CONCLUSION: Though similar in clinical presentation, POTS and OI are different entities with greater, albeit still mild, dysautonomia in POTS. [ncbi.nlm.nih.gov]

• Infectious Mononucleosis

  However, majority of these cases have a preceding viral infection such as herpes simplex, infectious mononucleosis, rubella or coxsackie B. A unique patient in whom acute dysautonomia followed mumps is reported. [ncbi.nlm.nih.gov]

• Abdominal Cramps

  Patients may complain of abdominal cramps, or of unusual or foul-smelling stools. This is likely due to an increased production of butyrate by gut bacteria. [doi.org]

• Foul-Smelling Stools

  Patients may complain of abdominal cramps, or of unusual or foul-smelling stools. This is likely due to an increased production of butyrate by gut bacteria. [doi.org]

• Orthostatic Hypotension

  N Engl J Med 1993; 329:1449–55 Robertson D: The pathophysiology and diagnosis of orthostatic hypotension. [doi.org]

  The chief dysautonomic symptoms and signs included constipation, urinary dysfunction, anhydrosis, ptosis, and orthostatic hypotension. Neurophysiologic studies revealed no involvement of the somatic nervous system. [ncbi.nlm.nih.gov]

  Measures to combat orthostatic hypotension include elevation of the head of the bed, water bolus (rapid infusion of water given intravenously), a high-salt diet, and drugs such as fludrocortisone and midodrine. [ninds.nih.gov]

• Cerebellar Sign

  Main symptoms are cerebellar signs, ophthalmoplegia, gait disturbance. In SCA -1, -2, -3, -4, -6, -14, -18, -25, -27 types senso-motor axonal neuropathia can occur due to the lesion of thick myelinated nerve fibers. [tankonyvtar.hu]

• Opisthotonus

  Here we report a case of hanging associated anoxic brain injury resulting in severe dysautonomia and an extreme opisthotonus (arc de cercle). [ncbi.nlm.nih.gov]

See the first two references for additional systemic implications, complications, workup information, and management advice. [dermatologyadvisor.com]

A complete workup for erectile dysfunction in men should include history (medical and sexual); psychological evaluation; hormone levels; measurement of nocturnal penile tumescence; tests to assess penile, pelvic, and spinal nerve function; cardiovascular [care.diabetesjournals.org]

• Hypocapnia

  Circulation 1954; 10:362–5 Burnum JF, Hickam JB, McIntosh H: The effect of hypocapnia on arterial blood pressure. [doi.org]

• Cardiac Output Decreased

  In phase II, as continued strained expiration is maintained, venous return is reduced and cardiac output decreases. This produces a decrease in blood pressure with reflex tachycardia. [doi.org]

Is there any treatment? There is usually no cure for dysautonomia. Secondary forms may improve with treatment of the underlying disease. In many cases treatment of primary dysautonomia is symptomatic and supportive. [web.archive.org]

On the other hand, by understanding the pathophysiology, treatment success is possible by directing therapies toward the root causes and just as importantly, enlisting the patient in a daily treatment plan. [ncbi.nlm.nih.gov]

What is the prognosis? The outlook for individuals with dysautonomia depends on the particular diagnostic category. [web.archive.org]

Prognosis The outlook for individuals with dysautonomia depends on the particular diagnostic category. [ninds.nih.gov]

What is the prognosis for dysautonomia? The outlook for individuals with dysautonomia depends on the particular diagnostic category. [my.clevelandclinic.org]

Its etiology is as yet unknown. However, majority of these cases have a preceding viral infection such as herpes simplex, infectious mononucleosis, rubella or coxsackie B. A unique patient in whom acute dysautonomia followed mumps is reported. [ncbi.nlm.nih.gov]

"It is not clear if patients with postural tachycardia syndrome (POTS) and Ehlers-Danlos syndrome (hEDS) differ from patients with POTS due to other etiologies. [dinet.org]

Etiology FD is an autosomal recessive disorder characterized by autonomic and sensory dysfunction. It is classified as a hereditary sensory and autonomic neuropathy (HSAN type III) disorder. Pathophysiology This is a genetic disease (as above). [dermatologyadvisor.com]

[…] involvement occurs but is very rare Mixed sensorimotor neuropathy (subacute/chronic) • • • • • • • Very large differential diagnosis Most sensorimotor neuropathies occur over a subacute to chronic (weeks/ months) time course May divide differential by etiology [123doc.org]

Long-term follow-up studies are needed to distinguish the exact roles of cardiovascular risk factors, nephropathy, and CAN in the etiology of cardiovascular disease. [care.diabetesjournals.org]

Epidemiology In general, these can occur in men and women at any age, but the epidemiology will depend on the particular cause. Some causes are very rare. [patient.info]

Epidemiology[edit] Familial dysautonomia is seen almost exclusively in Ashkenazi Jews and is inherited in an autosomal recessive fashion. Both parents must be carriers in order for a child to be affected. [en.wikipedia.org]

Discusses the epidemiology over a 5-year period in Israel. The incidence of FD in Ashkenazi Jews was found to be 1:3703 [years 1977-1981]; the carrier incidence was found to be 1:32.) Copyright 2017, 2012 Decision Support in Medicine, LLC. [dermatologyadvisor.com]

EPIDEMIOLOGY OF DAN The reported prevalence of DAN varies, depending on whether studies have been carried out in the community, clinic, or tertiary referral center. [care.diabetesjournals.org]

On the other hand, by understanding the pathophysiology, treatment success is possible by directing therapies toward the root causes and just as importantly, enlisting the patient in a daily treatment plan. [ncbi.nlm.nih.gov]

“A critical review of the pathophysiology of dysautonomia following traumatic brain injury”. Neurocrit Care 8 (2): 293–300. doi:10.1007/s12028-007-9021-3. PMID 17968518. J Pediatr. 1999 Oct;135(4):494-9. [internationalpain.org]

Keywords : fibromyalgia; autonomic nervous system; pathophysiology; rheumatic disease; adrenergic receptor; dystautonomia. [scielo.br]

N Engl J Med 1993; 329:1449–55 Robertson D: The pathophysiology and diagnosis of orthostatic hypotension. [doi.org]

Early management can help prevent comorbidities including secondary brain injury while also improving patient outcomes. [ncbi.nlm.nih.gov]

This research aims to discover ways to diagnose, treat, and, ultimately, prevent these disorders. [web.archive.org]

For example, a feeding tube inserted into the stomach can assist in feeding, and prevent fluids etc. from entering the lungs, while drugs are prescribed to prevent vomiting and seizures, eye drops lubricate dry eyes, and surgery can correct scoliosis. [brainfoundation.org.au]