Rocky Mountain spotted fever has long been known to be endemic in North Carolina; cases of human ehrlichial infection were recognized there soon after Ehrlichia chaffeensis was recognized as an important cause of tick-borne disease in the southeastern [ncbi.nlm.nih.gov]

Fever, fatigue, malaise, headache, and other "flu-like" symptoms occur most commonly. Central nervous system involvement can result in seizures and coma. [mayomedicallaboratories.com]

These sera were collected from patients with symptoms of high fever. The rate of seropositivity for Orientia tsutsugamushi was 50.9% by IFA at the Public Health & Environmental Research Institute and National Institute of Health in South Korea. [ncbi.nlm.nih.gov]

Some patients may also have myalgias or arthralgias, and an estimated 10–40% of patients may develop coughing, pharyngitis, diarrhea, vomiting, abdominal pain, and changes in mental status. [en.wikipedia.org]

Although some infections are asymptomatic, most cause abrupt onset of an influenza-like illness with nonspecific symptoms such as fever, chills, myalgias, weakness, nausea, vomiting, cough. headache, and malaise, usually beginning about 12 days after [merckmanuals.com]

Patients infected with E. chaffeensis were more likely to present with 1 gastrointestinal symptom, cough, or rash than were persons infected with E. ewingii ( table 2 ). [academic.oup.com]

Fatal outcomes were significantly associated with being elderly; no administration of ribavirin; and the presence of a cough, hemorrhaging, and unconsciousness. [doi.org]

Abstract We report a case of ehrlichiosis in a 72-year-old man who developed extreme lethargy, acute renal failure requiring hemodialysis, and respiratory insufficiency requiring intubation. [ncbi.nlm.nih.gov]

The clinical features of both forms of human ehrlichiosis are identical and include nonspecific constitutional manifestations, such as fever, headache, malaise, nausea, vomiting, myalgia, and anorexia; however, rare patients develop neurologic symptoms [ncbi.nlm.nih.gov]

A 45-year-old man with a history of ankylosing spondylitis taking methotrexate presented to a community hospital with acute onset of nausea, vomiting and diarrhea. [jim.bmj.com]

Common clinical signs and symptoms of patients with HME (n 32) included fever (100%), headache (69%), myalgia (69%), rash (66%), nausea/vomiting (56%), altered mental status (50%) and lymphadenopathy (47%). [doi.org]

Early Illness Early signs and symptoms (the first 5 days of illness) are usually mild or moderate and may include: Fever, chills Severe headache Muscle aches Nausea, vomiting, diarrhea, loss of appetite Confusion Rash (more common in children) Rash Up [cdc.gov]

Using a freeze fracture technique and biochemical analysis, these bacteria were found to contain significant levels of membrane cholesterol. These bacteria lack genes for cholesterol biosynthesis or modification. [ncbi.nlm.nih.gov]

Author information 1 Infectious Disease Division, Winthrop-University Hospital, Mineola, NY, USA. [email protected] Abstract Bilateral anterior thigh pain may indicate bacteremia (Louria's Sign). [ncbi.nlm.nih.gov]

Clinical findings include fever, headache, myalgia, leukopenia, thrombocytopenia, and hepatic inflammatory injury. Whereas Ehrlichia chaffeensis (HME) often causes meningoencephalitis, this is rare with Anaplasma phagocytophilum infection. [ncbi.nlm.nih.gov]

Case Presentation: A 47year old Caucasian man came to the emergency room with of fever, severe headaches, severe body aches and pain for 4days. Headaches worsened and he developed photophobia on day 5. [shmabstracts.com]

We report two cases of rapidly fatal Ehrlichia chaffeensis infection in patients who presented to our institution in early June.A 22-year-old man was hospitalized with hypotension after a one-week illness characterized by fever, headache,. .. [nejm.org]

Author information 1 Infectious Disease Division, Winthrop-University Hospital, Mineola, NY, USA. [email protected] Abstract Bilateral anterior thigh pain may indicate bacteremia (Louria's Sign). [ncbi.nlm.nih.gov]

We describe a patient with HME who developed a trochlear nerve paresis associated with evidence of lymphocytic meningitis during the course of her illness. [ncbi.nlm.nih.gov]

Patients developed characteristic manifestations of severe disease due to E. chaffeensis, including marked thrombocytopenia, pulmonary insufficiency, and encephalopathy. Primary isolation was achieved in DH82 cells; the Jax and St. [ncbi.nlm.nih.gov]