Presentation
In the present study, nucleotide, amino acid, and phylogenetic analyses for all genomic regions were conducted. For the detection of recombination events, Simplot and bootscan analyses were carried out. [ncbi.nlm.nih.gov]
Generalized Disease of the Newborn Neonates often present with an illness resembling bacterial sepsis, with fever, irritability, and lethargy. [doctorslounge.com]
Gastrointestinal
- Diarrhea
At the time of the isolation of the viruses the diseases they caused were not known, hence the term “orphan,” but it is now known that they cause many different types of human disease, especially viral meningitis, diarrhea, and various respiratory diseases [medical-dictionary.thefreedictionary.com]
Clinical manifestations of neonatal echovirus type 18 infections include a nonspecific febrile illness, diarrhea, and meningitis with or without exanthem. [ncbi.nlm.nih.gov]
[…] being part of the enterovirus genus) and exposure to the virus causes other opportunistic infections and diseases. echovirus Noun 1. any of a group of viruses associated with various diseases including viral meningitis and mild respiratory disorders and diarrhea [italkit.co.il]
Musculoskeletal
- Arm Weakness
During a community echovirus type 33 outbreak, the virus was detected in the feces and cerebrospinal fluid of a 3-year-old boy with right arm weakness that followed a mild nonspecific febrile illness. [ncbi.nlm.nih.gov]
Urogenital
- Urinary Retention
She developed urinary retention with postvoid residual volumes of 450–500 mL, for which she required intermittent catheterizations. The results of additional viral blood cultures obtained on 19 June and 28 June were negative. [cid.oxfordjournals.org]
- Testicular Swelling
He presented to our institution, where he was febrile to 102.7°F with mild meningismus; testicular swelling and tenderness had resolved. [academic.oup.com]
Neurologic
- Focal Neurological Deficit
The CNS disease in newborns caused by EVs may also progress to meningoencephalitis with the appearance of seizures and focal neurological deficits [ 1, 2 ]. [virologyj.biomedcentral.com]
- Focal Seizure
Enteroviruses are rare causes of acute focal encephalitis. A fatal case of echovirus type 9 infection is reported in a 9 month old boy who presented with a fever and a macular rash followed by two focal seizures. [ncbi.nlm.nih.gov]
Workup
Microbiology
- Treponema Pallidum
pallidum Escherichia coli (postprocedure) [17] Mycobacterium tuberculosis a [18, 19] Nocardia species [20] Viruses Enterovirus Dengue virus Lymphocytic choriomeningitis virus [21] Epstein-Barr virus Mumps virus [22] Herpes simplex virus West Nile virus [academic.oup.com]
Treatment
Based on IVIg treatment failure, we predict that one of these factors could be immune related. [ncbi.nlm.nih.gov]
No specific treatment IMMUNIZATION: None available PROPHYLAXIS: None available; clinical trials using antiviral compound pleconaril (antipicornaviral agent) SECTION VI - LABORATORY HAZARDS LABORATORY-ACQUIRED INFECTIONS: Three cases were reported up [msdsonline.com]
There aren’t currently any antiviral treatments available for echovirus infection, but research is being conducted on possible treatments. Usually, there are no long-term complications. [healthline.com]
Prognosis
Prognosis Neonates with disseminated encephalitis have a poor prognosis and many die. Children and older patients have a better prognosis, but the disease is occasionally fatal. [emedicine.medscape.com]
Older children and adults have a better prognosis. Myocarditis is the most frequent complication in adults. Echovirus, like the other Enteroviruses Coxsackievirus A and B, typically causes a mild, nonspecific illness with a low fever. [en.wikipedia.org]
[…] immunosuppressed status exposure to others with echovirus public swimming pool Pathogenesis echovirus binds to decay-accelerating factor, a receptor the virus then replicates in Peyer’s patches it travels to regional lymph nodes and central nervous system Prognosis [medbullets.com]
Outlook (Prognosis) People who have the less severe types of illness should recover completely without treatment. Infections of organs such as the heart may cause severe disease and can be deadly. [nicklauschildrens.org]
Etiology
Thirty-four samples which were positive for enterovirus were subject to group-specific PCR, sequencing, and phylogenetic analysis to identify the etiological agent of the outbreak. [ncbi.nlm.nih.gov]
Epidemiology
KEYWORDS: Enterovirus; Germany; Lineages; Meningitis; Molecular epidemiology; RNA-sequencing; Recogroups; Recombination MeSH terms, Substance MeSH terms Cerebrospinal Fluid/virology Child Child, Preschool Disease Outbreaks* Echovirus Infections/epidemiology [ncbi.nlm.nih.gov]
Department of Virology and Epidemiology, Baylor College of Medicine, Houston, Texas. [accessscience.com]
Pathophysiology
Pathophysiology Human echoviral infection occurs via fecal-oral transmission. Host susceptibility depends on the presence of specific cellular membrane receptor proteins that bind different enteroviral types along taxonomic lines. [emedicine.medscape.com]
Prevention
Prevention The predominantly mild symptoms and the ubiquitous nature of these infections, means that preventative measures are not usually necessary or recommended. Back to Top [hps.scot.nhs.uk]
The measures taken to prevent further spread of infection with special reference to the use of human normal immunoglobulin are described. [ncbi.nlm.nih.gov]
Infection with an Echovirus cannot be directly prevented, and there’s no vaccine available. It can be challenging to control the spread of the virus. [healthline.com]