Abdominal pain, diarrhea, GI bleeding, hepatosplenomegaly and small bowel obstruction are well described presentations. Still gastrointestinal histoplasmosis often results in either vague symptomatology or no symptoms. [uthsc.pure.elsevier.com]

Dilated stomach with delayed emptying and deformed cap was present in 3 cases. In 2 cases filling defect in the antral region was present. [jemds.com]

However, in the present case, no clinical features of immunodeficiency were observed and HIV status being negative. The present case presented with gastric outlet obstruction which clinically and endoscopically mimicked gastric carcinoma. [jmedscindmc.com]

The present case reinforces the requirement for the early recognition and correct treatment of peptic ulcers accompanied with multiple complications. A 67-year-old man presented with recurrent abdominal pain, fever and melena. [spandidos-publications.com]

Gastrointestinal tuberculosis presenting as isolated involvement of the duodenum is a rare case. Case Presentation: A 13 year male, presented with features of gastric outlet obstruction. [casereports.bmj.com]

• Weight Loss

  But the most common cause is significant weight loss leading to loss of mesenteric fat pad in patients with severe debilitating illnesses like malignancy, malabsorption syndromes, burns etc. 3 In postoperative period, it has been seen following gastric [ispub.com]

  Loss of appetite with persistent bloating or fullness after eating also suggests gastric outlet obstruction. Prolonged vomiting may cause weight loss, dehydration, and alkalosis. [merckmanuals.com]

  Blind loop syndrome (sometimes called stasis syndrome or stagnant loop syndrome) - this affects digestion and absorption, causing: Bloating, loss of appetite, abdominal pain and nausea. Fatty stools (steatorrhoea). Diarrhoea with weight loss. [patient.info]

  Early satiety, unexplained weight loss, loss of appetite, progressive dysphagia, gradually worsening symptoms of gastric outlet obstruction Gastric cancer is another complication in gastric ulcer disease. [medicaljoyworks.com]

  Moderate weight loss that may not raise any concern. Late Symptoms As the condition worsens, then additional symptoms may be noticed in addition to the early symptoms. Projectile vomiting. Severe weight loss. Dehydration due to excessive vomiting. [healthhype.com]

• Vomiting

  She showed significant clinical improvement with resolution of vomiting and weight gain. [jdeonline.in]

  Vomiting- The symptoms of peptic ulcers may include vomiting. Vomiting after consumption of food may be caused by an ulcer, food poisoning, or gastritis (inflammation of the stomach lining). [alaskagi.com]

  Vomiting is intermittent, non bilious and occurs one hour after meals containing undigested foods. [medicaljoyworks.com]

  Clinical Sign and Symptoms Nausea and vomiting are the cardinal symptoms of GOO. Vomiting usually is described as nonbilious, and it characteristically contains undigested food particles. [laparoscopyhospital.com]

  Nausea and Vomiting Obstruction of the duodenum can also cause patients to become nauseated and vomit. [livestrong.com]

• Nausea

  Nausea- The symptoms of peptic ulcers may include nausea. Nausea is a feeling of sickness with an inclination to vomit. Nausea has many possible causes. [alaskagi.com]

  Nausea and Vomiting Obstruction of the duodenum can also cause patients to become nauseated and vomit. [livestrong.com]

  […] vomiting heartburn moody pms or vomiting heartburn moody pms or two and have had the following symptoms: nausea vomiting heartburn Make These 8 Simple Changes for a Healthy Fall Taking any of these may sound utterly strange at first but I was getting [transnationalterrorism.eu]

  Some people may experience nausea, vomiting, constipation, diarrhea, and headaches after taking these. Other side effects may include bruising or bleeding. [medicalnewstoday.com]

  The side effects of these antibiotic are usually mild and include: nausea, vomiting, diarrhoea, and a metallic taste in the mouth. [hse.ie]

• Abdominal Pain

  Abdominal pain, diarrhea, GI bleeding, hepatosplenomegaly and small bowel obstruction are well described presentations. Still gastrointestinal histoplasmosis often results in either vague symptomatology or no symptoms. [uthsc.pure.elsevier.com]

