Edit concept Question Editor Create issue ticket

Decreased Diffusion Capacity of the Lung

Diffusion Capacity of Lung (dl) Decreased


  • That diagram again: The college presents the candidates with a series of lung function variables, as well as actual and predicted values.[derangedphysiology.com]
  • The mean values of age and height from the present study were substituted in the formulas of previous studies in calculating the predicted mean. The observed means are those that were calculated from the total sample of the present study.[kjim.org]
  • In the setting of a normal chest radiograph, early ILD or pulmonary vascular disease or both can be present. This observation underscores the need for chest CT for confirming the diagnosis of ILD.[consultant360.com]
  • Data are presented as median (interquartile range). Results. Patients with severe asthma compared with those with nonsevere disease had lower VC, pre- and postbronhodilator FVC, pre- and postbronhodilator FEV 1.[erj.ersjournals.com]
  • METHODS: Asymptomatic patients with SLE and/or APS who were found to have a low DLCO in the previous study were contacted.[ncbi.nlm.nih.gov]
  • Methods Asymptomatic patients with SLE and /or APS who were found to have a low DLCO in the previous study were contacted.[acrabstracts.org]
  • Patients with methemoglobinemia most often have asymptomatic cyanosis. In severe cases, oxygen delivery is reduced to such a degree that symptoms of tissue hypoxia, such as confusion, angina, and myalgias, result.[msdmanuals.com]
  • Maybe the emphysema is almost asymptomatic but it's still hard to know. I will protect my airway & lungs more than I ever have but as an adult, I always have. Stuff has always bothered me before it bothers others in my household.[mdjunction.com]
  • Monitoring of children with diseases that cause pulmonary bleeding In primary pulmonary haemosiderosis, Goodpasture syndrome and granulomatosis with polyangiitis, an increase in diffusing capacity can predict relapse or indicate progression in asymptomatic[analesdepediatria.org]
Weight Loss
  • The diagnosis should be suspected in a patient taking amiodarone with nonproductive cough, dyspnea, and weight loss accompanied by an abnormal chest radiographs demonstrating chronic interstitial lung changes.[consultant360.com]
  • How the reduction in Dlco is interpreted can influence clinical decisions in patients with unexplained dyspnea or dyspnea that fails to improve with initial treatments such as bronchodilators. Variability in how Dlco is reported is a concern.[consultant360.com]
  • First, a question: A 62 year old woman with COPD is evaluated for chronic dyspnea. She has long history of smoking. Respiratory rate is 30; pulse 102; the patient is afebrile.[rostovreview.wordpress.com]
  • Page 4/5 Diagnosis Bronchial asthma Dyspnea Rest: Yes Dyspnea Exercise: Yes Cough No Persistent: No Procuctive (cc) ____ Smoker: No Cigarettes: No Pipe: No How Long: ___ Quit: No Stopped: ____ Spirometry FVC Liters Ref 3.31 Pre 2.37 % Ref 72 Post 2.38[mdjunction.com]
  • Respiratory complaints may be under-reported and/or unrecognized in RA patients with lung disease as individuals with RA are generally less physically active due to joint pain and chronic fatigue and thus less likely to experience symptoms such as dyspnea[hopkinsarthritis.org]
  • One girl developed idiopathic pneumonia syndrome 6 weeks after BMT with marked dyspnea, cough, and fever. Corticosteroid therapy had a prompt effect on the symptoms.[nature.com]
Pulmonary Disorder
  • Restrictive pulmonary disorders can be caused by a pulmonary disease such as interstitial pulmonary fibrosis or a non-pulmonary disease such as rigidity of the chest wall, paralysis or muscle weakness.[iaff.org]
  • Conclusion: The multiple inert gas technique has confirmed that the major problems in pulmonary disorders are not true shunts, diffusion barriers, and lamination of alveolar gasses, but dominantly ventilation/perfusion inequality with functional veno-arterial[zuniv.net]
  • Patients with methemoglobinemia most often have asymptomatic cyanosis. In severe cases, oxygen delivery is reduced to such a degree that symptoms of tissue hypoxia, such as confusion, angina, and myalgias, result.[msdmanuals.com]
  • The patient is severely dyspnoeic, with tachypnoea, tachycardia, and coughing up a frothy pink sputum containing red cells. There is basal crepitation by auscultation and often whistling rhonchi.[zuniv.net]
  • A decreased FEV1 may mean either an obstructive pattern of lung disease, or a diminished expiratory effort (eg. in a patient who has some sort of myopathy or neuropathy).[derangedphysiology.com]
  • Dlco can be normal or slightly decreased in extrinsic restrictive disorders (underlying lung physiology is normal except for atelectasis) such as Guillain-Barré syndrome, myasthenia gravis, amyotrophic lateral sclerosis, and corticosteroid-induced myopathy[consultant360.com]
  • […] interlaboratory variability, 15 much greater than with other pulmonary function measurements, and standardisation is therefore essential. 2,8,16,17 Reference values have been established in healthy white children aged from 5 to 19 for DLCO and VA. 18 We must not forget[analesdepediatria.org]


