Patients with these myopathies often present to physicians who do not have the expertise of neuromuscular specialists. [link.springer.com]

Patients typically present with proximal muscle weakness of legs more than arms, with no sensory involvement. [clevelandclinicmeded.com]

An approach to muscle weakness is presented in Figs. 195-1 and 195-2. FIGURE 195-1 Diagnostic evaluation of intermittent weakness. [accessmedicine.mhmedical.com]

Patients with systemic myopathies often present acutely or sub acutely. [en.wikipedia.org]

• Epilepsy

  Metabolic Myopathy Acid maltase or acid alpha-1,4-glucosidase deficiency (Pompe's disease) Glycogen storage disorders 3-11 Carnitine deficiency Fatty acid oxidation defects Carnitine palmitoyl transferase deficiency Mitochondrial Myopathy Myoclonic epilepsy [clevelandclinicmeded.com]

  […] demyelinating polyneuropathy脱髄性多発神経障害 dental health歯科衛生 deoxyglucoseデオキシグルコース deoxyglucosoneデオキシグルコソン dephosphorylation脱リン dephosphorylation脱リン酸化 depolarization脱分極 depolarization-induced calcium release脱分極性カルシウム放出 detachment of retina網膜剥離 developmental delay, epilepsy [jds.or.jp]

• Muscle Spasm

  Episodic muscle spasms, cramps, and weakness. In: Harrison TR, Fauci AS, eds. Harrison’s Principles of internal medicine. 14th ed. New York: McGraw-Hill, 1998:118–22. 3. Pignone MP, Gaynes BN, Rushton JL, Burchell CM, Orleans CT, Mulrow CD, et al. [aafp.org]

• Tremor

  Angioedema (Medical Encyclopedia) Drug allergies (Medical Encyclopedia) Drug-induced diarrhea (Medical Encyclopedia) Drug-induced tremor (Medical Encyclopedia) Taking multiple medicines safely (Medical Encyclopedia) [ Read More ] Muscle Disorders Also [icdlist.com]

  The other reported adverse effects are nausea and vomiting, cholestatic jaundice, agranulocytosis, aplastic and hemolytic anemias, generalized hypersensitivity reactions, neuromuscular and skeletal abnormalities including tremor, myalgia, paresthesia, [jpharmacol.com]

  […] uremia Normal Myopathic MUAPs‡ Atrophy of type II muscle fibers; increased lipofuscin beneath cell membrane; calcium deposits in muscle Thyroid hormone (hyperthyroidism) Proximal, bulbar 40 to 49 years Weight loss; tachycardia; increased perspiration; tremor [aafp.org]

Aspartate aminotransferase levels Other studies may include the following: Electrocardiography Antinuclear antibody levels Genetic testing Electromyography Magnetic resonance imaging (to assess complications or rule out neurologic disease) Muscle biopsy See Workup [emedicine.medscape.com]

A neurologic examination that shows deficits in a single nerve or radicular distribution indicates a possible mononeuritis, entrapment neuropathy, or radiculopathy, and calls for a different workup than that required for a limb paresis in a patient with [aafp.org]

and complete or incomplete resolution after withdrawal of the treatment. [ncbi.nlm.nih.gov]

Treatment is to stop or taper the offending agent, along with supportive measures, such is IV hydration or physical therapy, as needed. [medicalmediareview.com]

No effective treatment is known. [en.wikipedia.org]

However, treatment-refractory myopathies prompts clinicians to use second line agents to achieve remission. [readbyqxmd.com]

In cases suspected to be a primary inflammatory myopathy, specific autoantibodies can be considered to determine the prognosis and rule out associated conditions. [clevelandclinicmeded.com]

Use Additional Use Additional Help Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. [icd10data.com]

It runs through each disease associated with these pathologies, their etiology/pathophysiology, and diagnosis including history, examination and investigation, and the treatment of the diseases where appropriate. [lecturio.com]

These conditions have widely varying etiologies, including congenital or inherited, idiopathic, infectious, metabolic, inflammatory, endocrine, and drug-induced or toxic. [emedicine.medscape.com]

Our long-term goal is to identify clinically significant genetic variants associated with statin myopathy, a complex disorder with diverse etiologies. [grantome.com]

Codes with this note are Etiology codes and must be followed by a Manifestation code or codes. [icd.codes]

[…] collaborate analysis of diabetic criteria in AsiaDECODA研究 Diabetes epidemiology collaborate analysis of diabetic criteria in EuropeDECODE研究 Diabetes epidemiology research internationalDERI研究 Diabetes mellitus due to other specific mechanisms or disease [jds.or.jp]

Epidemiology The incidence of ZDV induced myopathy is not known. However, some studies are available as per literature search. [hiv.imedpub.com]

Table 1 Clinical Features of Common Myopathies Myopathy Epidemiology Distribution of Weakness Other Systemic Manifestations Acquired Myopathies Dermatomyositis Female > male Peak incidence: children and ages 40–60 yr Symmetrical proximal muscle weakness [clevelandclinicmeded.com]

The American College of Cardiology (ACC), American Heart Association (AHA), and National Heart, Lung, and Blood Institute (NHLBI) use myopathy as a general term referring to any disease of the muscles, which is the most common definition. 2 Epidemiology [uspharmacist.com]

Author Affiliations Address reprint requests to the SEARCH Collaborative Group at the Clinical Trial Service Unit and Epidemiological Studies Unit, University of Oxford, Richard Doll Bldg., Old Road Campus, Roosevelt Dr., Oxford OX3 7LF, United Kingdom [nejm.org]

It runs through each disease associated with these pathologies, their etiology/pathophysiology, and diagnosis including history, examination and investigation, and the treatment of the diseases where appropriate. [lecturio.com]

History of drug use is important in the evaluation of patients presenting with various muscle disorders, and an understanding of the pathophysiology of drug-induced myopathy is useful in planning the management of these patients. [medlink.com]

Glucocorticoid-induced myopathy: Pathophysiology, diagnosis, and treatment. Indian J Endocr Metab 2013;17:913-6 How to cite this URL: Gupta A, Gupta Y. Glucocorticoid-induced myopathy: Pathophysiology, diagnosis, and treatment. [ijem.in]

Back to Top Pathophysiology Disruption of the structural integrity and metabolic processes of muscle cells can result from genetic abnormalities, toxins, inflammation, infection, and hormonal and electrolyte imbalances. [clevelandclinicmeded.com]

Statin myopathy: incidence, risk factors and pathophysiology. Curr Atheroscler Rep. 2007;9:389-396. 28. Pasternak RC, Smith SC, Bairey-Merz CN, et al. ACC/AHA/NHLBI clinical advisory on the use and safety of statins. Stroke. 2002;33:2337-2341. 29. [uspharmacist.com]

Now in its second edition, this popular and essential comprehensive resource provides a detailed analysis of how to identify, prevent, and manage drug-induced diseases. Edited by James E. Tisdale and Douglas A. [books.google.de]

Many of these outcomes will be preventable with appropriate identification of genetic risk factors, monitoring of drug dosage, and regular blood testing for indicators of muscle damage. [grantome.com]

[…] can prevent serious complications. [uspharmacist.com]

Since many such side effects are potentially reversible, early recognition is important to prevent residual damage. The clinical spectrum of drug-induced myopathies is very broad, thus a high degree of suspicion should be practised. [oxfordmedicine.com]

[…] severe) decreased/absent reflexes fatigue muscle pain or tenderness muscle weakness normal CK SOB weight loss clinical presentation (more severe) decreased urine output, discolored urine, dyspnea, elevated CPK >400 IU/L dc the agent supportive care prevent [quizlet.com]