Edit concept Question Editor Create issue ticket

Drug-induced Cardiomyopathy

Dilated Cardiomyopathy Secondary to Drug


Presentation

  • Congestive heart failure (CHF) was not present before BMT. Right heart pressures were monitored by a pulmonary arterial balloon catheter system (Swan-Ganz catheter). After BMT, she had severe CHF, which was controlled using pimobendan and amrinone.[ncbi.nlm.nih.gov]
  • From the initial two presentations it was thought to be and managed as a chest infection, and a perfusion ventilation scan was done to rule out pulmonary embolism.[casereports.bmj.com]
  • Case presentation A 38-year-old male presented with shortness of breath, chest tightness and sweating which started after he used intravenous crystal meth the day before presentation.[bjmp.org]
  • Eight weeks prior to presentation he had an influenza-like illness. He presented with a 2-week history of shortness of breath, ankle swelling and orthopnoea.[nzma.org.nz]
Congestive Heart Failure
  • Congestive heart failure (CHF) was not present before BMT. Right heart pressures were monitored by a pulmonary arterial balloon catheter system (Swan-Ganz catheter). After BMT, she had severe CHF, which was controlled using pimobendan and amrinone.[ncbi.nlm.nih.gov]
  • heart failure (chf) with cardiomyopathy Congestive heart failure due to cardiomyopathy Congestive obstructive cardiomyopathy Dilated cardiomyopathy Dystrophic cardiomyopathy Endomyocardial disease Familial cardiomyopathy Familial restrictive cardiomyopathy[icd9data.com]
  • heart failure , and even shock.[hopkinsmedicine.org]
  • Congestive heart failure due to dilated cardiomyopathy is an unusual cause of shortness of breath in young patients.[nzma.org.nz]
  • heart failure are depicted in Fig 3 .[pediatrics.aappublications.org]
Crying
  • I am crying right now,because My daughter is on the same path,and the system is just not able to give our loved ones the kind of help they truly need.The mental health system has taken some real cuts in from the gov't and our children are suffering. to[medhelp.org]
Constipation
  • Trihexyphenidyl Side effect control 1.Pantoprazole anxiety, arthralgia, asthenia, back pain, bronchitis, chest pain, constipation, cough increased, dizziness, dyspepsia, dyspnea, flu syndrome, gastroenteritis, gastrointestinal disorder, hyperlipemia,[medhelp.org]
Heart Disease
  • Mainly based on some drugs such as the above-mentioned antineoplastic drugs, antipsychotic or antidepressants before no evidence of heart disease, medication after arrhythmia, heart enlargement, signs of cardiac dysfunction, and can not use other heart[healthfrom.com]
  • Understand Your Risk for Cardiomyopathy Symptoms and Diagnosis of Cardiomyopathy Prevention and Treatment of Cardiomyopathy Cardiomyopathy in Children Learn more: Family History and Heart Disease Alcohol and Heart Disease Cocaine, Marijuana and Other[heart.org]
  • Familial and senile amyloid heart disease are related to the overproduction of transthyretin. Myocardial amyloid heart disease is confirmed by EMB.[clevelandclinicmeded.com]
  • Drug- induced fibrotic valvular heart disease. Lancet 2009;374:577-85. Zanettini R, Antonini A, Gatto G, Gentile R, Tesei S, Pezzoli G. Valvular heart disease and the use of dopamine agonists for Parkinson's disease. N Engl J Med 2007;356:39-46.[nps.org.au]
  • Secondary cardiomyopathy – Caused by a medical condition (such as hypertension, valve disease, congenital heart disease, coronary artery disease, or toxins/medications). Some of these conditions can be treated, which can prevent the muscle affected.[my.clevelandclinic.org]
Cardiomegaly
  • Cardiomyopathy Cardiomegaly 1040g with hypertrophic and dilated ventricles 'Hypertensive change of coronary arteries and myocardium Morbid obesity BMI 50 Organomegaly Cardiomegaly Hepatosplenomegaly with fatty change of live Based on anatomic findings[medhelp.org]
  • Chest x-ray shows cardiomegaly, usually of all chambers. Pleural effusion, particularly on the right, often accompanies increased pulmonary venous pressure and interstitial edema.[merckmanuals.com]
  • Common abnormalities seen on the chest radiograph include cardiomegaly, interstitial edema, pleural effusion(s), and evidence of previous sternotomy (sternal wires).[clevelandclinicmeded.com]
Orthostatic Hypotension
  • hypotension, sinus tachycardia, atrioventricular block, etc., because the drug can inhibit cytochrome P450 , Combined with other drugs may affect the metabolism of other drugs or increase the response to cardiovascular. 3.[healthfrom.com]
Dysesthesia
  • Omeprazole Nervous System/Psychiatric Psychic disturbances including depression, agitation, aggression, hallucinations, confusion, insomnia, nervousness, tremors, apathy, somnolence, anxiety, dream abnormalities; vertigo; paresthesia; and hemifacial dysesthesia[medhelp.org]
Unable to Walk
  • He was rushed to hosp 9 yrs ago unable to walk or talk eyes rolling upwards and salivating heavily. No dr admit to anything, his social worker disappeared. 3 solicitors would not take on the case. it is all wrong. system corrupt.[medhelp.org]

Workup

  • An extensive infectious and rheumatologic workup was negative.[oatext.com]
Myocardial Fibrosis
  • The combination of myocyte injury and necrosis associated with myocardial fibrosis results in impaired mechanical function.[clevelandclinicmeded.com]

