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Cystic Acne Vulgaris


Presentation

  • Presentation [ 4 ] Acne usually presents with a greasy skin with a mixture of comedones, papules and pustules, which present just after puberty and continue for a variable number of years, usually stopping in late teens or early 20s but uncommonly continuing[patient.info]
  • Moderate to severe acne is present in about 20 percent of young people.[bioclarity.com]
  • It presents somewhat differently in people with dark skin”. Cystic Acne Breakouts Affecting the facial skin, chest area, back, shoulder area and, at times, upper arms.[treatmentsforcysticacne.net]
  • Retained sebum inside the gland and growth of propinibacterium acne, an anaerobic dipththrtrois normally present within pilo-sebaseous duct sets in complement mediated inflammation so that the blackhead turns to a vesicle and pustule.[medvin2u.net]
  • In contrast to the common idea that acne vulgaris presents itself only as red bumps or red, inflamed and painful pus-filled pimples, it can actually present itself as whiteheads and blackheads as well.[adult-acne.net]
Rigor
  • The truth is, rubbing or scrubbing your skin too rigorous or washing with harsh cleansers, soaps or chemical compounds actually will irritate your skin and will make acne even worse.[treatmentsforcysticacne.net]
  • As a way to avoid rigorous forms of cyst, skin must be properly taken care. If proper care and medication is not provided, permanent and deep scarring may take place . Generally, scars can not be removed entirely without traces.[howtogetridofacnescar.com]
Dry Eyes
  • Dry eyes and lips and nose bleed may occur. Pseudotumor cerebri syndrome, bony hyperostosis and hair loss may occur but the agent is certainly not stored in liver.[medvin2u.net]
  • Minor side effects include dry mouth and dry eyes. Another agent used against acne is tretinoin (all- trans -retinoic acid), which is applied topically to reduce the number of comedones and to prevent formation of inflammatory lesions.[medical-dictionary.thefreedictionary.com]
  • eyes, chapped lips, drying of mucous membranes Pain or stiffness of large joints and lower back with high dosages Associated with depression, suicidal thoughts, attempted suicide, and (rarely) completed suicide Unclear whether associated with new or[msdmanuals.com]
  • However, it often induces signs of chronic hypervitaminosis A, including cheilitis, dry eyes, generalized xerosis, pruritus and paronychia, and, most problematic of all, it is a proven and potent human teratogen.[apps.who.int]
Osteophyte
  • Bilateral 2.5 and 3.0 mm nasal bone osteophytes developed five weeks following the initiation of oral isotretinoin therapy (50 mg daily) for severe cystic acne vulgaris in a healthy 30-year-old white woman who had undergone uneventful rhinoplasty 12 years[ncbi.nlm.nih.gov]
  • Long-term retinoid therapy may be complicated by skeletal changes, including osteoporosis and osteophyte formation. However, no studies have reported notable bony changes associated with short-term isotretinoin therapy for the treatment of acne.[aafp.org]
Fracture
  • Both cysts nodules start out as deep fractures that result with infection setting in around the pore wall of your skin.[realtruthbook.com]
Acneiform Eruption
  • Some drugs and chemicals (eg, corticosteroids, lithium, phenytoin, isoniazid ) worsen acne or cause acneiform eruptions. Symptoms and Signs Skin lesions and scarring can be a source of significant emotional distress.[msdmanuals.com]
Epistaxis
  • […] acupuncture : Endocrine, Subcortex, Sympathetic, Lung, Shenmen Clinical Manifestations Papular whiteheads and blackheads Most common around the mouth, chest and upper back The face is prone to oiliness Dryness with burning pain in the nose Possible epistaxis[americandragon.com]
Anger
  • IMBALANCE: Pitta AGGRAVATED BY: Anger tension, Anxiety, Stress, Hot weather, Spicy sour foods, Sea foods, Canned or Preserved foods, Pizza, French fries.[herbal-clinic.com]
  • It is not caused or made worse by lack of sleep, constipation, masturbation, venereal disease, or by anger or hostility.[medical-dictionary.thefreedictionary.com]
  • Intestines Herb Formulas Points Clinical Manifestations Abdominal distention and pain Gas Borborygmus Diarrhea Distention and pain in the sides or flanks Suffocating sensation in the chest Tendency to sigh Melancholy Depression Irritability Inappropriate anger[americandragon.com]
Social Isolation
  • Complications [ 2 ] Acne causes a significant psychological and social morbidity, with anxiety, severe depression and suicidal ideation. [ 17 ] There can be a serious lack of self-esteem leading to social isolation.[patient.info]
Social Isolation
  • Complications [ 2 ] Acne causes a significant psychological and social morbidity, with anxiety, severe depression and suicidal ideation. [ 17 ] There can be a serious lack of self-esteem leading to social isolation.[patient.info]

