Symptoma

Dendritic Cell Sarcoma Not Otherwise Specified

The Demos Surgical Pathology Guides series presents in summary and visual form the basic knowledge base that every practicing pathologist needs every working day. [books.google.de]

Presents an in-depth differential diagnosis discussion for all major entities. Examines the role of special techniques such as immunohistochemistry, flow cytometry, and molecular biology in resolving difficulties in interpretation and diagnosis. [books.google.com]

Case presentation : We report the case of a 14 year-old white girl who presented with a nodular lesion in the thigh, involving the skin and soft tissue. The histologic diagnosis retained was a HS. [latunisiemedicale.com]

He then presented with left cervical lymphadenopathy 2.5 years later and underwent a left neck dissection with similar pathology. A discussion of the disease process and WTC exposure is presented. [casereports.bmj.com]

  • Lymphadenopathy

    The chapters cover infectious lymphadenopathies, reactive lymphadenopathies, lymphadenopathies associated with systemic disorders, lymph node inclusions, spindle cell neoplasms of lymph nodes, foreign body lymphadenopathies, mature B-cell neoplasms, precursor [books.google.de]

    […] with Massive Lymphadenopathy (Rosai-Dorfman Disease); Kikuchi-Fujimoto Lymphadenopathy; Sarcoidosis; Systemic Lupus Erythematosus Lymphadenopathy; Rheumatoid Lymphadenopathy; Castleman Disease; Hyaline Vascular Castleman Disease; Unicentric Castleman [springerpub.com]

    He then presented with left cervical lymphadenopathy 2.5 years later and underwent a left neck dissection with similar pathology. A discussion of the disease process and WTC exposure is presented. [casereports.bmj.com]

    Reactive Lymphadenopathy Normal Lymph Node B-cell development Anatomy and cells Immunostaining patterns Primarily Follicular Pattern Reactive follicular hyperplasia Progressive transformation of germinal centers Human immunodeficiency virus lymphadenitis [enjoypath.com]

    Multicentric/Plasma Cell Variant Foreign Body Lymphadenopathy Dermatopathic Lymphadenopathy Non-Specific Lymphadenopathy VIII. [euro-libris.ro]

  • Hodgkin Lymphoma

    Lymphoma [ edit ] Nodular lymphocyte-predominant Hodgkin lymphoma Classical Hodgkin lymphoma Nodular sclerosis Hodgkin lymphoma (grades 1 and 2) Lymphocyte-rich classical Hodgkin lymphoma Mixed cellularity Hodgkin lymphoma Lymphocyte depletion Hodgkin [en.wikibooks.org]

    T-Cell Lymphoma; Anaplastic Large Cell Lymphoma, ALK Positive; Anaplastic Large Cell Lymphoma, ALK Negative; Hodgkin Lymphoma : Nodular Lymphocyte Predominant Hodgkin Lymphoma; Nodular Sclerosis Classical Hodgkin Lymphoma; Mixed Cellularity Classical [springerpub.com]

    lymphoma, in 12 of 12 cases (100%) of nodular lymphocyte-predominant Hodgkin lymphoma, and in 27 of 31 cases (87%) of primary mediastinal (thymic) large B-cell lymphoma. [ncbi.nlm.nih.gov]

    古典的ホジキンリンパ腫　Classical Hodgkin lymphoma: CHL (田丸　淳一) 517 3. 結節硬化型古典的ホジキンリンパ腫　Nodular sclerosis classical Hodgkin lymphoma: NSCHL (浅野　直子) 521 4. 混合細胞型古典的ホジキンリンパ腫　Mixed cellularity classical Hodgkin lymphoma: MCCHL (浅野　直子) 523 5. [rnavi.ndl.go.jp]

  • Pathologist

    The Demos Surgical Pathology Guides series presents in summary and visual form the basic knowledge base that every practicing pathologist needs every working day. [books.google.de]

    Edited by four leading surgical pathologists - Noel Weidner, MD, Richard J. Cote, MD, Saul Suster, MD and Lawrence M. [books.google.com]

