Presentation
There was no honeycombing on CT or HRCT scans at presentation. [ncbi.nlm.nih.gov]
[…] but scattered Eosinophils frequently present but sparse, neutrophils absent Alveoli lined by reactive alveolar lining cells Occurring in smokers' lungs, other clinicopathologic disorders such as chronic bronchitis and emphysema are frequently present [surgpathcriteria.stanford.edu]
Some multinucleate histiocytic cells are often present. [histopathology-india.net]
Presentation tends to be in middle age (30-60 years of age) with progressive shortness of breath and chronic cough 4. The vast majority of patients are heavy smokers (90%) with an average smoking history of 18 pack-years. [radiopaedia.org]
Respiratoric
- Cough
Our patient was a 56-year-old male, heavy smoker, with bilateral lung infiltrations of unknown etiology and several months of discomfort in the form of dry cough and shortness of breath. [ncbi.nlm.nih.gov]
Over-the-counter medications can help relieve some symptoms, such as the dry coughing. There is no current cure for desquamative interstitial pneumonia. [wisegeek.com]
Desquamative interstitial pneumonia manifests with gradually increasing dyspnea and nonproductive cough. [msdmanuals.com]
- Dyspnea
A 45-year-old male smoker heavily used a waterproofing spray gas, and presented with chills and fever that was followed by progressive dyspnea. Because steroid pulse therapy did not improve his symptoms, he was referred to our hospital. [ncbi.nlm.nih.gov]
Desquamative interstitial pneumonia manifests with gradually increasing dyspnea and nonproductive cough. [msdmanuals.com]
- Rales
Two patients with diffuse interstitial lung disease after long-term nitrofurantoin therapy were characterized clinically by exertional dyspnea and basilar rales, roentgenographically by diffuse interstitial infiltrate and physiologically by a restrictive [ncbi.nlm.nih.gov]
[…] loss of volume is characteristic of either UIP or scleroderma Clinically Symptoms include SOB, non-productive cough and fatigue Clubbing of the fingers is very common (85%) Cyanosis and pulmonary hypertension usually occur late in the disease “Velcro” rales [learningradiology.com]
While rales on auscultation may be heard in each of the two conditions, digital clubbing is more common in DIP. Approximately 60% of DIP patients are found to have rales on auscultation on physical examination. [spandidos-publications.com]
- Pulmonary Disorder
If confirmed, this observation would add DIP to the list of pulmonary disorders that are amenable to the beneficial antiinflammatory effects of macrolides. [ncbi.nlm.nih.gov]
The presence of DIP-like reactions around a variety of spaces that occupy pulmonary lesions and of some diffuse pulmonary disorders further limit the diagnostic application of small-tissue biopsies: this mandates close radiographic correlation with findings [err.ersjournals.com]
- Persistent Cough
Case 1 (above): 68 year old man, ex-smoker (60 pack-years), presented with persistent cough - Biopsy from S5 Images hosted on other servers: Trichrome staining H&E and IHC of CD68 Virtual slides Images hosted on other servers: Dr. [pathologyoutlines.com]
The most frequent presenting features of DIP are the onset of breathlessness during exercise and a persistent cough that is not always productive of sputum [ 1, 3, 5, 6 ]. [err.ersjournals.com]
Workup
His entire workup failed to demonstrate cystic fibrosis, or any infectious or immune-related diseases. Chest imaging and clinical picture suggested parenchymal lung disease. [ncbi.nlm.nih.gov]
It is possible that bronchiolocentric interstitial pneumonia represents a form of chronic hypersensitivity pneumonitis for which the inhalational stimulus has not been identified despite our extensive workup for this condition. [nature.com]
X-Ray
- Pulmonary Infiltrate
Since DIP is treatable, HCV patients with pulmonary infiltrates should be thoroughly investigated for this disorder. [ncbi.nlm.nih.gov]
Treatment
Eleven patients with UIP and 11 with DIP received treatment between the initial and follow-up CT scans. [ncbi.nlm.nih.gov]
Prognosis
It is important to recognize that desquamative interstitial pneumonia has distinctive clinical features, prognosis, and response to treatment. [histopathology-india.net]
Hazy densities in a peripheral distribution on CT may indicate active IPF associated with a good prognosis. [ncbi.nlm.nih.gov]
Treatment and prognosis With smoking cessation and corticosteroid therapy, the prognosis is good. The overall prognosis of has been described as being significantly better than that of fibrotic NSIP 11. [radiopaedia.org]
Etiology
Our patient was a 56-year-old male, heavy smoker, with bilateral lung infiltrations of unknown etiology and several months of discomfort in the form of dry cough and shortness of breath. [ncbi.nlm.nih.gov]
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. [icd10coded.com]
Carrington et al ( 22 ) suggested marijuana use as an etiological factor. [spandidos-publications.com]
The pathogenesis and etiology of DIP are not clear. [histopathology-india.net]
Epidemiology
The epidemiological and clinical features of DIP are summarised in table 1. Table 1. [err.ersjournals.com]
Based on the Bernalillo County, NM, USA registry data published in 1994, the overall estimated incidence is approximately 30 cases per 100,000 persons per year. [2] Rates of interstitial lung disease are somewhat higher in men than in women, and the epidemiology [emedicine.medscape.com]
Global or national epidemiological data are usually for idiopathic pulmonary fibrosis (IPF), which is the most common form of IIPs. [spandidos-publications.com]
Other causes of the usual interstitial pneumonia pattern include domestic and occupational environmental exposures, connective tissue disease, and drug toxicity. 28 An epidemiologic association between smoking and usual interstitial pneumonia is well [mdedge.com]
Pathophysiology
Introduction Definition restricted lung expansion results in reduced lung volumes (TLC and FVC) Pathophysiology poor breathing mechanics with normal lung function muscle weakness polio and myasthenia gravis chest wall limitation kyphosis, scoliosis, and [medbullets.com]
[…] macrophage pneumonia”, it is still officially called “desquamative interstitial pneumonia” ( Am J Respir Crit Care Med 2002;165:277 ) ICD coding Desquamative interstitial pneumonia: J84.117 Sites Bilateral (or sometimes unilateral) lobes of the lung Pathophysiology [pathologyoutlines.com]
Prevention
Getting a flu shot every year can help prevent both the flu and pneumonia. In addition, pneumococcal bacteria can cause minor problems such as ear infections. [cedars-sinai.edu]
Can interstitial lung disease be prevented? Interstitial lung disease can be prevented only to the extent that its individual causes may be prevented. [rxlist.com]
[…] resting hypoxemia in patients with interstitial lung disease is V/Q mismatch, with DLCO defect contributing to hypoxemia with activity increased expiratory flow rates due to increased radial traction (result of increased elastic recoil) on airway walls prevents [medbullets.com]
[…] pneumonia or Acute Respiratory Distress Syndrome (ARDS)) based on clinical or radiological evidence of consolidation and ar لا يمكن السماح لها بالدخول في رأسك en There is growing consensus on a core set of family care practices that address five common, preventable [ar.glosbe.com]