Edit concept Question Editor Create issue ticket

Dilated Cardiomyopathy 1NN

CMD1NN


Presentation

  • A heritable pattern is present in 20 to 30% of cases. Most familial CMD pedigrees show an autosomal dominant pattern of inheritance, usually presenting in the second or third decade of life (summary by Levitas et al., 2010, pubmed:20551992 ).[flybase.org]
  • This book presents an analysis and review by many experts of the present knowledge about heart muscle diseases and employs the approach to classi fication and terminology now generally, though not universally, agreed.[books.google.com]
  • Of the 21 patients whose heart size returned to normal, 13 (62%) are presently living, 9 (43%) with normal heart size. Of the other 27 patients only 10 (37%) are known to be presently alive, none with normal heart size.[annals.org]
Goiter
  • Of the 53 patients with morphological abnormalities 23 patients (all male) showed diffuse goiter as opposed to 29 nodular enlarged organs (24 male, 5 female). No clinically significant hypothyroidism or thyrotoxicosis was seen.[karger.com]

Workup

  • […] the typical medical examiner's/coroner's office and the current lack of partici- pation among major insurance companies and third-party payers for postmortem genetic testing, the daunting task of a comprehensive cardiac channelopathy/cardiomyopathy workup[insurancenewsnet.com]
  • All patients underwent preoperative right and left catheterization, as a part of their surgical workup. New York Heart Association (NYHA) functional class was assessed according to clinical presentation.[academic.oup.com]

Treatment

  • More Symptoms of Cardiomyopathy, dilated, type 1NN » • • • Back to: « Cardiomyopathy Dilated Diagnosis See also related information on diagnosis: Diagnosis of Cardiomyopathy Treatments See also the following treatment articles: Treatments for Cardiomyopathy[familydiagnosis.com]
  • Peripheral blood-derived CD34 stem cells for treatment of dilated cardiomyopathy Umbilical cord-derived mesenchymal stem cells for treatment of dilated cardiomyopathy Embryonic/Adult Cultured Cells Related to Dilated Cardiomyopathy: Bone marrow-derived[malacards.org]
  • . • Explain the process of valvular dysfunction and state treatments for aortic and mitral valve disease.[emedevents.com]
  • Symptomatic HCM treatment with beta-blockers and non-DHP calcium channel blockers is the mainstay of therapy. Appropriate treatment monitoring and medication education should be part of a global treatment approach.[uspharmacist.com]
  • Copyright 1997 by the Massachusetts Medical Society Introduction Heterogeneity of Clinical and Genetic Features Treatment of the Symptoms of Heart Failure Medical Therapy Pharmacological Options Strategies for Drug Therapy Treatment of Asymptomatic Patients[gilead.org.il]

Prognosis

  • Response to bed rest therapy and long-term prognosis apparently are affected by duration and severity of the heart disease at the time bed rest is instituted.[annals.org]
  • Prognosis The prognosis is often described as poor, with increased morbidity and mortality due to progressive heart failure, systemic embolization, and malignant ventricular arrhythmias.[tidsskriftet.no]
  • Levander-Lindgren M (1965) Studies in myocarditis IV late prognosis. Cardiologia 47: 209 PubMed CrossRef Google Scholar 18. Lorell BJ, Alderman EL, Mason JW (1978) Cardiac sarcoidosis.[link.springer.com]
  • (Ref. 19 - 21, 34 - 37 ) The prognosis for patients with different myosin mutations varies considerably.[gilead.org.il]
  • Clinic Familial Heart Rhythm Center Genetic Testing for Long QT Syndrome QTsyndrome.ch - History Of a Heart Disease Long QT syndrome HEART & BLOOD VESSEL DISORDERS - Long QT Syndrome Long QT Syndrome Other diagnostic methods FS55 All sections UpToDate Prognosis[drdiag.hu]

