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Diabetic Pseudotabes


Presentation

  • The fact that the incidence of diabetes is very high, at present 1 %-2 % of the population is affected and their number is gradually increasing - dis plays the timeliness of this subject.[books.google.de]
  • . // Taber's Cyclopedic Medical Dictionary (2009);2009, Issue 21, p176 A definition of the term "Argyll Robertson pupil," which pertains to a symptom present in paralysis and locomotor ataxia, is presented.[connection.ebscohost.com]
  • Small fiber modalities are involved earlier than large fiber deficits (burning; lancinating pain; deep muscle ache); later loss of vibration and proprioception in the legs-if severe may present as diabetic pseudo-tabes.[neurodiffdx.com]
  • PowerPoint Presentation: Small epidermal nerve fibers stain positive for the neuronal antigen protein gene product 9.5 (PGP 9.5). Treatment : Strict glucose control from the time of diagnosis of DM is the most important aspect of treatment.[authorstream.com]
Falling
  • Insulin requirements fall to prepregnancy levels within the first 24 hours after delivery. The order in which obese people with type 2 diabetes eat their food can affect their blood sugar levels a small study suggests.[gospelblues.eu]
  • Plasma insulin levels fall, and insulin secretory responses to glucose become impaired during surgery. 17 – 19 The mechanism of the impaired β-cell responsiveness during surgery is unclear, and the defect is poorly correlated with ambient intraoperative[spectrum.diabetesjournals.org]
  • Plasma insulin levels fall, and insulin secretory responses to glucose become impaired during surgery. (17-19) The mechanism of the impaired [beta]-cell responsiveness during surgery is unclear, and the defect is poorly correlated with ambient intraoperative[go.galegroup.com]
Disability
  • Complications of diabetes (disability, vision disorders, heart disease, infection, etc.); medical care for diabetes; economic aspects, including health insurance & health care costs; & diabetes in special populations, including Blacks, Hispanics, Asian[books.google.de]
  • Stage III - Disabling neuropathy - Disabling symptoms and 2 or more functional abnormalities. Vascular hypoxic changes are manifested as 1. Basement membrane thickening & reduplication 2. Endothelial cell swelling and pericyte degeneration 3.[diabetescare.page.tl]
  • Muscle Nerve 27 : 202 –210, 2003 Losseff NA, Webb SL, O’Riordan JI, Page R, Wang L, Barker GJ, Tofts PS, McDonald WI, Miller DH, Thompson AJ: Spinal cord atrophy and disability in multiple sclerosis: a new reproducible and sensitive MRI method with potential[care.diabetesjournals.org]
Chronic Fatigue Syndrome
  • These include criteria for the diagnosis of multiple sclerosis, dementia of Lewy-body type, frontal lobe dementias, chronic fatigue syndrome, and inflammatory neuropathies.[books.google.com]
Vision Disorder
  • Complications of diabetes (disability, vision disorders, heart disease, infection, etc.); medical care for diabetes; economic aspects, including health insurance & health care costs; & diabetes in special populations, including Blacks, Hispanics, Asian[books.google.de]
Foot Ulcer
  • Strongly endorsed is the use of the 10-g monofilaments for screening of feet to detect sensation loss, with the goal of improving diabetic management and prevention of foot ulcers and neurogenic arthropathy.[paperity.org]
  • ulcer due to type 2 diabetes mellitus Neuropathic midfoot AND/OR heel ulcer due to type 2 diabetes mellitus Neuropathic toe ulcer due to type 2 diabetes mellitus Neuropathy due to type 2 diabetes mellitus Peripheral autonomic neuropathy due to diabetes[icd9data.com]
  • ulcer, DM 2 w diabetic neuropathic heel and midfoot ulcer, DM 2 w diabetic neuropathic toe ulcer, DM 2 w diabetic neuropathy, DM 2 W diabetic peripheral neuropathy, DM 2 w diabetic peripheral sensory neuropathy, DM 2 W diabetic polyneuropathy, DM 2 with[healthresearchfunding.org]
  • ulcers suggestive of severe sensory neuropathy Diabetic Peripheral Neuropathy - 10 Severe painful neuropathy causes depression Diabetic neuropathic cachexias Severe exacerbations of burning pains, allodynia ie excessive pain sensation to non noxious[slideserve.com]
Neurogenic Arthropathy
  • Strongly endorsed is the use of the 10-g monofilaments for screening of feet to detect sensation loss, with the goal of improving diabetic management and prevention of foot ulcers and neurogenic arthropathy.[paperity.org]
  • Use additional code to identify manifestation, as: • diabetic: • amyotrophy ( 353.5 ) • gastroparalysis ( 536.3 ) • gastroparesis ( 536.3 ) • mononeuropathy ( 354.0-355.9 ) • neurogenic arthropathy ( 713.5 ) • peripheral autonomic neuropathy ( 337.1 )[coding-pro.com]
Back Pain
  • pain Differences Between Disc Herniations and Boney formations Disc Herniations: Age( UNDER 40,) Boney Change( OVER 50) Backache: Disc( Short duration), Boney change( Long Duration) Straight leg: Disc( Limited), Boney (Often Not affected) Number of Segments[quizlet.com]
Uremia
  • Orthostatic hypotension and sexual dysfunction Mechano dynamic and static allodynia; hyperalgesia are common Cramps of the feet and thigh (neurogenic cramps) Differential diagnosis of burning feet DM HIV (Distal neuropathy) INH Pyridoxine excess or deficiency Uremia[neurodiffdx.com]
Decreased Proprioception
  • When these manifestations coexist with decreased proprioception in the feet, "pseudotabetic" gait may occur. diabetic tabes An obsolete term for diabetic neuropathy. See also: tabes[medical-dictionary.thefreedictionary.com]
Cerebellar Disease
  • Entries on cerebellar diseases, peripheral neuropathies, various dementias, diagnostic tests (both clinical and laboratory), forms of cerebral edema, dissociative signs and syndromes - all these and many more have been added, expanded, updated or clarified[books.google.com]

