Presentation
Mild cases are simply a redness of the lining of the stomach and duodenum, while severe cases may present as erosions with bleeding and ulceration. [nobelmedicalgroup.com]
The epithelial cells may present various stages of degeneration. The serosa is usually only slightly [jamanetwork.com]
More pronounced neutrophilic inflammation, including cryptitis and crypt abscesses, can also be present. [archivesofpathology.org]
Treatment at present is similar to that of peptic ulcer, with the withdrawal of any predisposing and precipitating factors such as aspirin, alcohol and smoking. Antacids may relieve the symptoms. [ncbi.nlm.nih.gov]
In control specimens, neutrophil polymorphs were very infrequent but a substantial neutrophil polymorph infiltration of the epithelium and lamina propria was present in both types of duodenitis. [jcp.bmj.com]
Gastrointestinal
- Abdominal Pain
Henoch-Schonlein purpura: an atypical cause of abdominal pain in a 70-year-old man: case report. [gastrojournal.org]
She suffered from intractable abdominal pain and elected to undergo palliative celiac plexus neurolysis. [ncbi.nlm.nih.gov]
pain, hematemesis In advanced cases: symptoms related to gastric outlet obstruction or acute abdominal pain (clinical features of peritonitis) secondary to duodenal perforation Laboratory Negative celiac sprue serology (antitissue transglutaminase, endomysial [pathologyoutlines.com]
Inflammation in the lining of the duodenum may result in abdominal pain, bleeding, and other gastrointestinal symptoms. [hellodoktor.com]
- Dyspepsia
We detected ulcer-like dyspepsia in 87 patients (66.4%) and dysmotility-like dyspepsia in 44 patients (33.6%). There were no marked differences in biochemical parameters between the groups. [go.gale.com]
It is not yet known what effect these measures may have on the duodenitis as opposed to the symptoms of dyspepsia. [ncbi.nlm.nih.gov]
Dyspepsia management guidelines. Links: duodenal ulcer [gpnotebook.co.uk]
- Regurgitation
1996 Abstracts The American Pediatric Society and The Society for Pediatric Research Published: 01 April 1996 Pediatric Research volume 39, page121(1996)Cite this article 546 Accesses 0 Altmetric Metrics details Regurgitation/vomiting (R/V) in infants [nature.com]
Workup
The patient underwent an upper endoscopy and a colonoscopy for further diagnostic workup. The upper endoscopy was significant for diffuse mucosal edema, hemorrhage and ulceration starting from the postbulbar duodenum (Figure A, B, C). [gastrojournal.org]
Treatment
Avoiding alcohol Stopping smoking Your healthcare provider can tell you more about what treatments are needed. Recovery and follow-up With treatment, most cases of duodenitis clear up completely. [saintlukeskc.org]
Treatment for duodenitis depends on the cause. [webmd.com]
They can help determine the cause and get you the treatment you need. [healthline.com]
Treatment for both gastritis and duodenitis varies from person to person. The success of each treatment and the recovery time will depend on the underlying cause and whether or not the individual can follow their treatment plan. [medicalnewstoday.com]
Prognosis
LM neutrophils - "found without searching", eosinophils - "found without searching", plasma cells (increased), intraepithelial lymphocytes Site duodenum Associated Dx Helicobacter gastritis Prevalence uncommon Endoscopy erythema Prognosis benign Treatment [librepathology.org]
[…] obstruction or acute abdominal pain (clinical features of peritonitis) secondary to duodenal perforation Laboratory Negative celiac sprue serology (antitissue transglutaminase, endomysial antibodies, deamidated gliadin peptide) Prognostic factors Good prognosis [pathologyoutlines.com]
Etiology
Etiology of duodenitis was correlated with the patient's clinical diagnosis. [ncbi.nlm.nih.gov]
Introduction Ulcerative colitis (UC) is a chronic inflammatory disease of the colon that has an unknown etiology. [hindawi.com]
Pathology Etiology A duodenitis can result from both intrinsic processes within the duodenum as well as from processes occuring outside the duodendum. It can occur from infective as well as non-infective inflammatory processes. [radiopaedia.org]
Epidemiology
Inflammatory Bowel Disease Knowledge Centre The Inflammatory Bowel Disease (IBD) Knowledge Centre contains key information relating to the epidemiology and pathophysiology of Crohn’s disease and ulcerative colitis, highlighting prevalence, impact and [epgonline.org]
Malaty HM: Epidemiology of Helicobacter pylori infection. Best Pract Res Clin Gastroenterol 2007; 21: 205-201 12. [arastirmax.com]
Epidemiological data are poor and, in most cases, all gastroenteritis are displayed together. Thereby, the relevance of works outlining the parasitic duodenitis profile is clear. [scielo.br]
Epidemiologic associations - Helicobacter infections are associated with:[1] Gastritis. Peptic ulcers. Cancer. Carcinoma. MALT lymphoma. [librepathology.org]
Binding of deamidated gluten to human leukocyte antigen (HLA) on antigen-presenting cells in the duodenal lamina propria triggers a gliadin-specific, CD4+ T-lymphocyte–mediated immune response.11 Genetic predisposition is an important determinant of the epidemiology [archivesofpathology.org]
Pathophysiology
Inflammatory Bowel Disease Knowledge Centre The Inflammatory Bowel Disease (IBD) Knowledge Centre contains key information relating to the epidemiology and pathophysiology of Crohn’s disease and ulcerative colitis, highlighting prevalence, impact and [epgonline.org]
These findings suggest that duodenitis can cause symptoms and may be a part of the pathophysiological spectrum of duodenal ulceration rather than a separate disease. It may represent both the production and healing phases of duodenal ulceration. [thelancet.com]
With the data at present available, it appears that duodenitis is part of the pathophysiological spectrum of the duodenal ulcer diathesis rather than a separate disease. It may represent both the production and healing phases of duodenal ulceration. [ncbi.nlm.nih.gov]
[…] gastric foveolar metaplasia and Brunner gland hyperplasia Usually mild and regresses with treatment Terminology Also termed chronic nonspecific duodenitis ICD coding ICD-10: K29.80 - duodenitis without bleeding Sites Duodenum, usually proximal segment Pathophysiology [pathologyoutlines.com]
Conclusions Secondary duodenal mucosal lesions with different pathophysiology, such as IBD or CMV infection, are rare. Disease extent and age seems the most distinctive feature of secondary duodenal mucosal lesions. [kjim.org]
Prevention
Early diagnosis and treatment can stop duodenitis from worsening and prevent another medical emergency, so talk to your doctor as soon as possible to prevent this serious condition. [hellodoktor.com]
Prevention of the disease should include the mandatory transition to a healthy and balanced diet, active sports, and compliance with personal hygiene (to avoid infection with helminths, pathogens). [doctorpro.ua]
‘A 67-year-old woman was prescribed ticlopidine for the primary prevention of heart disease after endoscopy revealed severe erosive gastritis and duodenitis caused by aspirin therapy.’ [lexico.com]
It should also be noted that this bacteria could be transferred from person to person, so an utmost care is required to prevent its spread. [torrancegastro.com]
Duodenitis prevention If you want to avoid duodenitis, then you have to focus on controlling excess acid in your stomach. This could mean cutting down on certain foods or changing some lifestyle habits. [belmarrahealth.com]