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Degenerative Myopia

Pathological Myopia


Presentation

  • Presents a more streamlined format to the printed text to help you focus on the clinically actionable information you need everyday.[books.google.com]
  • Pathological myopes may present with any of the following abnormal signs: Decreased visual acuity An unusually large exophoria Strabismus (typically exotropia) Open-angle glaucoma Premature lenticular opacification Increased axial length Internally the[decisionmakerplus.net]
  • The eyes treated for axial myopia control have had significant macular schisis present in fewer than 15% of the cases. Where schisis was present, additional tension was provided to the buckle.[retinalphysician.com]
  • A major feature of the book is the presentation of many case studies, with generous use of full-color photographs to show in detail the course of fundus changes.[books.google.com]
Accelerated Growth
  • An affected individual will show accelerated growth of the size of the eye during the normal growth-periods of childhood and adolescence, so that, by the late teens, or the early twenties, the eye is much longer than normal.[mvrf.org]
Strabismus
  • Pathological myopes may present with any of the following abnormal signs: Decreased visual acuity An unusually large exophoria Strabismus (typically exotropia) Open-angle glaucoma Premature lenticular opacification Increased axial length Internally the[decisionmakerplus.net]
  • Of 178 patients in the study, 75.8% had amblyopia or reduced visual acuity, 31.5% had strabismus (eso or exo equal), and 35.4% had anisometropia.[optometrystudents.com]
  • Blacks, and South Sea Islanders Myopia is more common in urban communities than in rural ones MYP19 In 2010, a genetic locus was mapped to 5p13.3–5p15.1 in a Chinese family with autosomal dominant high myopia Patients who have excessive myopia often have strabismus[slideshare.net]
  • OCULAR MANIFESTATIONS The more important anatomical and functional abnormalities found in extremely myopic individuals are listed in Box 126-1 .[9] Patients who have excessive myopia often have strabismus, especially exophoria and exotropia, and are more[medtextfree.wordpress.com]
  • RRD 143,169 S school myopia 26,46 SCORM 35 SCORM Study 37 SHH 194 simple myopia 26,46 Singapore Cohort Study on the Risk Factors for Myopia 35 SM 157 Smith 5,69 SNP 35 sonic hedgehog 194 Sorsby 16 spectacle magnification 157 SRK/T 160 Stickler症候群 166 strabismus[rnavi.ndl.go.jp]
Bitot's Spots
  • Bitot spots small, circumscribed, lusterless, grayish white, foamy, greasy, triangular deposits on the bulbar … Medical dictionary miopía degenerativa — Eng.[translate.academic.ru]
Blue Sclera
  • sclera ( Q13.5 ) degenerative myopia ( H44.2 - ) Change (s) (in) (of) - see also Removal retina H35.9 ICD-10-CM Diagnosis Code H35.9 Unspecified retinal disorder 2016 2017 2018 2019 Billable/Specific Code myopic H44.2- - see also Myopia, degenerative[icd10data.com]
Withdrawn
  • In children, topical atropine can effectively slow enlargement of the myopic eye and the effect is sustained even after the drug has been withdrawn. [6] However, the possibility of long-term light damage to eyes that have dilated pupils has been investigated[medtextfree.wordpress.com]
Pierre Robin Syndrome
  • Systemic Associations of Degenerative Myopia Albinism Congenital rubella de Lange’s syndrome Down’s syndrome Ehlers–Danlos syndrome Fetal alcohol syndrome Gyrate atrophy—hyperornithinemia Laurence–Moon–Bardet–Biedl syndrome Marfan’s syndrome Pierre Robin’s[medtextfree.wordpress.com]
Neglect
  • Degenerative myopia deserves our recognition as one of the truly neglected areas of ophthalmology.[mvrf.org]
Insomnia
  • With 52 questions in total, subjects such as shopping, salary, insomnia, and activities with friends were addressed, among others. It was concluded that the functional status of daily life and the quality of life of these patients was reduced.[optometrystudents.com]

Workup

Sinus Arrest
  • In all three individuals, the basic manifestations of the SSS were total sinus arrest with secondary AV junctional rhythm at a normal rate.[ncbi.nlm.nih.gov]

Treatment

  • Sixteen eyes required only one treatment. Three eyes required more than one because of incomplete closure of the new vessels after the first treatment.[ncbi.nlm.nih.gov]
  • Scar expansion was noted in 35 cases (97%), without a significant loss of visual acuity during the first year after treatment.[ncbi.nlm.nih.gov]
  • In 15 of the 16 eyes with V, new vessels, complete closure was achieved with one treatment; one eye required two treatments.[healio.com]
  • If this occurs, immediate treatment is needed, which may be in the form of photodynamic therapy, antiangiogenic drug treatment or both. (Source: www.revoptom.com) Treatment for Prevention of Degenerative Myopia Four treatments are showing promise.[lowvision.preventblindness.org]
  • Unfortunately, there is no treatment for retinal atrophy. Another potential cause of vision loss is abnormal blood vessel growth which can cause bleeding and swelling of the retina.[neretina.com]