  • Swelling

    The most common symptom is a painless swelling of a lymph node, usually in the neck. But a swelling can develop elsewhere in the lymphatic system. Follicular dendritic cell sarcomas are described as indolent, which means they grow slowly. [cancerresearchuk.org]

    The patient presented with swelling of the left tonsil and resultant difficulty in swallowing for last three months. The tumor was excised and was sent for histopathologic examination. [njms.in]

    30222603 ) Walters M...Rech KLG 2018 15 Follicular Dendritic Cell Sarcoma of Gastrointestinal Tract: an Uncommon Lesion, Commonly Missed. ( 30430359 ) Hassan U...Akhter N 2018 16 Unusual Presentation of Follicular Dendritic Cell Sarcoma as a Cystic Neck Swelling [malacards.org]

    Clinically, most patients presented with a painless swelling. [ijpmonline.org]

    The patient underwent surgical excision of the swelling by a partial left parotidectomy with preservation of the facial nerve. [diagnosticpathology.biomedcentral.com]

  • Falling

    Poorer prognosis: intra-abdominal presentation, significant cytologic atypia, extensive coagulative necrosis, high proliferation index, large tumor 6cm o 10% to 20% pts die of disease, often after a long time o Occasional dendritic cell neoplasms do not fall [hemepathreview.com]

  • Aspiration

    Includes recommendations from the 2008 National Cancer Institute Thyroid Fine Needle Aspiration State of the Science Conference. [books.google.com]

    Haranhalli N....Altschul D.J. 2017 19 Comprehensive Genomic Profiling of a Rare Thyroid Follicular Dendritic Cell Sarcoma. ( 28975018 ) Davila J.I....Asmann Y.W. 2017 20 Cytomorphological Findings of Follicular Dendritic Cell Sarcoma on Fine-Needle Aspiration [malacards.org]

    Fine-needle aspiration of primary and recurrent dermatofibrosarcoma protuberans. Diagn Cytopathol. 2004 Apr;30(4):261-5. 22. [No authors listed]. Soft tissue sarcoma. In: Greene PL, Page DL, Fleming ID, eds. AJCC cancer staging manual (6th edition). [sarcomahelp.org]

    PubMed Central View Article PubMed Google Scholar Fan YS, Ng WK, Chan A, Chan GS, Tsang J, Chim CS, Ip P: Fine needle aspiration cytology in follicular dendritic cell sarcoma: a report of two cases. [diagnosticpathology.biomedcentral.com]

    Fine needle aspiration cytology in follicular dendritic cell sarcoma: a report of two cases. Acta Cytol. 2007 ; 51 : 642 – 647. 29.. Diagnosis and recurrence of follicular dendritic cell sarcoma. [academic.oup.com]

  • Stroke

    […] all the latest approaches in clinical laboratory medicine with new and updated coverage of: the chemical basis for analyte assays and common interferences; lipids and dyslipoproteinemia; markers in the blood for cardiac injury evaluation and related stroke [books.google.com]

  • Human Papillomavirus

    2017 23 Identification of novel follicular dendritic cell sarcoma markers, FDCSP and SRGN, by whole transcriptome sequencing. ( 28145886 ) Lorenzi L....Hartmann S. 2017 24 p16 expression in follicular dendritic cell sarcoma: a potential mimicker of human [malacards.org]

Treatment with chemotherapy along with adjuvant radiation therapy was successful in decreasing the size of the nasopharyngeal mass, and the patient remained free of any evidence of recurrence nearly 5 years after treatment. [jhu.pure.elsevier.com]

Authored by international experts in the field, it covers a broad range of hematologic disorders -- both benign and malignant -- with information on the pathogenesis, clinical and pathologic diagnosis, and treatment for each. [books.google.com]

Treatment As follicular dendritic cell sarcoma is very rare, doctors are still trying to work out the standard treatment. Your specialist will discuss this with you. [cancerresearchuk.org]

