bruising without atrophic scarring. [orpha.net]

These symptoms include easy bruising, abnormally stretchy skin (hyperextensible), very loose joints with an abnormally large range of movement (hypermobility), and joints that dislocate/ subluxate easily. [diseaseinfosearch.org]

Possible diagnosis of EDS type VIII: Clinical features of EDS VIII such as hyperextensible joints, atrophic scarring, and easy bruising can often overlap with other forms of EDS. [uwcpdx.org]

[…] a Easy bruising; thin skin; androgenic alopecia LV enlargement Patient 11 F/31 SW 2 Hip laxity; chronic arthralgia a ; shoulder subluxation Easy bruising, wide scars Diagnosed with fibromyalgia at age 24 Patient 12 M/31 SW 0 Hypermobile fingers; multiple [academic.oup.com]

Consistent with the original description of tenascin-X deficiency, these individuals had marked skin hyperextensibility, easy bruising, and joint laxity. Unlike classical EDS they did not have atrophic scarring or poor wound healing. [unboundmedicine.com]

She has published over 570 original research articles. [books.google.com]

One of Kirk's most successful investments over the last year has been Halozyme ( HALO ). When Kirk first became involved with Halozyme in 2013, the company was trading around 5 a share. [stockmatusow.com]

Matthies The controversy over non-treatment of pain with pain medicine has filled the pages of pain advocacy journals in recent months. Our opinions, as people who live in pain and the doctors that treat us, are irrelevant. [edsinfo.wordpress.com]

There had been an ongoing argument with doctors over whether I have more of "classical types(1 & 2) or hypermobile type (3). Either way, having a complete lack of tenascin x is just as much of a pain in the rear. [inspire.com]

Therefore, patients should not rely on the “fact” of having a certain type of EDS if cross-over symptoms are evident because of possibly life-threatening symptoms. [intelligentdental.com]

[…] enlargement Sister of patient 9 F/15 SW 1 Hypermobile shoulders Normal Patient 10 F/22 SW 2 Hypermobile fingers; chronic arthralgia a Easy bruising; thin skin; androgenic alopecia LV enlargement Patient 11 F/31 SW 2 Hip laxity; chronic arthralgia a ; [academic.oup.com]

Its major criteria are a Beighton score of 4/9 or greater and arthralgia, but the diagnosis can also be based on the presence of minor criteria, including abnormal skin and joint (sub)luxations. [ard.bmj.com]

The mother of P2 (heterozygous for exon 35 120bp deletion) had hypermobile large and small joints and chronic arthralgia. [ncbi.nlm.nih.gov]

Case Records of the Massachusetts General Hospital Jun 28, 2018 Case 20-2018: A 64-Year-Old Man with Fever, Arthralgias, and Testicular Pain Sacks C.A., Kilcoyne A., Wallace Z.S., and Glomski K. [nejm.org]

Arthralgia for 3 months in 4 joints. Minor criteria Beighton score of 1, 2, or 3 out of 9 (or 0, 1, 2, or 3 if 50 years of age). Arthralgia in 1 to 3 joints or back pain, spondylosis, or spondylolysis/spondylolisthesis. [rheumatologyadvisor.com]

muscle weakness Weakness in muscles of upper arms and upper legs 0003701 Sensory neuropathy Damage to nerves that sense feeling 0000763 Skeletal muscle atrophy Muscle degeneration Muscle wasting [ more ] 0003202 Thin skin 0000963 5%-29% of people have [rarediseases.info.nih.gov]

Mitochondrial diseases An unusual group of adult-onset mitochondrial disease patients present with sporadic isolated myopathies, with exercise intolerance variably accompanied by proximal muscle weakness and myoglobinuria. [bredagenetics.com]

Other common features include foot and hand deformities (piezogenic papules, pes planus, broad forefeet, brachydactyly, and acrogenic skin of hands), severe fatigue and neuromuscular symptoms including muscle weakness and myalgia. [orpha.net]