RESULTS: Twenty-seven RCTs were identified and included in the present systematic review and meta-analysis, involving a total of 7343 patients. [ncbi.nlm.nih.gov]

At present, its role in carcinoid heart disease is unknown. Conference: 7th Annual ENETS Conference (2010) Category: Clinical Presenting Author: Dr. [enets.org]

• Anemia

  In addition, more incidences of grade 3 or 4 anemia, thrombocytopenia, and neurotoxicity were observed in the doublet combination group. [ncbi.nlm.nih.gov]

  Cytoxan can also cause bone marrow suppression, resulting in low red and/or white blood cell counts ( anemia, leukopenia) and low platelets (thrombocytopenia), which can raise the risk of bleeding and infection (especially shingles ). [verywell.com]

  If proper precautions are not observed thiotepa may cause leukopenia, thrombocytopenia and anemia. [rxmed.com]

• Sore Mouth

  Mouth problems The cells which line the mouth are affected by some cytotoxic medicines. This may lead to a sore mouth, a dry mouth or other mouth problems. [patient.info]

Two patients from each group interrupted treatment because of side effects or inefficacy. CONCLUSION: Most nephrotic patients with membranous nephropathy responded to either treatment. [ncbi.nlm.nih.gov]

The overall prognosis for this group of patients is still poor, emphasizing the importance of more effective therapies. Betulinic acid (Bet A) has been described as a novel cytotoxic compound active against melanoma and neuroblastoma cells. [ncbi.nlm.nih.gov]

Pancreatic adenocarcinoma is a highly aggressive cancer with poor prognosis. The majority of patients are diagnosed with advanced-stage disease and have limited treatment options. [roswellpark.org]

[…] clear evidence for the benefit of pulsed intravenous cyclophosphamide over steroids alone in reducing clinical and serological activity of lupus, histological damage, and end stage renal failure. 34 35 Before the routine use of cyclophosphamide, the prognosis [adc.bmj.com]

Polyarteritis Nodosa, has a similar prognosis and benefit to WG when treated with CP and steroids. A similar drug protocol is recommended. Most authors recommend use of prednisone combined with CP for the treatment of PAN. [arthritis.co.za]

[…] is unknown whether this is a function of inadequate or incomplete suppression of immune pathways mediating the abnormality; the influences of pathogenic mechanisms that are unaffected by these drugs; or, perhaps most likely, the failure to eliminate etiologic [annals.org]

Controlled epidemiological surveys suggest that cytotoxic drugs are associated with reproduction toxicology, embryo toxicity and teratogenicity, as well as an increased risk of malignant tumours. [hospitalpharmacyeurope.com]

They also address the consequences of drug interactions and the basic pathophysiology of central nervous system toxicity. [books.google.ro]

In addition, drug combinations have been advocated on the premise that synergisms might result from disruptions of separate pathophysiologic pathways involved in synovitis. [annals.org]

Fourth, the proportion of IL-4–positive T cells was greater in patients with progressive disease, compared with stable patients, suggesting that IL-4 played pathophysiologic roles in suppressing cell death. 15 Finally, CLL cells within lymph nodes and [bloodjournal.org]

In this regard, here we assessed whether a cancer preventive agent silibinin synergizes the therapeutic potential of doxorubicin (Dox), cisplatin or carboplatin, the chemotherapeutic drugs, in both estrogen-dependent and -independent human breast carcinoma [ncbi.nlm.nih.gov]

Negative pressure rooms that prevent any spilled medication from leaving the room are also recommended. 2. [cupe.ca]

Useful in prevention of recurrence after condyloma ablation if started within 4 wk, especially in immunocompromised patients. [emedicine.medscape.com]