Presentation
The head is lacking, although many of the immature segments immediately following the head are present. The specimen is in several pieces, and the combined length of them [jamanetwork.com]
This report aims to present the case of a 20-year-old patient with confirmed Diphyllobothrium latum infection. [ncbi.nlm.nih.gov]
This paper presents an autochthonous case of Diphyllobothrium latum infection in Brasília, Federal District, Brazil. [scielo.br]
He denied any blood in his stool, but did present with an approximately 3-foot flatworm which he passed in his stool the evening before presentation. [healio.com]
Entire Body System
- Anemia
In Diphyllobothrium latum infection, true: A Definitive host is Cyclops B Infective agent is metacercaria C Produces macrocytic anemia due to B12 deficiency D All are true E None are true Ans. C Produces macrocytic anemia due to B12 deficiency a. [gradestack.com]
[…] decreased) (9) mechanical bowel obstruction (10) vomiting or defecating several proglottids or a whole worm Laboratory findings (1) mild eosinophilia (2) macrocytic anemia ("tapeworm anemia") secondary to vitamin B12 deficiency (3) decreased serum vitamin [meducator3.net]
Differential diagnosis should be made primarily between tapeworm anemia and genuine pernicious anemia. [histopathology-india.net]
Blood examination may reveal a slight leukocytosis with eosinophilia and occasionally a megaloblastic anemia associated with B12 deficiency. [antiinfectivedrugs.com]
CBC is done to check for anemia. Praziquantel Sometimes niclosamide (outside of the US) Treatment of diphyllobothriasis is with a single oral dose of praziquantel 5 to 10 mg/kg. [msdmanuals.com]
- Asymptomatic
Diphyllobothrium latum infection is typically an asymptomatic condition f. D. latum infection is sometimes associated with megaloblastic anemia due to vitamin B 12 deficiency. [gradestack.com]
Differential Diagnosis The most usual manifestation of D latum infection is asymptomatic carriage, which is incidentally discovered. [antiinfectivedrugs.com]
Documentation: Most patients with a fish tapeworm (Diphyllobothrium latum) are asymptomatic. Some patients may have symptoms, especially if comorbid conditions such as malnutrition are present. [meducator3.net]
While most infections are asymptomatic, complications include intestinal obstruction and gall bladder disease caused by migration of proglottids. [cdc.gov]
- Weight Loss
Published on Nov 22, 2015 PRESENTATION OUTLINE DIPHYLLOBOTHRIUM LATUM INFECTION SYMPTOMS SYMPTOMS pain above the stomach or in the abdomen (tummy) nausea or vomiting Diarrhoea weight loss loss of appetite SYMPTOMS dizziness insomnia fits Malnutrition [haikudeck.com]
Synonym: broad tapeworm ; fish tapeworm See: illustration Symptoms Patients often report abdominal pain, weight loss, digestive disorders, progressive weakness, and symptoms of pernicious anemia because the worm absorbs ingested vitamin B 12 from the [medical-dictionary.thefreedictionary.com]
Manifestations may include abdominal discomfort, diarrhea, vomiting, and weight loss. Vitamin B12 deficiency with pernicious anemia may occur. Massive infections may result in intestinal obstruction. [cdc.gov]
Infection is usually asymptomatic, but mild GI symptoms (eg, abdominal discomfort, diarrhea, weight loss) may be noted. Fish tapeworms take up dietary vitamin B 12, occasionally resulting in vitamin B12 deficiency and megaloblastic anemia. [msdmanuals.com]
- Fatigue
Clinical findings: (1) vague abdominal discomfort (2) pallor and fatigue (due to anemia) (3) diarrhea (4) headache (5) malaise (6) dizziness (7) neuropsychiatric complications of vitamin B12 deficiency (rare) (8) change in appetite (may be increased or [meducator3.net]
Some saltwater fishes may also harbor this organism Diphyllobothriasis may cause abdominal pain, appetite loss, diarrhea or constipation, vomiting, nausea, and fatigue. [dovemed.com]
Other less common symptoms that are associated with this disease include fatigue, diarrhea, dizziness, numbness of extremities, and sensation of hunger. [omicsonline.org]
Studies have shown that in patients infected with D. latum, twenty-five percent will manifest symptoms of abdominal pain, diarrhea, fatigue, headaches, or pernicious anemia.[9] A Korean study looking at D. latum infections identified a total of 49 cases [ncbi.nlm.nih.gov]
