A review of the literature on germ cell testicular tumor in men sixty years old and over is also presented. [ncbi.nlm.nih.gov]

However, it is present as a component of almost ninety percent of mixed nonseminomatous germ cell tumours. The average age at diagnosis is 31 years, and typically presents as a testicular lump which may be painful. [en.wikipedia.org]

• Epigastric Pain

  Here we describe a 72-year-old man who remained undiagnosed for a prolonged period of time because of intractable epigastric pain. [ncbi.nlm.nih.gov]

• Suggestibility

  Some studies suggest a single consecutive progression from intratubular germ cell neoplasia, unclassified (IGCNU), to seminoma and then to embryonal carcinoma; others suggest that seminoma and embryonal carcinoma derive independently from IGCNU. [ncbi.nlm.nih.gov]

  The changes observed in xenografts were associated with decreased PPARβ/δ-dependent expression of proliferating cell nuclear antigen and octamer-binding transcription factor-3/4, suggesting suppressed tumor proliferation and induction of differentiation [oncotarget.com]

• Polyneuropathy

  Abstract Neuropathy target esterase (NTE) is a protein involved in the development of a polyneuropathy caused by exposure to certain organophosphorus compounds. [ncbi.nlm.nih.gov]

• Secondary Amenorrhea

  The case of a 12-year-old female with a history of secondary amenorrhea for 6 months is reported; her symptoms included decreased visual acuity, dizziness and postprandial vomiting over a 1-month period. [ncbi.nlm.nih.gov]

The patient elected observation after further workup showed no evidence of metastasis.A repeat ultrasound 3 months later showed interval growth and the patient underwent right radical orchiectomy. [ncbi.nlm.nih.gov]

Review Topic QID: 106375 5 No further workup, instruct patient to return if symptomatic M1 Select Answer to see Preferred Response PREFERRED RESPONSE 2 Sorry, this question is for PEAK Premium Subscribers only ARTICLES (4) Topic COMMENTS (12) Please login [step1.medbullets.com]

• Karyotype Abnormal

  As evidences suggesting the role of karyotypic abnormalities (e.g., aneuploidy and near-tetraploidy) and stem cell in tumor development are increasing, it becomes pertinent to study karyotypically abnormal embryonal carcinoma cells. [ncbi.nlm.nih.gov]

We report a rare case of advanced testicular cancer that describes the natural progression of testicular cancer without medical treatment. [ncbi.nlm.nih.gov]

The prognosis is very poor for patients with teratocarcinoma, embryonal carcinoma, or choriocarcinoma, despite aggressive therapy. [ncbi.nlm.nih.gov]

A component of embryonal carcinoma is often found in mixed germ-cell tumors, in which case it is usually the most aggressive component, and dictates prognosis. [radiopaedia.org]

ETIOLOGY •Embryonal carcinoma is a NON-SEMINOMATOUS germ cell tumour characterized by primitive epithelial cells with marked pleomorphism and various histologic patterns. It may present in pure form but often is part of a mixed germ cell tumour. [slideshare.net]

(Etiology) The cause of Embryonal Carcinoma of the Testis is unknown. [dovemed.com]

About 3-10% of pure germ cell tumors are embryonal carcinomas, and embryonal carcinomas are present in more than 80% of mixed germ cell tumors. [1, 2] Etiology Genetic and environmental factors play a role in the development of germ cell tumors, [3, 4 [emedicine.medscape.com]

Epidemiological studies evidenced an increased incidence of testicular germ cell cancer after elevated pre-natal estrogen exposure but the expression of estrogen receptors in these testicular neoplasms has not been well elucidated. [ncbi.nlm.nih.gov]

[…] cells recapitulating early stages of embryonic development Essential features Age at presentation: 30's Pure in 2% of the cases; most commonly part of mixed germ cell tumor More than 60% have metastases at presentation Multiple morphologic patterns Epidemiology [pathologyoutlines.com]

Introduction Testicular tumors can be of germ cell or non-germ cell origin germ cell origin are the majority (95%) and are more commonly malignant non-germ cell origin usually benign Epidemiology incidence most common cancer in men between 15-35 years [step1.medbullets.com]

Epidemiology Embryonal carcinoma is one of the most common germ cell tumors. The peak incidence occurs in persons aged 20-30 years. It is extremely rare in infants. [emedicine.medscape.com]

Maintaining Foxm1 expression prevents the downregulation of pluripotency-related transcription factors such as Oct4 and Nanog during P19 cell differentiation. [ncbi.nlm.nih.gov]

Hopefully it prevents an infection. I have a son in jr. kindergarten, so infections are always a possibility in this house. Vicfirth: I have been following your threads and I hope that you won�t need to go down this road. [tc-cancer.com]

Cancer Detection and Prevention 6:119–130 Google Scholar Vawter GF, Tefft M (1966) Congenital tumors of the parotid gland. [link.springer.com]

Removal of the testis Debulking surgery to reduce tumor size, followed by chemotherapy Clotting the vessels in the tumor (embolization) Chemotherapy Radiotherapy Undertaking treatment of underlying conditions How can Embryonal Carcinoma of the Testis be Prevented [dovemed.com]