Type your tag names separated by a space and hit enter Abstract A rare case of congenital bilateral ectopia lentis et pupillae (ELEP) is reported in a 32 year old female presenting with complaints of diminution of vision in both eyes. [unboundmedicine.com]

A 27-year-old man presented with complaint of low visual acuity. No evidence of the syndrome was found at presentation. The results of supplementary tests were normal. [ncbi.nlm.nih.gov]

His visual acuity (VA) at presentation was 6/12 right with +14.50/−2.00×30 and 6/12 left with +14.50/−0.75×180. In March 1999 he re-presented complaining of intermittent blurred vision in his left eye. [nature.com]

The purpose of the present communication is to discuss the aetiopathogenesis of this condition and to highlight the specular microscopic changes of corneal endothelium which have never been reported earlier. [ijo.in]

The information presented is not intended to replace medical advice or treatment from your own doctor or healthcare provider. [wellnessadvocate.com]

• Pupillary Abnormality

  Our study presented detailed clinical manifestations, including some novel ophthalmic findings, such as pupillary abnormality, different types of glaucoma, and progressive hyperopia. [ncbi.nlm.nih.gov]

  Professor, Ulucanlar Eye Training and Research Hospital, Ankara/TURKEY Ectopia lentis et pupillae is a rare congenital hereditary disorder usually characterized with a combination of ectopia lentis and pupillary abnormalities, but without systemic manifestations [glaucomacataractjournal.com]

  There were no areas of iris atrophy, pupillary abnormalities, or iris transillumination in any of the 18 patients examined or their relatives. [cags.org.ae]

  Combined neuroectodermal and mesodermal origin is being postulated for this syndrome on the basis of aforesaid abnormalities and presence of pupillary dilator muscle hypoplasia, "annular endotheliopathy", and persistent pupillary membrane in both eyes [ijo.in]

• Arthralgia

  Clinical: Patients may have arthralgias, seizures, episodes of tetany, muscular weakness, or paresthesia; also may be asymptomatic. Al-Ghamdi SM, Cameron EC, Sutton RA. Magnesium deficiency: pathophysiologic and Clinical review. [uchebana5.ru]

• Screaming

  Dan let out a loud scream and immediately grabbed his eye. He was relieved to find out that he wasn't bleeding, however, his vision was very blurry and the eye was getting very swollen. [study.com]

An overview Signs and Symptoms Etiology of ectopia lentis Workup and evaluation Treatment Low Vision Management Conculsion Reference Workup and evaluation Sharma IP 34. Detailed history History of ocular trauma. [slideshare.net]

Twenty-four people presented for complete ophthalmological workups. In addition, complete detailed clinical examinations including echocardiography could be performed in six people ( Table 1 ). All mutation carriers showed ocular involvement only. [molvis.org]

The uveitis responded to treatment with g betamethasone q.d.s., but persisting raised IOP required the substitution of g latanoprost o.n. for dorzolamide. [nature.com]

Ectopia Lentis et Pupillae Syndrome: Treatment Treatment depends on how far the lens has been dislocated out of place. [study.com]

Treatment Treatment Options: Glaucoma, retinal detachments, and cataracts may require surgery. References Christensen AE, Fiskerstrand T, Knappskog PM, Boman H, Rodahl E. A novel ADAMTSL4 mutation in autosomal recessive ectopia lentis et pupillae. [disorders.eyes.arizona.edu]

The information presented is not intended to replace medical advice or treatment from your own doctor or healthcare provider. [wellnessadvocate.com]

An overview Signs and Symptoms Etiology of ectopia lentis Workup and evaluation Treatment Low Vision Management Conculsion Reference Treatment Sharma IP 40. [slideshare.net]

Diagnosis of the ectopia lentis et pupillae is fundamental not only to evaluate the risk, prognosis and treatment, but also to assist in differentiating other syndromes with systemic impairment. [ncbi.nlm.nih.gov]

Prognosis - Ectopia lentis isolated Not supplied. Treatment - Ectopia lentis isolated Not supplied. Resources - Ectopia lentis isolated Not supplied. [checkorphan.org]