  • Hypocapnia is P co 2 35 mm Hg.[msdmanuals.com]
  • Hypocapnia, 2. Acute hypercapnia and 3. Vascular lung disorders. - Hypoxia is described in Chapter 15. 1. Hypocapnia Hypocapnia or hyperventilation is a disorder with abnormally reduced P aCO2 .[zuniv.net]
  • With gross hypoxia of rapid onset hypocapnia depresses respiration, but compensation occurs over about six days. After years of chronic hypoxia, hypoxic drive becomes markedly attenuated.[anaesthetist.com]
Lung Function Testing Abnormal
  • function testing abnormal ICD-10-CM R94.2 is grouped within Diagnostic Related Group(s) (MS-DRG v 36.0): 205 Other respiratory system diagnoses with mcc 206 Other respiratory system diagnoses without mcc Convert R94.2 to ICD-9-CM Code History 2016 (effective[icd10data.com]


  • PATIENTS: Thirteen patients without any initial pulmonary pathology who developed the mentioned pulmonary pathology due to bleomycin treatment. INTERVENTIONS: Bleomycin treatment.[repub.eur.nl]
  • These include: Diagnostic: Doctors may use DLCO to diagnose medical conditions such as emphysema, Treatment monitoring: Diffusing capacity may be monitored to determine whether a condition has worsened, or if it has improved with treatment.[verywell.com]
  • Also, if you’re undergoing treatment for lung disease, your doctor may order this test from time to time to monitor the disease’s progress and how well your treatment is working.[healthline.com]
  • [Randomized Controlled Trial] SV Sarcoidosis Vasc Diffuse Lung Dis 2015 Jun 22; 32(1):37-42 Skaria SD, Yang J, … Smaldone GC CONCLUSIONS: DLCO was significantly improved following inhaled (IFN-γ) as treatment for IPF.[unboundmedicine.com]
  • It has been suggested that early diagnosis and treatment with antifibrotic agents may alter the prognosis of pulmonary fibrosis (18, 19).[hopkinsarthritis.org]


  • Studies have confirmed that patients with fewer symptoms of shortness of breath generally have a better prognosis. This is not to say that you can affect your prognosis by being in denial about your breathing symptoms.[pulmonaryfibrosismd.com]
  • Factors affected by DLCO Decrease A DLCO of less than 60% predicted portends a poor prognosis for lung cancer resection. FEV1 is of lesser prognostic value for lung resection survival.[chestandsleepcenter.com]
  • It has been suggested that early diagnosis and treatment with antifibrotic agents may alter the prognosis of pulmonary fibrosis (18, 19).[hopkinsarthritis.org]
  • (eg, a severely decreased Dlco in nonspecific interstitial pneumonitis and idiopathic pulmonary fibrosis augurs a very poor prognosis).[consultant360.com]
  • The term terminal respiratory insufficiency refers to the grave prognosis. Hypoxia is dangerous because its effects are irreversible, while hypercapnia is reversible.[zuniv.net]