Prognosis

  • Clinical course and prognosis: Chronic progressive myopia will result in increasing loss of visual acuity. The prognosis for subretinal neovascularization is poor. The incidence of retinal detachment is higher in myopic eyes.[alpfmedical.info]
  • […] encyclopedic reference this atlas provides an up-to-date clinical overview of all the major areas of ophthalmology including, epidemiology and etiology, history, physical examination, differential diagnosis, laboratory and special examinations, diagnosis, prognosis[books.google.com]
  • This study confirmed the poor long term prognosis of myopic CNV with observation.[bjo.bmj.com]
  • Continued break formation results in a reticular pattern that usually is most obvious in the deepest recess of the staphyloma and portends a guarded prognosis for central vision.[medtextfree.wordpress.com]
  • Patients with retinal detachments, myopic macular degeneration and staphylomas may have a poorer prognosis depending upon the location of the problem.[eyeassociates.com]

Etiology

  • Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology.[icd10coded.com]
  • Written to be a "go-to" field manual rather than an encyclopedic reference this atlas provides an up-to-date clinical overview of all the major areas of ophthalmology including, epidemiology and etiology, history, physical examination, differential diagnosis[books.google.com]
  • Introduction The degenerative myopia is often associated with blindness and the etiology is still not clear.[medical-clinical-reviews.imedpub.com]
  • Etiology of Myopia is as diverse and controversial as one can imagine. Everything in medicine has been blamed as a cause of Myopia.[ijo.in]
  • Progressive myopia: a possible etiologic factor. Trans Am Ophthalmol Soc. 1942;40:340-54. 8. Czepita D. [Contemporary views on the etiology, pathogenesis as well as treatment of school-age and progressive myopia] Klin Oczna. 1999;101(6):477-80. 9.[reviewofoptometry.com]

Epidemiology

  • Written to be a "go-to" field manual rather than an encyclopedic reference this atlas provides an up-to-date clinical overview of all the major areas of ophthalmology including, epidemiology and etiology, history, physical examination, differential diagnosis[books.google.com]
  • Epidemiology: Chorioretinal atrophy due to myopia is rare. Pathogenesis: The atrophy usually occurs in the presence of severe myopia exceeding minus 6 diopters.[alpfmedical.info]
  • Generally, myopia is the result of elongated axial length in the region of 25.5 or 26.5mm. (1,2) Degenerative myopia is also known as other terminology including: High Myopia Degenerative Myopia Pernicious Myopia Malignant Myopia EPIDEMIOLOGY The epidemiology[optometrystudents.com]
  • American Journal of Epidemiology . April 1993. About the Author: Gary Heiting, OD, is senior editor of AllAboutVision.com. Dr.[allaboutvision.com]
  • Epidemiologic study of the prevalence and severity of myopia among schoolchildren in Taiwan in 2000. J Formos Med Assoc. 2001 Oct;100(10):684-91. 4. Lin LLK, Jan JH, Shin YF, et al.[reviewofoptometry.com]
Sex distribution
Age distribution

Pathophysiology

  • It is indeed similar to AMD in pathophysiology but the damage to Bruch's membrane, rods, cones do not come from age related changes but from mechanical stretching of the tissues from the very long myopic eye. I cannot give you an incidence rate.[medhelp.org]
  • Although the pathophysiology is unknown, there are evidences - as the world standard for the disease distribution-indicating genetic influences.[medical-clinical-reviews.imedpub.com]
  • We suggest that the increase in sCD44 concentration in POAG AH is secondary to an underlying heterogeneous pathophysiology and that AH levels of sCD44 may be influenced by other factors.[bmcresnotes.biomedcentral.com]
  • The pathophysiology of this progressive, degenerative form of myopia is unknown.[medtextfree.wordpress.com]
  • However, the functional changes induced by the structural changes and the possible pathophysiologic mechanisms are still being researched.[nature.com]

Prevention

  • A proprietary treatment developed through collaboration of Visdex, Caltech and UCSF successfully stabilizes scleral shape and prevents globe enlargement in vitro.[sbir.gov]
  • Buckling adult eyes can stabilize axial length and minimize future macular degeneration, but it cannot prevent the continuation of degenerative processes, which are already at work.[mvrf.org]
  • For more information from other health sites, please visit the following webpages: Digital Reference of Ophthalmology, Degenerative Myopia Prevent Blindness, Degenerative Myopia Royal National Institute of Blind People, High degree myopia You may wish[nei.nih.gov]
  • Myopia can be caused by a longer than normal eyeball or by any condition that prevents light rays from focusing on the retina. Most forms of myopia can be… … Medical dictionary Matha Ayurveda Eye Hospital — Inspired by vision...[translate.academic.ru]

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