016 (Started Jun 01, 2000) Effectiveness Major (for Prevent organ rejection) Burden Not at all hard to take Dosage: 175 mg/kg/day Daily Side effects: depressed mood 0 helpful marks Mar 4, 2012 (Started Mar 06, 2002) Effectiveness Slight (for Prevent [patientslikeme.com]

Additionally, the cyclosporins are researched for their ability to prevent damage to normal functioning cells in autoimmune disorders. Cyclosporin A is over 99% pure and soluble in DMSO and ethyl alcohol. [goldbio.com]