Presentation
In contrast to the common idea that acne vulgaris presents itself only as red bumps or red, inflamed and painful pus-filled pimples, it can actually present itself as whiteheads and blackheads as well. [adult-acne.net]
Presentation [ 4 ] Acne usually presents with a greasy skin with a mixture of comedones, papules and pustules, which present just after puberty and continue for a variable number of years, usually stopping in late teens or early 20s but uncommonly continuing [patient.info]
Hundreds of new and never-before-published images (more than 1,000 photographs in all) clearly depict how skin disorders present at different stages. [books.google.de]
Moderate to severe acne is present in about 20 percent of young people. [bioclarity.com]
Snapshot A 12-year-old boy with no significant past medical history presents with acne to his pediatrician’s office. He has recently started practice for the wrestling team. [medbullets.com]
Entire Body System
- Anemia
[…] keratin and sebum in varying proportions. acne ful´minans a rare form of severe cystic acne seen in teenage boys, characterized by highly inflammatory nodules and plaques that undergo suppurative degeneration leaving ulcerations, fever, weight loss, anemia [medical-dictionary.thefreedictionary.com]
Oliguria Palpitations Cold feet Extreme coldness of the hands and feet Vertigo Weakness and numbness of lower back and legs during pregnancy or postpartum Mal position of the fetus Dysmenorrhea Irregular menstruation Right upper quadrant pain Hepatomegaly Anemia [americandragon.com]
[…] dapsone was minimally more effective than placebo in reducing inflammatory and noninflammatory lesions, but it has never been compared with other topical agents. 10 Unlike oral dapsone, there is no evidence that the topical formulation causes hemolytic anemia [aafp.org]
Eyes
- Excessive Tearing
Rosacea on the other hand, can lead to eye problems such as dryness and excessive tear production. There are reports that your eyes can develop a gritty feeling, which sounds like nonsense but you’ll probably understand it if you have it. [supernaturalacnetreatment.com]
Skin
- Acneiform Eruption
Some drugs and chemicals (eg, corticosteroids, lithium, phenytoin, isoniazid ) worsen acne or cause acneiform eruptions. Symptoms and Signs Skin lesions and scarring can be a source of significant emotional distress. [msdmanuals.com]
A status report on drug-associated acne and acneiform eruptions. J Drugs Dermatol. 2010 Jun. 9(6):627-36. [Medline]. Mango D, Ricci S, Manna P, Miggiano GA, Serra GB. [emedicine.medscape.com]
Psychiatrical
- Social Isolation
Complications [ 2 ] Acne causes a significant psychological and social morbidity, with anxiety, severe depression and suicidal ideation. [ 17 ] There can be a serious lack of self-esteem leading to social isolation. [patient.info]
- Fidgeting
[…] chills Fullness in the chest and hypochondrium (with or without pain) Bitter taste in mouth Nausea Continuous vomiting Hard focal distension in the epigastrium Fullness and pain in the epigastrium Burning diarrhea or no bowel movement Despondency Slight fidgeting [americandragon.com]
Neurologic
- Irritability
Treatments have no significant adverse effects other than drying and irritation (and rare allergic reactions to benzoyl peroxide ). [msdmanuals.com]
Avoid exposure to strong sunlight, which causes irritation that is greatest after a few weeks of treatment. The irritation can be treated with moisturisers. Adapalene is the least irritant. [patient.info]
Gel formulations are claimed to be more effective than creams or lotions, but they are also more irritant. Treatment is usually started with a 2.5% or 5% preparation applied once daily on alternate days. [apps.who.int]
The UV rays can make your skin more sensitive and may lead to skin irritations or redness. If using any of these essential oils causes skin irritation, discontinue use of that oil. [draxe.com]
Make sure there are no irritants like menthol or alcohol that will boost your redness and inflammation. Exfoliate 1-2 times each day using a salicylic acid based exfoliant. [howtogetridofacnescar.com]
- Agitation
Clinical Manifestations Small, light red papules spread diffusely Often primarily on the forehead Flushed, red face, especially in the afternoon or early evening Dry skin Dry lips A thin body Possible premenstrual acne in females A tendency to vexation and agitation [americandragon.com]
Workup
See Workup for more detail. Management Treatment of acne vulgaris should be directed toward the known pathogenic factors, including follicular hyperproliferation, excess sebum, C acnes (formerly P acnes ), and inflammation. [emedicine.medscape.com]
Microbiology
- Staphylococcus Aureus
Many factors have been attributed to the cause of this problem most commonly: bacterial [ 2 ] like staphylococcus aureus and Pseudomonas; fungal like dermtophytic and pityrosporum folliculitis [ 3 ] and viral like mulloscum contangiosum and herpes simplex [omicsonline.org]
Antibiotics, Acne, and Staphylococcus aureus Colonization. Arch Dermatol. 2011 Aug. 147(8):917-21. [Medline]. Bottomley WW, Cunliffe WJ. Oral trimethoprim as a third-line antibiotic in the management of acne vulgaris. [emedicine.medscape.com]
Treatment
Benzoyl peroxide Benzoyl peroxide is a treatment available to people with acne of any severity. It is also a treatment option for people with severe acne who are awaiting specialist treatment. [medicalnewstoday.com]
Though this form of treatment may take several months to see improvement, it will be effective as long as the pills are taken. Accutane. Isotretinoin, or Accutane, is the most effective treatment for severe cystic acne. [grandrivermedicalgroup.com]
