More than 60% of the adult population is estimated to suffer from a deviated nasal septum according to certain reports [1], but the clinical presentation varies depending on the location and severity of nasal septum deviation. Individuals may often be asymptomatic, but the most common signs include epistaxis, increased nasal crusting, altered nasal respiration and the necessity for mouth breathing due to obstruction of the nasal canal, and chronic or recurrent sinusitis, which is frequently encountered among patients in whom deviation causes obstruction of the ostium of the paranasal sinus [2] [3] [4]. Repetitive sneezing, snoring and sleep apnea are also reported, while less common symptoms include facial pain, variable loss of olfaction and headaches [3]. Recent trauma to the nose and face is the key risk factor for deviation, but congenital causes may be responsible as well. Neonates and infants commonly develop deviation of the nasal septum due to trauma during vaginal delivery [2], and in this population, poor feeding and choking due to the presence of food in the respiratory tract are reported in the case of a severe deviation, in addition to nasal obstruction and epistaxis [2]. Various anatomical anomalies, such as increased anterior facial height, mandible with increased overjet and constricted transverse maxillary dimension and a retrognathic maxilla have been documented in patients suffering from nasal septum deviation [4].

• Snoring

  Some patients had associated pre-operative symptoms of snoring (57.3%), headache (48.0%), rhinorrhoea (38.7%), sneezing (30.7%), hyposmia (30.7%) and epistaxis (21.3%). [ncbi.nlm.nih.gov]

  […] mostly without their knowledge.[1] Signs and symptoms[edit] Only more severe cases of a deviated septum will cause symptoms of difficulty breathing and require treatment.[1] Symptoms of a deviated septum include infections of the sinus and sleep apnea, snoring [en.wikipedia.org]

  A deviated nasal septum can cause sinus infections, sleep apnea, snoring, sneezing attacks, facial pain, nosebleeds, breathing difficulties and a slight to serious loss of sense of smell. [respifacile.com]

  A severely deviated nasal septum can block one side of your nose and reduce airflow, which can cause difficulty breathing, snoring, recurrent sinus infections, crusting or nosebleeds. [ent-sd.com]

  However, indirectly, there is a link between nasal septum deviation and sleep breathing disorders, including snoring and sleep apnea. [sleep-apnea-guide.com]

• Mitral Valve Prolapse

  Abstract Any abnormality of collagen may affect the tissues with higher collagen content, e.g., joints, heart valves, and great arteries. Mitral valve prolapse (MVP) is a characteristic of generalized collagen abnormality. [ncbi.nlm.nih.gov]

• Mouth Breathing

  This may lead to obstruction of nasal breathing to one or both sides. Other symptoms of a deviated septum include nasal drainage, nosebleeds, mouth breathing, and facial pressure. A crooked or deviated septum is not usually caused by an injury. [nw-ent.com]

  Individuals may often be asymptomatic, but the most common signs include epistaxis, increased nasal crusting, altered nasal respiration and the necessity for mouth breathing due to obstruction of the nasal canal, and chronic or recurrent sinusitis, which [symptoma.com]

  Chronic mouth breathing may worsen snoring or lead to dry mouth and/or sore throat. Usually nasal obstruction is worse on a particular side but may vary from side to side due to other factors, such as colds or allergies. [entallergy1.com]

  If the blockage is severe, it may force mouth-breathing at night, which can worsen sleep disorders. [entnet.org]

  A deviated septum and swelling of the intranasal tissues can negatively affect a patient’s quality of sleep and can lead to dry mouth due to chronic mouth breathing. [pacificneuroscienceinstitute.org]

• Bony Swelling

  The turbinates are bony swellings on the outer walls of the nasal cavities. Both the nasal septum and turbinates are covered with a delicate mucosal tissue that regularly swells to control airflow in the nose. [nycfacemd.com]

• Epistaxis

  Some patients had associated pre-operative symptoms of snoring (57.3%), headache (48.0%), rhinorrhoea (38.7%), sneezing (30.7%), hyposmia (30.7%) and epistaxis (21.3%). [ncbi.nlm.nih.gov]

  A deviated nasal septum is quite common in the general population and is often asymptomatic, but some individuals can develop chronic nasal obstruction, recurrent epistaxis and are predisposed to chronic sinusitis. [symptoma.com]

  Symptomatic patients can present with unilateral nasal obstruction or less commonly epistaxis, obstructive sinusitis, and/or pain/pressure symptoms 4. Etiology Nasal septum deviation can be congenital or acquired. [radiopaedia.org]

  It may also predispose to repeated epistaxis from the vessels stretched on its convex surface. 5. Thickening of Nasal Septum It may be due to organized haematoma or overriding of dislocated septal cartilage fragments. 4. [slideshare.net]

  Symptomatic septal deviation causes nasal obstruction and predisposes the patient to sinusitis (particularly if the deviation obstructs the ostium of a paranasal sinus) and to epistaxis due to drying air currents. [msdmanuals.com]

The diagnosis rests on suspecting a deviated nasal septum based on signs and symptoms that are reported by the patient, which is why a detailed patient history can often provide sufficient clues to develop clinical suspicion. Information about recent trauma, chronicity of symptoms, as well as their severity, can be helpful. A thorough physical examination comprised of a full ear, nose, and throat evaluation should follow, and anterior rhinoscopy or nasal endoscopy can confirm the diagnosis, as they provide a direct view into the nasal cavity [2]. Additional procedures have been proposed in the workup, including acoustic rhinometry (evaluation of the nasal cavity by means of acoustic reflection), rhinomanometry (a procedure that measures the resistance of the nasal cavity) and nasal spectral sound analysis, but their specificity and sensitivity remain to be solidified in regular practice [2]. More advanced imaging studies, such as computed tomography (CT), may be useful for preoperative assessment and determination of potential anatomical anomalies, but they are not superior to the standard physical examination when it comes to detecting a deviated nasal septum [5].