  Following anti-hemorrhagic and antibiotic treatments, the symptoms of fever and abdominal pain were relieved. [spandidos-publications.com]

  Symptoms of Peptic Ulcer Disesase Symptoms include: Upper abdominal pain Pain on hunger Pain at night Pain relieved by food Nausea, loss of appetite, fullness after eating can occur. [singhealth.com.sg]

  In patients in whom abdominal pain is the major clinical symptom, difficulties related to the characterization of pain and to the high prevalence of functional abdominal pain may delay the diagnosis. [scielo.br]

  Gastric ulcers cause abdominal pain which aggravate with meals. So this goes as a cycle leading to increase morbidity. [medicaljoyworks.com]

• Epigastric Pain

  […] develops 1-3h after meal hunger pain and central back pain pain is relieved by eating or anatacids nausea and epigastric pain (gnawing burning sensation) periods of pain over weeks and then periods of remission treatment of duodenal ulcer medical surgical [quizlet.com]

  Burning epigastric pain or epigastric cramps between meals, that wake the patient at night. Recurrent episodes characteristically last a few days and are often accompanied by nausea and even vomiting. [medicalguidelines.msf.org]

  CASE REPORT A 31 year old male was admitted to our institution with a 1 year history of recurrent epigastric pain and an acute episode of vomiting. Epigastric pain was characterized as intermittent, mild and gnawing in character. [wjgnet.com]

  Other factors responsible for disease includes eating too much spicy and fatty food, stress, drinking alcohol and coffee.2 Symptoms of peptic ulcer include epigastric pain, heartburn, nocturnal pain, nausea, postprandial pain, weight loss due to decreased [medcraveonline.com]

  Case Reports Case 1 A 50-year-old female presented with history of epigastric pain, recurrent vomiting and significant weight loss since 4 months. [jdeonline.in]

• Recurrent Vomiting

  Case Reports Case 1 A 50-year-old female presented with history of epigastric pain, recurrent vomiting and significant weight loss since 4 months. [jdeonline.in]

  Individuals with gastric outlet obstruction will often have recurrent vomiting of food that has accumulated in the stomach, but which cannot pass into the small intestine due to the obstruction. [en.wikipedia.org]

  Recurrent vomiting, bloating sensation after meal, early satiety, weight loss Gastric outlet obstruction following gastric ulcer( due to fibrosis during healing) may present with those symptoms. [medicaljoyworks.com]

  vomiting, or a family history of GI cancer. [clinicaladvisor.com]

  Recent sustained weight loss, progressive dysphagia or odynophagia, recurrent vomiting – with or without pain – should raise the suspicion of an outlet obstruction from a duodenal ulcer. [cancertherapyadvisor.com]

You might have to undergo a more extensive medical workup looking for unusual underlying causes for peptic ulcer disease. [verywell.com]

WORKUP Laboratory Studies • Obtain a CBC. Check the hemoglobin and hematocrit to. rule out the possibility of anemia. • Obtain an electrolyte panel. [slideshare.net]

As part of the initial workup, exclude the possibility of functional nonmechanical causes of obstruction, such as diabetic gastroparesis. [emedicine.medscape.com]

Possible treatments for this disease include conservative treatment with drugs, endoscopic sphincterotomy and surgical therapy. The choice is based on the etiology, the severity of the disease and the patient's general condition. [spandidos-publications.com]

Surgical treatment The choice of surgical treatment depends on the size and localization of the perforation, the viability of the duodenal walls, the degree of local contamination and underlying etiology. [tandfonline.com]

In severe or recurrent cases, dose can be increased to 40 mg once daily and the treatment can be prolonged for up to 8 weeks. – If the patient has frequent recurrences, unrelated to NSAID use, that require repeated treatment with antiulcer drugs: see [medicalguidelines.msf.org]

Surgical Treatment Surgical treatment does not eliminate the risk of ulcer recurrence and is associated with late complications. [empendium.com]

Prognosis A functioning and unrestricted intestine is a prerequisite for living independent of the most advanced and continuous medical care available. Achieving this desirable goal is the rule with surgery for duodenal obstructions of all types. [medical-dictionary.thefreedictionary.com]

