Presentation
// Taber's Cyclopedic Medical Dictionary (2009);2009, Issue 21, p176 A definition of the term "Argyll Robertson pupil," which pertains to a symptom present in paralysis and locomotor ataxia, is presented. [connection.ebscohost.com]
Small fiber modalities are involved earlier than large fiber deficits (burning; lancinating pain; deep muscle ache); later loss of vibration and proprioception in the legs-if severe may present as diabetic pseudo-tabes. [neurodiffdx.com]
PowerPoint Presentation: Small epidermal nerve fibers stain positive for the neuronal antigen protein gene product 9.5 (PGP 9.5). Treatment : Strict glucose control from the time of diagnosis of DM is the most important aspect of treatment. [authorstream.com]
Presentation on theme: "Diabetic Peripheral Neuropathies"— Presentation transcript: 1 Diabetic Peripheral Neuropathies A clinical and electro physiologic understanding 2 Diabetic Neuropathy General: Prevalence – 30 to 50% DiabCare Asia Statistics – 37% [slideplayer.com]
Entire Body System
- Falling
Insulin requirements fall to prepregnancy levels within the first 24 hours after delivery. The order in which obese people with type 2 diabetes eat their food can affect their blood sugar levels a small study suggests. [gospelblues.eu]
[…] acute symptoms indicating CHOA onset and progress (Fig. 15.8 ) Fig. 15.8 Foot in the CHOA acute stage. ( a ) Acute CHOA in the region of the ankle with a marked swelling of soft structures; ( b ) involvement of the left foot with swelling and subsequent fall [musculoskeletalkey.com]
Plasma insulin levels fall, and insulin secretory responses to glucose become impaired during surgery. 17 – 19 The mechanism of the impaired β-cell responsiveness during surgery is unclear, and the defect is poorly correlated with ambient intraoperative [spectrum.diabetesjournals.org]
[…] exact onset of the Charcot spine is notknown but it was not present immediately afterthe accident when she fell on her back in 1945 .That some changes were taking place and someinjury had resulted can be deduced from thecontinual pain subsequent to this fall [docslide.com.br]
Plasma insulin levels fall, and insulin secretory responses to glucose become impaired during surgery. (17-19) The mechanism of the impaired [beta]-cell responsiveness during surgery is unclear, and the defect is poorly correlated with ambient intraoperative [go.galegroup.com]
Skin
- Foot Ulcer
Young MJ, Manes C, Boulton AJM: Vibration perception threshold predicts foot ulceration. Diabet Med 1992;9(suppl 2):542. [karger.com]
Annual comprehensive foot examination should be done in all diabetic patients to identify risk conditions suggestive of ulcers and amputations But for patients with insensate feet, foot deformities, or a history of foot ulcers, feet examination should [specialty.mims.com]
DM 2 w diabetic neuropathic foot ulcer DM 2 w diabetic neuropathic heel and midfoot ulcer DM 2 w diabetic neuropathic toe ulcer DM 2 w diabetic neuropathy DM 2 W diabetic peripheral neuropathy DM 2 w diabetic peripheral sensory neuropathy DM 2 W diabetic [icd9data.com]
DM 2 w diabetic neuropathic foot ulcer, DM 2 w diabetic neuropathic heel and midfoot ulcer, DM 2 w diabetic neuropathic toe ulcer, DM 2 w diabetic neuropathy, DM 2 W diabetic peripheral neuropathy, DM 2 w diabetic peripheral sensory neuropathy, DM 2 [healthresearchfunding.org]
Strongly endorsed is the use of the 10-g monofilaments for screening of feet to detect sensation loss, with the goal of improving diabetic management and prevention of foot ulcers and neurogenic arthropathy. [paperity.org]
Musculoskeletal
- Neuropathic Arthropathy
[…] ankle ulcer due to type 2 diabetes mellitus, neuropathic arthropathy due to type 2 diabetes mellitus, neuropathic foot ulcer due to type 2 diabetes mellitus, neuropathic midfoot AND/OR heel ulcer due to type 2 diabetes mellitus, neuropathic toe ulcer [healthresearchfunding.org]
