Hypopituitarism may present with loss of anterior or posterior pituitary hormones. [aippg.net]

uterus present - Hypothalamic dysfunction; pituitary lesion; PCOS; ovarian insufficiency Breasts present, uterus absent - Müllerian agenesis; complete androgen insensitivity Breasts absent, uterus present - Hypogonadotropic hypogonadism; gonadal dysgenesis [emedicine.medscape.com]

Research presented by: R.L. Matchock - University of Pennsylvania The prenatal environment of the human fetus is now known to have lasting physiological and behavioral effects into childhood and adulthood. [handresearch.com]

A companion Website includes a Student Study Guide, Laboratory Manual, Instructor's Guide, Brownstone Test Generator, PowerPoint presentations, and images from the book. [books.google.de]

The peak growth spurt and other changes such as voice breaking, muscle bulking and facial hair growth are not usually present for another two years. [gponline.com]

• Pain

  Conclusion and Implications for Translation: Most of the respondents were experienced early menarche and suffered from menstrual pain. The sociodemographic factors were found significantly associated with age at menarche. [ijtmrph.org]

  陣痛 laparoscopy腹腔鏡検査 laparotomy１．開腹［術］　２．側腹切開［術］ last menstrual period最終月経 late deceleration遅発一過性徐脈 leiomyosarcoma of the uterus子宮平滑筋肉腫 length of the fundus uteri子宮底長 lower abdominal pain下腹［部］痛 lower back pain腰痛 lumbago腰痛 luteinizing hormone (LH)黄体化ホルモン [tokyo-med.ac.jp]

  The time between menarche and painful periods (presumably ovulatory cycles) is about 24 months. This varies quite a bit and cannot be counted on as a method of birth control. [pamf.org]

  Period pains respond well to anti-inflammatories - eg, mefenamic acid. Some women may need a combination of towels and tampons for overnight use, to prevent soiling bed linen. [patient.info]

• Anemia

  Various disorders, such as diabetes mellitus, inflammatory bowel disease, kidney disease, cystic fibrosis, and anemia, can delay or prevent sexual development. [merckmanuals.com]

  […] episodes of epistaxis per month or frequent bruising. [33] Another screening tool, specifically for adolescents, includes a history of menses longer than 7 days, a “flooding” or “gushing” sensation, bleeding through a pad or tampon in 2 hours, a history of anemia [emedicine.medscape.com]

  "Reproductive endocrine issues in men with sickle cell anemia". Andrology. 5 (4): 679–690. doi : 10.1111/andr.12370. PMID 28662541. ^ Castaldi MA, Cobellis L (June 2016). "Thalassemia and infertility". [en.wikipedia.org]

• Disability

  Please enable JS and disable any ad blocker [contemporarypediatrics.modernmedicine.com]

• Tall Stature

  shield chest, and low hairline. [4] Klinefelter syndrome presents with tall stature as well as small, firm testes. [4] Genetic or acquired defect of the hormonal pathway of puberty [ edit ] Lacking the sense of smell ( anosmia ) along with delayed puberty [en.wikipedia.org]

• Short Stature in Children

  […] studies show that these children fall short of their target height from about 4 to 11 cm. [43] Factors that could affect final height include familial short stature and pre-pubertal growth development. [43] Pubertal delay can also affect bone mass and [en.wikipedia.org]

• Fracture

  Sixty-nine percent of the fractures that were described were stress fractures (mostly in the metatarsals), and their occurrence had an even stronger correlation with increased age at menarche. [ncbi.nlm.nih.gov]

  The loss of bone density makes the athlete liable to stress fractures initially, but can later lead to osteoporosis. [standardmedia.co.ke]

  The presence of stress fractures in young women should be investigated. [healthofchildren.com]

  Impact on long-term health The main impact on long term health in those with pubertal delay is the risk of skeletal impact with lower bone density and increased fracture risk over a lifetime. [clinicaladvisor.com]

  "Pathological fractures in paediatric patients with inflammatory bowel disease". European Journal of Pediatrics (Review). 173 (2): 141–51. doi : 10.1007/s00431-013-2174-5. PMID 24132387. ^ Corica D, Romano C (February 2017). [en.wikipedia.org]

• Muscle Weakness

  weakness, loss of axillary and pubic hair in females -Prolactin deficiency: failure of lactation in post-partum patients Loss of posterior pituitary hormones: -ADH deficiency: polyuria, thirst [aippg.net]

• Fear

  While developmental stressors such as early separation and stranger anxiety, novelty stress, and fear-evoked personal distress, arise during normal development, clinical stressors result from certain conditions that are relatively common in infancy and [books.google.com]

  It can also be seen in girls with anorexia nervosa, who engage in extreme dieting or binging and purging, because they fear becoming too fat even when they are abnormally thin. [healthychildren.org]

