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Diphyllobothrium Latum Infection


Presentation

  • This report aims to present the case of a 20-year-old patient with confirmed Diphyllobothrium latum infection.[ncbi.nlm.nih.gov]
  • Abstract Diphyllobothrium latum infections in 4 young Korean men detected from 2008 to 2012 are presented.[ncbi.nlm.nih.gov]
  • Published on Nov 22, 2015 PRESENTATION OUTLINE DIPHYLLOBOTHRIUM LATUM INFECTION SYMPTOMS SYMPTOMS pain above the stomach or in the abdomen (tummy) nausea or vomiting Diarrhoea weight loss loss of appetite SYMPTOMS dizziness insomnia fits Malnutrition[haikudeck.com]
  • He denied any blood in his stool, but did present with an approximately 3-foot flatworm which he passed in his stool the evening before presentation.[healio.com]
  • Consequently, these diseases have become the focus of recent research by parasitologists and pathologists whose work is presented in this book.[books.google.de]
Anemia
  • In Diphyllobothrium latum infection, true: A Definitive host is Cyclops B Infective agent is metacercaria C Produces macrocytic anemia due to B12 deficiency D All are true E None are true Ans. C Produces macrocytic anemia due to B12 deficiency a.[gradestack.com]
  • […] decreased) (9) mechanical bowel obstruction (10) vomiting or defecating several proglottids or a whole worm Laboratory findings (1) mild eosinophilia (2) macrocytic anemia ("tapeworm anemia") secondary to vitamin B12 deficiency (3) decreased serum vitamin[meducator3.net]
  • Blood examination may reveal a slight leukocytosis with eosinophilia and occasionally a megaloblastic anemia associated with B12 deficiency.[antiinfectivedrugs.com]
  • Research of Diphyllobothrium Latum Infection has been linked to Diphyllobothriasis, Infective Disorder, Anemia, Intestinal Diseases, Parasitic, Abdominal Pain.[novusbio.com]
  • One of them experienced abdominal pain and 6 experienced natural discharge of a chain of worm segments, but none revealed any sign of anemia. Total 12 worms (1-3/patient) were collected after praziquantel treatment.[parasitol.kr]
Weight Loss
  • Published on Nov 22, 2015 PRESENTATION OUTLINE DIPHYLLOBOTHRIUM LATUM INFECTION SYMPTOMS SYMPTOMS pain above the stomach or in the abdomen (tummy) nausea or vomiting Diarrhoea weight loss loss of appetite SYMPTOMS dizziness insomnia fits Malnutrition[haikudeck.com]
  • Review of systems was negative for fevers, night sweats, or involuntary weight loss. Physical exam was notable for an obese abdomen, but was otherwise unremarkable.[healio.com]
  • Infection is usually asymptomatic, but mild GI symptoms (eg, abdominal discomfort, diarrhea, weight loss) may be noted. Fish tapeworms take up dietary vitamin B 12, occasionally resulting in vitamin B12 deficiency and megaloblastic anemia.[msdmanuals.com]
  • Manifestations may include abdominal discomfort, diarrhea, vomiting, and weight loss. Vitamin B12 deficiency with pernicious anemia may occur. Massive infections may result in intestinal obstruction.[cdc.gov]
  • However symptoms can include abdominal discomfort, diarrhea, vomiting, and weight loss. Vitamin B12 deficiency leading to pernicious anemia may occur.[cdc.gov]
