(Lewis, 91) Classical phenylketonuria presents in infancy with developmental delay; seizures; skin hypopigmentation; eczema; and demyelination in the central nervous system. [richardsonthebrain.com]

Congenital cortical blindness is most often caused by perinatal ischemic stroke, encephalitis, and meningitis. [icd.codes]

[…] hypoxic ischemic encephalopathy (HIE) (in the term born infant) periventricular leukomalacia (PVL) (in the preterm infant) traumatic brain injury due to shaken baby syndrome and accidental head injuries neonatal hypoglycemia, infections (e.g. viral meningitis [childrenshospital.org]

[…] perinatal hypoxia ischemia ("hypoxia": a lack of sufficient oxygen in the body cells or blood; "ischemia": not enough blood supply to the brain), developmental brain defects, head injury, hydrocephalus, and infections of the central nervous system, such as meningitis [tsbvi.edu]

Common causes CVI in infants and young children include: hypoxic ischemic encephalopathy (HIE) (in the term born infant) periventricular leukomalacia (PVL) (in the preterm infant) traumatic brain injury due to shaken baby syndrome and accidental head [childrenshospital.org]

Cortical Visual Impairment can be the result of a variety of different medical causes including hypoxic ischemic encephalopathy (HIE) in full-term babies, periventricular leukomalacia (PVL) in premies, traumatic brain injury, epilepsy and other causes [wonderbaby.org]

Zoom Posterior reversible encephalopathy Posterior reversible encephalopathy creates a clinical picture associating seizures, cortical blindness, headache, nausea and vomiting, awareness disorders, arterial hypertension and kidney failure. [em-consulte.com]

Cioni G, Fazzi B, Ipata AE, Canapicchi R, van Hof-van Duin J.Correlation between cerebral visual impairment and magnetic resonance imaging in children with neonatal encephalopathy. Developmental Medicine and Child Neurology 1996;38(2):120-132. [child-encyclopedia.com]

Confusing diagnostic entities include: delayed visual maturation autism spectrum disorders severe bilateral central scotomata (with eccentric fixation) dyskinetic eye movement disorders profound mental retardation Eye examination findings The eye examination [childrenshospital.org]

During early development, visual motor disturbances are more evident than at later ages. Aspects of abnormal reaching and visual avoidance may be affected by abnormal sensory integration and motor output difficulties. [childrenshospital.org]