Presentation
We report a case who presented to us with dyspnea and was found to have ML in the absence of steroid use, diabetes, Cushing syndrome and obesity. [ncbi.nlm.nih.gov]
Taylor presented some calculations she did based on 2018 AHA Health and Stroke Statistics. [healio.com]
Entire Body System
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Coronary Atherosclerosis
atherosclerosis. remnant hyperlipidemia a form in which the accumulated lipoproteins are normally transient intermediates, chylomicron remnants, and intermediate-density lipoproteins; a generic descriptor for the type III hyperlipoproteinemia phenotype [medical-dictionary.thefreedictionary.com]
Increased prevalence of subclinical coronary atherosclerosis detected by coronary computed tomography angiography in HIV-infected men. AIDS. 2010;24:243–253. [PMC free article] [PubMed] [Google Scholar] 7. Hadigan C, Meigs JB, Corcoran C, et al. [ncbi.nlm.nih.gov]
In support of this concept, recent analysis of the data of the Air Force/Texas Coronary Atherosclerosis Prevention Study (AFCAPS/TexCAPS) shows that baseline LDL-C, HDL-C, and apoB were significant predictors of first acute major coronary events but that [ahajournals.org]
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Resistant Hypertension
Clinical features of 8295 patients with resistant hypertension classified on the basis of ambulatory blood pressure monitoring. Hypertension., 57 (2011), pp. 898-902 [13] J.R. Banegas, L.M. Ruilope, A. de la Sierra, J.J. de la Cruz, M. Gorostidi, J. [revespcardiol.org]
Skin
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Xanthoma
C, Achilles tendon xanthomas. Notice the marked thickening of the tendons. D, Tendon xanthomas. E, Tuberous xanthomas. F, Palmar xanthomas. G, Eruptive xanthomas. [utmb.edu]
Patients with the homozygous form of familial hypercholesterolemia may have arcus corneae, tendinous xanthomas and xanthelasma plus planar or tuberous xanthomas. Planar xanthomas are flat or slightly raised yellowish patches. [merckmanuals.com]
Case 3 An 11-year-old girl presented with palmar xanthomas ( figure 1 ) and tubero-eruptive xanthomas of both elbows. Based on these clinical signs, she was diagnosed with type III HLP. [ncbi.nlm.nih.gov]
Workup
150 Borderline: 150–199 High: 200 Very high: 500 LDL 100 Near optimal: 100–129 Borderline high: 130 High: 160 Very high: 190 HDL 60 Low: 40 LDL/HDL ratio : the ratio of LDL and HDL levels serves as a control measure of cholesterol metabolism Further workup [amboss.com]
Stable angina is the initial clinical manifestation of nearly half of all patients with CAD, and given the high rates of myocardial infarction in patients with stable angina, extensive guidelines on workup and management, including stress testing, coronary [intechopen.com]
Treatment
treatment and control rates in rural China. [ncbi.nlm.nih.gov]
Prognosis
OBJECTIVE: To identify the changes caused by dyslipidemia and obesity in pregnancy suggesting causes for premature birth, and the prognosis for the newborn. [ncbi.nlm.nih.gov]
No studies have examined their impact on cardiovascular prognosis in patients with CRI.4 The use of this drug in dialysis patients was investigated mainly in Japan. [elsevier.es]
Prognosis The outlook for individuals with dysautonomia depends on the particular diagnostic category. [ninds.nih.gov]
What is the prognosis for dysautonomia? The outlook for individuals with dysautonomia depends on the particular diagnostic category. [my.clevelandclinic.org]
Etiology
Etiology: The prevalence of dyslipidemia in children age 12-19 was reported as approximately 20.3% in the CDC Morbidity and Mortality Weekly Report. [utmb.edu]
The identification of gene-diet associations is likely to provide useful information about the etiology of postmenopausal dyslipidemia and help in effective treatment. [ncbi.nlm.nih.gov]
Etiology Classification Fredrickson phenotype I IIa IIb III IV Condition Familial hyperchylomicronemia [6] Familial hypercholesterolemia [7] Familial combined hyperlipidemia [8] Familial dysbetalipoproteinemia [9] Familial hypertriglyceridemia [10] Frequency [amboss.com]
[…] risk of premature vascular disease.1,2 In addition, dyslipidemia is highly prevalent in children with nonalcoholic fatty liver disease and may play a role in its pathophysiology.3 Clinical dyslipoproteinemias Most dyslipidemias are multifactorial in etiology [unboundmedicine.com]
Epidemiology
Long-term, prospective epidemiologic studies have consistently shown that persons with healthier lifestyles and fewer risk factors for coronary heart disease, and particularly those with favorable lipid profiles, have reduced incidence of coronary heart [ncbi.nlm.nih.gov]
Pathophysiology
The endothelial changes that best illuminate the regional pathophysiology of atherosclerosis are not the different levels of NO and other molecular signals, but the regional reorganization of endothelial phenotypes in reaction to local hemodynamic forces [intechopen.com]
In that respect, our cohort allows perhaps the best possible model of this pathophysiologic complication of CKD in humans, making our findings generalizable to other populations with CKD.” – by Melissa J. [healio.com]
Pathophysiology of diabetic dyslipidemia: implications for atherogenesis and treatment. Clinical Lipidology. 2011;6(4):401-411. Google Scholar Jeppesen J, Hein HO, Suadicani P, Gyntelberg F. [panafrican-med-journal.com]
Clinical features Typically no specific signs or symptoms Skin manifestations Xanthoma : nodular lipid deposits in the skin and tendons Pathophysiology: Extremely high levels of triglycerides and/or LDL result in extravasation of plasma lipoproteins [amboss.com]
Pathophysiology of diabetic dyslipidemia: implications for atherogenesis and treatment. Clin Lipidol. 2011; 6: 401–411 Crossref Scopus (15) Google ScholarSee all References). [canadianjournalofdiabetes.com]
Prevention
Author information 1 NYU School of Medicine, NYU Center for Prevention of Cardiovascular Disease, Bellevue Hospital Lipid Clinic, National Lipid Association, New York, NY. 2 Johns Hopkins School of Medicine, Ciccarone Center for the Prevention of Heart [ncbi.nlm.nih.gov]
Session Title: Prevention: Risk Assessment in Primary Prevention Abstract Category: 24. Prevention: Clinical Presentation Number: 1232M-8 2013 American College of Cardiology Foundation [onlinejacc.org]