Presentation
Clinical guidelines recommend that endoscopy is not always required for diagnosis; a positive diagnosis of GORD and functional dyspepsia can be based on clinical presentation in the absence of alarm symptoms or features (see below). 3,4 In many cases [ueg.eu]
Undiagnosed dyspepsia: Patients presenting with dyspepsia symptoms that have not had investigations to determine whether the cause is organic or functional. 2. [empendium.com]
Dyspepsia and epigastric pain are common presenting symptoms of patients with either hookworm infection or peptic ulcer disease. [ncbi.nlm.nih.gov]
In this article and treatment algorithm, the author presents an optimal patient management approach. [jfponline.com]
Many patients respond well to explanation and reassurance that there is no serious underlying disease present. [ddc.musc.edu]
Entire Body System
- Anemia
Diagnostic studies: Perform the following to confirm or exclude an organic cause: 1) Complete blood count (CBC) (iron deficiency anemia is a red flag suggestive of an organic cause). 2) Abdominal ultrasonography (to be performed in patients with red flags [empendium.com]
A palpable abdominal mass Lymphadenopathy (e.g., left supraclavicular or periumbilical in gastric cancer) Jaundice (e.g., secondary to biliary obstruction, liver metastasis) Pallor (secondary to anemia) Labs: CBC, LFTs, Lipase Diagnostic strategies and [krhamaine.com]
Pernicious anemia: A form of anemia that occurs when the stomach lacks a naturally occurring substance that is needed to properly absorb and digest vitamin B12. [my.clevelandclinic.org]
↵ * Alarm symptoms are vomiting, bleeding or anemia, abdominal mass or unintended weight loss, and dysphagia (acronym: VBAD). [cmaj.ca]
- Malnutrition
People living with various forms of dysautonomia have trouble regulating these systems, which can result in lightheadedness, fainting, unstable blood pressure, abnormal heart rates, malnutrition, and in severe cases, death.” [ehlers-danlos.com]
People living with various forms of dysautonomia have trouble regulating these systems, which can result in lightheadedness, fainting, unstable blood pressure, abnormal heart rates, malnutrition, and in severe cases, death. Dysautonomia is not rare. [dysautonomiainternational.org]
[…] enteropathy Radiation damage Recent chemotherapy Graft-versus-host disease Chronic ischemia Cholera Crohn’s disease Helicobacter pylori infection Eosinophilic gastroenteritis Enteropathy caused by food allergy (in young children) Autoimmune enteropathy Severe malnutrition [worldgastroenterology.org]
Gastrointestinal
- Dyspepsia
Unspecified (non-specific) dyspepsia Symptoms do not fulfil the criteria for ulcer-like or dysmotility-like dyspepsia [9]. 2. [intechopen.com]
Dyspepsia and dyspepsia subgroups: a population-based study. Gastroenterology1992;102(4 pt 1):1259–68. ↵ Brown C, Rees WD. Dyspepsia in general practice. BMJ1990;300:829–30. ↵ Tebaldi M, Heading RC. [pmj.bmj.com]
‘Whether dyspepsia is becoming more common is unclear, but general practice consultations for non-ulcer dyspepsia have been increasing.’ ‘The procedure of choice for the evaluation of dyspepsia is endoscopy.’ [en.oxforddictionaries.com]
Functional dyspepsia (sometimes called non-ulcer dyspepsia) refers to a situation where UGI endoscopy did not reveal a potential cause for the dyspepsia. [bestpractice.bmj.com]
Overview Functional dyspepsia (dis-PEP-see-uh) is a term for recurring symptoms of an upset stomach that have no obvious cause. Functional dyspepsia also is called nonulcer dyspepsia. Functional dyspepsia is common. [mayoclinic.org]
- Nausea
Indigestion can cause stomach pain or bloating, or heartburn, nausea, and vomiting. [healthline.com]
Usually what is felt is nausea, pain in the pit of the stomach, vomiting and lots of burping. Dyspepsia is not a disease. However, it is an early sign or early symptom of a digestive disease. [herminahospitals.com]
Eating six small, low-fat meals per day may reduce early feelings of fullness, bloating after a meal, or nausea. Avoidance of caffeine, alcohol or smoking may also help. [aboutgimotility.org]
Review of systems seeks concomitant GI symptoms such as anorexia, nausea, vomiting, hematemesis, weight loss, and bloody or black (melanotic) stools. Other symptoms include dyspnea and diaphoresis. [merckmanuals.com]
- Abdominal Pain
