Presentation
444 Total Medicare Hospitalizations - Oct 2015 to Sep 2018 (Present on Admission - All) Total National Projected Hospitalizations - Annualized (Present on Admission - Yes) Total Medicare Hospitalizations - Oct 2015 to Sep 2018 (Present on Admission - [dexur.com]
Age and Sex edits from the Medicare Code Editor alert you to codes that are used only with patients of a specific age or sex, helping to ensure accurate reporting Present on Admission symbol highlights the diseases that will always be coded as present [books.google.com]
Many disease forms presents with combinations of akinetic phenomenology. A differential diagnostic approach to the understanding of different lesions of the nervous system with similar presentations will be embraced. [carrickinstitute.com]
Scleromalacia perforans may present with minimal/no symptoms. Posterior scleritis may present with very severe symptoms but a quiet white eye. [patient.info]
The underlying sources presented here present data only for the disorders of anorexia and bulimia nervosa (as defined below). [ourworldindata.org]
Entire Body System
- Inflammation
Granulomatous Inflammations • Exogenous • Endogenous The etiology of most cases of granulomatous inflammation is not known. Connective tissue diseases are common in a third of cases. [asiteforeyes.com]
Inflammations of the lacrimal sac are much more common. [britannica.com]
Episcleritis is inflammation of the superficial, episcleral layer of the eye. It is relatively common, benign and self-limiting. Scleritis is inflammation involving the sclera. [patient.info]
Long-term inflammation. Also called uveitis, long-term inflammation of the eye can damage related tissues. According to British researchers behind a study published in Acta Ophthalmologica, uveitis is the most common cause of end-stage eye. [healthline.com]
In some cases, inflammation may be due to a clumping of a certain type of cell (granulomatous inflammation). [rarediseases.org]
- Swelling
[…] abscess or intracranial extension Primarily a clinical diagnosis Laboratory tests: leukocytosis; blood cultures are generally unnecessary CT scan: only eyelid swelling apparent Treatment Empiric IV antibiotic treatment includes vancomycin PLUS one of [amboss.com]
Sties originating in the lash follicles are usually infectious and start as a painful swelling of the lid. [britannica.com]
Symptoms can include sudden vision loss, as well as diplopia, eye pain, and/or swelling. Physical exam findings may include decreased vision, chemosis, afferent pupillary defect, proptosis, and elevated intraocular pressure. [merckmanuals.com]
You might experience one or more of the following in the affected eye(s): blurry, cloudy vision floaters (dark spots that float across your eyes) light sensitivity pain redness swelling tenderness around the eye visual loss With phthisis bulbi, your eye [healthline.com]
- Crying
[…] to be held or cuddled or might cuddle only when they want to Appear to be unaware when people talk to them, or repeat words or phrases in place of normal language (echolalia) Have trouble expressing their needs using typical words or motions Laugh, cry [autismsociety-nc.org]
Wait, now she is back; she's crying and depressed and requires you for emotional support. [psychotherapy.thementalhealth.clinic]
Gastrointestinal
- Vomiting
Bulimia nervosa is an eating disorder characterised by binge eating followed by purging, which can include vomiting, taking laxatives, fasting or exercising excessively. [wirralglobe.co.uk]
Vomiting, which can increase intraocular pressure (IOP) and contribute to extravasation of ocular contents, is suppressed using antiemetics as needed. [merckmanuals.com]
One or more of the following may also be present: self-induced vomiting; self-induced purging; excessive exercise; use of appetite suppressants and/or diuretics; (c) There is body-image distortion in the form of a specific psychopathology whereby a dread [ourworldindata.org]
Occasional associated systemic symptoms (fever, vomiting, headache). Scleromalacia perforans may present with minimal/no symptoms. Posterior scleritis may present with very severe symptoms but a quiet white eye. [patient.info]