Treatment of Cystic Acne The most traditional treatment of cystic acne involves the use of prescription medications. [acnetreatment.net]
Systemic treatment may be combined with topical treatment. People with dark skin often need early systemic treatment because they can develop severe post-inflammatory pigmentation. [patient.info]
So try not to get too disheartened and discouraged if at first your treatment remedy doesn't work: Common Treatment #1: Oral antibiotics Common Treatment #2: Oral contraceptives - for women Common Treatment #3: Accutane (isotretinoin) Common Treatment [realtruthbook.com]
Prognosis
Prognosis of Cystic Acne Cystic acne is believed to affect as many as 40 million people in the United States—about 14% of the current population. [acnetreatment.net]
[…] sebum from comedones into dermis secretion of proinflammatory cells by Propionibacterium acnes ↑ androgen production also plays a role in acne formation Associated conditions polycystic ovary syndrome Cushing syndrome congenital adrenal hyperplasia Prognosis [medbullets.com]
Intra-articular corticosteroid therapy, methotrexate, colchicine cystic acne Mutilating acne Dermatology A form of acne vulgaris which may affect teenagers, 2º to bacterial infection of clogged sebaceous ducts deep in the skin Management Antibiotics, isotretinoin Prognosis [medical-dictionary.thefreedictionary.com]
Five percent of women still have acne at age 45 years. [26] The overall prognosis for patients with acne is good. Patient Education Patients should be instructed on their morning and evening treatment programs. [emedicine.medscape.com]
Etiology
[…] papules) and possibly scarring Typically affects skin with densest sebaceous follicles: face, upper chest, back; uncommon in scalp for unknown reasons Terminology Acne vulgaris is common acne, typically with comedones Acne rosacea is a different disorder Etiology [pathologyoutlines.com]
In the future, I may write another post in which I take a more comprehensive look at the etiology of acne vulgaris, if I feel that’s something people are interested in reading about. [darwinian-medicine.com]
[…] of teenagers but can affect adults as well more severe around puberty location face, back, neck, chest, and upper arms risk factors menstrual cycle emotional stress occlusion of skin with greasy products excessive sweating pregnancy milk consumption Etiology [medbullets.com]
This study for the first time showed this close association between these two conditions and unfortunately there is no record in medical literatures demonstrating this marked connection and elucidating the etiology of the diseases that could be related [omicsonline.org]
SGLT2 inhibitors prevent HF hospitalization regardless of baseline LVEF May 9, 2019 Bruce Jancin Bruce Jancin May 9, 2019 Journal of Clinical Outcomes Management More Quizzes MDIQ Smoking, cardiovascular risk, and diabetes Obesity and cancer incidence Etiologies [jcomjournal.com]
Epidemiology
Epidemiologic analysis was made using t-student, Pearson e Rho di Spearman tests by software SPSS. [research.unipd.it]
Epidemiology of acne vulgaris K. BhateH. [semanticscholar.org]
Bhate K, Williams HC ; Epidemiology of acne vulgaris. Br J Dermatol. 2013 Mar168(3):474-85. doi: 10.1111/bjd.12149. [patient.info]
Introduction Clinical definition common chronic skin condition characterized by inflammatory and non-inflammatory lesions Epidemiology incidence very common demographics up to 85% of teenagers but can affect adults as well more severe around puberty location [medbullets.com]
Dehydroepiandrosterone Sulfate, and Dihydrotestosterone and Acne Lesion Counts in Adult Women, Arch Dermatol. 2005;141(3):333-338. doi:10.1001/archpedi.161.4.356 https://jamanetwork.com/journals/jamadermatology/fullarticle/393279 (5) A H Wu, M C Yu, C-C Tseng & M C Pike Epidemiology [beaute-pure.com]
Pathophysiology
[…] nodulo-cystic acne vulgaris Member Rated 2 Patient case no. 10957 Date added 05 April 2011 Patient details Age Adult Location Saudi Arabia Localisation Head / face Description Primary Lesions Comedones Cystic nodule nodules,cysts,pustules,commedones andscars Pathophysiology [dermquest.com]
Degitz K, Placzek M, Borelli C, Plewig G (2007) Pathophysiology of acne. J Dtsch Dermatol Ges 5: 316-323. Marynick SP, Chakmakijan ZH, McCafree DL (1987) Androgen excess in cystic acne. N Engl J Med308: 981-986. [omicsonline.org]
Pathophysiology The pathogenesis of acne vulgaris is multifactorial. [emedicine.medscape.com]
A smaller percentage will seek medical advice. 8% of adults aged 25 to 34 years; 3% at 35 to 44 years African Americans 37%, Caucasians 24% Etiology and Pathophysiology Androgens ( testosterone and dehydroepiandrosterone sulfate [DHEA-S]) stimulate sebum [unboundmedicine.com]
Pathophysiology of Acne At least four factors are important in the development of acne: plugging of the hair follicle with abnormally cohesive desquamated cells, sebaceous gland hyperactivity, proliferation of bacteria (especially Propionibacterium acnes [aafp.org]
Prevention
[…] scarring topical antibiotics: clindamycin and erythromycin benzoyl peroxide gels (2%, 5%, or 10%) topical retinoids: retinoic acid, adapalene, tazarotene add oral antibiotics: minocycline and doxycycline oral retinoid: isotretinoin (prevent scarring) [quizlet.com]
Getting into the habit of keeping those fingers and hands off the face will help prevent bacteria from settling on the complexion. [acneaseeu.com]
Drug treatment can be effective at preventing cysts and scarring. Mild or moderate acne can be managed with the help of a doctor. [medicalnewstoday.com]
Once you’re clear on the type of acne you are experiencing, you can work on a plan to treat, reduce, and possibly even prevent it. [thedermreview.com]