Presentation
To the best of our knowledge, bizarre atypical presentation of sporotrichosis, in an immunocompetent is a rare presentation. [e-ijd.org]
A 40-year-old Caucasian man presented to the dermatology clinic at Baylor College of Medicine, Houston, Texas, in February 2003, for the evaluation of three nonhealing ulcers. [ncbi.nlm.nih.gov]
She was commenced on itraconazole 200 mg daily for treatment of lymphocutaneous sporotrichosis, the most common presentation of the disease. She re-presented to our clinic 12 months later with very poor compliance. [medicaljournals.se]
[…] and present with pneumonia They may or may not have skin lesions Bones and joint disease Patients typically present with a subacute or chronic inflammatory arthritis involving one or more joints They may or may not have skin lesions Disseminated disease [dermnetnz.org]
Entire Body System
- Weight Loss
Symptoms of disseminated sporotrichosis include: Weight loss Loss of appetite or anorexia Bony lesions This form of the disease can lead to or be accompanied by arthritis and osteomyelitis or infection of the bones. [healthinplainenglish.com]
It may cause breathing difficulties, chest pain, cough, fever, fatigue, and unintentional weight loss. Sporotrichosis can also be spread to humans from infected animals (especially cats) through scratches and bites. [healthline.com]
The infection can spread to joints and bones (called osteoarticular sporotrichosis) as well as the central nervous system and the brain (called sporotrichosis meningitis).The symptoms of disseminated sporotrichosis include weight loss, anorexia, and appearance [en.wikipedia.org]
Pulmonary disease may present with a productive cough, occasionally with haemoptysis, along with fever and weight loss. [fidssa.co.za]
Deep infection with sporotrichosis is more difficult to recognize and has few distinguishing characteristics,4,1019 although patients with pulmonary involvement may have signs of systemic illness with nonproductive coughs, weight loss, and malaise.20,21 [healio.com]
- Surgical Procedure
Table TABLE SURGICAL PROCEDURES Ten of 12 patients with joint involvement had residual functional impairment. Three of four patients who underwent synovectomy had activity-related discomfort and limited active range of motion. [healio.com]
Respiratoric
- Pneumonia
Discomfort Secondary skin infections (such as staph or strep) People with a weakened immune system may develop: Arthritis Bone infection Complications from medicines -- amphotericin B can have serious side effects Lung and breathing problems (such as pneumonia [nlm.nih.gov]
Immunodepressed individuals develop disseminated infections and/or pneumonia that can cause shortness of breath, cough, and fever. [medicinenet.com]
With this type you many get pneumonia, shortness of breath, fever, and coughing. [austincc.edu]
- Cough
Immunodepressed individuals develop disseminated infections and/or pneumonia that can cause shortness of breath, cough, and fever. [medicinenet.com]
In March 2000, the patient had complained of cough and shortness of breath. A purified protein derivative (PPD) (Mantoux text) was negative. [ncbi.nlm.nih.gov]
Symptoms of pulmonary sporotrichosis include: Cough Holes and nodules in the lungs Swollen hilar lymph nodes of the lungs Pleural effusion or pooling of blood or lymph fluids into the pleural cavity. [healthinplainenglish.com]
It may cause breathing difficulties, chest pain, cough, fever, fatigue, and unintentional weight loss. Sporotrichosis can also be spread to humans from infected animals (especially cats) through scratches and bites. [healthline.com]
Symptoms of pulmonary sporotrichosis include productive coughing, nodules and cavitations of the lungs, fibrosis, and swollen hilar lymph nodes. [en.wikipedia.org]
- Respiratory Distress
Amphotericin B is the treatment of choice for life-threatening blastomycosis including acute respiratory distress syndrome and CNS disease. 5 Patients with cavitary pulmonary lesions or with persistently positive respiratory cultures may require a longer [doi.org]
- Productive Cough
Symptoms of pulmonary sporotrichosis include productive coughing, nodules and cavitations of the lungs, fibrosis, and swollen hilar lymph nodes. [en.wikipedia.org]
Pulmonary disease may present with a productive cough, occasionally with haemoptysis, along with fever and weight loss. [fidssa.co.za]
- Painful Cough
It may cause breathing difficulties, chest pain, cough, fever, fatigue, and unintentional weight loss. Sporotrichosis can also be spread to humans from infected animals (especially cats) through scratches and bites. [healthline.com]
Cardiovascular
- Chest Pain
It may cause breathing difficulties, chest pain, cough, fever, fatigue, and unintentional weight loss. Sporotrichosis can also be spread to humans from infected animals (especially cats) through scratches and bites. [healthline.com]
Musculoskeletal
- Arthritis
Any case of intractable arthritis or skin ulcers, which does not improve, despite adequate immunosuppressive therapy, is likely to be suspicious of sporotrichosis. [ncbi.nlm.nih.gov]
