Ehlers-Danlos syndrome type VIII. 61 Buckel T...Zaenglein AL 17461822 2007 20 Ehlers-Danlos syndrome type VIII: periodontitis, easy bruising, marfanoid habitus, and distinctive facies. 61 Moore MM...Schaffer JV 16843123 2006 21 Ehlers-Danlos type VIII [malacards.org]

Skin hyperextensibility was variable and all had skin fragility with easy bruising and scarring. [jaad.org]

Pediatr Dent 1993; 15: 212–213. 19 Moore MM, Votava JM, Orlow SJ, Schaffer JV : Ehlers-Danlos syndrome type VIII: periodontitis, easy bruising, marfanoid habitus, and distinctive facies. [nature.com]

Major criteria are: Severe progressive cardiac-valvular problems (aortic valve, mitral valve); Skin involvement: skin hyperextensibility, atrophic scars, thin skin, easy bruising; and Joint hypermobility (generalized or restricted to small joints). [ehlers-danlos.com]

Clinical features include lack of attached gingiva already present in childhood, easy bruising, pretibial haemosiderotic plaques, doughy skin, hoarse voice, poor wound healing, and hypermobility of joints. [frontiersin.org]

bleeding time. 61 Cunniff C...Williamson-Kruse L 7606321 1995 28 [Ehlers-Danlos syndrome and pregnancy]. 61 Flachowsky S...Kamin G 2278221 1990 29 [Oral manifestations of Ehlers-Danlos syndrome type VIII]. 61 Olesen BH...Ernst E 3475800 1987 30 Gingival [malacards.org]

Br Dent J 1979; 147: 95–96. 11 Cunniff C, Williamson-Kruse L : Ehlers-Danlos syndrome, type viii presenting with periodontitis and prolonged bleeding time. Clin Dysmorphol 1995; 4: 145–149. 12 Nelson DL, King RA : Ehlers-Danlos syndrome type VIII. [nature.com]

Ehlers-Danlos syndrome type VIII. 61 Buckel T...Zaenglein AL 17461822 2007 20 Ehlers-Danlos syndrome type VIII: periodontitis, easy bruising, marfanoid habitus, and distinctive facies. 61 Moore MM...Schaffer JV 16843123 2006 21 Ehlers-Danlos type VIII [malacards.org]

Pediatr Dent 1993; 15: 212–213. 19 Moore MM, Votava JM, Orlow SJ, Schaffer JV : Ehlers-Danlos syndrome type VIII: periodontitis, easy bruising, marfanoid habitus, and distinctive facies. [nature.com]

1 Two patients with Ehlers-Danlos syndrome type VIII with unexpected hoarseness. 61 56 6 27663155 2016 2 Fatal Ruptured Blood Blister-like Aneurysm of Middle Cerebral Artery Associated with Ehlers-Danlos Syndrome Type VIII (Periodontitis Type). 61 56 [malacards.org]

Clinical features include lack of attached gingiva already present in childhood, easy bruising, pretibial haemosiderotic plaques, doughy skin, hoarse voice, poor wound healing, and hypermobility of joints. [frontiersin.org]

6 Cikla U...Baskaya MK 25485215 2014 3 Ehlers-Danlos syndrome type VIII is clinically heterogeneous disorder associated primarily with periodontal disease, and variable connective tissue features. 61 56 6 Reinstein E...Curry CJ 22739343 2013 4 Periodontal [malacards.org]

EDSPD2 is characterized by the association of typical features of Ehlers-Danlos syndrome with gingival recession and severe early-onset periodontal disease, leading to premature loss of permanent teeth. [uniprot.org]

Abstract Ehlers–Danlos syndrome (EDS) type VIII (periodontitis type) is a distinct form of EDS characterized by periodontal disease leading to precocious dental loss and a spectrum of joint and skin manifestations. [nature.com]

Characteristic hyperpigmented pretibial plaques and premature periodontal disease, with gingival recession and irreversible destruction of periodontal tissues, were also seen in all five individuals. [jaad.org]

Mutations in C1R and C1S have been shown to cause an autosomal dominant disorder, periodontal EDS (EDSPD). [ctgt.net]

EDSPD2 is characterized by the association of typical features of Ehlers-Danlos syndrome with gingival recession and severe early-onset periodontal disease, leading to premature loss of permanent teeth. [uniprot.org]

Characteristic hyperpigmented pretibial plaques and premature periodontal disease, with gingival recession and irreversible destruction of periodontal tissues, were also seen in all five individuals. [jaad.org]

Several metal restorations are observed on primary teeth (b) as well as gingival recession and bacterial biofilm accumulation (d). [nature.com]

CH 295230 1979 16 A new variant of Ehlers-Danlos syndrome: an autosomal dominant disorder of fragile skin, abnormal scarring, and generalized periodontitis. 6 Stewart RE...Rimoin DL 890102 1977 17 Ehlers-Danlos Syndrome Type VIII: A Rare Cause of Leg Ulcers [malacards.org]

Association of Ehlers-Danlos syndrome and solitary rectal ulcer syndrome. Indian J Gastroenterol. 2007 May-Jun. 26 (3):149-50. [Medline]. Savasta S, Crispino M, Valli M, Calligaro A, Zambelloni C, Poggiani C. [medscape.com]

Jone reported a high risk of mucosal ulceration related to bracket positioning in a case of EDS (25). Pourshahidi et al. had spotted similar findings in another similar case under dental observation (26). [comprped.com]

Type VIII First described by Stewart and others in 1977,12 type VIII is characterized by generalized early-onset periodontitis and by large patches of scar tissue on the shins, similar to diabetic ulcers or varicose veins. [cda-adc.ca]

1 Two patients with Ehlers-Danlos syndrome type VIII with unexpected hoarseness. 61 56 6 27663155 2016 2 Fatal Ruptured Blood Blister-like Aneurysm of Middle Cerebral Artery Associated with Ehlers-Danlos Syndrome Type VIII (Periodontitis Type). 61 56 [malacards.org]