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Diffuse Intrinsic Pontine Glioma
DIPG

Images

WIKIDATA, CC BY 4.0
WIKIDATA, CC BY 4.0
WIKIDATA, CC BY 4.0
WIKIDATA, CC BY 3.0
WIKIDATA, CC BY 3.0
WIKIDATA, CC BY 3.0
WIKIDATA, CC BY 3.0

Presentation

The authors present a case of diffuse intrinsic pontine glioma presenting in a newborn with stridor and respiratory distress that progressed to respiratory failure. [ncbi.nlm.nih.gov]

Musculoskeletal

  • Muscle Weakness

    Some symptoms are muscle weakness on one side of the body, swallowing problems, speech problems, crossed eyes, drowsiness, hearing loss, and personality changes. The brainstem has cranial nerves that control many of these functions. [web.archive.org]

  • Leg Weakness

    Weakness of facial muscles or facial asymmetry (one side of the face appearing different from the other). Arm and leg weakness. Unstable balance and co-ordination. Difficulties walking and speaking. [thebraintumourcharity.org]

Neurologic

  • Excitement

    By his own admission, Armstrong was excited by the X-15 – it was real and even the Dyna-Soar was a realistic possibility – but President John Kennedy’s lunar goal “was just so overpoweringly exciting that I decided to give us these other opportunities [americaspace.com]

Treatment

’s largest pediatric glioma treatment programs. [danafarberbostonchildrens.org]

Nanotechnology may offer therapeutic options for the treatment of DIPGs. Multiple nanoparticle formulations are currently being investigated for the treatment of DIPGs. [ncbi.nlm.nih.gov]

From diagnosis to treatment, our experts provide the care and support you need, when you need it. [mskcc.org]

Treatment of diffuse pontine gliomas. Follow @ReflectsOfGrace [web.archive.org]

Prognosis

KEYWORDS: brainstem neoplasms; glioma; magnetic resonance imaging; pons; prognosis [ncbi.nlm.nih.gov]

Epidemiology

This article summarizes the epidemiology, clinical presentation, diagnosis, prognosis, molecular genetics, current treatment, and future therapeutic directions for diffuse intrinsic pontine glioma. [ncbi.nlm.nih.gov]

Fisher, Epidemiology of Pediatric Central Nervous System Tumors, Brain Tumors in Children, 10.1007/978-3-319-43205-2_1, (1-15), (2018). [dx.doi.org]

Pathophysiology

Stanford University, Stanford, California, USA. [4] Department of Pathology, Stanford University, Stanford, California, USA. [5] Present addresses: Key Laboratory of Cell Differentiation and Apoptosis of National Ministry of Education, Department of Pathophysiology [ncbi.nlm.nih.gov]

Prevention

Gliomas are highly vascularized tumors, suggesting that the prevention of vessel formation by anti-angiogenic treatment might be effective. [ncbi.nlm.nih.gov]

However, with diseases such as brain tumors, the BBB can also prevent diagnostic and therapeutic agents from reaching their target. [en.wikipedia.org]

Communication between the surgical resection cavity and the ventricular system should be avoided to prevent the wafers from migrating into the ventricular system and causing obstructivehydrocephalus. [web.archive.org]

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