- Nausea
Thus, IOP is monitored daily for several days and then regularly over subsequent weeks and months and if symptoms develop (eg, eye ache, decreased vision, nausea—similar to symptoms of acute angle-closure glaucoma). [merckmanuals.com]
Cardiovascular
- Hypertension
[…] unspecified 360.31 Primary hypotony of eye 360.32 Ocular fistula causing hypotony 360.33 Hypotony associated with other ocular disorders 360.34 Flat anterior chamber of eye 360.40 Degenerated globe or eye, unspecified 360.41 Blind hypotensive eye 360.42 Blind hypertensive [healthprovidersdata.com]
[…] endophthalmitis ( 360.11 ) Sympathetic uveitis ( 360.2 ) Degenerative disorders of globe ( 360.3 ) Hypotony of eye ( 360.4 ) Degenerated conditions of globe ( 360.40 ) Degenerated globe or eye unspecified ( 360.41 ) Blind hypotensive eye ( 360.42 ) Blind hypertensive [en.wikipedia.org]
[…] canthotomy followed by: Monitoring with possible inpatient hospitalization with elevation of the bed to 45° Reversal of any coagulopathy Prevention of further increasing intraocular pressure (preventing or minimizing pain, nausea, cough, straining, severe hypertension [merckmanuals.com]
- Thrombosis
Acute unilateral proptosis suggests infection or vascular disorder (eg, hemorrhage, fistula, cavernous sinus thrombosis). Chronic unilateral proptosis suggests tumor. Do CT or MRI and thyroid function testing when Graves disease is suspected. [merckmanuals.com]
In patients with orbital cellulitis, the development of headache, ophthalmoplegia, facial hypesthesia in regions innervated by V1 and V2, and/or seizures should raise suspicion for cavernous sinus thrombosis. [amboss.com]
Skin
- Ulcer
Prolonged exposure of larger-than-usual areas of the eyeball to air causes corneal drying and can lead to infection and ulceration. [merckmanuals.com]
These include: psoriasis rheumatoid arthritis Ankylosing spondylitis (arthritis of the spine) ulcerative colitis herpes AIDS multiple sclerosis Kawasaki disease (blood vessel inflammation) syphilis tuberculosis [healthline.com]
The most commonly associated systemic disorders are ulcerative colitis and Crohn's disease. Hyperuricaemia is seen in about 11%. [patient.info]
inflammation, and filament formation; thus, FK often becomes chronic, and is a common finding in severe DED. 21,22 Rarely, severe DED may lead to complications such as ocular surface keratinization; microbial keratitis; corneal neovascularization, ulceration [ajmc.com]
[…] defined in usa ( 369.6 ) Profound vision impairment one eye ( 369.7 ) Moderate or severe vision impairment one eye ( 369.8 ) Unqualified visual loss one eye ( 369.9 ) Unspecified visual loss Disorders of cornea [ edit ] ( 370 ) Keratitis ( 370.0 ) Corneal ulcer [en.wikipedia.org]
- Eruptions
A journalist described him as "chilly and inscrutable," while his former chief of staff recalled him as "vindictive, prone to sudden eruptions of white-hot rage over meaningless trivia." These traits, too, are uniformly markers of trauma. [theglobeandmail.com]
- Photosensitivity
Self induced photosensitive epilepsy. Indian journal of pediatrics, 71(7), 649-651. [massgeneral.org]
Eyes
- Diplopia
Some Causes of Proptosis Cause Suggestive Findings Diagnostic Approach Graves disease Eye symptoms: Eye pain, lacrimation, dry eyes, irritation, photophobia, ocular muscle weakness causing diplopia, vision loss caused by optic nerve compression Systemic [merckmanuals.com]
Reduced vision, diplopia, ophthalmoplegia, and proptosis are typical features of orbital cellulitis. They do not occur in preseptal cellulitis! [amboss.com]
Most individuals with DRS have strabismus in primary gaze but can use a compensatory head position to align the eyes, avoiding diplopia. [orpha.net]
It presents with a variety of clinical features including diplopia, anisometropia, and amblyopia. 378.71 Duane's syndrome[1] Disease Duane Retraction Syndrome, also known as Stilling-Turk-Duane Syndrome, was originally described by Alexander Duane in [eyewiki.aao.org]
- Strabismus
Duane Retraction Syndrome is a congenital strabismus syndrome occurring in isolated or syndromic forms. [eyewiki.aao.org]
