Edit concept Question Editor Create issue ticket

Disaccharidase Deficiency

Disaccharide Malabsorption


Presentation

  • Histological abnormality was not always present with disaccharidase deficiency. There was no significant difference in intraepithelial lymphocyte counts between the two groups.[ncbi.nlm.nih.gov]
  • In all patients, moderate to severe mucosal changes were presented, associated with marked inflammation of lamina propria and damages to the brushborder.[ncbi.nlm.nih.gov]
  • Show Summary Details Preview Disaccharidases occur in the microvilli of the small intestine and are required for the complete assimilation of nearly all carbohydrate present in food and drinks, apart from free glucose and fructose.[oxfordindex.oup.com]
  • Disaccharidases occur in the microvilli of the small intestine and are required for the complete assimilation of nearly all carbohydrate present in food and drinks, apart from free glucose and fructose.[oxfordmedicine.com]
  • Confirm each diagnosis by consulting a section, organized by symptoms, that presents the full range of differential diagnoses and treatment options for each specific condition.[books.google.com]
Sucrose Intolerance
  • SNOMED Clinical Terms Synonyms: • Deficiency of isomaltase • Disacchariduria • Impaired glucose tolerance in nonobese • Lactosuria • Small intestine glucose intolerance • Sucrose intolerance • Sucrosuria Lactose Intolerance Also called: Dairy product[coding-pro.com]
  • intolerance Sucrosuria Applies To Intolerance or malabsorption (congenital) (of): glucose-galactose lactose sucrose-isomaltose ICD-9-CM Volume 2 Index entries containing back-references to 271.3 :[icd9data.com]
  • intolerance Sucrosuria References to Index of Diseases and Injuries The code 271.3 has the following ICD-9-CM references to the Index of Diseases and Injuries Absorption lactose defect 271.3 Alactasia (hereditary) 271.3 Deficiency, deficient disaccharidase[healthprovidersdata.com]
  • A free Sucrose Intolerance Hydrogen Breath Test is available through your healthcare provider. For more information or to order a test kit, call 1-800-705-1962 .[sucraid.net]
  • A genetic defect in one of these enzymes will cause a disaccharide intolerance, such as lactose intolerance or sucrose intolerance .[en.wikipedia.org]
Diarrhea
  • Abstract 7 infants, aged 5 weeks to 11 months, with clinically documented intolerance to cow's milk protein, chronic diarrhea, and failure to thrive, underwent small intestinal (peroal, suction) biopsy before and after withdrawal of milk proteins.[ncbi.nlm.nih.gov]
  • Clinical signs include abdominal cramping, bloating , flatulence and diarrhea following dietary intake of lactose , maltose or sucrose .[tititudorancea.com]
  • […] membrane of villous absorptive epithelial cells Congenital deficiency: Rare; malabsorption evident with milk feeding, which causes explosive, watery, frothy stools and abdominal distention Acquired deficiency: Common in North American blacks Causes osmotic diarrhea[pathologyoutlines.com]
  • You may also have Gas Diarrhea Swelling in your stomach Your doctor may do a blood, breath or stool test to find out if your problems are due to lactose intolerance. Lactose intolerance is not serious.[coding-pro.com]
Lactose Intolerance
  • The topic Disaccharidase Deficiency (Lactose Intolerance) you are seeking is a synonym, or alternative name, or is closely related to the medical condition Lactose Intolerance .[dovemed.com]
  • NIH: National Institute of Diabetes and Digestive and Kidney Diseases Lactose intolerance Lactose Intolerance - NIH (National Institute of Diabetes and Digestive and Kidney Diseases) Milk for Kids with Lactose Intolerance (Food and Nutrition Service)[coding-pro.com]
  • This review highlights the types, symptoms and management of lactose intolerance and also highlights differences from milk allergy which closely mimics the symptoms of lactose intolerance.[deepdyve.com]
  • intolerance Impaired glucose tolerance in nonobese Intestinal disaccharidase deficiency Lactase deficiency Lactase deficiency in diseases other than of the small intestine Lactose intolerance Lactose intolerance in children without lactase deficiency[icd9data.com]
Chronic Diarrhea
  • Abstract 7 infants, aged 5 weeks to 11 months, with clinically documented intolerance to cow's milk protein, chronic diarrhea, and failure to thrive, underwent small intestinal (peroal, suction) biopsy before and after withdrawal of milk proteins.[ncbi.nlm.nih.gov]
  • diarrhea, and failure to thrive, underwent small intestinal (peroral, suction) biopsy before and after withdrawal of milk proteins.[karger.com]
  • They often include chronic diarrhea, abnormal stools, weight loss, and gas. Your doctor may use lab, imaging, or other tests to make a diagnosis. Treatment of malabsorption syndromes depends on the cause.[icdlist.com]
  • Chronic diarrhea and alkalosis. To be published. Google Scholar 9. Cozzetto, F. J. Intestinal lactase deficiency in a patient with cystic fibrosis. Pediatrics 32 :228, 1963. PubMed Google Scholar 10. Gryboski, J. D., Thayer, W.[link.springer.com]
  • As more carbohydrates are left in the gut, they cause water and nutrients to be pulled from the body into the colon, resulting in chronic diarrhea.[pecanbread.com]
Abdominal Pain
  • A recent report indicated a high rate of disaccharidase deficiencies among children with recurrent abdominal pain. Here’s the abstract link: Disaccharidase Deficiencies in Children With Chronic Abdominal Pain (K El-Chammas, SE Williams, A Miranda.[gutsandgrowth.wordpress.com]
  • Disaccharide Deficiency Symptoms The most common symptoms associated with the Disaccharide deficiency include, Abdominal bloating and distention Flatulence Diarrhea Abdominal pain and discomfort Foul smelling stools and floating stools Malnutrition and[tandurust.com]
  • Bacterial fermentation of carbohydrates in the colon produces gases (hydrogen, carbon dioxide, and methane), resulting in excessive flatus, bloating and distention, and abdominal pain.[merckmanuals.com]
  • Also write down the timing of any symptoms the patient experiences such as bloating , gas, diarrhea, or abdominal pain. This detailed food record will help the RD plan a diet more effectively.[csidcares.org]
Abdominal Distension
  • Clinical manifestations include osmotic-fermentative diarrhea, abdominal distension and discomfort, flatulence, vomiting and diaper rash. 2 Severe symptoms may lead to failure to thrive, dehydration and malnutrition.[elsevier.es]