Other symptoms included anemia, fatigue, anorexia, fever, and myalgia in a few cases. In a total of 17 cases, there were natural discharge of proglottids in the feces, and in 4 cases no symptoms were complained (Table 1). [parasitol.kr]
- Pallor
Clinical findings: (1) vague abdominal discomfort (2) pallor and fatigue (due to anemia) (3) diarrhea (4) headache (5) malaise (6) dizziness (7) neuropsychiatric complications of vitamin B12 deficiency (rare) (8) change in appetite (may be increased or [meducator3.net]
B12 deficiency, pancytopenia, eosinophilia, and pernicious anemia.[4][12] Respiratory manifestations include dyspnea in the setting of severe vitamin B12 deficiency.[4] Dermatological manifestations include glossitis and allergic symptoms, as well as pallor [ncbi.nlm.nih.gov]
Gastrointestinal
- Abdominal Pain
He had suffered from recurrent lower abdominal pain and watery diarrhea for about 6 months. These episodes were characterized by vague abdominal pain that may be dull or crampy relatively. [e-cep.org]
Keywords: Diphyllobothrium latum | Abdominal pain | Diarrhea [kjp.or.kr]
The patientso main complaints were gastrointestinal troubles, such as mild abdominal pain, indigestion, and diarrhea, and discharge of tapeworm segments in the feces. [ncbi.nlm.nih.gov]
Research of Diphyllobothrium Latum Infection has been linked to Diphyllobothriasis, Infective Disorder, Anemia, Intestinal Diseases, Parasitic, Abdominal Pain. [novusbio.com]
- Overeating
Over a 10-day to 14-day period, the eggs transform into ciliated embryos with 6 hooks (called coracidia) that are released from the open opercula. [emedicine.medscape.com]
[…] the Counter Rx/OTC Prescription or Over the Counter Off Label This medication may not be approved by the FDA for the treatment of this condition. [drugs.com]
In addition, background information on epidemiology, pathogenesis and pathophysiology encourages a fuller understanding of conditions, and over 250 full colour images help with diagnosis when treating patients. [books.google.de]
“This was simply a more detailed evaluation of the Diphyllobothrium that has occurred here for over a millennium.” [wgntv.com]
"This was simply a more detailed evaluation of the Diphyllobothrium that has occurred here for over a millennium." [edition.cnn.com]
- Nausea
Published on Nov 22, 2015 PRESENTATION OUTLINE DIPHYLLOBOTHRIUM LATUM INFECTION SYMPTOMS SYMPTOMS pain above the stomach or in the abdomen (tummy) nausea or vomiting Diarrhoea weight loss loss of appetite SYMPTOMS dizziness insomnia fits Malnutrition [haikudeck.com]
Common gastrointestinal complaints associated with helminth infection include abdominal pain, nausea, and diarrhea. [amboss.com]
Some saltwater fishes may also harbor this organism Diphyllobothriasis may cause abdominal pain, appetite loss, diarrhea or constipation, vomiting, nausea, and fatigue. [dovemed.com]
However, some cases have been associated with megaloblastic anemia, gastrointestinal discomfort, anorexia, nausea, vomiting, asthenia, weight loss, eosinophilia and diarrhea. [scielo.br]
Some feel a little bit of abdominal discomfort, some have nausea or loose stools, and some even lose a little weight. [wgntv.com]
- Abdominal Cramps
The symptoms are abdominal distention, flatulence, intermittent abdominal cramping, and diarrhea. abdominal distention 腹部膨満 abdominal 腹の, 腹部[腹腔(ふくこう)]の distention 広がる[広げる]こと, 膨張[拡張]作用 flatulence 腹にガスを生じさせる;〈病気などが〉鼓腸性の;〈人が〉ガスで腹の張った. intermittent abdominal [daxiongmao.exblog.jp]
At her consultation with the physician, she reported that she had been suffering from gastrointestinal disorders such as abdominal cramps, flatulence, sporadic diarrhea, polyphagia and other unspecific symptoms like intense general itching and irritability [scielo.br]
Yoo Case 1 A 34-year-old Caucasian man with no significant past medical history presented in outpatient clinic with 7 days of diarrhea and 1 day of vomiting, abdominal cramping, and chills. [healio.com]
- Abdominal Distension
The main clinical complaints were intermittent gastrointestinal troubles such as indigestion, abdominal distension, and spontaneous discharge of tapeworm's segments in their feces. [ncbi.nlm.nih.gov]
Cardiovascular
- Heart Disease
Cestode larvae Diphyllobothrium dendriticum as a cause of a heart disease leading to mortality in hatcheryreared sea trout and brown trout. Diseases of Aquatic Organisms 25:15–22 Revenga, J. (1993). [revistaaquatic.com]
Skin
- Urticaria
