The patients presented with visual hallucinations, disorientation, incomprehensible and nonsensical speech, and dilated sluggish pupils. [ncbi.nlm.nih.gov]

Mass spectral data on urine extracts of a 20-year-old male showed the molecular ions and principal fragment ions of scopolamine and atropine, present in Datura stramonium. [astm.org]

We present the case of two children admitted at the Children Emergency Room of a teaching hospital following ingestion of extract of Datura stramonium. [njcponline.com]

• Fever

  We describe the case of a boy who had slurred speech, fever, hallucinations, tachycardia, dilated pupi… Poisoned after Dinner: Dolma with Datura Stramonium. [unboundmedicine.com]

  Fever : Jimson weed might make fever worse. Stomach ulcer : Jimson weed might delay stomach emptying and make ulcers worse. Stomach and intestinal infections : Jimson weed might slow down the emptying of the stomach and intestines. [webmd.com]

  Symptoms of poisoning in humans and livestock include restlessness, irritability, depression, dilated pupils, delirium, impaired vision, constipation, fever, extreme thirst, and convulsions. [kswildflower.org]

  Haug Browse recently published Learning/CME Learning/CME View all learning/CME CME Case 3-2019: A 70-Year-Old Woman with Fever, Headache, and Progressive Encephalopathy Caplacizumab Treatment for Acquired Thrombotic Thrombocytopenic Purpura Randomized [nejm.org]

  Jimsonweed poisoning causes dry mucous membranes and skin, thirst, flushing, fever, blurred vision, altered mental status, mydriasis, urinary retention, tachycardia, coma, and, in rare cases, death ( 1 ,4 ). [cdc.gov]

• Gastric Lavage

  In addition, gastric lavage was done. About 19 hours after admission, he became fully conscious, cooperative, and communicating intelligently. He was also able to recognize familiar people. [njcponline.com]

  Gastric lavage and activated charcoal administration were performed. The child was intubated and mechanically ventilated until consciousness improvement. [pubmed.ncbi.nlm.nih.gov]

  Salen P, Shih R, Sierzenski P, Reed J (2003) Effect of physostigmine and gastric lavage in a Datura stramonium-induced anticholinergic poisoning epidemic. Am J Emerg Med 21:316–317 PubMed Article Google Scholar 6. [link.springer.com]

  Intoxication was not thought in the hospital where the patient was first admitted and gastric lavage and active coal were not administered because 12 hours passed before she was admitted to our hospital. [dusunenadamdergisi.org]

• Nausea

  It is poisonous and can cause many toxic effects including dry mouth and extreme thirst, vision problems, nausea and vomiting, fast heart rate, hallucinations, high temperature, seizures, confusion, loss of consciousness, breathing problems, and death [webmd.com]

  […] however, restricted within the following countries: Australia: Datura is a Schedule I poison in Australia [ citation needed ], but scopolamine is Schedule 4 (Prescription only) and it is in over the counter drugs (Buscopan) to treat symptoms such as nausea [psychonautwiki.org]

• Decreased Bowel Sounds

  Typical symptoms of DS intoxication are those of atropine intoxication, which are dry skin and mucosa, flushing, mydriasis, sinus tachycardia, hyperpyrexia, decreased bowel sounds, urinary retention, and neurological disorders with ataxia, impaired short-term [intjem.springeropen.com]

  bowel sounds, urinary retention, and neurological disorders with ataxia, impaired short-term memory, disorientation, confusion, hallucinations (visual and auditory), psychosis, agitated delirium, seizures, and coma. [cjhr.org]

• Abdominal Pain

  Abdominal pain Abdominal pain may have many underlying causes. Some of these causes include gall bladder stone and kidney stone. In these conditions, datura and medicines containing datura are used to alleviate the pain. [ayurtimes.com]

• Tachycardia

  The patient presented with a typical anticholinergic syndrome (dryness of mouth, mydriasis, flushing, tachycardia, agitation, hallucinations) and was treated with symptomatic and supportive measures. [ncbi.nlm.nih.gov]

  During the next 6 hours in the emergency department, the six patients continued to experience tachycardia, mydriasis, and altered mental status. One remained unconscious. [cdc.gov]

