We describe a case of ATIN and Fanconi syndrome presenting as hypokalemic paralysis in a patient receiving rifampin. Case presentation A 42-year-old man was hospitalized with sudden-onset weakness in both lower extremities. [bmcnephrol.biomedcentral.com]

Patient 3 A 45-year-old woman, with a remote history of intravenous drug use, presented after 7 days of lethargy and anorexia. [mja.com.au]

At presentation, he had ingested 8 mg of licorice daily for the previous 17 days. The patient presented with severe hypokalemia (1.8 mEq/L) and rhabdomyolysis. His renin activity was 0.44 ng/mL/h, and his aldosterone level was 6.0 pg/mL. [ekjm.org]

Case Presentation A 69-year-old African-American man presented with a 1-month history of progressive generalized weakness, fatigue and anorexia. The patient denied a history of constipation, polyuria or polydipsia, nausea or vomiting. [karger.com]

• Hyperthermia

  Seite 441 - Dantrolene: a review of its pharmacodynamic and pharmacokinetic properties and therapeutic use in malignant hyperthermia, the neuroleptic malignant syndrome and an update of its use in muscle spasticity. ‎ [books.google.de]

  […] reaction associated with hyperthermia and hypercontracted stiff muscles. [hkpp.org]

  Cardiac arrest in special circumstances: Electrolyte abnormalities, poisoning, drowning, accidental hypothermia, hyperthermia, asthma, anaphylaxis, cardiac surgery, trauma, pregnancy, electrocution". [en.wikipedia.org]

  Cardiac arrest in special circumstances: electrolyte abnormalities, poisoning, drowning, accidental hypothermia, hyperthermia, asthma, anaphylaxis, cardiac surgery, trauma, pregnancy, electrocution. Resuscitation. 2010;81(10):1400–1433. 36. [aafp.org]

• Steatorrhea

  Seite 157 - Poley, JR: Role of bile acid malabsorption in pathogenesis of diarrhea and steatorrhea in patients with ileal resection. I. Response to cholestyramine or replacement of dietary long chain triglyceride by medium chain triglyceride. ‎ [books.google.de]

• Muscle Spasticity

  Seite 441 - Dantrolene: a review of its pharmacodynamic and pharmacokinetic properties and therapeutic use in malignant hyperthermia, the neuroleptic malignant syndrome and an update of its use in muscle spasticity. ‎ [books.google.de]

• Paresthesia

  Cardiac arrhythmia Cardiac arrest Ileus Rhabdomyolysis Possibly asymptomatic if hypokalemia is mild Muscle weakness, cramps Paresthesia Abdominal cramps Anorexia Nausea, vomiting Constipation Polyuria, nocturia Excessive thirst Fatigue Palpitations Assessment-Physical [quizlet.com]

  […] combination with an aminoglycoside than as a monotherapy. [5] Other adverse effects include hypersensitivity reactions, hepatotoxicity, neurotoxicity, delirium, bleeding manifestations, electrolyte and acid-base disorders, neutropenia and thrombocytopenia, paresthesia [ijp-online.com]

  HISTORY AND PHYSICAL EXAMINATION Severe hyperkalemia (more than 6.5 mEq per L [6.5 mmol per L]) can cause muscle weakness, ascending paralysis, heart palpitations, and paresthesias. [aafp.org]

• Polyuria

  A vasopressin-resistant polyuria and urinary acidification and concentration defects are the principal renal manifestations. [jamanetwork.com]

  The administration of both has been shown to cause a metabolic alkalosis and hypokalemia with polyuria. [karger.com]

  Potassium may be lost via urine because of: Diuretic drugs like loop diuretics and thiazide diuretics Polyuria (kidney disorder causing excessive urination) A deficiency of magnesium in the blood (a common side effect of alcohol withdrawal) Excessive [curejoy.com]

  Cardiac arrhythmia Cardiac arrest Ileus Rhabdomyolysis Possibly asymptomatic if hypokalemia is mild Muscle weakness, cramps Paresthesia Abdominal cramps Anorexia Nausea, vomiting Constipation Polyuria, nocturia Excessive thirst Fatigue Palpitations Assessment-Physical [quizlet.com]

  Often signs and symptoms of hyperglycemia manifest when serum glucose levels are in the range of 270–360 mg/dl for an extended period and include the classical symptoms of polyphagia, polydipsia, and polyuria ( Table 1 ). [spectrum.diabetesjournals.org]

The workup to elucidate the etiology of his hypercalcemia revealed his intact PTH level to be appropriately suppressed to 0.95 pmol/l (normal range: 1.06-6.9 pmol/l) and his PTH-related peptide level to be 27 ng/l (normal range: 14-27 ng/l). 25-hydroxy [karger.com]