Etiology

  • Upon conclusion of this program, participants should be able to: Describe the etiology and pathophysiology of restrictive and other non-dilated cardiomyopathies and use this information to effectively diagnose and manage patients Recognize and diagnose[cveducation.mayo.edu]
  • Noninvasive diagnosis of coronary artery disease in patients with heart failure and systolic dysfunction of uncertain etiology, using late gadolinium-enhanced cardiovascular magnetic resonance. J Am Coll Cardiol. 2005;45(5): 743-8.[revfinlay.sld.cu]
  • The etiology was tracked down largely by Morin & Daniel in Quebec leading to the condition becoming known as Quebec beer-drinkers cardiomyopathy. Removal of the cobalt additive ended the epidemic in all locations.[aim-digest.com]
  • This then allows for re-entrant circuits and sets up the ventricle for another PVC after the next sinus beat, the constant interval between the sinus beat and PVC suggests a reentrant etiology rather than spontaneous automaticity of the ventricle.[wikivisually.com]
  • […] manner of many sudden deaths in the young are explained after a comprehensive medicolegal investigation that includes a conventional autopsy exami- nation, up to 50% of these cases of sudden death in the young remain unexplained, with no definite cardiac etiology[insurancenewsnet.com]

Epidemiology

  • : Australian male Genetics Mutation: Lys92Arg CALR3 protein Ca -binding chaperone Localized mainly in endoplasmic/sarcoplasmic reticulum Colocalizes with: SPTLC2 CMH 20 Nexilin (NEXN) ; Chromosome 1p31.1; Dominant Epidemiology: Chinese families Genetics[neuromuscular.wustl.edu]
  • In the field of epidemiology and studies with patient cohorts he is involved in characterization of cardiovascular risk factors and cardiovascular diseases by means of molecular genetics and deep molecular phenotyping.[heartdiseases.conferenceseries.com]
  • Starting in the mid 1970s, dozens of cross-sectional and prospective epidemiologic studies have solidly established an empiric alcohol-HTN link.[aim-digest.com]
  • Relevant External Links for RYR2 Genetic Association Database (GAD) RYR2 Human Genome Epidemiology (HuGE) Navigator RYR2 Atlas of Genetics and Cytogenetics in Oncology and Haematology: RYR2 No data available for Genatlas for RYR2 Gene Identification of[genecards.org]
  • Clinical and epidemiological aspects of Chagas disease. Lancet Infec Dis. 2001; 1 (2):92–100. [ PubMed ] [ Google Scholar ] 4. Lopes ER, Chapadeiro E. Morte súbita em área endêmica da doença de Chagas.[ncbi.nlm.nih.gov]
Sex distribution
Age distribution

Pathophysiology

  • Thereby novel methods of immunoprofiling, molecular biology, nanotechnology, and OMICs technologies are applied for studies of the pathophysiology of inflammatory cardiomyopathy, dilated cardiomyopathy, and heart failure development.[heartdiseases.conferenceseries.com]
  • Upon conclusion of this program, participants should be able to: Describe the etiology and pathophysiology of restrictive and other non-dilated cardiomyopathies and use this information to effectively diagnose and manage patients Recognize and diagnose[cveducation.mayo.edu]
  • Fulminant beriberi heart disease with lactic acidosis: presentation of a case with evaluation of left ventricular function and review of pathophysiologic mechanisms.[ncbi.nlm.nih.gov]
  • Pathophysiology of chest pain in patients with cardiomyopathies and normal coronary arteries. Circulation 1982;65:778-89. Cannon RO III, Rosing DR, Maron BJ, et al.[gilead.org.il]

Prevention

  • Used to : Generic Coumadin is used for treating or preventing blood clots that may occur in the veins and lungs.[grafixinn.de]
  • Restrictive Cardiomyopathy Disease Preventive cardiomyopathy is the least prevalent form. It happens when the ventricles harden and cannot relax sufficiently to fill with blood.[drugs-inn.com]
  • […] for primary prevention and should be performed every 1 to 2 years.[uspharmacist.com]
  • Other interventions include arrhythmia management using device therapy and sudden death prevention. Patients who are refractory to medical therapy might benefit from mechanical circulatory support and heart transplantation.[centogene.com]
  • However, stopping drinking at this point can prevent future damage. Some people who drink heavily may develop cirrhosis before developing alcoholic hepatitis.[sunrisehouse.com]

Ask Question

5000 Characters left Format the text using: # Heading, **bold**, _italic_. HTML code is not allowed.
By publishing this question you agree to the TOS and Privacy policy.
• Use a precise title for your question.
• Ask a specific question and provide age, sex, symptoms, type and duration of treatment.
• Respect your own and other people's privacy, never post full names or contact information.
• Inappropriate questions will be deleted.
• In urgent cases contact a physician, visit a hospital or call an emergency service!