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Eikenella Corrodens

Eikenella Corrodens Infection


Presentation

  • Clinical examinations were carried out at 6 sites of every tooth present.[ncbi.nlm.nih.gov]
  • Abstract We present the case of a seemingly spontaneous septic hip arthritis in a patient with no pertinent medical history.[ncbi.nlm.nih.gov]
  • A 39-year-old woman with diabetes mellitus type 2 and hyperlipidemia presented with difficulty ambulating as well as pain and swelling of her right foot.[ncbi.nlm.nih.gov]
  • In this report, we present present a case of neonatal conjunctivitis caused by E. corrodens.[ncbi.nlm.nih.gov]
  • The epidemiology, microbiology, common clinical presentations and therapy of E. corrodens are reviewed. A brief summary of the extent of toothpick injuries and their infectious complications are also presented.[ncbi.nlm.nih.gov]
Tachycardia
  • The patient presented to the emergency department 9 days postoperatively with high fevers, tachycardia, and crepitus along his abdominal wall.[ncbi.nlm.nih.gov]
Mitral Valve Prolapse
  • A 69-year old man with clinically silent mitral valve prolapse developed infective endocarditis secondary to Eikenella corrodens after dental work. The patient required surgical removal of abscessed teeth and long-term antibiotic therapy.[ncbi.nlm.nih.gov]
Acute Low Back Pain
  • This is the first reported case of E. corrodens intervertebral diskitis causing acute low back pain. Recognition of this organism in this condition emphasizes the importance of aerobic and anaerobic cultures of infected disks.[ncbi.nlm.nih.gov]
Neck Pain
  • A 65-year-old man from Indonesia developed slowly progressive vertebral collapse and worsening neck pain. History suggested a previous pharyngeal injury while eating fish.[ncbi.nlm.nih.gov]
Eruptions
  • On arrival, he was in shock, and a purpuric eruption was noted on both legs.[ncbi.nlm.nih.gov]
Skin Lesion
  • Cultures of the exudates from skin lesions and histopathological samples did not identify any pathogens, and histopathological findings showed arterial thrombosis; therefore it was concluded that the second time shock was associated with purpura fulminans[ncbi.nlm.nih.gov]
Apathy
  • We report the case of a 61-year-old homosexual male who came to our observation because of a recent onset occipital and left frontoparietal headache, weakness, anorexia, hyperosmia and hypergeusia and psychomotor slowing, apathy and fatuous behavior.[ncbi.nlm.nih.gov]

Workup

Chlamydia Trachomatis
  • Neonatal bacterial conjunctivitis is caused by many species of bacteria, the most important being Neisseria gonorrhoea and Chlamydia trachomatis. Eikenella corrodens is a Gram-negative bacillus.[ncbi.nlm.nih.gov]
Actinomyces Israelii
  • The following indicators were used: Porphyromonas gingivalis FDC381, Prevotella intermedia ATCC25611, Actinomyces israelii ATCC12102, Eubacterium lentum ATCC25559, Peptostreptococcus anaerobius ATCC27337, Actinobacillus actinomycetemcomitans FDCY4, Fusobacterium[ncbi.nlm.nih.gov]

Treatment

  • First-line treatment for such infections is penicillins and cephalosporins; however, in a patient with penicillin allergy, treatment options become limited, as there is potential cross-reactivity with other agents.[ncbi.nlm.nih.gov]
  • Empirical treatment of pyogenic liver abscess will most often cover Eikenella corrodens, but the recommended treatment is a third generation cephalosporin or a fluoroquinolon.[ncbi.nlm.nih.gov]
  • It is of paramount importance that clinicians search for an infective cause of an inflammatory pseudotumour, to ensure appropriate treatment.[ncbi.nlm.nih.gov]
  • Awareness of unusual bacteria as potential causative organisms of osteomyelitis is imperative for appropriate treatment.[ncbi.nlm.nih.gov]
  • Complete recovery was achieved with surgical treatment and antimicrobial therapy.[ncbi.nlm.nih.gov]

Prognosis

  • The prognosis of the disease, despite introduction of appropriate antibiotic therapy, was poor as he refused to undergo cardiac surgery.[ncbi.nlm.nih.gov]
  • These results confirm previous reports that HACEK endocarditis portends a favorable prognosis.[educus.com]
  • In contrast to NP in adult patients with poor prognosis, pediatric patients with NP can be treated safely using antibiotic therapy with complete recovery. 5 Surgical intervention of NP has been limited to decortication of entrapped lung, anaerobic bacteria[scielo.br]
  • However, it is clear that the prognosis for periodontal health after dental treatment is much better for patients whose blood sugar levels are well controlled.[herenciageneticayenfermedad.blogspot.com]

Etiology

  • E. corrodens may be the cause of apparently sterile brain abscesses encountered in neurosurgery and should be considered in the differential etiology of brain abscess.[ncbi.nlm.nih.gov]
  • The etiologies have been attributed to chemical, bacterial, and viral agents. Neonatal bacterial conjunctivitis is caused by many species of bacteria, the most important being Neisseria gonorrhoea and Chlamydia trachomatis.[ncbi.nlm.nih.gov]
  • Eikenella corrodens, normally existing as a commensal in the mouth and the upper respiratory tract, is identified as an etiologic pathogen of endocarditis very rarely.[ncbi.nlm.nih.gov]
  • Taxonomic and experimental evidence that supports an infectious etiology are presented.[ncbi.nlm.nih.gov]
  • That microorganism continues to be a rare etiological agent. We report the case of a female patient with native valve, who had Eikenella corrodens infective endocarditis.[scielo.br]

Epidemiology

  • The epidemiology, microbiology, common clinical presentations and therapy of E. corrodens are reviewed. A brief summary of the extent of toothpick injuries and their infectious complications are also presented.[ncbi.nlm.nih.gov]
  • The data obtained in this analysis showed clonal divergence among members of the E. corrodens species, at the same time revealing this pulsed-field gel electrophoresis as being a highly attractive procedure for epidemiological investigation of this organism[ncbi.nlm.nih.gov]
  • Infection Control & Hospital Epidemiology ISSN: 0899-823X EISSN: 1559-6834 URL: /core/journals/infection-control-and-hospital-epidemiology[cambridge.org]
  • --epidemiologic and mechanistic evidence linking periodontal infections and atherosclerosis. Journal of Dental Research. 89(9): 879-902. Kumada, H., Kondo, S., Umemoto, T., & Hisatsune, K. 1993.[revistas.unal.edu.co]
  • Thus REA proved to be a useful technique in the epidemiologic search for E. corrodens infections [6]. References 1. Amano, T. Kishima, S. Kimura, M. Takiguchi, T. Ooshima, S. Hamada, I. Morisaki.[microbewiki.kenyon.edu]
Sex distribution
Age distribution

Prevention

  • Educational efforts aimed at preventing exposure of traumatized skin to oral secretions can minimize the risk of E. corrodens infections in compromised hosts.[ncbi.nlm.nih.gov]
  • Staphylococcus aureus biofilms prevent macrophage phagocytosis and attenuate inflammation in vivo. J Immunol. 2011; 186:6585–6596. Hanke ML, Angle A, Kielian T.[nzma.org.nz]
  • Optimisation of the prevention and treatment of bacterial endocarditis. Drugs Aging 2001; 18: 415-24. [ Links ] 7. Wilson WR, Karchmer AW, Dajani AS et al.[scielo.br]

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