  Repeated neurological examination revealed a gradual improvement of her state of consciousness with disappearance of tachycardia, mydriasis, delirium, and agitation. [intjem.springeropen.com]

  Blockade of visceral muscarinic receptors produces the following effects 1 Heart -diminished vagal tone at the SA node causes relative tachycardia 2 Blood vessels- vasoconstriction via muscarinic receptor blockade in endothelial cells results in decreased [usmle1-topscorer.blogspot.com]

  Tachycardia usually responds to crystalloids. [11] In severe cases, physostigmine, a cholinesterase inhibitor, should be used to reverse anticholinergic toxicity. [cjhr.org]

• Hypertension

  [Hypertensive crisis and anticholinergic toxidrome secondary to accidental consumption of datura stramonium in two children]. Batouche DD, Benatta NF, Tabeliouna K, Boudjahfa S, Touhami Y, Hakkoum S. Batouche DD, et al. [pubmed.ncbi.nlm.nih.gov]

  He had tachycardia with pulse rate of 132 beats per minute and systolic hypertension with blood pressure of 150/55 mmHg. There were no focal neurological signs and other systemic examination findings were normal. [njcponline.com]

  […] cardiovascular disease, gangrene, asthma, glaucoma, and GI/GU obstruction.(2,7,10) Thus its use as a cholinergic agent in Jimson Weed poisoning is controversial and is generally reserved for life-threatening, intractable, anticholinergic effects including hypertension [erowid.org]

• Weak Pulse

  pulse, convulsions, and coma Toxic Principle: Tropane alkaloids Severity: Toxic only if large quantities are eaten. [plants.ces.ncsu.edu]

• Flushing

  The patient presented with a typical anticholinergic syndrome (dryness of mouth, mydriasis, flushing, tachycardia, agitation, hallucinations) and was treated with symptomatic and supportive measures. [ncbi.nlm.nih.gov]

  After 6 hours of admission, child developed irrelevant speech, excitation, delirium, hallucinations, and flushing of face. He was agitated and aggressive with purposeless movements. Child had not passed urine for last 8 hours. [cjhr.org]

  […] tone at the SA node causes relative tachycardia 2 Blood vessels- vasoconstriction via muscarinic receptor blockade in endothelial cells results in decreased nitric oxide synthesis In spite of this effect, atropine poisoning is associated with cutaneous flushing [usmle1-topscorer.blogspot.com]

  Facial and truncal skin was normal, and flushing was not detected. She had a Glasgow Coma Scale score of 11/15. [intjem.springeropen.com]

  […] lavender purple Hardiness: frost sensitive Exposure: full sun Family: Solanaceae Origin: North America Distribution: Naturalized and weedy, cultivated Poison Part: All parts, mainly seeds and leaves Poison Delivery Mode: Ingestion Symptoms: Hot, dry, and flushed [plants.ces.ncsu.edu]

• Blurred Vision

  Written testimonials for Datura on the Erowid Web site, under titles like “Truly the Devil’s Weed,” “Nightmares in Flux” and “This is Madness,” include delusions of phantom cigarettes, conversations with imaginary friends, amnesia, blurred vision, a desire [cityroom.blogs.nytimes.com]

  This results in blurred vision. There are also dry mouth with dysphagia and dysphonia, tachycardia and urinary retention. The skin may be flushed and dry accompanied by hyperthermia. [globinmed.com]

  Blurred vision, palpitation, urinary retention, dry mouth, ileus, flushing, dysrhytmia, auditory and visual hallucinations and convulsions can be seen after its use (5). [dusunenadamdergisi.org]

  These would include incoherent speech, impaired coordination, rapid heart beat, dilated pupils, blurred vision and dry, flushed or hot skin. In extreme cases users can experience seizures, intense visual or auditory hallucination, or cardiac arrest. [aacc.org]

  Jimsonweed poisoning causes dry mucous membranes and skin, thirst, flushing, fever, blurred vision, altered mental status, mydriasis, urinary retention, tachycardia, coma, and, in rare cases, death ( 1 ,4 ). [cdc.gov]

• Photophobia

  […] an anticholinergic delirium: a complete inability to differentiate reality from fantasy (frank delirium, as contrasted to hallucination); hyperthermia; tachycardia; bizarre, and possibly violent behavior; and severe mydriasis with resultant painful photophobia [link.springer.com]