Treatment

  • However, it is particularly important because of the good re sults of appropriate treatment and the unfortunate consequences should the diagnosis be missed.[books.google.com]
  • He is an expert in the pathogenesis, assessment and treatment of diabetic neuropathy and has been a co-editor for three books, co-authored over 30 book chapters and published ( 130 peer reviewed papers) and presented ( 500 national and international presentations[books.google.com]
  • Neurosyphilis: Diagnosis and Response to Treatment. Musher, Daniel M. // Clinical Infectious Diseases;10/1/2008, Vol. 47 Issue 7, p900 The author reflects on the article about the serological response to treatment of neurosyphilis.[connection.ebscohost.com]
  • Uremic Polyneuropathy: Cause And Treatment Cause 300-2000 molecular weight toxins Treatment: symptomatic renal transplant Second most common cause of neuropathy Pathogenesis direct toxic effect nutritional (B1, B3, B6, B12, folic acid, zinc) Symmetric[quizlet.com]

Prognosis

  • Argyll Robertson Pupil Prognosis Most sufferers do well after treatment. The outcome is poorest for patients who suffer permanent nerve or cardiac damage. Life expectancy is poor due to inability to reverse these symptoms of such advanced disease.[patienthelp.org]
  • H&P( Most Important) Lumbar puncture EMG- Great for determining Myelination Serology Toxicology For This( Protein goes up, cell count is normal Guillain Bare Syndrome/ Treatment: Treatment: Supportive care Plasmapheresis IV IgG No role for steroids Prognosis[quizlet.com]
  • […] intercostal nerve trunk involvement Focal contact hyperesthaesiae in the same area as the pain Truncal Neuropathy PowerPoint Presentation: Focal anterior abdominal wall weakness may be evident Associated weight loss in some cases may be profound Good prognosis[authorstream.com]
  • Causes and prognosis in 4,278 cases of paralysis of the oculomotor, trochlear, and abducens cranial nerves . Am J Ophthalmol 1992 ; 113: 489 – 496 . Google Scholar Medline ISI 95. Casellini, CM, Vinik, AI.[journals.sagepub.com]