  • Consequently, the individual contribution of diffusion defects to the hypoxemia caused by the etiologies listed below is unknown.[pathwaymedicine.org]
  • Página 330 - Intestinal infections in patients with the acquired immunodeficiency syndrome (AIDS): etiology and response to therapy. ‎[books.google.es]
  • Practically all categories in the chapter could be designated 'not otherwise specified', 'unknown etiology' or 'transient'.[icd10data.com]
  • Assessment of alpha-1-antitrypsin deficiency heterozygosity as a risk factor in the etiology of emphysema. J Clin Invest. 1979;63(2):299–309. 40. King PT, Holdsworth SR, Freezer NJ, et al.[aafp.org]


  • DISCUSSION As an index of pulmonary gas exchange, the test for DLCO, as well as the other lung function tests has been widely accepted in clinical practices or epidemiologic studies of disease of the respiratory system.[kjim.org]
  • Increased mortality among persons with rheumatoid arthritis, but where RA does not appear on death certificate. eleven-year follow-up of an epidemiological study. Scand J Rheumatol. 1981;10(4):301-6. Isomaki HA, Mutru O, Koota K.[hopkinsarthritis.org]
  • Cancer Epidemiology, Biomarkers & Prevention. doi: 10.1158/1055-9965.EPI-08-0422. Fonti utilizzate nelle precedenti revisioni (2006 November). Cystic Fibrosis Fact Sheet. American Lung Association [On-line information]. Available online at through .[labtestsonline.it]
  • Thoracic kyphosis and ventilatory dysfunction in unselected older persons: an epidemiological study in Dicomano, Italy. J Am Geriatr Soc. 2004;52(6):909–915. 29. Bilińska M, Aloszko A, Wasilewska E, Kurowski W, Mincewicz G, Nyka WM.[aafp.org]
Sex distribution
Age distribution


  • Página 302 - Groszmann RJ, Atterbury CE: The pathophysiology of portal hypertension: a basis for classification. Semin Liver Dis 1982; 2:177. ‎[books.google.es]
  • Overview It should be pointed out that any etiology resulting in significant pathological changes to the alveolar membrane likely also result in other pathophysiological mechanisms of hypoxemia, especially Ventilation-Perfusion Defects.[pathwaymedicine.org]
  • The pathophysiology of pulmonary diffusion impairment in human immunodeficiency virus infection. Am J Respir Crit Care Med. 1999;160(1):272-277.[consultant360.com]
  • Interstitial Lung Disease: Pathophysiology and Genetic Predisposition. Medscape General Medicine 2(1), 2000 [On-line information]. Available online at through . Brain, J. (2006 August, Revision). Biology of the lungs and airways.[labtestsonline.it]
  • In order to understand these tests, it is helpful to briefly review the pathophysiology of asthma. Asthma is a disease characterized by a hyperresponsive airway. The smooth muscles in the airway (bronchi) contract causing a decrease in airflow.[iaff.org]


  • Página 302 - Lee GC-Y, et al: Prevention of perinatally transmitted hepatitis B virus infection with hepatitis B immune globulin and/or HB vaccine, in Vyas GN, Dienstag JL, Hoofnagle JH (eds): Viral Hepatitis and Liver Disease. ‎[books.google.es]
  • Centers for Disease Control and Prevention. Tuberculosis (TB). Available online at through . Accessed June 21, 2014. Cystic Fibrosis Foundation. Why are Newborns Screened for Cystic Fibrosis? Available online at through . Accessed June 20, 2014.[labtestsonline.it]
  • […] fullThoracic deformity preventing full inflationinflation 12.  Diseases that reduce QVc and thus reduceDiseases that reduce QVc and thus reduce DL,CODL,CO • AnaemiaAnaemia • Pulmonary emboliPulmonary emboli  Other conditions that reduce QVc and thusOther[slideshare.net]
  • Your doctor will place clips on your nose to prevent you from breathing through your nostrils. You’ll take a breath of air. This air will contain a tiny, and safe, amount of carbon monoxide. You’ll hold this air for a count of 10 or so.[healthline.com]

Ask Question

5000 Characters left Format the text using: # Heading, **bold**, _italic_. HTML code is not allowed.
By publishing this question you agree to the TOS and Privacy policy.
• Use a precise title for your question.
• Ask a specific question and provide age, sex, symptoms, type and duration of treatment.
• Respect your own and other people's privacy, never post full names or contact information.
• Inappropriate questions will be deleted.
• In urgent cases contact a physician, visit a hospital or call an emergency service!