[…] o Vesicular chromatin, small to large distinct · Immunophenotype o S-100 o Negative for vimentin and CD1a o Variably, weakly for CD68, lysozyme, and CD45 o Negative for FDCs (CD21 and CD35), MPO, CD34, specific B and T-cell antigens, CD30, CK, EMA · Prognosis [hemepathreview.com]

Prognosis As a low grade sarcoma with high local recurrence rate but low metastasis risk  Overall recurrence: 43%  Overall metastasis: 24%  Overall mortality: 17% Cancer. 1997;79:294–313.  2-year recurrence free survival: 62.3%  5-year recurrence [slideshare.net]

 Complete surgical resection is the therapy of choice  Adjuvant radiation or chemotherapy showed indeterminate benefit  The optimal combination treatment for FDC sarcoma has yet to be defined  Imatinib may be benefit Onkologie 2007;30:381–384 12 Prognosis [slideplayer.com]

Rutgers EJ, Kroon BR, Albus-Lutter LE, et al: Dermatofibrosarcoma protuberans: treatment and prognosis. Eur J Surg Oncol 1992; 18:241-248. 48. Snow S, Gordon EM, Larson PO, Bagheri MM, Bentz ML, Sable DB. [sarcomahelp.org]

PubMed Central PubMed Google Scholar Li L, Shi YH, Guo ZJ, Qiu T, Guo L, Yang HY, Zhang X, Zhao XM, Su Q: Clinicopathological features and prognosis assessment of extranodal follicular dendritic cell sarcoma. [diagnosticpathology.biomedcentral.com]

Etiology FDC express CD21 which is EBV receptor, however the correlation is not well documented Hyaline-vascular Castleman disease may be a predisposing factor to FDC p53 pathway may play a role Epidermal growth factor receptor(EGFR) expression has [slideshare.net]

Onset age is various (9-82), mean age is about 50  Female: male: 1.2:1  Presentation: Painless, slow-growing mass  Lab: anemia and elevated ALP in liver FDC  Tumor is enhanced in PET Hepatobiliary Pancreat Dis Int ， Vol 10 ， No 4 August 15 ， 2011 6 Etiology [slideplayer.com]

Cervical LNs most often affected o Also common LNs: maxillary, mediastinal, mesenteric and retroperitoneum o Extranodal sites: tonsil, spleen, oral cavity, GI tract, liver, soft tissue, skin, and breast o Common sties of metastasis: LNs, lung, and liver · Etiology [hemepathreview.com]

The etiology and pathogenesis of FDCS are not well understood. Chan et al 13 reported a case of nasopharyngeal hyaline-vascular Castleman disease that progressed to FDCS. [academic.oup.com]

Epidemiology 80 cases was documented until 2011 in English literature Pancreat Dis Int，Vol 10，No 4 • August 15，2011 Hepatobiliary Onset age is various (9-82), mean age is about 50 Female: male: 1.2:1 Presentation: Painless, slow-growing mass Lab: [slideshare.net]

[…] nodes  Extranodal FDCS mostly affected intra-abdominal organs and involves a wide variety of sites, including spleen, gastrointestinal tract, liver, soft tissue, skin, lung, and breast  Metastatic disease is common in lymph nodes, lung, and liver 5 Epidemiology [slideplayer.com]

Descriptive epidemiology of dermatofibrosarcoma protuberans in the United States, 1973 to 2002. J Am Acad Dermatol. 2007 Jun;56(6):968-73. Epub 2006 Dec 1. 13. Taylor HB, Helwig EB: Dermatofibrosarcoma protuberans: a study of 115 cases. [sarcomahelp.org]

Get optimal test results with guidance on error detection, correction, and prevention as well as cost-effective test selection. [books.google.com]

Efficacy and safety of febuxostat for prevention of tumor lysis syndrome in patients with malignant tumors receiving chemotherapy : a phase III, randomized, multi-center trial comparing febuxostat and allopurinol. Int J Clin Oncol. [jshem.or.jp]