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Early-Onset Nuclear Cataract


Presentation

  • The documents contained in this web site are presented for information purposes only. The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment.[orpha.net]
  • These opacities are present both in anterior and posterior cortex and their apices slowly progress towards the pupil. On oblique illumination these present a typical radial spoke-like pattern of greyish white opacities (Fig. 8.9).[ikeyes.blogspot.com]
  • In our present study, PSC was predominant with diabetes mellitus.[nature.com]
  • Amblyopia, if present, should be treated early.[disorders.eyes.arizona.edu]
  • These non-age-related changes of the crystalline lens can be classified as congenital or infantile (present within the first year of life), juvenile (within the first decade of life) or presenile cataract (present before the age of about 45 years). 3[reviewofoptometry.com]
Swelling
  • The eye may appear bloodshot with some swelling at first. Eventually these symptoms will resolve, although you may still need to wear a patch at night for some time. Most patients describe the entire process as nearly painless.[silversteineyecenters.com]
  • Many things can cause double vision, also called diplopia, including: brain tumor corneal swelling multiple sclerosis stroke cataracts Binocular double vision, which causes two images to be visible only if both eyes are open, can be a sign of serious[healthline.com]
  • The hypothesis is that, even in the presence of the osmotic stress caused by diabetes, compaction rather than swelling occurs in the nucleus of diabetic lenses.[bmcophthalmol.biomedcentral.com]
  • The final step is to inject salt water into the corneal wounds to cause the area to swell and seal the incision.[en.wikipedia.org]
  • Some people notice a phenomenon called "second sight" in which one's reading vision improves as a result of their increased nearsightedness from swelling of the cataract.[emedicinehealth.com]
Italian
  • July 21, 2009 In the July 28, 2009 issue of the journal Biochemistry, Italian researchers report that the dipeptide carnosine shows promise not only in preventing cataracts but also in helping to treat the condition.[lifeextension.com]
Diarrhea
  • Dehydrational crises from severe diarrhea or heatstroke and risk of cataract . Lancet 1984; 7 : 751–753. 12. Minassian DC , Mehra V , Reidy A . Childbearing and risk of cataract in young women: an epidemiological study in central India .[nature.com]
Dermatitis
  • Asthma and allergic dermatitis were the most common forms of atopy ( Table 2 ).[nature.com]
  • Cataracts in atopic dermatitis. These patients develops a shield like anterior subcapsular plaque. May also develop PSC. What is the most common cause of secondary cataract? Chronic anterior uveitis is the most common cause of this lens pathology.[quizlet.com]
  • Atopic dermatitis may be associated with presenile cataract (atopic cataract) in 10% of the cases. C. Mechanism of loss of transparency. It is basically different in nuclear and cortical senile cataracts. 1. Cortical senile cataract.[ikeyes.blogspot.com]
  • Atopic dermatitis, other diseases of the skin and mucous membranes, hypothyroidism, and hyperparathyroidism are associated with the early development of cataracts.[medicinenet.com]
  • Topical corticosteroids in atopic dermatitis & the risk of glaucoma & cataracts. J Am Acad Dermatol, 2011 Feb; 64(2): 275-81. 14. Xu L, You QS, Jonas JB.[jemds.com]
Blurred Vision
  • Cataract Symptoms If you are over the age of 60 and experiencing hazy, cloudy, or blurred vision, there is a good chance you may have cataracts. Early on, cataract symptoms can be very mild.[ophthalmicconsultants.com]
  • These fissures can cause the light that enters the eye to scatter, creating problems with blurred vision, glare , contrast, and depth perception. (See Vision Changes Related to Cataracts for more information.)[visionaware.org]
  • Over time, this area of blurred vision is likely to grow as your lens becomes more clouded. Eventually, you may get the sense that your overall vision is dull or blurry.[everydayhealth.com]
  • This condition scatters the light entering the eye and causing blurred vision, and glare, as well as difficulties in judging contrast and depth perception.[healthstatus.com]
  • Early changes may be very minor, but as this process continues, symptoms of blurred vision, light sensitivity, glare, and night driving difficulties increase. Types of cataract There are several types of cataract.[advancedeyecare.net]
Visual Impairment
  • Cataracts, which are characterized by a clouding of the eye's lens, are a major cause of visual impairment among older men and women, and surgery is currently the only effective treatment.[lifeextension.com]
  • International Senile cataract continues to be the main cause of visual impairment and blindness in the world.[emedicine.medscape.com]
  • Once your visual impairment progresses to the point that YOU feel your activities of daily living and enjoyment are impaired, this is the time to proceed to surgery. This threshold is very different between people.[discoveryeye.org]
  • Cataract treatment is based on the level of visual impairment they cause. If a cataract minimally affects vision, or not at all, no treatment may be needed.[aoa.org]
  • Worldwide, cataracts are the cause of half of all blindness, and one third of cases of visual impairment. The role of the lens is to help light focus onto the retina at the back of the eye.[focusclinics.com]
Progressive Loss of Vision
  • Cataract symptoms can include: cloudy or foggy vision blurry or distorted vision changes in colour vision frequent increases in eyeglass or contact lens prescriptions poor night vision (especially affected by headlights) progressive loss of vision halos[personaleyes.com.au]
  • Painless progressive loss of vision loss of vision 2. Greyish colour of lens 2. Greyish colour of lens 3. Iris shadow is present 3. Iris shadow is absent 4. Black spots against red 4.[ikeyes.blogspot.com]
Iridodonesis
  • Due to shrinkage of lens, anterior chamber becomes deep and iris becomes tremulous (iridodonesis).[ikeyes.blogspot.com]
Tremulousness
  • Due to shrinkage of lens, anterior chamber becomes deep and iris becomes tremulous (iridodonesis).[ikeyes.blogspot.com]
Mydriasis
  • Comparison of preoperative nepafenac (0.1%) and flurbiprofen (0.03%) eye drops in maintaining mydriasis during small incision cataract surgery in patients with senile cataract: A randomized, double-blind study.[emedicine.medscape.com]