Body-wide (systemic) sporotrichosis can cause lung and breathing problems, bone infection, arthritis, and infection of the nervous system. The health care provider will examine you and ask about your symptoms. [nlm.nih.gov]
Skin
- Ulcer
In addition to the nonhealing ulcer on his left forearm, which he had acquired several months earlier, he had also developed a 3.0 cm ulcer on his right arm and a 3.0 cm ulcer on his central back. The patient refused biopsies at this visit. [ncbi.nlm.nih.gov]
History of excursion to Amazon rain forest 1-month prior to the onset of ulceration was present. [e-ijd.org]
Any case of intractable arthritis or skin ulcers, which does not improve, despite adequate immunosuppressive therapy, is likely to be suspicious of sporotrichosis. [jstage.jst.go.jp]
Small ulcers appear as lines on the skin as the infection moves up an arm or leg. These sores do not heal unless they are treated, and they may last for years. The sores may sometimes drain small amounts of pus. [nlm.nih.gov]
- Skin Lesion
Fixed sporotrichosis is isolated to the skin lesions mentioned above. Disseminated sporotrichosis begins as skin lesions and will progress into a systemic disease. [aocd.org]
[…] and present with pneumonia They may or may not have skin lesions Bones and joint disease Patients typically present with a subacute or chronic inflammatory arthritis involving one or more joints They may or may not have skin lesions Disseminated disease [dermnetnz.org]
Given the patient's previous diagnosis of pulmonary sarcoidosis, it was thought that the skin lesions might represent ulcerative cutaneous sarcoidosis. Pyoderma gangrenosum was also considered to be a likely diagnosis. [ncbi.nlm.nih.gov]
All of the 36 patients with primary lymphocutaneous sporotrichosis had nonhealing ulcerated skin lesions, 26 had multiple lesions, and 18 had associated lymphangitis. [healio.com]
Meningeal and pulmonary sporotrichosis are difficult to diagnose and treat, with less positive outcomes. 2015 review: Global Epidemiology of Sporotrichosis Images Appearance of a nodule in the skin lesion which is an early feature of sporotrichosis An [life-worldwide.org]
- Subcutaneous Nodule
Clinically, this form is manifested as a chain of subcutaneous nodules along the course of lymphatics draining a primary skin lesion that may be nodular and ulcerated. [histopathology-india.net]
Sporothrix brasiliensis isolates were recovered from cultures of subcutaneous nodules and mitral valve fragments. Species identification was based on classical and molecular methods. [ajtmh.org]
It is usually characterized by skin ulcers and subcutaneous nodules along lymphatic channels. It rarely spreads to involve bones, lungs, joints, or muscles. The most severe symptoms are observed in patients with AIDS. [medical-dictionary.thefreedictionary.com]
He developed multiple subcutaneous nodules and an ulcer over the right thigh even after 6 weeks of treatment. Thus, saturated solution of potassium iodide (SSKI) was added with complete clearance of the lesions in 10 weeks. [e-ijd.org]
nodules that progress proximally along lymphatic channels (lymphocutaneous sporotrichosis). [emedicine.com]
- Skin Ulcer
Any case of intractable arthritis or skin ulcers, which does not improve, despite adequate immunosuppressive therapy, is likely to be suspicious of sporotrichosis. [ncbi.nlm.nih.gov]
The disease causes ulcers on the skin that are painless but do not heal, as well as nodules or knots in the lymph channels near the surface of the body. [medical-dictionary.thefreedictionary.com]
[…] effects Lung and breathing problems (such as pneumonia ) Brain infection ( meningitis ) Widespread (disseminated) disease Make an appointment with your provider if you develop persistent skin lumps or skin ulcers that do not go away. [nlm.nih.gov]
- Skin Disease
Skin disease is the most common. [dermnetnz.org]
The condition is not figured by Smith in his Atlas of Skin Diseases in the Tropics, nor does Loewenthal mention it in his account of the diseases of the Skin in negroes.1 Most of the reported cases have come from France and the United States. [jamanetwork.com]
Related Treatment of Skin Disease Comprehensive Therapeutic Strategies 4e [clinicalgate.com]
Neurologic
- Irritability
Host Disease Granuloma Annualare Graves’ Disease and Pretibial Myxedema Hidradenitis Suppurativa (Acne Inversa) Irritant Contact Dermatitis Keratosis Pilaris Langerhans Cell Histiocytosis: Presentation in Childhood Langerhans Cell Histiocytosis: Eosinophilic [euro-libris.ro]
Treatment
Terbinafine was well tolerated and the frequency of drug‐related AEs was slightly higher in the 1000 mg treatment group. Both doses of terbinafine were well‐tolerated and effective for the treatment of sporotrichosis. [doi.org]
However, the benefits and adverse reactions of these treatments have not yet been systematically reviewed. Objectives: To assess the effects of oral potassium iodide for the treatment of sporotrichosis. [cochrane.org]