  Emotional stress - eg, fear of pregnancy/phantom pregnancy. Significant Illness. Medication - eg, hormones, cytotoxics, some psychotropic drugs (eg, risperidone). Investigations and management These will depend on the possible cause. [patient.info]

  KEY TERMS Anorexia nervosa —An eating disorder marked by an unrealistic fear of weight gain, self-starvation, and distortion of body image. It most commonly occurs in adolescent females. [healthofchildren.com]

• Seizure

  Neurologic symptoms such as headache, dyskinisia, seizures, and mental retardation suggest a disorder of the central nervous system. [clinicaladvisor.com]

• Delayed Menarche

  Primary amenorrhea is characterized by delayed menarche. [eng.ichacha.net]

  05th Apr 2009 00:00:00 GMT +0300 AL Gondi Delayed menarche means delayed onset of monthly periods. Girls who participate in sports usually experience delayed menarche for at least a year or two than other sedentary girls. [standardmedia.co.ke]

  Retrospective, self-report data on menarcheal age were obtained from 206 healthy female college students, as well as finger length ratio data from both hands. Low right-hand 2D:4D ratios (but not left-hand) were associated with delayed menarche. [ncbi.nlm.nih.gov]

  To analyse the correlation of these factors with delayed age of menarche. [nepjol.info]

• Amenorrhea

  The dancers with scoliosis had a slightly higher prevalence of secondary amenorrhea (44 percent vs. 31 percent), the mean (+/- SD) duration of their amenorrhea was longer (11.4 +/- 18.3 vs. 4.1 +/- 7.4 months; P less than 0.05), and they scored higher [ncbi.nlm.nih.gov]

  We report here on 89 young ballet dancers among whom there was a high incidence of primary amenorrhea, secondary amenorrhea, irregular cycles, and delayed menarche — an incidence correlated with excessive thinness. [dash.harvard.edu]

  primary amenorrhea (diagnosis), Amenorrhoea primary, amenorrhea primary, Amenorrhea, primary, Primary amenorrhoea (finding), Primary Amenorrhea, Delayed Menarche, Primary physiologic amenorrhea, Primary amenorrhea, Primary amenorrhoea, Primary physiologic [fpnotebook.com]

  In a study of 89 female ballet dancers, while 1/3 of the women reported normal cycles, 15% reported secondary amenorrhea and 30% reported irregular cycles. [agris.fao.org]

  Definition Amenorrhea is the medical term for the absence of menstruation. There are two types of amenorrhea, primary and secondary. [healthofchildren.com]

• Primary Amenorrhea

  amenorrhea, primary amenorrhea (diagnosis), Amenorrhoea primary, amenorrhea primary, Amenorrhea, primary, Primary amenorrhoea (finding), Primary Amenorrhea, Delayed Menarche, Primary physiologic amenorrhea, Primary amenorrhea, Primary amenorrhoea, Primary [fpnotebook.com]

  Primary amenorrhea is characterized by delayed menarche. [eng.ichacha.net]

  There are multiple ways of categorizing the causes of primary amenorrhea. [emedicine.medscape.com]

  We report here on 89 young ballet dancers among whom there was a high incidence of primary amenorrhea, secondary amenorrhea, irregular cycles, and delayed menarche — an incidence correlated with excessive thinness. [dash.harvard.edu]

  Definition Amenorrhea is the medical term for the absence of menstruation. There are two types of amenorrhea, primary and secondary. [healthofchildren.com]

This item is withdrawn What is the workup of delayed menarche? - WITHDRAWN 2018 (hdl:10355/7394) This item is restricted. If you have a login to access this item: Proceed to the login screen and log in. [mospace.umsystem.edu]

These can be ruled out by means of blood tests (see Workup ). Finally, endometrial malignancy, though rare in women younger than 40 years, should also be on the differential diagnosis for adolescents with irregular menses. [emedicine.medscape.com]

[…] healthy physical development. [2] Delay of puberty may also occur due to various causes such as malnutrition, various systemic diseases, or defects of the reproductive system ( hypogonadism ) or the body's responsiveness to sex hormones. [2] Initial workup [en.wikipedia.org]

• Hypoglycemia

  Página 31 - Zapf J, Walter H, Froesch ER: Radioimmunological determination of insulin-like growth factors I and II in normal subjects and in patients with growth disorders and extrapancreatic tumor hypoglycemia. J Clin Invest 1981;68:1321-1330. ‎ [books.google.es]

Does my child need treatment for delayed puberty? What are the options for treatment? What are the risks and benefits of each treatment option? How long will my child need treatment? Edited: November 2017 [hormone.org]

[…] nodules; and new coverage of when and when not to use radioiodine in the treatment of patients with thyroid cancer. [books.google.de]

