We present a 35-year-old woman, which presented with flexural hyperpigmentation considerate as acanthosis nigricans. [ncbi.nlm.nih.gov]

• Asymptomatic

  We report a 47-year-old woman who presented with asymptomatic reticulate hyperpigmentations on the neck, lateral face, axillae, trunk, inguinal areas, and dorsa of both hands and feet. [ncbi.nlm.nih.gov]

  Symptoms - Dowling-Degos disease * Asymptomatic * Discolored spots on skin * Mental retardation * Trichilemmal cysts * Progressive pigmentation of armpits Causes - Dowling-Degos disease * See Pathophysiology. * DDD may coexist with hidradenitis suppurativa [checkorphan.org]

  Institute of Medical Sciences, Hubli - 580 022, Karnataka India Source of Support: None, Conflict of Interest: None DOI: 10.4103/0378-6323.53139 Dowling Degos disease is a rare condition inherited as autosomal dominant trait characterized by numerous, asymptomatic [ijdvl.com]

  A 19-year-old unmarried female presented with asymptomatic pigmented spots on the face, flexural areas such as axillae, groins, antecubital fossae, popliteal fossae and dorsum of hands since 8 years. [jcasonline.com]

• Axillary Lesion

  Another interesting point was that the biopsied specimens from the abdomen, neck, and axillary lesions showed somewhat different histopathologic features from typical DDD, suggesting an evolutional sequence. [ncbi.nlm.nih.gov]

  Histopathology axillary lesion was also similar except for features of follicular plugging [Figure 3] a and b. [e-ijd.org]

  lesion demonstrating filiform elongation of the rete ridges, hyperpigmentation of basilar keratinocytes, and clusters of melanocytes at the tip of the rete ridges along with follicular plugging (H and E, 10) (b) High-power view of the same (H and E, [slideplayer.com]

• Follicular Plugging

  Histopathology axillary lesion was also similar except for features of follicular plugging [Figure 3] a and b. [e-ijd.org]

  These threadlike growths of the epidermis have the appearance of "antlers" and generally involve the follicle with a follicular plug. A perivascular lymphohistiocytic infiltrate in the papillary dermis and pseudo-horny cysts can also be observed. [slideplayer.com]

  Follicular infundibulum may be involved and in some cases there is follicular plugging. [1], [2] In the present study, all three cases had typical triad and histopathologic features. [idoj.in]

• Macula

  Las lesiones consistian en maculas de color marron oscuro. Tambien presentaba hidradenitis supurativa en las axilas y las ingles. Una hija de la paciente tenia una pigmentacion reticulada similar que afectaba a las axilas. [scinapse.io]

  Some patients complain of itching in the macula. These lesions do not change with sun exposure. [slideplayer.com]

  Syndrome Methylation Panel Macrocephaly and Overgrowth Syndromes: Sequencing Panel Macrocephaly Deletion/Duplication panel Macrocephaly Panel Macrocephaly Sequencing Panel Macrocephaly, Panel Massive Sequencing (NGS) 16 Genes Macrocephaly: Sequencing Panel Macula [genetests.org]

• Axillary Freckling

  Our differential diagnoses included Dowling Degos disease, acanthosis nigricans, multiple basal cell papillomas, epidermal nevi and axillary freckles of neurofibramatosis. [edoj.org.eg]

  Crowe FW: Axillary freckling as a diagnostic aid in neurofibromatosis. Ann Intern Med 1964;61:1142–1143. Amer M, Mostafa FF, Nasr AN: Lentiginous macules and patches of neurofibromatosis (an approach to better terminology). [karger.com]

• Plantar Hyperkeratosis

  Online J Onychodystrophy of finger nails Plantar hyperkeratosis 48 Dermatopathia pigmentosa reticularis I. Drm. [slideplayer.com]

• Facial Scar

  Dowling-Degos disease (DDD) is a rare genetic disease of the skin (reticulate pigmented anomaly), clinically characterized by flexural brown pigmented reticulate macules, comedo-like papules on the back, neck and pitted perioral or facial scars. [ncbi.nlm.nih.gov]

  He also had multiple nonacne facial scars predominantly on the nose and malar areas. The patient had overlapping features of RAPK and DDD. In addition, he also had hypopigmented macules and acneiform facial scars. [e-ijd.org]

  原文摘要 Dowling-Degos disease (DDD) is a rare genetic disease of the skin (reticulate pigmented anomaly), clinically characterized by flexural brown pigmented reticulate macules, comedo-like papules on the back, neck and pitted perioral or facial scars. [xkeyan.com]

The laser treatment led to a good clinical result. Our case suggest that treatment with the Er:YAG laser might be a successful strategy in Dowling-Degos disease. [ncbi.nlm.nih.gov]

Desmoderm Skin Clinic Dermatologist - Specializes in Treatment of Dowling-Degos Disease Aruna Asif Ali Marg, Landmark:Near Fortis Hospital, Vasant Kunj, Delhi Vasant Kunj Elan Hair & Skin Clinic Dermatologist - Specializes in Treatment of Dowling-Degos [lybrate.com]