Treatment

  • Treatment Treatment of drug - induced cardiomyopathy Department of Internal Medicine: Department of Internal Medicine Treatment: drug treatment supportive treatment Treatment cycle: 1-3 months Cure rate: 70% Commonly used drugs: injection with levocaine[healthfrom.com]
  • CQ-induced or HCQinduced autophagic vacuolar cardiomyopathy is not universally fatal, but successful treatment requires early detection.[ohsu.pure.elsevier.com]
  • Keywords Acrolein, Cardiomyocytes, Nitrogen Mustards, Poly (ADP-ribose) Polymerase Abstract Drug-induced cardiotoxicity has resulted in a thorough evaluation of patient doses, treatments, and rehabilitation.[scholarcommons.usf.edu]
  • Patients whose dilated cardiomyopathy is well-compensated with treatment may be stable for many years.[merckmanuals.com]
  • There were cases of cardiomyopathy associated with clozapine occurring after 3 years of treatment, with a mean duration of treatment of 12 months. 1 In conclusion, we have presented two cases of quetiapine-associated cardiomyopathy, one of whom died.[nzma.org.nz]

Prognosis

  • (B) prognosis The disease if the timely diagnosis, disable allergens and the use of symptomatic treatment, the general prognosis is good, most patients can be completely back to normal.[healthfrom.com]
  • Prognosis and Recurrence The long-term prognosis for patients with stress cardiomyopathy appears to be excellent. The heart returns to normal within a few weeks with no permanent damage.[hopkinsmedicine.org]
  • Prognosis Prognosis of dilated cardiomyopathy generally has been poor, although prognosis has improved with current management regimens (eg, use of beta-blockers, angiotensin-converting enzyme [ACE] inhibitors, mineralocorticoid receptor antagonists,[merckmanuals.com]
  • Prognosis and Treatment If a person who has been diagnosed with alcohol cardiomyopathy has severe heart damage, the prognosis for the condition tends to be poor.[dualdiagnosis.org]
  • Identification of these areas and restoration of their perfusion through revascularization might improve the ejection fraction and long-term prognosis.[clevelandclinicmeded.com]

Etiology

  • Introduction Etiology Prevention Complication Symptom Examine Diagnosis Treatment Basic Nursing Introduction Brief introduction of drug - induced cardiomyopathy Drug-induced cardiomyopathy Patients receiving certain medications, due to the toxic effects[healthfrom.com]
  • Use Additional Use Additional Help Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology.[icd10data.com]
  • After an extensive negative workup, the underlying etiology of the cardiomyopathy was postulated to be due to Anabolic Androgenic Steroids abuse.[oatext.com]
  • May 23, 2011 Coding for Cardiomyopathy For The Record Vol. 23 No. 10 P. 27 Cardiomyopathy is a progressive disease of the heart muscle with no known etiology. The condition makes it difficult for the heart to pump blood throughout the body.[fortherecordmag.com]
  • Takotsubo cardiomyopathy: etiology, diagnosis, and optimal management. Research Reports in Clinical Cardiology . 2014;5:297-303. Annette Lynn Ferguson, RN, MS, CNE is an Assistant Professor at Ohio University Southern in Ironton, Ohio.[americannursetoday.com]

Pathophysiology

  • Pathophysiology Dilated cardiomyopathy represents the final common morphologic outcome of various biologic insults. The combination of myocyte injury and necrosis associated with myocardial fibrosis results in impaired mechanical function.[clevelandclinicmeded.com]
  • Pathophysiology As a primary myocardial disorder, the myocardial dysfunction of dilated cardiomyopathy occurs in the absence of other disorders that can cause dilated myocardium, such as severe occlusive coronary artery disease or conditions that involve[merckmanuals.com]
  • Cocaine cardiotoxicity: a review of the pathophysiology, pathology, and treatment options. Am J Cardiovasc Drugs . 2009;9:177-196. 19. Schwartz B, Rezkalla S, Kloner RA. Cardiovascular effects of cocaine. Circulation . 2010;122:2558-2569. 20.[uspharmacist.com]
  • View Article PubMed Google Scholar Barry E, Alvarez J, Miller T, Lipshultz S: Anthracycline-induced cardiotoxicity: course, pathophysiology, prevention and management. Expert Opinion. 2007, 8: 1039-1058. 10.1517/14656566.8.8.1039.[jcmr-online.biomedcentral.com]

Prevention

  • Now in its second edition, this popular and essential comprehensive resource provides a detailed analysis of how to identify, prevent, and manage drug-induced diseases. Edited by James E. Tisdale and Douglas A.[books.google.com]
  • Prevention Prevention of drug - induced cardiomyopathy 1. For patients with allergic constitution, especially in the past have allergies to drugs, should be carefully selected medication. 2.[healthfrom.com]
  • Prevention The best way to prevent cardiomyopathy is to prevent the diseases that cause it. Know your risk factors for coronary artery disease. Modify those risks early in life.[drugs.com]
  • Enalapril and carvedilol for preventing chemotherapy-induced left ventricular systolic dysfunction in patients with malignant hemopathies: the OVERCOME trial (preventiOn of left Ventricular dysfunction with Enalapril and caRvedilol in patients submitted[acc.org]
  • To develop a drug that prevents this toxicity, we established a doxorubicin-induced cardiomyopathy model in zebrafish that recapitulates the cardiomyocyte apoptosis and contractility decline observed in patients.[stm.sciencemag.org]

Ask Question

5000 Characters left Format the text using: # Heading, **bold**, _italic_. HTML code is not allowed.
By publishing this question you agree to the TOS and Privacy policy.
• Use a precise title for your question.
• Ask a specific question and provide age, sex, symptoms, type and duration of treatment.
• Respect your own and other people's privacy, never post full names or contact information.
• Inappropriate questions will be deleted.
• In urgent cases contact a physician, visit a hospital or call an emergency service!