Side effects of praziquantel include weakness, headache, dizziness, abdominal pain, fever, and possibly urticaria.[4][17] An alternative anthelminthic drug used for D. latum infections is a single dose of niclosamide, which is given either in a single [ncbi.nlm.nih.gov]
- Pruritus
Prevalence in the US: ∼ 40 million Primarily children 5–10 years of age Mode of transmission Initial infection: fecal-oral Reinfection: digital-oral after scratching anal region Clinical features Anal pruritus (especially at night) ♀ : vulvovaginitis, [amboss.com]
Neurologic
- Irritability
Noninfectious etiologies to consider include osmotic (eg, lactose intolerance) and secretory (eg, villous adenoma) etiologies, malabsorption syndromes (eg, celiac sprue), and motility disorders (eg, irritable bowel syndrome). [antiinfectivedrugs.com]
At her consultation with the physician, she reported that she had been suffering from gastrointestinal disorders such as abdominal cramps, flatulence, sporadic diarrhea, polyphagia and other unspecific symptoms like intense general itching and irritability [scielo.br]
- Paresthesia
[…] the most common symptom following by abdominal pain.[13] Diphyllobothriasis can affect different organ systems with varied manifestations and are listed below based on published case reports and series: Central nervous system manifestations include paresthesia [ncbi.nlm.nih.gov]
Workup
Dermatological manifestations include glossitis and allergic symptoms, as well as pallor.[4] Evaluation In the appropriate clinical picture with signs and symptoms consistent with diphyllobothriasis, the clinician should consider initial laboratory workup [ncbi.nlm.nih.gov]
Serum
- Macrocytic Anemia
In Diphyllobothrium latum infection, true: A Definitive host is Cyclops B Infective agent is metacercaria C Produces macrocytic anemia due to B12 deficiency D All are true E None are true Ans. C Produces macrocytic anemia due to B12 deficiency a. [gradestack.com]
[…] decreased) (9) mechanical bowel obstruction (10) vomiting or defecating several proglottids or a whole worm Laboratory findings (1) mild eosinophilia (2) macrocytic anemia ("tapeworm anemia") secondary to vitamin B12 deficiency (3) decreased serum vitamin [meducator3.net]
- Macrocytosis
Laboratory evaluation was remarkable for a hemoglobin of 14.7, with macrocytosis (MCV 100), and no eosinophilia. Vitamin B12 level was not checked in the emergency department. [healio.com]
Microbiology
- Taenia Saginata
Thirteen patients with tapeworm infection, seven with Diphyllobothrium latum and six with Taenia saginata, were treated by the introduction of a radio-opaque contrast medium, 'Gastrografin', into the duodenum through a duodenal tube. [thelancet.com]
The familiar pork and beef tapeworms are in a different genus, Taenia ( Taenia solium and Taenia saginata, respectively). Immature eggs of D. latum are passed in feces from the definitive host (i.e., the host harboring adults, or "final" host). [eol.org]
"Successful treatment of Diphyllobothrium latum and Taenia saginata infection by intraduodenal 'Gastrografin' injection". Lancet. 2 (8516): 1124–6. doi : 10.1016/S0140-6736(86)90532-5. PMID 2877274. ^ Ko, S.B. [en.wikipedia.org]
"Successful treatment of Diphyllobothrium latum and Taenia saginata infection by intraduodenal 'Gastrografin' injection". Lancet 2: 1124–6. [bionity.com]
Intestinal taeniasis Cysticercosis Pathogen Taenia saginata (beef tapeworm ) ( up to 25 m in length, usually ≤ 5 m ) Taenia solium ( pork tapeworm ) ( up to 7 m in length) Taenia solium ( pork tapeworm ) Mode of transmission Ingestion of larvae ( cysticerci [amboss.com]
- Taenia Solium
Intestinal taeniasis Cysticercosis Pathogen Taenia saginata (beef tapeworm ) ( up to 25 m in length, usually ≤ 5 m ) Taenia solium ( pork tapeworm ) ( up to 7 m in length) Taenia solium ( pork tapeworm ) Mode of transmission Ingestion of larvae ( cysticerci [amboss.com]
The familiar pork and beef tapeworms are in a different genus, Taenia ( Taenia solium and Taenia saginata, respectively). Immature eggs of D. latum are passed in feces from the definitive host (i.e., the host harboring adults, or "final" host). [eol.org]
Laboratory
- Leukocytosis
Blood examination may reveal a slight leukocytosis with eosinophilia and occasionally a megaloblastic anemia associated with B12 deficiency. [antiinfectivedrugs.com]
