Joint contractures sometimes develop and patients can be wheelchair-bound by the second decade. Dysarthric speech is common. No dysmorphic facial features are present. Brain imaging shows progressive cerebellar and sometimes cerebral atrophy. [disorders.eyes.arizona.edu]

Some patients may become wheelchair-bound as young adults (summary by Haack et al., 2016). [ncbi.nlm.nih.gov]

Intracranial Pressure Medical Terminology Ems Google Search Nurse Life Nurse Stuff Nurses Core School Nursing Forward “ Another great way to remember Decorticate Posturing is that you turn inwards toward your CORE. [pinterest.de]

In one Turkish family, affected people walk on their hands and feet (quadrupedal locomotion).Additional features of VLDLR-associated cerebellar hypoplasia include moderate to profound intellectual disability, impaired speech (dysarthria) or a lack of [ncbi.nlm.nih.gov]

Brain MRI shows cerebellar atrophy and ventriculomegaly (summary by Guergueltcheva et al., 2012). [ncbi.nlm.nih.gov]