  […] complete inability to differentiate reality from fantasy (delirium, as contrasted to hallucination); hyperthermia; tachycardia (increased heart-rate); bizarre, and possibly violent behavior; and severe mydriasis (pupil dilation) with resultant painful photophobia [sabotagetimes.com]

• Dry Eyes

  eyes), salivation (dry mouth) and sweating (dry and hot skin) Atropine decreases one's ability to sweat, contributing to hyperthermia 7 Eye- mydriasis (dilated pupils) and cycloplegia (inability to focus on the near objects, blurry vision) 8 CNS -hallucinations [usmle1-topscorer.blogspot.com]

• Agitation

  Repeated neurological examination revealed a gradual improvement of her state of consciousness with disappearance of tachycardia, mydriasis, delirium, and agitation. [intjem.springeropen.com]

  The patient presented with a typical anticholinergic syndrome (dryness of mouth, mydriasis, flushing, tachycardia, agitation, hallucinations) and was treated with symptomatic and supportive measures. [ncbi.nlm.nih.gov]

  If patient is severely agitated then benzodiazepines can be used for sedation (6). [dusunenadamdergisi.org]

• Seizure

  Jimson weed intoxication should be considered in cases of patients presenting with unexplained peripheral and central anticholinergic symptoms including delirium, agitation and seizures, especially among younger patients and partygoers. [ncbi.nlm.nih.gov]

  Among the serious neurologic and medical complications are coma, trauma, infection, seizures, stroke, altered mentation, peripheral neuropathies, myelopathies, Parkinsonism, visual disturbances, dyskinesias, cerebellar ataxia, impotence, and fetal effects [books.google.com]

  Seizures : Jimson weed can cause seizures. Do not use jimson weed if you suffer from frequent seizures. [webmd.com]

  Phenothiazines for agitated delirium should be avoided due to their anticholinergic properties, and barbiturates can be administered in the case of seizures refractory to benzodiazepines [ 1, 10 ]. [intjem.springeropen.com]

  Signs and symptoms such as mydriasis, tachycardia, arrhythmias, agitation, seizures and coma can appear.Diagnosis is clinical and early treatment should be given, including gastrointestinal decontamination, supportive care and physostigmine in life-threatening [analesdepediatria.org]

• Confusion

  They developed neurotoxicity (confusion, agitation, mydriasis, and hallucination) and were managed symptomatically with good outcome. [ncbi.nlm.nih.gov]

  They developed neurotoxicity (confusion, agitation, mydriasis, and hallucination) and were managed symptomatically with… CONTINUE READING Highly Cited This paper has 23 citations. REVIEW CITATIONS From This Paper Topics from this paper. [semanticscholar.org]

  The others demonstrated confusion, aggression, agitation, disorganized speech, incoherence, and hallucinations. All six were admitted to the hospital, five to the intensive-care unit. [cdc.gov]

  As many psychiatric symptoms and signs such as bizarre behaviors, hallucinations and agitation can be observed in the patient, delirium can often be confused with other psychiatric disorders (2,3). [dusunenadamdergisi.org]

• Headache

  The less alarming sequelae are myriad (fatigue, loss of appetite, headaches, dizziness, etc.). Dr. Brust has written the most comprehensive source available to the point of being encyclpedic, including references. [books.google.com]

  full sun Family: Solanaceae Origin: North America Distribution: Naturalized and weedy, cultivated Poison Part: All parts, mainly seeds and leaves Poison Delivery Mode: Ingestion Symptoms: Hot, dry, and flushed skin, hallucinations, pupil dilation, headache [plants.ces.ncsu.edu]

  Haug Browse recently published Learning/CME Learning/CME View all learning/CME CME Case 3-2019: A 70-Year-Old Woman with Fever, Headache, and Progressive Encephalopathy Caplacizumab Treatment for Acquired Thrombotic Thrombocytopenic Purpura Randomized [nejm.org]

  Symptoms associated with D. metel poisoning include flushed skin, headaches, hallucinations, and possibly convulsions or even a coma. [keys.lucidcentral.org]