Strabismus 2010;18:21-3. 63. Maya JF, de Liaño RG, Catalán MR, Rayward O. Botulinum toxin treatment in patients up to 3 years of age who have esotropic Duane retraction syndrome. Strabismus 2013;21:4-7. [e-tjo.org]
( 378.6 ) Mechanical strabismus ( 378.7 ) Other specified strabismus ( 378.72 ) Progressive external ophthalmoplegia ( 378.8 ) Other disorders of binocular eye movements ( 378.86 ) Internuclear ophthalmoplegia ( 378.9 ) Eye movement disorder, unspec. [en.wikipedia.org]
Infiltrative Ophthalmopathy Infiltrative Ophthalmopathy A patient with Graves disease manifests ocular signs, including widened palpebral fissures, lid retraction, strabismus, and exophthalmos. By permission of the publisher. [msdmanuals.com]
- Blepharitis
Blepharitis and corneal haze inboth eyes. Figure 4. Tears in the Descemet membraneand palpebral conjunctival hyperemia with papillary hypertrophy. [jamanetwork.com]
Blepharitis tends to be associated with greasiness of the skin and with dandruff. [britannica.com]
[…] has various causes, including meibomian gland disease, eyelid aperture disorders or lid/globe incongruity, blink disorders, and ocular surface disorders (Table 1). 2,3 The most common cause is meibomian gland dysfunction (MGD; also called posterior blepharitis [ajmc.com]
Pterygium ( 372.5 ) Conjunctival degenerations and deposits ( 372.6 ) Conjunctival scars ( 372.7 ) Conjunctival vascular disorders and cysts ( 372.72 ) Subconjunctival hemorrhage ( 372.81 ) Conjunctivochalasis ( 373 ) Inflammation of eyelids ( 373.0 ) Blepharitis [en.wikipedia.org]
- Anisocoria
NIH: National Eye Institute Anisocoria Chemosis Choroidal dystrophies Coloboma of the iris Epicanthal folds Episcleritis Eye and orbit ultrasound Eye burning - itching and discharge Eye pain Eye redness Fluorescein angiography Fluorescein eye stain Heterochromia [icdlist.com]
Other [ edit ] ( 379 ) Other disorders of eye ( 379.0 ) Scleritis and episcleritis ( 379.2 ) Disorders of vitreous body ( 379.24 ) Other vitreous opacities Vitreous floaters ( 379.4 ) Anomalies of pupillary function ( 379.41 ) Anisocoria ( 379.45 ) Argyll [en.wikipedia.org]
- Conjunctival Injection
Ocular motility disturbances Binocular diplopia Poor convergence (Moebius sign) Restriction of one or more extraocular muscles Lid retraction, also known as “thyroid stare” Joffroy sign: absent forehead creases during superior gaze Conjunctival injection [amboss.com]
Neurologic
- Headache
Diagnosis The diagnosis of Tolosa-Hunt syndrome has been codified by the International Headache Society. [rarediseases.org]
The most prevalent neurological disorders were tension-type headaches (about 1,500 million cases), migraine (about 1,000 million), medication overuse headaches (about 60 million), and Alzheimer's disease and other dementias (about 46 million cases). [news-medical.net]
The following findings are of particular concern: Eye pain or redness Headache Loss of vision Diplopia Fever Pulsating proptosis Neonatal proptosis Proptosis can be confirmed with exophthalmometry, which measures the distance between the lateral angle [merckmanuals.com]
Premenstrual syndrome, better known as PMS, is nearly a universal experience for women; the most common symptoms include bloating, fatigue, headaches, and mood swings. [girlsglobe.org]
In patients with orbital cellulitis, the development of headache, ophthalmoplegia, facial hypesthesia in regions innervated by V1 and V2, and/or seizures should raise suspicion for cavernous sinus thrombosis. [amboss.com]
- Dizziness
The most commonly reported adverse events were somnolence, dizziness and fatigue. [globenewswire.com]
Co-workers, family members, or significant others may feel dizzy trying to maintain. What did you say today? She is so mad that she won't even speak to you! Wait, now she is back; she's crying and depressed and requires you for emotional support. [psychotherapy.thementalhealth.clinic]
[…] patients, AF or supraventricular tachycardia due to atrioventricular (AV) nodal re-entry or Wolff-Parkinson-White syndrome have been reported.10 Pharmacological Testing Further investigation is needed in cases where there is a suspicion of BrS (syncope, dizziness [aerjournal.com]