Prognosis - Dowling-Degos disease Not supplied. Treatment - Dowling-Degos disease Not supplied. Resources - Dowling-Degos disease Not supplied. [checkorphan.org]

Because of its favorable prognosis, differentiation of this benign disorder from acanthosis nigricans, a cutaneous marker of possible or existing internal malignant disease, is highly important. [jamanetwork.com]

Differentiation from acanthosis nigricans is important because of its favorable prognosis. Onset is most often in the 30- to 40-year age range. The disease is slowly progressive, but not life threatening. [cags.org.ae]

McKee's Pathology of the Skin is the most complete, in-depth resource on dermatopathology, covering etiology, pathogenesis, disease mechanisms, and recent genetic, molecular, and basic science data. Drs. J. [books.google.com]

(Etiology) Dowling-Degos Disease is most commonly inherited from a single parent (in an autosomal dominant manner); however, the condition may also develop sporadically. [dovemed.com]

Age at disease onset is very important in MS etiologic studies and ought to have been used as a matching variable to potentially control for bias. [ncbi.nlm.nih.gov]

Etiology See Pathophysiology. Dowling-Degos disease (reticulate pigmented anomaly) may coexist with hidradenitis suppurativa. [emedicine.medscape.com]

Surveillance: Inventorying Gaps and Commonalities Across the Universe of Surveillance Systems Aaron KitePowell Evaluating the Utility of HealthMap as a Supplementary Surveillance Tool Michael Paul Tracking Public Awareness of Influenza Through Twitter Eric Lau Epidemiological [healthmap.org]

Meta-analysis of observational studies in epidemiology: a proposal for reporting. Meta-analysis Of Observational Studies in Epidemiology (MOOSE) group. [ncbi.nlm.nih.gov]

This report defines the prevalence of genital colonization in a large population of women, characterizes the women with S. aureus, and describes epidemiologic features of genital carriage. ‎ Página 50 - Lautenschlager S, Eichmann A. [books.google.es]

Relevant External Links for POFUT1 Genetic Association Database (GAD) POFUT1 Human Genome Epidemiology (HuGE) Navigator POFUT1 Atlas of Genetics and Cytogenetics in Oncology and Haematology: POFUT1 No data available for Genatlas for POFUT1 Gene Modification [genecards.org]

The ai mai mult Journal of the American Academy of Dermatology 25 Decembrie 2013 22:00 Background: The incidence of lentigo maligna (LM) may be increasing, but no population-based epidemiologic studies have been performed to our knowledge.Objective: We [ww.paginamedicala.ro]

Symptoms - Dowling-Degos disease * Asymptomatic * Discolored spots on skin * Mental retardation * Trichilemmal cysts * Progressive pigmentation of armpits Causes - Dowling-Degos disease * See Pathophysiology. * DDD may coexist with hidradenitis suppurativa [checkorphan.org]

It can be considered an acantholytic variant of Dowling-Degos disease. [ 8 ] The pathophysiology of Dowling-Degos disease is related to a genetic defect. [derm101.com]

[…] the chances of developing acne. [3] Comedones may be more common in some ethnic groups. [3] [7] People of Latino and recent African descent may experience more inflammation in comedones, more comedonal acne, and earlier onset of inflammation. [3] [7] Pathophysiology [en.wikipedia.org]

Etiology See Pathophysiology. Dowling-Degos disease (reticulate pigmented anomaly) may coexist with hidradenitis suppurativa. [emedicine.medscape.com]

Taiwanese Woman with Dowling-Degos Disease: An Electron Microscopic Study with Pathophysiological Significance Yu, Wei-tai ; Su, Yung-shun ; Lee, Chih-hung Dermatologica Sinica 32:1 2014.03[民103.03] 頁33-36 7. [readopac2.ncl.edu.tw]

Prevention - Dowling-Degos disease Not supplied. Diagnosis - Dowling-Degos disease Not supplied. Prognosis - Dowling-Degos disease Not supplied. Treatment - Dowling-Degos disease Not supplied. Resources - Dowling-Degos disease Not supplied. [checkorphan.org]

How can Dowling-Degos Disease be Prevented? Currently, there are no specific methods or guidelines to prevent Dowling-Degos Disease, since it is a genetic condition. [dovemed.com]

Michael Johansson, Center for Disease Control and Prevention Jean Paul Chretien, Division of Integrated Biosurveillance - US Navy 10h30 - 11h Break Coffee and snacks 11h - 12h15 Rapid Fire Talks 12h15 - 13h Closing Keynote Deborah Estrin, Cornell Tech [healthmap.org]

The patient's clinical photograph prevented us from making an embarrassing and uninformed diagnosis. Thanks to the referring dermatologist for providing such a beautiful clinical photograph. [dermpathmd.com]