CONCLUSION: Though similar in clinical presentation, POTS and OI are different entities with greater, albeit still mild, dysautonomia in POTS. [ncbi.nlm.nih.gov]

Excessive sympathetic activity can present as hypertension or a rapid pulse rate. Treatment There is usually no cure for dysautonomia. Secondary forms may improve with treatment of the underlying disease. [ninds.nih.gov]

• Foul-Smelling Stools

  Patients may complain of abdominal cramps, or of unusual or foul-smelling stools. This is likely due to an increased production of butyrate by gut bacteria. [doi.org]

• Orthostatic Hypotension

  Hallmarks of generalized dysautonomia due to sympathetic failure are impotence (in men) and a fall in blood pressure during standing (orthostatic hypotension). [ninds.nih.gov]

  N Engl J Med 1993; 329:1449–55 Robertson D: The pathophysiology and diagnosis of orthostatic hypotension. [doi.org]

  orthostatic hypotension, orthostatic hypertension, autonomic instability, and a number of lesser-known disorders such as cerebral salt-wasting syndrome. [internationalpain.org]

  The chief dysautonomic symptoms and signs included constipation, urinary dysfunction, anhydrosis, ptosis, and orthostatic hypotension. Neurophysiologic studies revealed no involvement of the somatic nervous system. [ncbi.nlm.nih.gov]

• Cerebellar Sign

  Clinical signs are due to the degeneration of cerebellum and brain stem. Main symptoms are cerebellar signs, ophthalmoplegia, gait disturbance. [tankonyvtar.hu]

See the first two references for additional systemic implications, complications, workup information, and management advice. [dermatologyadvisor.com]

A complete workup for erectile dysfunction in men should include history (medical and sexual); psychological evaluation; hormone levels; measurement of nocturnal penile tumescence; tests to assess penile, pelvic, and spinal nerve function; cardiovascular [care.diabetesjournals.org]

Is there any treatment? There is usually no cure for dysautonomia. Secondary forms may improve with treatment of the underlying disease. In many cases treatment of primary dysautonomia is symptomatic and supportive. [web.archive.org]

Treatment There is usually no cure for dysautonomia. Secondary forms may improve with treatment of the underlying disease. In many cases treatment of primary dysautonomia is symptomatic and supportive. [ninds.nih.gov]

On the other hand, by understanding the pathophysiology, treatment success is possible by directing therapies toward the root causes and just as importantly, enlisting the patient in a daily treatment plan. [ncbi.nlm.nih.gov]

If one or more of these conditions is identified, other treatments may be recommended. [centerformultisystemdisease.com]

As a result, there is no cure and no treatment. This is because of its slow progression. Treatment can, however, manage specific symptoms through lifestyle changes and medications. [medicalnewstoday.com]

Prognosis The outlook for individuals with dysautonomia depends on the particular diagnostic category. [ninds.nih.gov]

What is the prognosis? The outlook for individuals with dysautonomia depends on the particular diagnostic category. [web.archive.org]

What is the prognosis for dysautonomia? The outlook for individuals with dysautonomia depends on the particular diagnostic category. [my.clevelandclinic.org]

Its etiology is as yet unknown. However, majority of these cases have a preceding viral infection such as herpes simplex, infectious mononucleosis, rubella or coxsackie B. A unique patient in whom acute dysautonomia followed mumps is reported. [ncbi.nlm.nih.gov]

"It is not clear if patients with postural tachycardia syndrome (POTS) and Ehlers-Danlos syndrome (hEDS) differ from patients with POTS due to other etiologies. [dinet.org]

[…] involvement occurs but is very rare Mixed sensorimotor neuropathy (subacute/chronic) • • • • • • • Very large differential diagnosis Most sensorimotor neuropathies occur over a subacute to chronic (weeks/ months) time course May divide differential by etiology [123doc.org]

Etiology FD is an autosomal recessive disorder characterized by autonomic and sensory dysfunction. It is classified as a hereditary sensory and autonomic neuropathy (HSAN type III) disorder. Pathophysiology This is a genetic disease (as above). [dermatologyadvisor.com]

Long-term follow-up studies are needed to distinguish the exact roles of cardiovascular risk factors, nephropathy, and CAN in the etiology of cardiovascular disease. [care.diabetesjournals.org]

Epidemiology In general, these can occur in men and women at any age, but the epidemiology will depend on the particular cause. Some causes are very rare. [patient.info]

Epidemiology[edit] Familial dysautonomia is seen almost exclusively in Ashkenazi Jews and is inherited in an autosomal recessive fashion. Both parents must be carriers in order for a child to be affected. [en.wikipedia.org]

EPIDEMIOLOGY OF DAN The reported prevalence of DAN varies, depending on whether studies have been carried out in the community, clinic, or tertiary referral center. [care.diabetesjournals.org]

On the other hand, by understanding the pathophysiology, treatment success is possible by directing therapies toward the root causes and just as importantly, enlisting the patient in a daily treatment plan. [ncbi.nlm.nih.gov]

Keywords : fibromyalgia; autonomic nervous system; pathophysiology; rheumatic disease; adrenergic receptor; dystautonomia. [scielo.br]

This program is focused on studies of the pathophysiology of orthostatic intolerance and its amelioration. [mayo.edu]

“A critical review of the pathophysiology of dysautonomia following traumatic brain injury”. Neurocrit Care 8 (2): 293–300. doi:10.1007/s12028-007-9021-3. PMID 17968518. J Pediatr. 1999 Oct;135(4):494-9. [internationalpain.org]

Early management can help prevent comorbidities including secondary brain injury while also improving patient outcomes. [ncbi.nlm.nih.gov]

For example, a feeding tube inserted into the stomach can assist in feeding, and prevent fluids etc. from entering the lungs, while drugs are prescribed to prevent vomiting and seizures, eye drops lubricate dry eyes, and surgery can correct scoliosis. [brainfoundation.org.au]

This research aims to discover ways to diagnose, treat, and, ultimately, prevent these disorders. [web.archive.org]