Workup

  • If Genetic Sucrase-Isomaltase Deficiency is suspected, the diagnostic workup could include an upper gastrointestinal endoscopy, in which several biopsies (tissue specimens) are obtained from the small intestine and sent for a specialized laboratory analysis[sucraid.net]
Acanthocytes
  • Thorny shaped erythrocytes (acanthocytes) are a feature of the disease.[books.google.com]

Treatment

  • Significant updates on bariatric surgery, Barrett's esophagus, endoscopic ultrasound, endosonography, treatment of liver disease, and much more keep you current on the latest advances.[books.google.com]
  • Further regular health checks are an integral part of the treatment procedure.[tandurust.com]
  • Make informed clinical choices for each patient , from diagnosis and treatment selection through post-treatment strategies and management of complications, with new evidence-based criteria throughout.[books.google.com]
  • Treatment . The most effective method of treatment disaccharidase deficiency is to exclude from dietary intake of those carbohydrates that there is intolerance. Most often this refers milk sugar (fresh milk).[medicalency.com]
  • Review the latest developments in the field and get up-to-date clinical information on hot topics like polyps, capsule endoscopy, and pancreatic treatments.[books.google.com]

Prognosis

  • […] avoid dairy products from their diets have a favorable outcome Please find comprehensive information on Lactose Intolerance regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis[dovemed.com]
  • […] treatment is a lifelong adherence to a sucrose- and starch-restricted diet. 5 Effective enzyme replacement with whole yeast cells has been reported. 6 Purified yeast enzyme, sacrosidase, is a highly effective therapy and allows a normal diet. 4 CSID's prognosis[elsevier.es]

Etiology

  • The etiology and pathogenesis . There are congenital and acquired disaccharidase deficiency. The first is related to a congenital defect in the mucous membrane, which violates the synthesis of enzymes.[medicalency.com]
  • .: Idiopathic lacta" deficiency in adolescents and adults: genetic or environmental etiology. Annual Review of Medicine. Vol. 22, 1971. 11—NewcomerA, .: Lactase deficiency: a oommon genetic trait of the American Indian.[200.12.169.32]
  • Etiology Enzyme deficiencies can be Congenital (eg, rare deficiencies of lactase or sucrase-isomaltase) Acquired (primary) Secondary Acquired lactase deficiency (primary adult hypolactasia) is the most common form of carbohydrate intolerance.[merckmanuals.com]

Epidemiology

  • Genetics and epidemiology of adult-type hypolactasia. Scand J Gastroenterol. 1994;29:S7–20. 18. Desai HG, Gupta UV, Pradhan AG, Thakkar KD. Incidence of lactase deficiency in India. Role of hereditary factors. Ind J Med Sci. 1970;24:729–36. 19.[springermedizin.de]
Sex distribution
Age distribution

Pathophysiology

  • The book discusses the intestinal factors in the regulation of insulin secretion; antidiuretic hormone synthesis, release, and action under normal and pathological circumstances; and the symptoms, pathophysiology, diagnosis, and clinical syndromes of[books.google.com]
  • Pathophysiology Disaccharides are normally split into monosaccharides by disaccharidases (eg, lactase, maltase, isomaltase, sucrase [invertase]) located in the brush border of small-bowel enterocytes.[merckmanuals.com]

Prevention

  • Individuals who avoid dairy products from their diets have a favorable outcome Please find comprehensive information on Lactose Intolerance regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention[dovemed.com]
  • Get optimal test results with guidance on error detection, correction, and prevention as well as cost-effective test selection.[books.google.com]
  • Is chronic lung disease in low birth weight infants preventable? A survey of eight centers. ‎ Página 84 - Tanner JM, Whitehouse RH, Marubini E, Resele LF. The adolescent growth spurt of boys and girls of the Harpenden growth study. ‎[books.google.es]
  • Furthermore saliva contains endothelial growth factor - this stimulates tight junctions between cells and prevents leaky gut.[drmyhill.co.uk]
  • In the large intestine, each type inhibits an overabundance of the others, and this prevents the waste products and toxins of a particular type of microbe from overwhelming the body.[pecanbread.com]

Ask Question

5000 Characters left Format the text using: # Heading, **bold**, _italic_. HTML code is not allowed.
By publishing this question you agree to the TOS and Privacy policy.
• Use a precise title for your question.
• Ask a specific question and provide age, sex, symptoms, type and duration of treatment.
• Respect your own and other people's privacy, never post full names or contact information.
• Inappropriate questions will be deleted.
• In urgent cases contact a physician, visit a hospital or call an emergency service!