(b) motor tension (restless fidgeting, tension headaches, trembling, inability to relax); (c) autonomic overactivity (lightheadedness, sweating, tachycardia or tachypnoea, epigastric discomfort, dizziness, dry mouth, etc.).” [ourworldindata.org]
- Seizure
Patients with Sunflower syndrome can also experience other types of seizures. These include absence seizures and generalized tonic-clonic seizures. [massgeneral.org]
Unlike benzodiazepines, ganaxolone exhibits anti-seizure and anti-anxiety activity via its effects on synaptic and extrasynaptic GABA A receptors. [globenewswire.com]
Then the doctor may ask for tests to examine the brain with: brain-imaging tests (for example, MRI or CT scans) electroencephalogram (if an individual has experienced seizures) can help identify areas of the brain that are not working properly by picking [yourgenome.org]
In patients with orbital cellulitis, the development of headache, ophthalmoplegia, facial hypesthesia in regions innervated by V1 and V2, and/or seizures should raise suspicion for cavernous sinus thrombosis. [amboss.com]
- Insomnia
Graves disease Eye symptoms: Eye pain, lacrimation, dry eyes, irritation, photophobia, ocular muscle weakness causing diplopia, vision loss caused by optic nerve compression Systemic symptoms: Palpitations, anxiety, increased appetite, weight loss, insomnia [merckmanuals.com]
Symptoms of an overactive thyroid, or hyperthyroidism, include weight loss, increased appetite, anxiety, insomnia and heart palpitations, including atrial fibrillation, a risk factor for stroke. [nytimes.com]
- Dystonia
Module 3 The diagnosis, etiology, epidemiology and treatment of dystonia Dystonia imprisons patients in a clinical cage. This knowledge module will introduce primary and secondary dystonia through their phenotype and physiological origins. [carrickinstitute.com]
333.7 Symptomatic torsion dystonia 333.8 Fragments of torsion dystonia 333.9 Other and unspecified 334 Spinocerebellar disease 334.0 Friedreich's ataxia 334.1 Hereditary spastic paraplegia 334.2 Primary cerebellar degeneration 334.3 Other cerebellar [en.wikipedia.org]
Workup
Microbiology
- Staphylococcus Aureus
aureus and varicella-zoster virus. [patient.info]
Treatment
[…] to Angular and Translational Movements Cerebellar based treatments Neostriatal based treatments Frontal lobe based treatments Parietal lobe based treatments Occipital lobe based treatments Substantia Nigra based treatments Mesencephalic based treatments [carrickinstitute.com]
“What this new study adds is a better understanding of what matters in regards to supervision of treatment. We are now able to improve treatment efficiency while also improving outcomes for every child.” [blogs.chapman.edu]
Treatment Treatment for bipolar disorder most often includes a combination of a mood-stabilizing drug and psychotherapy. Although drug treatment is primary, ongoing psychotherapy is important to help patients better cope with the condition. [expatriates.psyq.nl]
Treatment options vary, from hormonal treatment with birth control pills, to taking the class of antidepressants called SSRIs (selective serotonin reuptake inhibitors). [girlsglobe.org]
Last Updated & Reviewed By: Jacquelyn Ekern, MS, LPC on November 28, 2016 Published on EatingDisorderHope.com Tagged as: Treatment, Treatment Resources, International [eatingdisorderhope.com]
Prognosis
Prognosis Isolated DRS is a benign disorder which, if managed appropriately, results in excellent long term prognosis for vision. In some cases, amblyopia or loss of binocular single vision might develop. [orpha.net]
Scleritis - prognosis When scleritis originates from a systemic disorder, its course tends to follow that of the underlying problem. [patient.info]
Navy This article briefly describes the more common diseases of the eye and its associated structures, the methods used in examination and diagnosis, and the factors that determine treatment and prognosis. [britannica.com]
PMID: 23056030Free PMC Article Prognosis Ye P, Xu J, Luo Y, Su Z, Yao K BMC Med Genet 2020 Jan 22;21(1):16. doi: 10.1186/s12881-020-0951-3. [ncbi.nlm.nih.gov]