However, treatment with sex hormones according to the sex of the individual (testosterone or estrogen) can help to boost the hormone levels and induce puberty. [news-medical.net]

Treatment options include monthly depot testosterone esters or daily oral capsules. Transdermal testosterone is under evaluation in this age group. [gponline.com]

Treatment of cause Hormone therapy The treatment for delayed puberty depends on its cause. When an underlying disorder is the cause of delayed puberty, puberty usually proceeds once the disorder has been treated. [merckmanuals.com]

Despite an obvious cause, pubertal assessment is necessary as active treatment of the delay in growth and puberty can improve the growth prognosis, reduce long-term risk of osteoporosis and boost self-esteem, so a referral is beneficial. [gponline.com]

Prognosis The prognosis of either primary or secondary amenorrhea depends on the underlying cause. [healthofchildren.com]

Prognosis and outcome Long-term prognosis In individuals with premature ovarian failure as a cause of delayed puberty, amenorrhea is likely permanent and the possibility of spontaneous pregnancy is Overall treatment of the predisposing cause of pubertal [clinicaladvisor.com]

[…] premature ovarian failure早発閉経（早発卵巣機能不全） premature rupture of themembranes前期破水 premature separation ofnormally implanted placenta常位胎盤早期剥離 premenstrual syndrome月経前症候群（月経前緊張症） presentation胎位 preterm早期 primordial follicle原始卵胞 primordial germ cell原始生殖細胞 prognosis [tokyo-med.ac.jp]

[…] associated with ambiguous genitalia, hyperandrogenism, and Cushing syndrome. [11] Yet another method of categorizing the etiologies of primary amenorrhea involves evaluating the components of the hypothalamic-pituitary-ovarian (HPO) axis as well as the [emedicine.medscape.com]

The primary distinction should be made between those etiologies that result in permanent disruption of hormonal function and those that will be transient or modifiable. [clinicaladvisor.com]

Treatment depends on the etiology. McCune-Albright Syndrome. [aafp.org]

] Although serum growth hormone levels are low in constitutional delay of puberty, they increase after treatment with sex hormones and in those cases, growth hormone is not suggested to accelerate growth. [8] Subnormal vitamin A intake is one of the etiological [en.wikipedia.org]

Osteoporosis in children and adolescents: etiology and management. Paediatr Drugs 2005;7:295-323. 52. Nichols JF, Rauh MJ, Lawson MJ, Ji M, Barkai HS. Prevalence of the female athlete triad syndrome among high school athletes. [redorbit.com]

OBJECTIVES: To assess how much of the epidemiologic association between PFAS and delayed menarche can be explained by the correlation of growth and maturation with PFAS body burden. [ncbi.nlm.nih.gov]

Collaborative Group on Hormonal Factors in Breast Cancer: Menarche, menopause, and breast cancer risk: Individual participant meta-analysis, including 118,964 women with breast cancer from 117 epidemiological studies. [ascopost.com]

Another study, published in Cancer Epidemiology, Biomarkers & Prevention, found that ovarian cancer patients whose age of first menstrual cycle was younger than 12 were associated with higher mortality rates—they were 51 percent more likely to die from [splinternews.com]

"Celiac disease and reproductive disorders: meta-analysis of epidemiologic associations and potential pathogenic mechanisms". Human Reproduction Update (Review). 20 (4): 582–93. doi : 10.1093/humupd/dmu007. [en.wikipedia.org]

As noted (see Pathophysiology ), cycles are not consistently ovulatory for the first few years after menarche, especially if menarche occurs at a later age. [emedicine.medscape.com]

The pathophysiology is largely unknown. Iatrogenic - hormones used for contraception or hormone replacement therapy (HRT) or management of other conditions. [patient.info]

The occurrence of menarche after an injury preventing dancing supports the hypothesis that a change in fatlean ratio and the accompanying changes in metabolic and hormonal levels characteristic of hard physical exercise may be involved in the delay of [bisp-surf.de]

If the goal is to prevent inbreeding, having sex with a half-sibling who shares 50 percent of your genes might also seem like a bad idea. [livescience.com]

[…] from sending the “start puberty” signal conditions that prevent the ovaries or testes from being able to respond to the “start puberty” signal certain genetic conditions, such as Klinefelter’s syndrome in boys and Turner syndrome in girls 3. [childrenshospital.org]

Prevention Amenorrhea related to pregnancy, the female athletic triad, drug or alcohol abuse, or eating disorders is preventable insofar as these are lifestyle choices. [healthofchildren.com]

Various disorders, such as diabetes mellitus, inflammatory bowel disease, kidney disease, cystic fibrosis, and anemia, can delay or prevent sexual development. [merckmanuals.com]