Prognosis Over the past 3 decades, the prognosis of patients with gastric perforation has improved. But delays in diagnosis and treatment can lead to death. [ncbi.nlm.nih.gov]

Prognosis Prognosis will depend on the type and extent of the obstruction, the infant's age at diagnosis, the infant's overall condition, and the presence and severity of any other congenital anomalies. [encyclopedia.com]

In the rare cases when surgery cannot be done, prognosis is poor. Obstruction may be caused by scarring, spasm, or inflammation from an ulcer. [merckmanuals.com]

The choice is based on the etiology, the severity of the disease and the patient's general condition. [spandidos-publications.com]

Etiology Risk factors Chronic gastritis caused by H. pylori, a curved, flagellated gram-negative rod Duodenal ulcers : up to 90% are due to H. pylori infection Gastric ulcers : up to 80% are due to H. pylori infection Chronic gastritis of other etiology [amboss.com]

Pathology Etiology Gastric outlet obstruction can be due to malignant or benign causes. [radiopaedia.org]

The incidence of GOO in patients with peripancreatic malignancy, the most common malignant etiology, has been reported between 15- 20%. [tropicalgastro.com]

Etiology of PUD However, we must remember that approximately 5-15% of patients considered Hp negative, despite performing wide comprehensive etiological studies, do not get to find again the precise cause of PU, which are referred to as "idiopathic”. [elynsgroup.com]

Reference article This is a summary article; read more in our article on peptic ulcer disease. anatomy stomach epidemiology older population with M:F ratio of 3:1 main risk factors H. pylori NSAID and corticosteroid use severe physical stress presentation [radiopaedia.org]

To critically review the evidence on epidemiology, diagnostic management, and available treatments for PUD in the pediatric age. Methods. [hindawi.com]

(An excellent review of the epidemiology of GBS disease prior to the publication of prevention guidelines for neonatal GBS disease) Schuchat, A. “Epidemiology of group B streptococcal disease in the United States: shifting paradigms”. [infectiousdiseaseadvisor.com]

Capsular polysaccharide typing is significant and essential for epidemiological studies of GBS. [archcid.com]

Approaches each topic using the same easy-to-follow format : disease presentation, pathophysiology, and diagnostics, followed by surgical therapy. Discusses which approach to take, how to avoid or minimize complications, and what outcomes to expect. [books.google.com]

[…] main risk factors H. pylori NSAID and corticosteroid use severe physical stress presentation dyspeptic symptoms haemorrhage (14%) incidental (faecal-occult blood) acute (melaena, haematemesis, or both) perforation (6%) gastric-outlet obstruction (rare) pathophysiology [radiopaedia.org]

Delayed gastric emptying, increased intragastric pH, and reflux of the duodenal contents into the stomach are factors indicative of the pathophysiology of gastric candidiasis after gastric surgery. [dbpia.co.kr]

Malignant Tumours of the stomach, including adenocarcinoma (and its linitis plastica variant), lymphoma, and gastrointestinal stromal tumours Pathophysiology[edit] In a peptic ulcer it is believed to be a result of edema and scarring of the ulcer, followed [en.wikipedia.org]

[…] ulcer bleeding secondary to NSAID use; however, no clinical data is available that proves that this strategy prevents ulcer complication No study has evaluated the efficacy of H2RAs in chronic NSAID users Less effective than proton pump inhibitors (PPIs [specialty.mims.com]

The use of intrapartum antibiotics for selective high-risk patients, while being sufficient for the prevention of early onset GBS disease, has been found to be insufficient for prevention of late onset GBS disease. [hindawi.com]

The data will be important in the detection, prevention, treatment and vaccination against this microorganism. Project Code PI13/00127 [isglobal.org]

Oversew the area with a continuous suture to prevent a postoperative leak. No drainage procedure is required. E. Complications 1. [laparoscopyhospital.com]

Treatment of the esophagus, stomach or duodenal ulcersaims to relieve pain, heal the ulcer, and prevent complications. [medicinenet.com]