Prisoner of War
  • Intestinal parasite survey of Korean prisoner-of-war camp. U S Armed Forces Med J 1956;7(5):708–714. 2. Cho SY, et al. Seoul J Med 1971;12(3):157–163. 4. Chyu I, et al.. J Catholic Med Coll 1965;9:159–172. 5. Eguchi S..[parasitol.kr]
Camping
  • Intestinal parasite survey of Korean prisoner-of-war camp. U S Armed Forces Med J 1956;7(5):708–714. 2. Cho SY, et al. Seoul J Med 1971;12(3):157–163. 4. Chyu I, et al.. J Catholic Med Coll 1965;9:159–172. 5. Eguchi S..[parasitol.kr]
Abdominal Pain
  • Keywords: Diphyllobothrium latum Abdominal pain Diarrhea[kjp.or.kr]
  • The patientso main complaints were gastrointestinal troubles, such as mild abdominal pain, indigestion, and diarrhea, and discharge of tapeworm segments in the feces.[ncbi.nlm.nih.gov]
  • Research of Diphyllobothrium Latum Infection has been linked to Diphyllobothriasis, Infective Disorder, Anemia, Intestinal Diseases, Parasitic, Abdominal Pain.[novusbio.com]
  • If patients present with abdominal pain and diarrhea, the differential diagnosis includes a variety of infectious and noninfectious causes.[antiinfectivedrugs.com]
  • One of them experienced abdominal pain and 6 experienced natural discharge of a chain of worm segments, but none revealed any sign of anemia. Total 12 worms (1-3/patient) were collected after praziquantel treatment.[parasitol.kr]
Abdominal Cramps
  • Yoo Case 1 A 34-year-old Caucasian man with no significant past medical history presented in outpatient clinic with 7 days of diarrhea and 1 day of vomiting, abdominal cramping, and chills.[healio.com]
  • The symptoms are abdominal distention, flatulence, intermittent abdominal cramping, and diarrhea. abdominal distention 腹部膨満 abdominal 腹の, 腹部[腹腔(ふくこう)]の distention 広がる[広げる]こと, 膨張[拡張]作用 flatulence 腹にガスを生じさせる;〈病気などが〉鼓腸性の;〈人が〉ガスで腹の張った. intermittent abdominal[daxiongmao.exblog.jp]
Abdominal Distension
  • The main clinical complaints were intermittent gastrointestinal troubles such as indigestion, abdominal distension, and spontaneous discharge of tapeworm's segments in their feces.[ncbi.nlm.nih.gov]
Chronic Diarrhea
  • Chronic diarrhea may lead to malnutrition. Megaloblastic anemia secondary to B12 deficiency results when the parasite disrupts the B12-intrinsic factor complex, resulting in B12 becoming unavailable for absorption by the host.[antiinfectivedrugs.com]
Intestinal Disease
  • Research of Diphyllobothrium Latum Infection has been linked to Diphyllobothriasis, Infective Disorder, Anemia, Intestinal Diseases, Parasitic, Abdominal Pain.[novusbio.com]
Insomnia
  • Published on Nov 22, 2015 PRESENTATION OUTLINE DIPHYLLOBOTHRIUM LATUM INFECTION SYMPTOMS SYMPTOMS pain above the stomach or in the abdomen (tummy) nausea or vomiting Diarrhoea weight loss loss of appetite SYMPTOMS dizziness insomnia fits Malnutrition[haikudeck.com]
Peripheral Neuropathy
  • B12 deficiency may lead to neurologic sequelae including peripheral neuropathy, dementia, and possible severe combined degeneration of the posterior columns.[antiinfectivedrugs.com]