• Dizziness

  The less alarming sequelae are myriad (fatigue, loss of appetite, headaches, dizziness, etc.). Dr. Brust has written the most comprehensive source available to the point of being encyclpedic, including references. [books.google.com]

  All patients reported thirst, hallucinations, and dizziness when first examined by emergency medical technicians; however, after arrival at the hospital, the clinical course for the six patients diverged. [cdc.gov]

  Two were unconscious and the others were laughing, confused, dizzy, thirsty and suffering hallucinations. [thepoisongarden.co.uk]

Conservative treatment of Jimson weed ingestion. Vet Hum Toxicol, 35 (1993), pp. 32-33 [13.] S.R. Guharoy, M. Barajas. Atropine intoxication from the ingestion and smoking of Jimson weed. Vet Hum Toxicol, 33 (1991), pp. 588-589 [14.] J.F. [analesdepediatria.org]

The treatment of choice for anticholinergic poisoning is mainly supportive care and gastrointestinal decontamination with activated charcoal. [ncbi.nlm.nih.gov]

Although physostigmine is the antidote for anticholinergic toxicity, its use is controversial despite recent reports of it being a safe treatment. [intjem.springeropen.com]

Monitoring and supportive treatment were administered. Treatment of anticholinergic intoxication is mainly supportive and its specific antidote is physostigmine. [dusunenadamdergisi.org]

Please find relevant information on First Aid for Datura Stramonium Poisoning regarding cause, signs & symptoms, administration of first aid treatment, prognosis, preventive measures, and additional resources HERE. [dovemed.com]

Prognosis is usually favorable. Key words: Datura Poisoning Anticholinergic syndrome Hallucinations El Texto completo está disponible en PDF Bibliografía [1.] B.T. Vanderhoff, K.H. Mosser. [analesdepediatria.org]

Please find relevant information on First Aid for Datura Stramonium Poisoning regarding cause, signs & symptoms, administration of first aid treatment, prognosis, preventive measures, and additional resources HERE. [dovemed.com]

The prognosis of DS intoxication is usually favorable, as in our case, but it may be fatal, especially during massive intoxications meant to be autolytic or the result of toxicomania [ 6 ]. [intjem.springeropen.com]

[…] seriously ill from intentionally ingesting datura. [6] [7] There are also several reports in the medical literature of deaths from D. stramonium and D. ferox intoxication. [8] [9] [10] Children are especially vulnerable to atropine poisoning and their prognosis [psychonautwiki.org]

Delirium is a complicated condition due to variable symptoms, signs and clinical courses and presence of several risk and etiological factors and advanced age is considered as an important predisposing factor. [dusunenadamdergisi.org]

Epidemiology Frequency United States Incidence is sporadic, with clusters of poisoning cases, mostly among adolescents using plants for their hallucinogenic effects. [emedicine.medscape.com]

Epidemiology and Social History - The plant has been described throughout history as a toxin famous for its mind altering properties. There are references to it in Homer's Odyssey and Shakespeare plays. [aacc.org]

EPIDEMIOLOGY The plant has been described throughout history as a toxin famous for its mind-altering properties. [erowid.org]

Pathophysiology Toxicity from plants containing tropane alkaloids manifests as classic anticholinergic poisoning. [emedicine.medscape.com]

The best form of invasive species management is prevention. If prevention is no longer possible, it is best to treat the weed infestations when they are small to prevent them from establishing (early detection and rapid response). [keys.lucidcentral.org]

From the Centers for Disease Control and Prevention. Jimson weed poisoning-Texas, New York, and California, 1994. MMWR 1995; 44: 41-44 [8.] D.L. Savitt, J.R. Roberts, E.G. Siegel. Anisocoria from Jimson weed. Jama, 255 (1986), pp. 1439-1440 [9.] M. [analesdepediatria.org]

Adolescents must have access to correct and detailed information on poisoning prevention since this remains one of the effective interventions in solving health and social challenges facing them. [njcponline.com]

Please find relevant information on First Aid for Datura Stramonium Poisoning regarding cause, signs & symptoms, administration of first aid treatment, prognosis, preventive measures, and additional resources HERE. [dovemed.com]

PREVENTION Defoliation programs are one way to decrease access to Jimson Weed. It is important to educate health care providers about the hazards and symptoms involved with contact with Datura stramonium. [erowid.org]