In conclusion, our findings support the hypothesis that neurological features are present in all types of cretins, and are the consequence of maternal and fetal hypothyroxinemia due to severe iodine deficiency. [ncbi.nlm.nih.gov]

The new points contributed by the present work in the study of African myxedematous cretinism are as follows: 1) The thyroid scannings, which show the presence of small thyroid glands. [thieme-connect.com]

• Disproportionate Dwarfism

  This offensive term should be avoided. cretinism (krē´tənizəm) (congenital hypothyroidism), cretinism arrested physical and mental development with dystrophy of bones and soft tissues, resulting in disproportionate dwarfism. [medical-dictionary.thefreedictionary.com]

• Abnormal Dermatoglyphic Pattern

  Abstract We have tested the hypothesis that the abnormal development of the central nervous system seen in endemic cretinism might be accompanied by concurrent abnormal dermatoglyphic patterns. [ncbi.nlm.nih.gov]

• Suggestibility

  These findings suggest that neurologic damage is very similar in all forms of endemic cretinism, reflecting a diffuse insult to the developing fetal nervous system. [ncbi.nlm.nih.gov]

• Babinski Sign

  Nevertheless, all myxedematous cretins had some neurologic disorders (hyperreflexia, increased muscle tone, disorder of gait, Babinski sign, hypoacusia) that were similar to those present in neurologic cretins. [ncbi.nlm.nih.gov]

  Vestibular function was sluggish in 96 per cent; gait was abnormal in 77.8 per cent, 46.1 per cent had a positive Babinski sign; 35.2 per cent had upper motor neuron paralysis; and many showed severe deformity of the extremities. [archive.unu.edu]

• Meningism

  Nervous system Meninges Brain Spinal cord Peripheral nerves 9. Musculature 10. The skeleton General restriction in growth Physical proportions Development Bone form relationships Skull Trunk Upper limbs Lower limbs 11. Joints 12. Teeth 13. [bokus.com]

• Hyperreflexia

  Nevertheless, all myxedematous cretins had some neurologic disorders (hyperreflexia, increased muscle tone, disorder of gait, Babinski sign, hypoacusia) that were similar to those present in neurologic cretins. [ncbi.nlm.nih.gov]

[…] lateral radiograph of the knee may be obtained to look for the distal femoral epiphysis; this ossification center appears at about 36 weeks' gestation, and its absence in a term or postterm infant indicates prenatal effects of hypothyroidism. [16] See Workup [emedicine.medscape.com]

It can be prevented by iodine treatment before conception, but whether it can be prevented or ameliorated by treatment during pregnancy or after delivery is not known. [ncbi.nlm.nih.gov]

It can be prevented by iodine treatment before conception, but whether it can be prevented or ameliorated by treatment during pregnancy or after delivery is not known. METHODS. [hero.epa.gov]

The interval from iodine treatment until delivery was used to define the trimester of treatment. [nejm.org]

PROGNOSIS Depends on: Early diagnosis Proper counselling Strict diet control Careful monitoring Compliance 32. [slideshare.net]

Cretinism Prognosis Early diagnosis of the disease leads to better prognosis. The newborns that are diagnosed and treated within their first month of life usually have normal intelligence. [howshealth.com]

Cretinism Prognosis When treated early, the outcome is good. Newborns diagnosed and treated within the first few weeks after birth generally have normal intelligence. [primehealthchannel.com]

Improved prognosis in congenital hypothyroidism treated before age three months. J Pediatr. 1972 Nov. 81(5):912-5. [Medline]. Klein AH, Agustin AV, Foley TP Jr. Successful laboratory screening for congenital hypothyroidism. [emedicine.medscape.com]

Etiology, pathogenesis and developmental sequelae of the condition are discussed and the physical and psychological characteristics are delineated. [researchers.mq.edu.au]

The data indicate an autosomal recessive predisposition as a major etiological factor. [ncbi.nlm.nih.gov]

Most investigators maintain the opinion that the primary etiological factor is iodine deficiency. The thyroid enlarges as a result of this deficiency, and with chronic stimulation it becomes nodular in the course of time. [popline.org]

Cretinism Etiology Lack of thyroid hormones is the cause. [primehealthchannel.com]

Etiology of Hypothyroidism ACQUIRED Iodine deficiency Auto-immune thyroiditis Thyroidectomy or RAI therapy TSH or TRH deficiency Medications (iodide & Cobalt) Idiopathic 5. [slideshare.net]

Search for more papers by this author First published: August 1969 Cited by: 4 SUMMARY A study has been carried out of the clinical features, epidemiology and thyroid function in 254 cases of endemic cretinism in Eastern New Guinea. [onlinelibrary.wiley.com]

Pediatrics and of Radioisotopes, Brussels University and IRSAC[ *** ], Lwiro, Democratic Republic of the Congo Further Information Publication History Publication Date: 08 January 2009 (online) Abstract The aim of the present work is to describe the epidemiological [thieme-connect.com]

Neurologic Consequences of Malnutrition begins with an overview of the epidemiology and incidence of malnutrition and neurologic disorders. [books.google.ro]

AMERICA CENTRAL IODINE EPIDEMIOLOGIA PATOLOGIA EPIDEMIOLOGIE PATHOLOGIE EUROPE AMERIQUE DU NORD AMERICA DEL SUR THERAPEUTIQUE AMERICA DEL NORTE OCEANIE CENTRAL AMERICA MORBIDITE ASIE DU SUD EST NORTH AMERICA ENDOCRINE DISEASES OCEANIA BOCIO SOUTH AMERICA EPIDEMIOLOGY [agris.fao.org]

In conclusion, our hypothesis states that the clinical expression of endemic cretinism is determined by the sum of two pathophysiologic processes. [ncbi.nlm.nih.gov]

In conclusion, our hypothesis states that the clinical expression of endemic cretinism is determined by the the sum of two pathophysiologic processes. [liebertpub.com]

[…] of Medicine, University of Adelaide ; now Foundation Professor of Social and Preventive Medicine, Monash University, Melbourne. [onlinelibrary.wiley.com]

It can be prevented by iodine treatment before conception, but whether it can be prevented or ameliorated by treatment during pregnancy or after delivery is not known. [ncbi.nlm.nih.gov]

Endemic cretinism remains a major preventable cause of intellectual and physical disability in isolated communities in Third World countries. [researchers.mq.edu.au]

It can be prevented by iodine treatment before conception, but whether it can be prevented or ameliorated by treatment during pregnancy or after delivery is not known. METHODS. [hero.epa.gov]