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Ductus Arteriosus Aneurysm

Congenital Ductus Arteriosus Aneurysm


Presentation

  • We present the first report of prenatal ultrasonographic diagnosis of isolated ductus arteriosus aneurysm.[ncbi.nlm.nih.gov]
High Fever
  • We present the case of a 6-month-old previously healthy girl who presented with high fever, labored breathing, and an enlarged cardiac silhouette on her chest radiograph.[ncbi.nlm.nih.gov]
  • Abstract We present the case of a 6-month-old previously healthy girl who presented with high fever, labored breathing, and an enlarged cardiac silhouette on her chest radiograph.[pediatrics.aappublications.org]
Hypothermia
  • Through left posterolateral thoracotomy using deep hypothermia with circulatory arrest, proximal descending thoracic aorta including the aneurysm was replaced in 1 case. Their postoperative courses were uneventful.[rwjms1.umdnj.edu]
Stridor
  • At 4 weeks, the infant became asymptomatic, baring occasional stridor, was weaned off from oxygen, started feeding by mouth, and gained weight. At 8 weeks of age, infant became totally free from stridor and a repeat chest X-ray was done (Figure 4 ).[nature.com]
  • Congenital ductus arteriosus aneurysm presenting with stridor in a newborn. J Perinatol. 2002 ; 22 :179–180. doi: 10.1038/sj.jp.7210676. Crossref Medline Google Scholar[circ.ahajournals.org]
  • DAA in newborns is usually asymptomatic, but can present with symptoms of a murmur, cyanosis, stridor, respiratory distress and a weak or feeble cry. On chest x-ray a prominent ductal “bump” can also be seen.[pedecho.org]
Labored Breathing
  • We present the case of a 6-month-old previously healthy girl who presented with high fever, labored breathing, and an enlarged cardiac silhouette on her chest radiograph.[ncbi.nlm.nih.gov]
  • Abstract We present the case of a 6-month-old previously healthy girl who presented with high fever, labored breathing, and an enlarged cardiac silhouette on her chest radiograph.[pediatrics.aappublications.org]
Liver Dysfunction
  • Transient liver dysfunction occurred, however. Symptoms improved dramatically upon removal of the ligature from the umbilical vein.[ncbi.nlm.nih.gov]
Heart Disease
  • We report the case of a 1-year-old child, in whom no previous heart disease was known, who developed a giant aneurysm of the ductus arteriosus during a staphylococcal infection.[ncbi.nlm.nih.gov]
  • Diagnosis and Management of Adult Congenital Heart Disease, by Drs. Gatzoulis, Webb, and Daubeney, is a practical, one-stop resource designed to help you manage the unique challenges of treating long-term adult survivors of congenital heart disease.[books.google.com]
  • ", keywords "congenital heart disease, ductus arteriosus aneurysm, echocardiography, prenatal diagnosis, prenatal ultrasound", author "Puder, {K. S.} and Sherer, {D. M.} and Ross, {R. D.} and Silva, {M. L.} and King, {M. E.} and Treadwell, {M.[experts.umich.edu]
Vascular Disease
  • A small ductus arteriosus is usually well tolerated, but a large ductus arteriosus may lead to congestive heart failure and development of irreversible pulmonary vascular disease 4.[scielo.br]
  • Those with significant left heart volume load can develop congestive heart failure or irreversible pulmonary vascular disease. [ 2 ] Prognosis In most older patients successful closure of the PDA can be achieved without complications, and long-term follow-up[patient.info]
  • Hypertensive pulmonary vascular disease associated with patent ductus arteriosus. Primary or secondary? Circulation 1975 ; 52 : 157-161 [cross-ref] [11] Espino-Vela J., Cardenas N., Cruz R. Patent ductus arteriosus.[em-consulte.com]
  • disease 血管病 vasculature血管構造、脈管系 vasoconstriction血管収縮[性] vasodepressor syncope血管抑制性失神 vasodilatation血管拡張 vasomotor reflex血管運動反射 vasospasm血管攣(れん)縮、血管スパズム vasospastic angina (VSA)血管攣(れん)縮性狭心症 vasovagal reaction血管迷走神経反応 vasovagal syncope血管迷走神経性失神 vegetation[tokyo-med.ac.jp]
  • Differences in clinical presentation between individuals with FTAAD due to TGFBR1 and TGFBR2 have been identified, including an increase in cancer incidence with TGFBR1 compared with TGFBR2 and better survival for women with vascular disease due to TGFBR1[nature.com]
Fetal Disorder
  • Ductus arteriosus aneurysm is a rare fetal disorder. A 35-year-old primigravida had an uneventful antenatal course. Ultrasound examination at 30 weeks of gestation revealed hydramnios.[ncbi.nlm.nih.gov]
Encephalopathy
  • Umbilical arterial and venous blood gas values showed marked acidosis (pH 6.81 and 6.88, respectively) without signs of encephalopathy. General and cardiovascular examinations were normal.[circ.ahajournals.org]
Agitation
  • CASE PRESENTATION A 2-day-old full-term infant was found to have a weak cry and intermittent stridor, more so while agitated, both during inspiration and expiration.[nature.com]