[…] head and neck, urogenital region, or extremities Minimally painful, rapidly increasing, gross swelling Orbital rhabdomyosarcoma Growing orbital mass that may be painful and have potential hemorrhage Proptosis or dysconjugate gaze Diagnosis Treatment Prognosis [amboss.com]
Etiology
The diagnosis, etiology, epidemiology and treatment of myoclonic syndromes This clinical learning module will explore the etiology, epidemiology, phenomenology and clinical approaches to the diagnosis and treatment of jerky movement disorders. [carrickinstitute.com]
Third, certain DED etiologies involve multiple mechanisms. [ajmc.com]
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. [icd10coded.com]
Graves ophthalmopathy Definition: Graves ophthalmopathy or orbitopathy (GO) (also known as thyroid-associated orbitopathy or ophthalmopathy, TAO) is an autoimmune condition that is generally associated with Graves disease Etiology TAO is not due to the [amboss.com]
Associations VATER syndrome The exact etiology is unknown and the disease is a non-hereditary disorder. [radiopaedia.org]
Epidemiology
The diagnosis, etiology, epidemiology and treatment of myoclonic syndromes This clinical learning module will explore the etiology, epidemiology, phenomenology and clinical approaches to the diagnosis and treatment of jerky movement disorders. [carrickinstitute.com]
Epidemiology Pathophysiology TSH autoantibodies are present in the orbital cavity; (eye socket) → bind TSH receptor antigen (autoimmune reaction) on cells; → lymphocytic infiltration into the orbital tissues → inflammation and release of cytokines from [amboss.com]
"The cross-national epidemiology of social anxiety disorder: Data from the World Mental Health Survey Initiative." [youtube.com]
“If you don’t think this disorder is driven by biological causes, then you wouldn’t think there was any use in doing epidemiological studies or trying to understand causal pathways.” [spectrumnews.org]
Pathophysiology
Although recent research has made progress in elucidating DED pathophysiology, currently there are no uniform diagnostic criteria. [ajmc.com]
Despite intense research efforts, as documented by about 5,000 publications on BrS, controversies still exist over its pathophysiology, risk stratification and care. [aerjournal.com]
Epidemiology Pathophysiology TSH autoantibodies are present in the orbital cavity; (eye socket) → bind TSH receptor antigen (autoimmune reaction) on cells; → lymphocytic infiltration into the orbital tissues → inflammation and release of cytokines from [amboss.com]
[…] manner with incomplete penetrance and variable expressivity[2] General Pathology Duane Retraction Syndrome results from an absent or dysplastic abducens motor neurons with aberrant innervations of the lateral rectus muscle by the oculomotor nerve.[7] Pathophysiology [eyewiki.aao.org]
Decreases in repolarizing outward K+ currents or increases in depolarizing inward sodium or calcium currents can lead to prolongation of the QT interval, thus representing a pathophysiological substrate for LQTS. [ahajournals.org]
Prevention
In the United States, cigarette smoking is the leading cause of preventable disease and accounts for about 1 in every 5 deaths, according to the Centers for Disease Control and Prevention. [medicaldaily.com]
World leaders have committed to “prevention and treatment of noncommunicable diseases, including behavioral, developmental and neurological disorders, which constitute a major challenge for sustainable development.” [bhjustice.org]
Treatment is immediate lateral canthotomy followed by: Monitoring with possible inpatient hospitalization with elevation of the bed to 45° Reversal of any coagulopathy Prevention of further increasing intraocular pressure (preventing or minimizing pain [merckmanuals.com]
[…] diet can prevent weight loss and may have a positive impact on other symptoms. [yourgenome.org]
While a little bit of anxiety can be beneficial by helping us keep safe, people with untreated anxiety disorders experience overwhelming, uncontrollable feelings of dread or fear that can interfere with daily life and prevent them from doing the things [chconline.org]