Treatment and prognosis Complications An anterior dislocation/subluxation carries greater complications than a posterior one. Such complications include: acute glaucoma corneal injury iridal injury Promoted articles (advertising) [radiopaedia.org]

PROGNOSIS • Good visual prognosis with early intervention and routine follow-up. • Even in patients requiring lensectomy most achieve vision of 20/40 or better ( 1 ). – If not complicated by untreated amblyopia. [entokey.com]

Prognosis An individual’s prognosis depends on any underlying ocular or systemic disease, the degree of subluxation, and the management strategy pursued. [eyewiki.aao.org]

An overview Signs and Symptoms Etiology of ectopia lentis Workup and evaluation Treatment Low Vision Management Conculsion Reference Etiology of ectopia lentis Sharma IP 16. [slideshare.net]

As ectopia lentis may be the first sign of a more serious systemic disease, it is important to determine the etiology for appropriate patient management. [eyewiki.aao.org]

Pathology Etiology trauma systemic and syndromic disorders Marfan syndrome typically upwards and out most common spontaneous cause 2 homocystinuria - typically downwards Weil-Marchesani syndrome Ehlers-Danlos syndrome hereditary (or isolated) ectopia [radiopaedia.org]

Lyons, both globally recognized leaders, provide authoritative coverage of all the pediatric ophthalmic conditions you’re likely to encounter in practice, including the latest clinical advances in etiology, diagnosis, and medical and surgical management [books.google.de]

EPIDEMIOLOGY Incidence • Marfan disease 4–6/100,000 births ( 1 ) and approximately 60–75% have ectopia lentis. • Homocystinuria 1/200,000 births ( 1 ) and approximately 80–85% have ectopia lentis. Prevalence Unknown. [entokey.com]

Epidemiology Frequency  A rare condition.  Incidence in the general population is unknown. Mortality/Morbidity  Can cause marked visual disturbance, depending the degree of lens displacement and the underlying etiology Sex  More common in males. [slideshare.net]

Although no clear epidemiological data is available, it has been suggested that congenital EL may have a prevalence of six per 100 000. 22 It is probable that the second most common cause of EL is a condition termed isolated ectopia lentis (IEL). 22, [nature.com]

Pathophysiology  Underlying pathophysiology - Disruption or dysfunction of the zonular fibers of the lens, regardless of cause (trauma or heritable condition)  The degree of zonular impairment determines the degree of lens Sharma IP 10. [slideshare.net]

PATHOPHYSIOLOGY Weakening or stretching of the zonular attachments lens ( 1 ). [entokey.com]

A recent study of over thousand probands with Marfan syndrome and FBN1 mutations demonstrated a striking correlation between ectopia lentis and mutations affecting cysteine residues, leading to the speculation that the pathophysiology of ectopia lentis [molvis.org]

Magnesium deficiency: pathophysiologic and Clinical review. Am J Kidney Dis 1994; 24:737-752. Bourcier T, et al. Sclerochoroidal calcification associated with Gitelman syndrome. Am J Ophthalmol 1999; 128: 767-768. [uchebana5.ru]

And are not intended to diagnose, treat, cure or prevent disease. The information presented is not intended to replace medical advice or treatment from your own doctor or healthcare provider. [wellnessadvocate.com]

Prevention - Ectopia lentis isolated Not supplied. Diagnosis - Ectopia lentis isolated signs and symptoms of Ectopia lentis, isolated may vary on an individual basis for each patient. [checkorphan.org]

The bag-in-the-lens intra-ocular lens technique was used to accommodate this small ill-suspended capsule and to prevent secondary cataract formation in this young child. [escrs.org]

Prevent and plan for complications in advance by examining over 1,600 illustrations, photos and graphics (1,250 in color) capturing essential diagnostics techniques, imaging methods and surgical approaches. [books.google.ro]

Prevention and prognsis Deterrence/Prevention  Early diagnosis of ectopia lentis with appropriate optical correction can prevent amblyopia. [slideshare.net]