Results of laboratory testing including mast cell mediator levels, and clinical symptoms on presentation and during follow-up were analyzed. [ncbi.nlm.nih.gov]

Infectious workup was negative and shave biopsy revealed a dense, diffuse dermal infiltrate of mast cells, consistent with diffuse cutaneous bullous mastocytosis-a rare variant of cutaneous mastocytosis. [ncbi.nlm.nih.gov]

Mast cell activation disease: a concise practical guide for diagnostic workup and therapeutic options. J Hematol Oncol, 4(10), 10.1186/1756-8722-4-10 [ii] Hartmann K, et al. (2016). [mastattack.org]

A bone scan, GI workup, and identification of the D816V c-kit mutation can also be helpful in cases where the diagnosis requires confirmation. [merckmanuals.com]

The pattern of aeroallergen and food sensitization and asthma in atopic patients with mastocytosis did not differ from that found in patients without mastocytosis but a comprehensive allergic workup (including skin prick testing, total and specific IgE [worldallergy.org]

Treatment was started with oral dimethindine maleate. At the age of 18 months, oral sodium cromoglicate (SCG) was introduced. At the age of 23 months, additional treatment was started with a cutaneous emulsion containing 4% SCG. [ncbi.nlm.nih.gov]

Pharmacological treatment: systemic and topical 4 agents to control pruritus and achieve a good quality of life. [analesdepediatria.org]

Although our results suggest generally favourable prognosis, the review of the literature indicate that SM may occur. Therefore, more guarded prognosis should be given in DCM patients. [ncbi.nlm.nih.gov]

Articles in this issue include Human Mast Cell Signal Transduction; Mast cell tryptase role in homeostasis and coagulation; Mastocytosis: Current Classification and Diagnostic criteria; Epidemiology, risk factors and prognosis of mastocytosis; Mast cell [books.google.com]

Although childhood mastocytosis has a good prognosis but sometimes it may be progressive and can be fatal. [ijpd.in]

Etiology in many patients involves an activating mutation (D816V) in the gene coding for the stem cell factor receptor c-kit, which is present on mast cells. [merckmanuals.com]

Etiology The etiology of mastocytosis remains unknown. Children who develop this disease usually have a self-limited disorder, whih often resolves before adulthood. [sdominko.tripod.com]

Etiology Mastocytosis probably is a hyperplastic response to an abnormal stimulus. [emedicine.medscape.com]

Articles in this issue include Human Mast Cell Signal Transduction; Mast cell tryptase role in homeostasis and coagulation; Mastocytosis: Current Classification and Diagnostic criteria; Epidemiology, risk factors and prognosis of mastocytosis; Mast cell [books.google.com]

Mastocytosis (cutaneous and systemic): Epidemiology, pathogenesis, and clinical manifestations. UpToDate. December 5, 2016; . Habashy J and Robles DT. Mastocytosis. Medscape Reference. May 15, 2017; . Fett NM, Teng J, and Longley BJ. [rarediseases.info.nih.gov]

A mutation of the oncogene C-KIT D816V is found in many (but not all) cases. [ 9 ] Epidemiology [ 10 ] This is a rare and heterogeneous group of disorders, of which urticaria pigmentosa is the most common manifestation. [patient.info]

Epidemiology cutaneous mastocytosis (CM): accounts for 80% of cases of mastocytosis. It most commonly seen in children, 80% of whom are less than 6 months old. [e-immunohistochemistry.info]

Epidemiology: Mastocytosis is seen in all ethnic backgrounds. Estimated incidence is approximately 1:20,000 (4). It occurs in males and females in approximately equal ratios. [worldallergy.org]

Pathophysiology Mastocytosis is now classified with the myeloproliferative neoplasms. [5] Increased local concentrations of soluble mast cell growth factor in lesions of cutaneous mastocytosis are believed to stimulate mast cell proliferation, melanocyte [emedicine.medscape.com]

In addition to the age of onset, adult and pediatric forms of mastocytosis differ in their clinical course and pathophysiology. [sdominko.tripod.com]

Pathophysiology Mast cells originate from bone marrow progenitor cells and are distributed throughout the connective tissues. They are concentrated in the skin around the peripheral nerves and adjacent to blood and lymphatic vessels. [aafp.org]

A comprehensive diagnostic approach, advanced therapeutic strategies, regular follow-ups, and instruction of patients and relatives on prevention and prophylaxis are highly indicated. [ncbi.nlm.nih.gov]

Mast cell stabilizers help prevent mast cells from releasing their chemical contents. Cromoglicic acid is the only medicine specifically approved by the FDA for the treatment of mastocytosis. [en.wikipedia.org]

Your skin Holds body fluids in, preventing dehydration Keeps harmful microbes out, preventing infections Helps you feel things like heat, cold, and pain Keeps your body temperature even Makes vitamin D when the sun shines on it Anything that irritates [icdlist.com]

Typical treatments include taking antihistamines to prevent the effect of mast cell histamine. [dailymail.co.uk]

[…] comprising lymphocytes and plenty of mast cells Click here to view The child was treated with an oral anti-histaminics (both H1 and H2 blocker) and a short-course (6 weeks) of an oral steroid (prednisolone) along with topical antibiotics (mupirocin) to prevent [ijpd.in]