Cardiac evaluations using serial ECGs with measurements of the QTc interval are essential and should be performed on all patients undergoing workup for periodic paralysis. 23, 24, 25 References 1. [hkpp.org]

[…] more practical approach is calculation of the urine potassium-to-creatinine ratio from a spot urine specimen; a ratio greater than 1.5 mEq per mmol (13 mEq per g) is indicative of renal potassium wasting. 18 If no cause is identified with the initial workup [aafp.org]

• Prolonged QT Interval

  Electrocardiogram showed normal sinus rhythm with a heart rate of 88 beats per minute and prolonged QT interval (520 ms) ( Figure 1A ). Corrected QT (QTc) interval was 630 ms. [academic.oup.com]

  SIDE EFFECTS • Prolonged QT interval. • Diarrhoea. • Loss of appetite. • Nausea, Vomiting. • Muscle weakness, stomach cramps. • Retinopathy, accommodation problem, Headache. • Methemoglobinemia. • Haemolysis in G6PD deficiency. 19 20. [slideshare.net]

  Due to prolonged repolarization of ventricular Purkinje fibers, prominent U wave occurs (usually seen at V2 and V3 leads), frequently superimposed upon the T wave and therefore produces the appearance of a prolonged QT interval when serum potassium reduces [en.wikipedia.org]

Thoroughly covers hot topics in this fast-changing field, including ongoing clinical research and changing treatment protocols. [books.google.de]

Therefore, although ECG changes should trigger urgent treatment, treatment decisions should not be based solely on the presence or absence of ECG changes. 32 Peaked T waves are the prototypical, and generally the earliest, ECG sign of hyperkalemia. [aafp.org]

Treatment of hyperkalemia also includes treatment of any underlying causes (for example, kidney disease, adrenal disease, tissue destruction) of hyperkalemia. [medicinenet.com]

Hypertension Initial treatment —In the sixth report of the Joint National Committee on the Detection, Evaluation, and Treatment of High Blood Pressure (JNC VI), a varied selection of antihypertensive agents is recommended for the initial treatment of [drugs.com]

The workup to elucidate the etiology of his hypercalcemia revealed his intact PTH level to be appropriately suppressed to 0.95 pmol/l (normal range: 1.06-6.9 pmol/l) and his PTH-related peptide level to be 27 ng/l (normal range: 14-27 ng/l). 25-hydroxy [karger.com]

[…] as with ongoing diuretic therapy or hyperaldosteronism, 20 mmol per day is usually sufficient. 15 Causes of Hyperkalemia Hyperkalemia is caused by excess potassium intake, impaired potassium excretion, or transcellular shifts ( Table 2 ). 8, 24 The etiology [aafp.org]

Profound potassium depletion may also cause muscle vacuolation and rhabdomyolysis, and renal tubular vacuolation.1 The pathophysiologic events [jamanetwork.com]

Well organized and highly readable, it covers every relevant topic in the field, from anatomy, physiology, and pathophysiology, to diagnosis and management of kidney disease, to fluid and electrolyte disorders, hypertension, dialysis, and renal transplantation [books.google.de]

The results of these studies may have important physiological and pathophysiological implications inasmuch as the results obtained could suggest a mechanistic link between cardiac diseases (substrate), hypokalemia (trigger), and TdP tachyarrhythmias. [circ.ahajournals.org]

The pathophysiology of common causes of syncope. Postgrad Med J. 2000; 76 (902): 750-3 5. Yealy DM, Delbridge TR. Rosen's Emergency Medicine: Concepts and Clinical Practice. 2010; 6. Dubin D. [traumamon.com]

Riccardi D, Brown EM: Physiology and pathophysiology of the calcium-sensing receptor in the kidney. Am J Physiol Renal Physiol 2010;298:F485-F499. [karger.com]

Now in its second edition, this popular and essential comprehensive resource provides a detailed analysis of how to identify, prevent, and manage drug-induced diseases. Edited by James E. Tisdale and Douglas A. [books.google.de]

Prevention and Treatment of Diuretic Induced Hypokalemia The first approach to preventing diuretic-induced hypokalemia is to use the lowest dose possible (Table 1). [barnardhealth.us]

In normal individuals, healthy kidneys can adapt to excessive oral intake of potassium by increasing urine excretion of potassium, thus preventing the development of hyperkalemia. [medicinenet.com]

To prevent cardiac conduction disturbances, intravenous calcium is administered to patients with hyperkalemic electrocardiography changes. [aafp.org]