• Lymphocytic Infiltrate

  This study determined significantly higher rate of squamous metaplasia and lymphocytic infiltration in septal mucosa on concave side when compared with convex side. [ncbi.nlm.nih.gov]

Deviated nasal septum treatment options A deviated nasal septum only requires treatment if it is causing nasal obstruction in one or both sides of the nose. [henryford.com]

Treatment Treatment of a deviated septum is based on the patient's symptoms. [healthcentral.com]

Treatment at Penn Treatments include decongestants, antihistamines, nasal steroids, use of an adhesive strip to open nasal passages, and surgery. [pennmedicine.org]

Medical treatments for nasal obstruction Medical treatments such as nasal steroid sprays or decongestant sprays work to shrink the inferior turbinate which is adjacent to the septum. [houstonadvancedsinus.com]

Treatment and prognosis If medical management fails, the most common surgical procedure performed is septoplasty 4.5. Promoted articles (advertising) [radiopaedia.org]

Prognosis Surgical repair is curative and carries little risk. Chronic infection can be painful and lead to complications until it is resolved. If there is continued obstruction, the infection will very likely return. [medical-dictionary.thefreedictionary.com]

Prognosis In the most cases, surgery is successful. However, a small percentage of patients choose to have a second surgery for cosmetic reasons or to improve airflow. [drugs.com]

Etiology Nasal septum deviation can be congenital or acquired. The most common acquired cause is trauma from motor vehicle collisions, sports-related injuries, and altercations. [radiopaedia.org]

Our data may support a noncongenital etiology for nasal septal deviation. [shahfacialplastics.com]

Deviated nasal septum incidence and etiology. Annals Otol Rhinol Laryngol. 1978;87(3):3-20.‏ van der Veken PJ1, Clement PA, Buisseret T, Desprechins B, Kaufman L, et al. [ijorl.com]

The most frequent etiology of NSD is nasal trauma, what occurs in men more often. The percentage of volunteers with NSD and nasal obstruction was 60%, for both men and women. [arquivosdeorl.org.br]

Etiology Any trauma and errors in the development of nasal septum are the two important factors causing DNS. 1) Trauma 2) Developmental Defects There may be some racial factors as well as hereditary factors. 3) Racial Factors 4) Hereditary Factors 1) [slideshare.net]

Stamler J, Berkson DM, Dyer A, Lepper MH, Lindberg HA, Paul O et al (1975) Relationship of multiple variables to blood pressure-findings from four Chicago epidemiologic studies. [link.springer.com]

Mohebbi et al. in their study ‘An epidemiologic study of factors associated with nasal septum deviation by computed tomography scan: a cross sectional study’ published in 2012 found no relationship between the severity of sinusitis, osteomeatal involvement [article.sapub.org]

Definition of overactive bladder and epidemiology of urinary incontinence. Urology 1997;50:4-14. [ Crossref ] [ PubMed ] Samuelsson EC, Victor FT, Tibblin G, et al. [doi.org]

Due to changes in pathophysiology the patient is more susceptible to chronic rhinitis/rhinosinusitis. KEYWORDS: Chronic inflammation; Microscopy; Nasal mucosa; Nasal septum; Squamous metaplasia [ncbi.nlm.nih.gov]

Figure showing unusual growth patterns between nasal septum and palate causing buckling of nasal septum Pathophysiology: Deformity of nasal septum may be classified into: 1. Spurs 2. Deviations 3. [drtbalu.com]

However, the main pathophysiology of these chronic conditions is poorly described and seems to be multifactorial. [cyberleninka.org]

Packing does not prevent bleeding but will prevent topical decongestants from reaching bleeding sites. Packing also keeps nasal saline from cleaning the inside of the nose. [nycfacemd.com]

Medications such as antihistamines, decongestants, and nasal steroid sprays can reduce congestion and inflammation to help prevent a runny nose and postnasal drip. [eoent.com]

Though some surgeons still use packing to prevent postoperative bleeding, the National Institute of Health states that, “Nasal packing has several risks for patients and septoplasty can be safely performed without [it].” [rhinoplasty.com]

1. Mohebbi A, Ahmadi A, Etemadi M, Safdarian M, Ghourchian S. An epidemiologic study of factors associated with nasal septum deviation by computed tomography scan: a cross sectional study. BMC Ear, Nose, and Throat Disord. 2012;12:15.
2. Aziz T, Biron VL, Ansari K, Flores-Mir C. Measurement tools for the diagnosis of nasal septal deviation: a systematic review. J Otolaryngol Head Neck Surg. 2014;43(1):11.
3. Porter RS, Kaplan JL. Merck Manual of Diagnosis and Therapy. 19th Edition. Merck Sharp & Dohme Corp. Whitehouse Station, N.J; 2011.
4. Aziz T, Biron VL, Ansari K, Flores-Mir C. Measurement tools for the diagnosis of nasal septal deviation: a systematic review. J Otolaryngol Head Neck Surg. 2014;43(1):11.
5. Sedaghat AR, Kieff DA, Bergmark RW, Cunnane ME, Busaba NY. Radiographic evaluation of nasal septal deviation from computed tomography correlates poorly with physical exam findings. Int Forum Allergy Rhinol. 2015;5(3):258-262.