‘A 48 year old man with a chronic complaint of dyspepsia suddenly develops severe abdominal pain.’ ‘They said that eradication of H pylori might be a cost effective treatment for non-ulcer dyspepsia in infected patients.’ [en.oxforddictionaries.com]
However, there was a greater reduction in abdominal pain/discomfort (8.8% vs 5.0%, P CONCLUSIONS: The use of GPA in patients on regular NSAIDs does not improve their overall dyspepsia, but it reduces abdominal pain and burping. [ncbi.nlm.nih.gov]
The gastroenterologists at the AMITA Health Digestive Health Institute understand your concerns and will work with you to treat your pain and discomfort. Our experts have treated countless routine cases of abdominal pain and indigestion. [amitahealth.org]
Dyspepsia is a medical term for the symptoms of chronic or recurrent upper abdominal pain or discomfort. [trihealth.com]
Definition Dyspepsia or "indigestion" is very broadly defined as recurrent upper abdominal pain, with or without bloating, nausea and vomiting. [apps.nhslothian.scot]
- Early Satiety
Overview Heartburn, acid regurgitation, excess of burping/belching, increased abdominal bloating, nausea, a feeling of abnormal or slow digestion, or early satiety are all symptoms that can be described by the term "dyspepsia". [cdhf.ca]
It may be described as indigestion, gassiness, early satiety, postprandial fullness, gnawing, or burning. [merckmanuals.com]
satiety and fullness) or epigastric pain syndrome that may occur irrespective of meals. [empendium.com]
Early satiety is a prevalent symptom in population-based surveys (5–11%).3,4 Unless specifically asked about, it may often be missed or misinterpreted as bloating, discomfort or fullness after eating. [nps.org.au]
- Regurgitation
Overview Heartburn, acid regurgitation, excess of burping/belching, increased abdominal bloating, nausea, a feeling of abnormal or slow digestion, or early satiety are all symptoms that can be described by the term "dyspepsia". [cdhf.ca]
There is consensus that heartburn and regurgitation are the cardinal symptoms of GERD if either or both are the only symptoms the patient complains of or are the dominant symptom.[1,2] There has been discussion about whether heartburn and regurgitation [medscape.com]
Burping up food or liquid (regurgitation). Burping. Most people will experience some symptoms of dyspepsia within their lifetimes. [healthlinkbc.ca]
Cardiovascular
- Hypertension
Hypertension was the most common co-morbid condition in our patients found in 29 (32.2%), while most of them don't have any co morbid condition. Duodenitis was found to be associated with tacrolimus use (p = 0.037). [ncbi.nlm.nih.gov]
Episodes of protracted vomiting attacks and hypertension termed 'autonomic crises'' can be recurrent. [orpha.net]
Excessive sympathetic activity can present as hypertension or a rapid pulse rate. Treatment There is usually no cure for dysautonomia. Secondary forms may improve with treatment of the underlying disease. [ninds.nih.gov]
Past medical history should include known GI and cardiac diagnoses, cardiac risk factors (eg, hypertension, hypercholesterolemia), and the results of previous tests that have been done and treatments that have been tried. [msdmanuals.com]
Excessive sympathetic activity can present as hypertension or a rapid pulse rate. Is there any treatment for dysautonomia? There is usually no cure for dysautonomia. Secondary forms may improve with treatment of the underlying disease. [my.clevelandclinic.org]
Neurologic
- Headache
Side effects of H2RAs may include headache, nausea, vomiting, constipation, diarrhea, and unusual bleeding or bruising. [patients.gi.org]
Side effects include: nausea and vomiting constipation diarrhea cough headache backache dizziness abdominal pain Both PPIs and H2 drugs are typically used to treat peptic ulcers. [healthline.com]
Melissa Locker, Southern Living, "The Fascinating Origins of Pepsi, North Carolina’s Hometown Favorite," 27 Feb. 2018 This has happened in cases of people with dyspepsia, irritable bowel syndrome, chronic pelvic pain, chronic prostatitis, fibromyalgia, headaches [merriam-webster.com]
Continue reading the main story Fever and Ague, Sick Headache, Sickness at the. Stomach, Constipation, Heartburn, Colic, Pains. in the Stomach or Bowels, Dysentery. Vomiting, a feeling of Faintness. and Lassitude, Want of. [nytimes.com]
Workup