Etiology

  • The etiologies of focal myopathies include traumatic (associated with insulin injection injury) and vascular (related to thigh muscle infarction).[mitchmedical.us]

Epidemiology

  • Five general areas are addressed in the 36 chapters: descriptive epidemiology of diabetes in the U.S., including prevalence, incidence, sociodemographic & metabolic characteristics, risk factors for developing diabetes, & mortality.[books.google.de]
  • Nephrology, pathology, internal medicine, diabetology, and other specialists from Germany, the US, and Lebanon address the relationship between the kidney and diabetes and cover the epidemiology, history, pathophysiology, histology, genetic risk factors[freethesaurus.com]
  • Painful diabetic neuropathy: epidemiology, natural history, early diagnosis, and treatment options . Pain Med 2008 ; 9: 660 – 674 . Google Scholar Medline ISI 12. Obrosova, IG .[journals.sagepub.com]
  • Argyll Robertson Pupil Epidemiology This is a rare disease and occurs only sometimes in advanced cases of syphilis and other neurological disorders [ 3 ]. As it is associated with syphilis in most cases, it is uncommon in developing countries.[patienthelp.org]
  • There is increasing evidence from epidemiological to nerve biopsy and in vivo studies in humans for the involvement of microvascular factors in the pathogenesis of axonal loss in the peripheral nerve ( 2 , 27 – 31 ).[care.diabetesjournals.org]
Sex distribution
Age distribution

Pathophysiology

  • Nephrology, pathology, internal medicine, diabetology, and other specialists from Germany, the US, and Lebanon address the relationship between the kidney and diabetes and cover the epidemiology, history, pathophysiology, histology, genetic risk factors[freethesaurus.com]
  • Regarding patients with nerve infarction, the onset is acute and painful, the pathophysiology reflects axon loss, and recovery is often slow and suboptimal.[mitchmedical.us]
  • : Loss of myelinated nerve fibers Segmental remyelination and demyelination Basement membranes of intraneural capillaries are thickened and duplicated Areas of perivascular inflammation ( said,dyck et al) Biochemical mechanisms Pathology and pathophysiology[authorstream.com]
  • […] non noxious stimuli with sensory deficits, anoxexia, weight loss, depression Generally recovers Hyperglycemic Neuropathy Widespread parasthesias in newly diagnosed cases, after recovery from ketosis Improve rapidly with control, could have a different pathophysiologic[slideserve.com]
  • […] noxious stimuli with sensory deficits, anoxexia, weight loss, depression Generally recovers 13 Hyperglycemic Neuropathy Widespread parasthesias in newly diagnosed cases, after recovery from ketosis Improve rapidly with control, could have a different pathophysiologic[slideplayer.com]

Prevention

  • Avoidable - 67% Emergent - ED Care Needed - Not Preventable/Avoidable - 0% Primary diagnosis of injury 0% Primary diagnosis of mental health problems 0% Primary diagnosis of substance abuse 0% Primary diagnosis of Alcohol 0% Unclassified 0% We Could[medicbind.com]
  • Controlling your blood sugar can help prevent nerve problems, or keep them from getting worse. Treatment may include pain relief and other medicines.[icdlist.com]
  • Strongly endorsed is the use of the 10-g monofilaments for screening of feet to detect sensation loss, with the goal of improving diabetic management and prevention of foot ulcers and neurogenic arthropathy.[paperity.org]
  • Sufferers experience: Fever Chills Sweating Headache Argyll Robertson Pupil Prevention There are no specific prevention guidelines for ARP as yet.[patienthelp.org]

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