arthropathy Unlike syphilis diabetic neuroapthic arthropathy involves small joints of feet Diabetic pseudotabes Diabetic lumbosacral radiculoplexus neuropathy (Bruns-Garland syndrome): Clinical features Males more frequently affected than females Pain [authorstream.com]
- Back Pain
[…] narrowed Subluxation of the FACET JOINTS Spondylolisthesis - slippage of one vertebra over another Boney Changes: Clinical Features of Bony Changes Clinical Features of Bony Changes: Multiple root involvement Widespread arthritic changes Long standing low back [quizlet.com]
Urogenital
- Urinary Incontinence
Faecal And Urinary Incontinence The expression of TRPV1 in the bladder is, however, not restricted to afferent nerves urothelium, detrusor muscle and fibroblasts also express TRPV1 in the human bladder 140. [europeanmedical.info]
Neurologic
- Decreased Proprioception
When these manifestations coexist with decreased proprioception in the feet, "pseudotabetic" gait may occur. diabetic tabes An obsolete term for diabetic neuropathy. See also: tabes [medical-dictionary.thefreedictionary.com]
- Abnormal Gait
DANIL HAMMOUDI.MD SINOE MEDICAL ASSOCIATION DETAILS ARE COMING FOR EACH OF THESE SYNDROME ABNORMAL GAIT (excluding orthopaedic causes) hemiplegia (cerebrovascular accident involving motor cortex or pyramidal tract) parkinsonism (shuffling / festinant) [sinoemedicalassociation.org]
Treatment
Neurosyphilis: Diagnosis and Response to Treatment. Musher, Daniel M. // Clinical Infectious Diseases;10/1/2008, Vol. 47 Issue 7, p900 The author reflects on the article about the serological response to treatment of neurosyphilis. [connection.ebscohost.com]
Uremic Polyneuropathy: Cause And Treatment Cause 300-2000 molecular weight toxins Treatment: symptomatic renal transplant Second most common cause of neuropathy Pathogenesis direct toxic effect nutritional (B1, B3, B6, B12, folic acid, zinc) Symmetric [quizlet.com]
[…] and hyperintensive treatment, the treatment of end-stage diabetic nephropathy, and combined pancreas and kidney transplantation. 2005), DD genotype of ACE gene is a predisposing factor for chronic kidney disease (CKD) terminating nephrotic syndrome in [freethesaurus.com]
Emerging Treatments in Diabetic Wound Care. [opther.eu]
GIOSTAR provide Stem Cell Treatment as a Potential Therapy for Diabetes Autism Osteoarthritis & More Diseases in India USA UAE & UK. type 2 diabetes impotence treatment Current California Multiple Subject Teaching Credential Letter of Interest Resume [flutekids.eu]
Prognosis
Argyll Robertson Pupil Prognosis Most sufferers do well after treatment. The outcome is poorest for patients who suffer permanent nerve or cardiac damage. Life expectancy is poor due to inability to reverse these symptoms of such advanced disease. [patienthelp.org]
H&P( Most Important) Lumbar puncture EMG- Great for determining Myelination Serology Toxicology For This( Protein goes up, cell count is normal Guillain Bare Syndrome/ Treatment: Treatment: Supportive care Plasmapheresis IV IgG No role for steroids Prognosis [quizlet.com]
[…] intercostal nerve trunk involvement Focal contact hyperesthaesiae in the same area as the pain Truncal Neuropathy PowerPoint Presentation: Focal anterior abdominal wall weakness may be evident Associated weight loss in some cases may be profound Good prognosis [authorstream.com]
Causes and prognosis in 4,278 cases of paralysis of the oculomotor, trochlear, and abducens cranial nerves. Am J Ophthalmol 1992; 113: 489–496. Google Scholar | Crossref | Medline | ISI 95. Casellini, CM, Vinik, AI. [journals.sagepub.com]
Although severe and tenacious, the pain of proximal motor neuropathy has a good prognosis. Concurrent distal sensory polyneuropathy is frequently present. [oncohemakey.com]
Etiology