[…] myalgia, muscle swelling, weakness Periorbital edema Other symptoms include: fever, rash, splinter hemorrhages, retinal and conjunctival hemorrhages, chemosis Diagnosis Initial test: complete blood cell ( CBC ) count showing eosinophilia (and sometimes leukocytosis [amboss.com]
Treatment
Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. [drugs.com]
An alternative treatment is Niclosamide, 2 g PO once for adults or 50 mg/kg PO once.[11] One should note that Praziquantel is not FDA approved for this indication and Niclosamide is not available for human use in the United States [haikudeck.com]
Treatment [ edit ] Upon diagnosis, treatment is quite simple and effective. [en.wikipedia.org]
This treatment had no serious adverse effects in any of our patients. [thelancet.com]
Praziquantel Sometimes niclosamide (outside of the US) Treatment of diphyllobothriasis is with a single oral dose of praziquantel 5 to 10 mg/kg. [msdmanuals.com]
Prognosis
Prognosis Since the disease is not commonly associated with severe symptoms, the prognosis of infected individuals is excellent. [antiinfectivedrugs.com]
Prognosis The prognosis of D. latum infections will depend on the patient’s disease severity, comorbid conditions, as well as worm burden within the intestinal tract. [ncbi.nlm.nih.gov]
Human T-cell Leukemia Virus Type I Tax genotype analysis in Okinawa, the southernmost and remotest islands of Japan: Different distributions compared with mainland Japan, and the potential value for the prognosis of aggressive adult T-cell leukemia/lymphoma [kawasaki-m.ac.jp]
Etiology
Noninfectious etiologies to consider include osmotic (eg, lactose intolerance) and secretory (eg, villous adenoma) etiologies, malabsorption syndromes (eg, celiac sprue), and motility disorders (eg, irritable bowel syndrome). [antiinfectivedrugs.com]
(Etiology) Humans are infected by Diphyllobothriasis, when they eat raw or undercooked fish that contains fish tapeworm cysts (especially belonging to the tapeworm Diphyllobothrium latum) When an individual consumes the infected fish, the tapeworm larva [dovemed.com]
Etiology Diphyllobothriasis occurs from the ingestion of larval forms of the fish tapeworm, with the most common species being D. latum. Molecular identification analyses have revealed numerous genus and species with potential for human infectivity. [ncbi.nlm.nih.gov]
Epidemiology
The topics on epidemiology, diagnosis, and clinical aspects emphasize the knowledge gaps that limit a full understanding of these zoonoses, and target where greater research investments on these parasitic diseases should be focused. [books.google.de]
Diphyllobothrium latum From the journal The Japanese journal of antibiotics ISSN : 0368-2781 Other information Language : Japanese Type : Journal Article In AGRIS since : 2013 Volume : 36 Issue : 3 Start Page : 566 End Page : 572 (p. 86-92) All titles : " Epidemiology [agris.fao.org]
This activity reviews the epidemiology, evaluation, and management of this parasitic infection and highlights the role of the interprofessional team in caring for affected patients. Objectives: Describe the epidemiology of diphyllobothriasis. [ncbi.nlm.nih.gov]
Epidemiological studies such as these are necessary for tracking the distribution of different Diphyllobothrium species and monitoring epidemics worldwide. [web.stanford.edu]
Pathophysiology
In addition, background information on epidemiology, pathogenesis and pathophysiology encourages a fuller understanding of conditions, and over 250 full colour images help with diagnosis when treating patients. [books.google.de]
2014;20:1955 ) Epidemiology Occurs in Northern Hemisphere (Europe, North America, Asia) and South America (Uruguay and Chile) Humans acquire larvae by ingesting raw or incompletely cooked fish that have spent at least part of their life in fresh water Pathophysiology [pathologyoutlines.com]
Review the pathophysiology of diphyllobothriasis. Outline the ways that a patient with diphyllobothriasis might present. [ncbi.nlm.nih.gov]
Prevention
This up-to-date and essential reference tool, supports all medical professionals in the treatment and prevention of infectious diseases. [books.google.de]
According to WHO guidelines for mass prevention campaigns, the use of praziquantel during lactation is encouraged. [cdc.gov]
Prevention & Control Prevention of infection from D latum is achieved through adequate cooking of all freshwater fish or freezing of fish for 24-48 h at -18 °C (Box 3). Isolation of infected persons is not required. [antiinfectivedrugs.com]