Treatment

  • Though this form of treatment may take several months to see improvement, it will be effective as long as the pills are taken. Accutane. Isotretinoin, or Accutane, is the most effective treatment for severe cystic acne.[grandrivermedicalgroup.com]
  • Treatment of Cystic Acne The most traditional treatment of cystic acne involves the use of prescription medications.[acnetreatment.net]
  • Benzoyl peroxide Benzoyl peroxide is a treatment available to people with acne of any severity. It is also a treatment option for people with severe acne who are awaiting specialist treatment.[medicalnewstoday.com]
  • Systemic treatment may be combined with topical treatment. People with dark skin often need early systemic treatment because they can develop severe post-inflammatory pigmentation.[patient.info]
  • So try not to get too disheartened and discouraged if at first your treatment remedy doesn't work: Common Treatment #1: Oral antibiotics Common Treatment #2: Oral contraceptives - for women Common Treatment #3: Accutane (isotretinoin) Common Treatment[realtruthbook.com]

Prognosis

  • Prognosis of Cystic Acne Cystic acne is believed to affect as many as 40 million people in the United States—about 14% of the current population.[acnetreatment.net]
  • Intra-articular corticosteroid therapy, methotrexate, colchicine cystic acne Mutilating acne Dermatology A form of acne vulgaris which may affect teenagers, 2º to bacterial infection of clogged sebaceous ducts deep in the skin Management Antibiotics, isotretinoin Prognosis[medical-dictionary.thefreedictionary.com]
  • […] of sebum from comedones into dermis secretion of proinflammatory cells by Propionibacterium acnes androgen production also plays a role in acne formation Associated conditions polycystic ovary syndrome Cushing syndrome congenital adrenal hyperplasia Prognosis[medbullets.com]
  • Prognosis Gradual improvement over time (usually within 8 to 12 weeks after beginning therapy) Complications Acne conglobata: severe confluent inflammatory acne with systemic symptoms Facial scarring and psychological distress, including anxiety, depression[unboundmedicine.com]

Etiology

  • […] papules) and possibly scarring Typically affects skin with densest sebaceous follicles: face, upper chest, back; uncommon in scalp for unknown reasons Terminology Acne vulgaris is common acne, typically with comedones Acne rosacea is a different disorder Etiology[pathologyoutlines.com]
  • In the future, I may write another post in which I take a more comprehensive look at the etiology of acne vulgaris, if I feel that’s something people are interested in reading about.[darwinian-medicine.com]
  • […] of teenagers but can affect adults as well more severe around puberty location face, back, neck, chest, and upper arms risk factors menstrual cycle emotional stress occlusion of skin with greasy products excessive sweating pregnancy milk consumption Etiology[medbullets.com]
  • SGLT2 inhibitors prevent HF hospitalization regardless of baseline LVEF May 9, 2019 Bruce Jancin Bruce Jancin May 9, 2019 Journal of Clinical Outcomes Management More Quizzes MDIQ Smoking, cardiovascular risk, and diabetes Obesity and cancer incidence Etiologies[jcomjournal.com]
  • A smaller percentage will seek medical advice. 8% of adults aged 25 to 34 years; 3% at 35 to 44 years African Americans 37%, Caucasians 24% Etiology and Pathophysiology Androgens ( testosterone and dehydroepiandrosterone sulfate [DHEA-S]) stimulate sebum[unboundmedicine.com]

Epidemiology

  • Bhate K, Williams HC ; Epidemiology of acne vulgaris. Br J Dermatol. 2013 Mar168(3):474-85. doi: 10.1111/bjd.12149.[patient.info]
  • Introduction Clinical definition common chronic skin condition characterized by inflammatory and non-inflammatory lesions Epidemiology incidence very common demographics up to 85% of teenagers but can affect adults as well more severe around puberty location[medbullets.com]
  • With rosacea, women ages 20 to 60 are the predominant epidemiological group.[draxe.com]
  • J Am Acad Dermatol. 2016 Nov; 75(5):983-991. 23 Cancer Epidemiology in Older Adolescents & Young Adults.[aad.org]
  • Preadolescent acne 7 to 12 years; common, 47% of children, usually due to adrenal awakening, comedonal lesions Do not use tetracyclines in those 1 ); other therapies similar to adolescent acne Epidemiology Predominant age: early to late puberty, may persist[unboundmedicine.com]
Sex distribution
Age distribution

Pathophysiology

  • A smaller percentage will seek medical advice. 8% of adults aged 25 to 34 years; 3% at 35 to 44 years African Americans 37%, Caucasians 24% Etiology and Pathophysiology Androgens ( testosterone and dehydroepiandrosterone sulfate [DHEA-S]) stimulate sebum[unboundmedicine.com]
  • Pathophysiology of Acne At least four factors are important in the development of acne: plugging of the hair follicle with abnormally cohesive desquamated cells, sebaceous gland hyperactivity, proliferation of bacteria (especially Propionibacterium acnes[aafp.org]

Prevention

  • […] scarring topical antibiotics: clindamycin and erythromycin benzoyl peroxide gels (2%, 5%, or 10%) topical retinoids: retinoic acid, adapalene, tazarotene add oral antibiotics: minocycline and doxycycline oral retinoid: isotretinoin (prevent scarring)[quizlet.com]
  • Getting into the habit of keeping those fingers and hands off the face will help prevent bacteria from settling on the complexion.[acneaseeu.com]
  • Drug treatment can be effective at preventing cysts and scarring. Mild or moderate acne can be managed with the help of a doctor.[medicalnewstoday.com]
  • Once you’re clear on the type of acne you are experiencing, you can work on a plan to treat, reduce, and possibly even prevent it.[thedermreview.com]

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