Workup

  • The differential diagnosis of this mediastinal mass, complications related to ductus aneurysms and the appropriate radiographic workup are discussed.[ncbi.nlm.nih.gov]
  • […] vena cava for nutcracker syndrome Hybrid treatment of an ascending aortic pseudoaneurysm following multiple sternotomies Wakeup test decrease shunts insertion during carotid endarterectomy under general anesthesia Accuracy of FDGPETCT in the diagnostic workup[books.google.com]
  • On initial complementary workup the ECG revealed atrial fibrillation and voltage criteria of LVH, and the echocardiogram disclosed LVH, non-dilated LV with preserved systolic function, mild aortic regurgitation (tricuspid aortic valve) and normal right-side[elsevier.pt]
  • Thrombophilia workup was not done as she was already receiving heparin through the umbilical arterial line.[jcnonweb.com]
Staphylococcus Aureus
  • Comprehensive evaluation discovered a ductus arteriosus aneurysm and pericardial effusion with methicillin-resistant Staphylococcus aureus bacteremia.[ncbi.nlm.nih.gov]
  • The patient had an infectious complication of the operative wound, in which Staphylococcus aureus was identified.[scielo.br]

Treatment

  • In the past, open surgery was the only available option for treatment. Nowadays, endovascular repair has emerged as a safe and less invasive treatment option for aortic aneurysms.[ncbi.nlm.nih.gov]

Prognosis

  • Diagnosis Pseudoaneurysm (forms acute angle with aorta) On aortography, will demonstrate an intimal flap and/or Delayed clearance of contrast Penetrating ulcer Aortic dissection Treatment Usually unnecessary unless diverticulum is greater than 3 cm Prognosis[learningradiology.com]
  • Abstract Arterial pseudo-aneurysms complicating pancreaticoduodenectomy are rare but have a poor prognosis. They usually result from arterial erosion due to pancreatic fistula.[ncbi.nlm.nih.gov]
  • Those with significant left heart volume load can develop congestive heart failure or irreversible pulmonary vascular disease. [ 2 ] Prognosis In most older patients successful closure of the PDA can be achieved without complications, and long-term follow-up[patient.info]
  • Furthermore, an atrial septal aneurysm can be confused with other congenital anomalies e.g. cor triatriatum, in which management and prognosis are quite different.[cardiovascularultrasound.biomedcentral.com]
  • […] embolic stroke, hemodynamic instability due to rupture Demographics Age All age groups More common in children than adults Gender Equally seen in males and females No sex preponderance Epidemiology 9-26% of all adults 33% of infants Natural History & Prognosis[sites.google.com]

Etiology

  • The role of DAA was suspected as a potential etiology of systemic thromboembolism in this case. CT angiography with three-dimensional reconstruction was valuable delineating the adjunctive vascular structures.[ncbi.nlm.nih.gov]
  • Additional suggested etiologies include: Connective tissue disorders ( Marfan's, Ehlers- Danlos and Larsen syndrome) Infection (1 ,5 ).[fetalultrasound.com]
  • Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology.[icd10coded.com]
  • […] bypass fetus' fluid-filled lungs Ductus arteriosus normally closes after birth Ductus diverticulum is remnant of infundibular part of ductus arteriosus Located at transition from transverse aorta to fixed descending aorta Genetics: No known genetic etiology[sites.google.com]
  • The etiology is unknown, but the syndrome is considered a probable connective tissue disorder and the cardiovascular manifestations are similar to those of Marfan syndrome.[rwjms1.umdnj.edu]

Epidemiology

  • […] signs/symptoms: Aneurysmal dilatation may present with chest pain, embolic stroke, hemodynamic instability due to rupture Demographics Age All age groups More common in children than adults Gender Equally seen in males and females No sex preponderance Epidemiology[sites.google.com]
  • […] remains open beyond three months of life in preterm infants and beyond one year of life in full-term infants it is termed as persistent patency of ductus arteriosus because the incidence of spontaneous closure beyond these time limits is very low. [ 1 ] Epidemiology[patient.info]
  • Recent epidemiological studies have shown a possible association between surgical PDA ligation and impaired neurological development, retinopathy and chronic lung disease [ 49, 50, 51, 52, 53, 54, 55, 56 ].[em-consulte.com]
Sex distribution
Age distribution

Pathophysiology

  • The pathophysiology and literature are reviewed.[ncbi.nlm.nih.gov]
  • Ascending aortic dilatation associated with bicuspid aortic valve: pathophysiology, molecular biology, and clinical implications. Circulation 2009; 119 : 880–890. 17. Janssens K, Vanhoenacker F, Bonduelle M, et al.[nature.com]
  • In the case of PDA-related Eisenmenger's pathophysiology, PDA closure must be avoided. In these cases, the ductus may also play an important palliative role [ 3 ].[em-consulte.com]

Prevention

  • Functional outcome of hypogastric revascularisation for prevention of buttock claudication in patients with peripheral artery occlusive disease Endovascular treatment of traumatic thoracic aortic injuries short and mediumterm Followup The management of[books.google.com]
  • Prevention The disease is genetic and there is a probability of it occurring during pregnancy. To prevent the disease, one can follow the basics steps in order to have a completely healthy pregnancy: Taking a healthy diet. Regular physical workout.[medanta.org]
  • Conclusion: Aneurysm of the ductus arteriosus is a rare entity found in adults, however, the recognition and ability to differentiate this from a traumatic aortic injury is crucial in order to prevent unnecessary surgical intervention.[scmr.org]
  • Children’s heart conditions can’t be prevented, but a lot can be done to improve and often completely repair their hearts at any age.[nemours.org]
  • Is the prevention of infective endarteritis a valid reason for closure of the patent arterial duct? Eur Heart J 1997; 18: 364-6. [ Links ] 8. Rangel-Abundis A, Baduí E, Verdin R, et al.[scielo.br]

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