[…] reports and nonrandomized treatment trials. [web.archive.org]
Reference is easy thanks to a unique 3-part structure covering general aspects of treatment; reviews of every agent; and details of treatments of particular infections. [books.google.com]
The optimal treatment of systemic sporotrichosis in HIV-positive patients is as yet unknown. [ncbi.nlm.nih.gov]
Prognosis
(Outcomes/Resolutions) The prognosis of Sporotrichosis is generally good with appropriate treatment Disseminated Sporotrichosis may become fatal for patients with weak immune systems. [dovemed.com]
Outlook and prognosis Excellent for cutaneous and lymphocutaneous disease, with cure rates exceeding 95%. [life-worldwide.org]
Outlook (Prognosis) With treatment, full recovery is likely. Disseminated sporotrichosis is more difficult to treat and requires several months of therapy. Disseminated sporotrichosis can be life-threatening for people with a weakened immune system. [ufhealth.org]
The prognosis for patients with lymphocutaneous sporotrichosis is generally regarded as excellent3,4,31"33 with little anticipated functional compromise or cosmetic deformity. [healio.com]
[2, 3] Age Sporotrichosis may occur in any age, but it typically affects adults, reflecting their more frequent participation in veterinary care, gardening, woodworking, and occupational situations in which puncture wounds may occur. [2, 3, 6, 7, 8] Prognosis [emedicine.com]
Etiology
Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. [icd10coded.com]
Incidence of specific etiology and role of methods for specific etiologic diagnosis of primary acute pericarditis. Am J Cardiol 1995; 75:378-382 Chapter 9 SPECIFIC PERICARDIAL DISORDERS Congenital malformations and acquired diseases 1. [books.google.es]
Although consistent with sarcoidosis, these findings were insufficient to exclude other etiologies, including disseminated fungal infection. [ncbi.nlm.nih.gov]
(Etiology) Sporotrichosis is a skin infection caused by the fungus Sporothrix schenckii This fungus is found on rose thorns, hay, sphagnum moss, twigs and decaying vegetables The fungus enters the skin through cuts or scrapes made by thorns, barbs, pine [dovemed.com]
Sporotrichosis By: Brittney Majefski Etiologic agent: Sporothrix schenckii(3). General characteristics : Sporotrichosis is a fungal disease that is scene all over the world. [austincc.edu]
Epidemiology
Meningeal and pulmonary sporotrichosis are difficult to diagnose and treat, with less positive outcomes. 2015 review: Global Epidemiology of Sporotrichosis Images Appearance of a nodule in the skin lesion which is an early feature of sporotrichosis An [life-worldwide.org]
Dixon, Nosocomial aspergillosis: Environmental microbiology, hospital epidemiology, diagnosis and treatment, European Journal of Epidemiology, 1989, 5, 2, 131 CrossRef 19 David W. Denning, Richard M. Tucker, Linda H. Hansen, David A. [onlinelibrary.wiley.com]
Flavio Queiroz-Telles, Marcio Nucci, Arnaldo Lopes Colombo, Angela Tobón and Angela Restrepo, Mycoses of implantation in Latin America: an overview of epidemiology, clinical manifestations, diagnosis and treatment, Medical Mycology, 49, 3, (225), (2011 [doi.org]
[Sporotrichosis: prevalence, clinical and epidemiological features in a reference center in Colombia]. Rev Iberoam Micol. 2010 Jun 30. 27(2):75-9. [Medline]. Barros MB, de Almeida Paes R, Schubach AO. Sporothrix schenckii and Sporotrichosis. [emedicine.com]
病原体 Sporothrix schenckii [GN: ssck ] 治療薬 テルビナフィン塩酸塩 [DR: D02219 ] イトラコナゾール [DR: D00350 ] リンク ICD-11: 1F2J ICD-10: B42 MeSH: D013174 MedlinePlus: 001338 文献 PMID: 25526781 著者 Chakrabarti A, Bonifaz A, Gutierrez-Galhardo MC, Mochizuki T, Li S タイトル Global epidemiology [genome.jp]
Pathophysiology
& Vitamin K Antagonists: Anticoagulation Affects on the Clotting Cascade Wilson’s Disease Section 9 - Genodermatoses and Syndromes Addison’s Disease Amyloid Basal Cell Nevus Syndrome Carney Complex Cushing's Syndrome and Disease Cushing's Syndrome: Pathophysiology [euro-libris.ro]
This contributed significantly to the current understanding of Sporothrix schenckii, its growth patterns, and its mechanisms of dissemination. [2, 3] Pathophysiology Sporotrichosis infections can be either cutaneous or extracutaneous. [emedicine.com]
A thorough review of the topic was published by Barros et al in 2011. [5] Pathophysiology Infection with the dimorphic soil fungus S schenckii is usually acquired from organic matter through cutaneous inoculation. [emedicine.medscape.com]
Prevention
Response to treatment is variable and chronic suppressive therapy is probably needed to prevent relapse. [ncbi.nlm.nih.gov]
How Can I Prevent Sporotrichosis? There is no vaccine to prevent sporotrichosis. [medicinenet.com]
Prevention of this disease includes wearing long sleeves and gloves while working with soil, hay bales, rose bushes, pine seedlings, and sphagnum moss. Also, keeping cats indoors is a preventative measure. [en.wikipedia.org]
The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. [cdc.gov]