Workup

Macrocytic Anemia
  • In Diphyllobothrium latum infection, true: A Definitive host is Cyclops B Infective agent is metacercaria C Produces macrocytic anemia due to B12 deficiency D All are true E None are true Ans. C Produces macrocytic anemia due to B12 deficiency a.[gradestack.com]
  • anemia ("tapeworm anemia") secondary to vitamin B12 deficiency (3) decreased serum vitamin B12 Often the infection is found incidentally when the patient is being worked up for another problem.[meducator3.net]
Macrocytic Anemia
  • In Diphyllobothrium latum infection, true: A Definitive host is Cyclops B Infective agent is metacercaria C Produces macrocytic anemia due to B12 deficiency D All are true E None are true Ans. C Produces macrocytic anemia due to B12 deficiency a.[gradestack.com]
  • anemia ("tapeworm anemia") secondary to vitamin B12 deficiency (3) decreased serum vitamin B12 Often the infection is found incidentally when the patient is being worked up for another problem.[meducator3.net]
Macrocytosis
  • Laboratory evaluation was remarkable for a hemoglobin of 14.7, with macrocytosis (MCV 100), and no eosinophilia. Vitamin B12 level was not checked in the emergency department.[healio.com]

Treatment

  • Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions.[drugs.com]
  • An alternative treatment is Niclosamide, 2 g PO once for adults or 50 mg/kg PO once.[11] One should note that Praziquantel is not FDA approved for this indication and Niclosamide is not available for human use in the United States[haikudeck.com]
  • Abstract Seven cases of Diphyllobothrium latum infection were proved by collection of worms after praziquantel treatment between October, 1986 and July, 1987.[parasitol.kr]
  • Treatment of Diphyllobothrium is simple with a single dose of praziquantel 25mg/kg, with a repeat stool check 1 month following treatment to document cure.[healio.com]
  • Treatment Therapy for infection with D latum consists of either praziquantel or niclosamide (Box 2). Follow-up examinations of stool should be performed 1 and 3 months after treatment.[antiinfectivedrugs.com]

Prognosis

  • Prognosis Since the disease is not commonly associated with severe symptoms, the prognosis of infected individuals is excellent.[antiinfectivedrugs.com]
  • Human T-cell Leukemia Virus Type I Tax genotype analysis in Okinawa, the southernmost and remotest islands of Japan: Different distributions compared with mainland Japan, and the potential value for the prognosis of aggressive adult T-cell leukemia/lymphoma[kawasaki-m.ac.jp]

Etiology

  • Noninfectious etiologies to consider include osmotic (eg, lactose intolerance) and secretory (eg, villous adenoma) etiologies, malabsorption syndromes (eg, celiac sprue), and motility disorders (eg, irritable bowel syndrome).[antiinfectivedrugs.com]
  • (Etiology) Humans are infected by Diphyllobothriasis, when they eat raw or undercooked fish that contains fish tapeworm cysts (especially belonging to the tapeworm Diphyllobothrium latum) When an individual consumes the infected fish, the tapeworm larva[dovemed.com]

Epidemiology

  • In addition, background information on epidemiology, pathogenesis and pathophysiology encourages a fuller understanding of conditions, and over 250 full colour images help with diagnosis when treating patients.[books.google.de]
  • We briefly reviewed the 43 cases in terms of epidemiological, clinical, and parasitological aspects.[doi.org]
  • Discussion Epidemiology The first documented case of Diphyllobothrium latum in the United States was in 1906, in Minnesota.[healio.com]
  • […] normally infect piscivorous mammals and possibly birds Although Diphyllobothrium latum is the most common species to infect humans, differentiation cannot be made based on morphology - molecular methods are required ( Emerg Infect Dis 2014;20:1955 ) Epidemiology[pathologyoutlines.com]
  • Methods Statistics Trigonometry Medical & Nursing Anatomy Anesthesiology Audiology Bacteriology Biochemistry Bioethics Biomedical Science Cardiology Cardiovascular Childbirth Chiropractic Dentistry Dermatology Diagnostic Imaging Drugs Endocrinology Epidemiology[brainscape.com]
Sex distribution
Age distribution

Pathophysiology

  • In addition, background information on epidemiology, pathogenesis and pathophysiology encourages a fuller understanding of conditions, and over 250 full colour images help with diagnosis when treating patients.[books.google.de]
  • 2014;20:1955 ) Epidemiology Occurs in Northern Hemisphere (Europe, North America, Asia) and South America (Uruguay and Chile) Humans acquire larvae by ingesting raw or incompletely cooked fish that have spent at least part of their life in fresh water Pathophysiology[pathologyoutlines.com]

Prevention

  • This up-to-date and essential reference tool, supports all medical professionals in the treatment and prevention of infectious diseases.[books.google.de]
  • Prevention & Control Prevention of infection from D latum is achieved through adequate cooking of all freshwater fish or freezing of fish for 24-48 h at -18 C (Box 3). Isolation of infected persons is not required.[antiinfectivedrugs.com]
  • There are also preventative methods such as proper preparation of fish. [1] Diphyllobothrium latum, An Example of a "Stage 3" Parasite: In The Art of Being a Parasite, Claude Combs proposes that there are three stages of parasitism.[bio390parasitology.blogspot.com]
  • Until 1982, infection with Diphyllobothrium was a reportable disease in the United States, and the Centers for Disease Control and Prevention (CDC) estimated between 125 to 200 cases between 1977 and 1981.[healio.com]
  • The following preventive measures can be adopted to reduce the risk of Diphyllobothriasis: Eating raw or undercooked (especially freshwater) fish must be avoided. Cooking fish to temperatures over 145 deg. F (63 deg.[dovemed.com]

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