Workup

  • See Workup for more detail. Management Lens extraction is the definitive treatment for senile cataract.[emedicine.medscape.com]

Treatment

  • The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment.[orpha.net]
  • The discovery means diagnosing Alzheimer’s could be done earlier and suggests new treatment targets for the debilitating disease.[dailymail.co.uk]
  • "Taken together, carnosine treatments showed a visible reversion of the effects of guanidine, either in preventive treatments or as recovery after lens opacification, supporting the notion that lens protein conformational changes, observed also in our[lifeextension.com]
  • Please contact our office today to learn more about cataracts and cataract treatment.[alohalaservision.com]
  • Your optometrist will determine what treatment is right for you.[healthstatus.com]

Prognosis

  • […] a very promising visual prognosis of gaining at least 2 lines in the Snellen distance vision chart.[emedicine.medscape.com]
  • What is the prognosis of cataracts? The rate of progression of cataracts is usually predictable and surgery is successful in restoring vision in a large majority of cases.[medicinenet.com]
  • Prognosis [ edit ] Postoperative care [ edit ] Slit lamp photo of anterior capsular opacification visible a few months after implantation of intraocular lens in eye, magnified view A South African woman experiences newfound eyesight after a patch was[en.wikipedia.org]

Etiology

  • Etiology Posterior polar cataracts are typically congenital and autosomal dominantly inherited. Symptoms Most posterior polar cataracts are asymptomatic or minimally symptomatic.[eyewiki.aao.org]
  • MAR 2001; 47 (3) : 491-497 Durupt-S; Durieu-I; Salles-B; Beaumont-C; Hot-A; Rousset-H; Durand-DV Increase in ferritin: the hyperferritinemia-cataract syndrome as a potential etiology REVUE-DE-MEDECINE-INTERNE.[malattierare.regione.veneto.it]
  • We hypothesized that hypermethylation of CpG islands in the CRYAA promoter underlies the etiology of HMC as well.[journals.plos.org]
  • Etiology Senile cataract is essentially an ageing process. Though its precise etiopathogenesis is not clear, the various factors implicated are as follows: A. Factors affecting age of onset, type and maturation of senile cataract. 1. Heredity.[ikeyes.blogspot.com]
  • […] exposure to UV radiation, smoking, genetic predisposition, diet, body mass index, systemic diseases, medications, ocular trauma and secondary ophthalmic disease. 4-13 While age-related cataracts are an asymmetric phenomenon, cataracts of non-age-related etiologies[reviewofoptometry.com]

Epidemiology

  • American Journal of Epidemiology. May 2005. Diabetes, hypertension, and central obesity as cataract risk factors in a black population: The Barbados Eye Study. Ophthalmology. January 1999.[allaboutvision.com]
  • Childbearing and risk of cataract in young women: an epidemiological study in central India . Br J Ophthalmol 2002; 86 : 548–550. 13. West SK , Valmadrid CT . Epidemiology of risk factors for age-related cataract .[nature.com]
  • It is not yet possible to confirm that antioxidants in the diet have a major role to play in the prevention of cataract formation, but epidemiologic studies suggests that it is wise to consume diets rich in vitamin C, E and carotenoids to prevent the[jemds.com]
  • Epidemiology of risk factors for age-related cataract. Surv Ophthalmol. 1995 Jan-Feb. 39(4):323-34. [Medline]. Miglior S, Marighi PE, Musicco M, Balestreri C, Nicolosi A, Orzalesi N.[emedicine.medscape.com]
  • Epidemiology and molecular genetics of congenital cataracts. Int J Ophthalmol. 2011;4(4):422-32. 22. Papania MJ, Wallace GS, Rota PA, et al.[reviewofoptometry.com]
Sex distribution
Age distribution

Pathophysiology

  • Pathophysiology The pathophysiology behind senile cataracts is complex and yet to be fully understood.[emedicine.medscape.com]

Prevention

  • Nutritional therapy can prevent the onset of cataracts, particularly because proven anti-cataract drugs are not available.[lifeextension.com]
  • Cataract Prevention Though there is significant controversy about whether cataracts can be prevented, a number of studies suggest certain nutrients and nutritional supplements may reduce your risk of cataracts.[allaboutvision.com]
  • It’s important to undergo routine eye exams and spot symptoms early to prevent such vision loss.[belmarrahealth.com]
  • Natural Cataract Symptoms Prevention and Treatment It’s said that cataracts aren’t completely preventable, but everyone seems to agree that their occurrence can definitely be delayed.[draxe.com]
  • While there are no clinically proven approaches to preventing cataracts, simple preventive strategies include: Reducing exposure to sunlight through UV-blocking lenses Decreasing or stopping smoking Increasing antioxidant vitamin consumption by eating[aoa.org]

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