Suitable workup and treatment are summarized. Funding and Disclosures Disclosure forms provided by the authors are available with the full text of this article at NEJM.org. Dr. [doi.org]
Treatment
Other treatments Other treatments for functional dyspepsia include complementary and alternative (CAM) therapies and psychotherapy. [encyclopedia.com]
A patient’s treatment will depend on symptoms. [trihealth.com]
Another type of antidepressant, selective serotonin reuptake inhibitors (SSRIs), have not been well studied for the treatment of FD, however they appear effective in the treatment of other functional digestive disorders. [iffgd.org]
Here, I discuss 10 common and/or high-impact mistakes that are made in the diagnosis and treatment of patients with dyspeptic symptoms: five related to diagnosis, five related to treatment. Comments [ueg.eu]
before and after the treatment. [ncbi.nlm.nih.gov]
Prognosis
Prognosis The outlook for individuals with dysautonomia depends on the particular diagnostic category. [ninds.nih.gov]
If indigestion is caused by lifestyle habits, the prognosis is good. Prevention of the lifestyle cause can often resolve the symptoms and cure your indigestion. [emedicinehealth.com]
What is the prognosis for dysautonomia? The outlook for individuals with dysautonomia depends on the particular diagnostic category. [my.clevelandclinic.org]
Etiology
In this study, we assessed the etiological factors, symptoms, physical signs and diadynamic methods in a case of chronic liver fluke disease with dyspepsia. [ncbi.nlm.nih.gov]
Compared with the general public, patients with FD have been found to have higher levels of anxiety, chronic tension, hostility, and hypochondriasis, and a tendency to be more pessimistic. 15 Possible causes of FD While the etiology of organic dyspepsia [jfponline.com]
The precise etiology of FD is unknown; although there are limited data to suggest that genetics, a prior infection, and environmental factors all play a role in symptom expression. [healio.com]
Epidemiology
The results of worldwide epidemiological studies have been unconvincing. No clear‐cut link has been documented between H. pylori and any specific symptom profile or pathophysiological mechanism in NUD. [doi.org]
Epidemiology, clinical characteristics, and associations for symptom-based Rome IV functional dyspepsia in adults in the USA, Canada, and the UK: a cross-sectional population-based study. [bestpractice.bmj.com]
[1] Mahadeva, S. and Goh, K.L. (2006) Epidemiology of Functional Dyspepsia: A Global Perspective. [scirp.org]
The results of worldwide epidemiological studies have been unconvincing. No clear-cut link has been documented between H. pylori and any specific symptom profile or pathophysiological mechanism in NUD. [ncbi.nlm.nih.gov]
Pathophysiology
Functional dyspepsia: Pathophysiologic mechanisms and their relation to symptom pattern Several pathophysiologic mechanisms explain underlie dyspeptic symptoms. [intechopen.com]
Frustratingly, symptoms of FD do not consistently predict underlying pathophysiology and do not reliably guide therapy. [healio.com]
Knowledge on pathophysiology of dyspepsia have been developing continuously since a scientific investigation has been started in 1980's, which considers Helicobacter pylori as one of key factor in managing dyspepsia, either it is associated with ulcer [ncbi.nlm.nih.gov]
This paper will review the current definitions of non-ulcer dyspepsia (NUD), pathophysiology, and guidelines for evaluation and management. [omicsonline.org]
All aspects of functional dyspepsia —from its definition and impact to pathophysiology and management— are covered in this online course by Lucas Wauters, Jan Tack and Tim Vanuytsel. [ueg.eu]
Prevention
[…] of Dyspepsia Changing your lifestyle is a preventative that can be done. [herminahospitals.com]
It is, therefore, crucial to detect and treat liver diseases early to halt liver damage and prevent possible complications. Dr. [bumrungrad.com]
Heartburn prevention. Mylanta Products. McNeil Consumer. www.mylanta.com/heartburn-prevention. Accessed June 2, 2013. Protect against heartburn. Prilosec OTC Product. [pharmacytimes.com]
Mint also helps in relieving indigestion and prevents buildup of gases in the stomach while cumin stimulates the secretion of pancreatic enzymes. Yogurt: Yogurt is the best remedy for any stomach bug. [lybrate.com]