The etiologies of focal myopathies include traumatic (associated with insulin injection injury) and vascular (related to thigh muscle infarction). [mitchmedical.us]
[…] large fibers Autonomic neuropathies Small-fiber neuropathies 3 Focal/multifocal neuropathies Cranial neuropathies Thoracoabdominal radiculopathies Focal limb neuropathies Proximal neuropathies Compression and entrapment neuropathies The most important etiologic [oncohemakey.com]
Although these theories are still generally accepted, it has been demonstrated that also other etiological factors participating in CHOA development and manifestation have to be taken into account. [musculoskeletalkey.com]
Epidemiology
Five general areas are addressed in the 36 chapters: descriptive epidemiology of diabetes in the U.S., including prevalence, incidence, sociodemographic & metabolic characteristics, risk factors for developing diabetes, & mortality. [books.google.de]
Nephrology, pathology, internal medicine, diabetology, and other specialists from Germany, the US, and Lebanon address the relationship between the kidney and diabetes and cover the epidemiology, history, pathophysiology, histology, genetic risk factors [freethesaurus.com]
Williams DRR: The size of the problem: Epidemiological and economic aspects of foot problems in diabetes; in Boulton AJM, Connor H, Cavanagh PR (eds): The Foot in Diabetes, ed 2. Chichester, Wiley, 1994, pp 15–24. [karger.com]
"Blood Pressure" [SH] (epidemiology AND humans) [SH] SI Secondary Source ID The SI field identifies secondary source databanks and accession numbers, e.g., GenBank, GEO, PubChem, ClinicalTrials.gov, ISRCTN. [biomedsearch.com]
Painful diabetic neuropathy: epidemiology, natural history, early diagnosis, and treatment options. Pain Med 2008; 9: 660–674. Google Scholar | Crossref | Medline | ISI 12. Obrosova, IG. [journals.sagepub.com]
Pathophysiology
Regarding patients with nerve infarction, the onset is acute and painful, the pathophysiology reflects axon loss, and recovery is often slow and suboptimal. [mitchmedical.us]
Comparative renal pathophysiology relevant to IDDM and NIDDM patients. Diab Metab Rev 1988;4:453-483. 8. Cunha-Vaz JG. Studies on the pathophysiology of diabetic retinopathy. The blood-retinal barrier in diabetes. Diabetes 1983;32:20-27. 9. [diabetesaid.com]
Nephrology, pathology, internal medicine, diabetology, and other specialists from Germany, the US, and Lebanon address the relationship between the kidney and diabetes and cover the epidemiology, history, pathophysiology, histology, genetic risk factors [freethesaurus.com]
Loss of myelinated nerve fibers Segmental remyelination and demyelination Basement membranes of intraneural capillaries are thickened and duplicated Areas of perivascular inflammation ( said,dyck et al) Biochemical mechanisms Pathology and pathophysiology [authorstream.com]
[…] non noxious stimuli with sensory deficits, anoxexia, weight loss, depression Generally recovers Hyperglycemic Neuropathy Widespread parasthesias in newly diagnosed cases, after recovery from ketosis Improve rapidly with control, could have a different pathophysiologic [slideserve.com]
Prevention
[…] readings management weight gestational prevention review mellitus studies Natural Treatment for Herpes. [opther.eu]
/Avoidable - 67% Emergent - ED Care Needed - Not Preventable/Avoidable - 0% Primary diagnosis of injury 0% Primary diagnosis of mental health problems 0% Primary diagnosis of substance abuse 0% Primary diagnosis of Alcohol 0% Unclassified 0% We Could [medicbind.com]
Controlling your blood sugar can help prevent nerve problems, or keep them from getting worse. Treatment may include pain relief and other medicines. [icdlist.com]
Diabetic neuritis is not a new condition, yet little progress seems to have been made in its prevention or cure. Although previous to 1864 symptoms suggestive of the degeneration of nerves [jamanetwork.com]