Presentation
The salient features of this condition are present in the case presented here of a 14-year-old boy who died from progressive heart failure due to right ventricular EMF. [ncbi.nlm.nih.gov]
Entire Body System
- Turkish
We report a case of right ventricular endomyocardial fibrosis mimicking Ebstein anomaly in a 26-year-old male Turkish patient with Behçet's disease, who had heart failure symptoms. [ncbi.nlm.nih.gov]
- Hyperthermia
Search for other works by this author on: Hubert Cochet A 20-year-old man with past history of Ebstein Barr Virus-associated lymphoma at the age of 15, currently in remission, presented to the emergency department with acute abdominal pain, nausea, hyperthermia [academic.oup.com]
Respiratoric
- Respiratory Distress
The newborn weighed 3,400 g and had progressive respiratory distress right after birth. [scielo.br]
Cardiovascular
- Heart Disease
Rheumatic heart disease and endomyocardial fibrosis: Distinguishing the etiology of mitral regurgitation in low-resourced areas Abstract Rheumatic heart disease (RHD) and endomyocardial fibrosis (EMF) are 2 neglected cardiovascular diseases that disproportionately [journals.ac.za]
We report this rare case of mitral valve prolapse in EMF, in a geographical area where rheumatic heart disease is endemic, to showcase how a rare manifestation of EMF can be misdiagnosed as that of rheumatic heart disease. [ncbi.nlm.nih.gov]
Necropsy study of endomyocardial fibrosis and rheumatic heart disease in Uganda 1950-1965. Br Heart J. May 1968;30(3):391-401. ↑ Smedema JP, Winckels SK, Snoep G, et al. [wikidoc.org]
Clinical features depend on stage of disease and anatomical involvement of the heart. [nigjcardiol.org]
In endemic areas of Africa endomyocardial fibrosis is as common a cause of heart failure as rheumatic heart disease, accounting for up to 20% of cases of heart failure and imposes a considerable burden to the communities and the health systems. [globalcardiologyscienceandpractice.com]
Eyes
- Diplopia
The electrocardiogram (ECG) showing deep inferolateral T-wave inversion A 43-year-old male presented to the Emergency Department with a five-day history of diarrhoea, vomiting, intermittent diplopia and headaches. [bjcardio.co.uk]
Psychiatrical
- Withdrawn
Extracorporeal circulation was withdrawn with the help of vasoactive drugs (dobutamine and milrinone) and of an epicardial pacemaker for total atrioventricular block. [scielo.br]
Breast
- Breast Atrophy
Physical examination was remarkable for 'egg on stick appearance', central cyanosis, generalized hyper pigmentation, breast atrophy, parotid fullness, and bilateral pitting leg edema. [nigjcardiol.org]
Workup
European citizens with no history of travelling to tropical countries. 3 Some of these reports have communicated severely calcified forms of this disease. 4 We would like to state that an exhaustive evaluation was performed to complete the diagnostic workup [revespcardiol.org]
Other Pathologies
- Myocardial Fibrosis
A 50-year-old female patient with endo- myocardial fibrosis presented with unusual calcifications of the right ventricular endocardium that embedded the tricuspid valve papillary muscles. [ncbi.nlm.nih.gov]
fibrosis and focal myocardial fibrosis. [wikidoc.org]
Finally, on cardiac MRI subendocardial late gadolinium hyperenhancement was observed in the left ventricular apex ( Figure 1 D, arrow), reflecting myocardial fibrosis. The patient's clinical context supports the diagnosis of an initial stage of EF. [elsevier.pt]
Diagnosis: “Endo myocardial fibrosis.” The correspondent author’s postmortem report External appearances: The body was that of an emaciated young man who was very pale. The ankles pitted on pressure. [scitcentral.com]
Jugular Venous Pressure
- Prominent A-Wave
In this case, the only abnormal clinical finding may be a giant or prominent 'a' wave in the jugular venous pulse. [nigjcardiol.org]
Treatment
Outcome was favorable under treatment with prednisone and azathioprine.This case illustrates a favorable outcome of endomyocardial fibrosis during pregnancy. [ncbi.nlm.nih.gov]
Acute eosinophilic myocarditis: diagnosis and treatment. Acute Card Care. 2010; 12 (1):31-36. doi: 10.3109/17482940903578998 [CrossRef] [PubMed] 3. Kawano S, Kato J, Kawano N, et al. [jaoa.org]
Prognosis
Endomyocardial fibrosis carries a poor prognosis, due to the late presentation of patients. [ncbi.nlm.nih.gov]
Etiology
The etiology, pathogenesis, echocardiographic findings, interventions and prognosis are quite distinct. [journals.ac.za]
Endomyocardial fibrosis (EMF) is a neglected tropical cardiomyopathy of unknown etiology and pathogenesis that is common in certain tropical areas of Africa, Asia, and South America. It affects predominantly children and young adults. [ncbi.nlm.nih.gov]
Various infections and toxic factors were postulated regarding its etiology. [scopemed.org]
Epidemiology
However, due to lack of resources for research in these areas, the exact epidemiology, etiology and pathogenesis remain unknown, and the natural history is incompletely understood. [globalcardiologyscienceandpractice.com]
Due to lack of resources for research in the disease endemic areas, the exact epidemiology, etiology and pathogenesis remain unknown, and the natural history is incompletely understood. [scopemed.org]
Part II: An epidemiologic, clinical, and pathologic study. Am Heart J 1968; 75: 107–124. Connor DH, Somers K, Hutt MS, et al. Endomyocardial fibrosis in Uganda (Davies’ disease). Part I: An epidemiologic, clinical, and pathologic study. [jrcd.eu]
An epidemiologic, clinical, and pathologic study. Am Heart J 74 : 687–709 3. Sliwa K et al. (2005) Epidemiology and etiology of cardiomyopathy in Africa. Circulation 112 : 3577–3583 4. [nature.com]
Pathophysiology
The pathophysiological hallmark of the disease is focal or diffuse endocardial thickening involving mainly the inflow, the apices, and the subvalvular region leading to valvular regurgitation, diastolic dysfunction and obliteration of the ventricular [ncbi.nlm.nih.gov]
The pathophysiology and clinical findings are reviewed, along with the various forms of medical and surgical therapy. The unique nature of this condition allowed a diagnosis prior to surgery in the second case. [mdedge.com]
Pathophysiology EMF involves both the right and left ventricle in 50% of cases. Forty percent of cases have solely the left ventricle involved, and in the remaining 10% of cases, the right ventricle is involved. [statpearls.com]
[…] including hypersensitivity myocarditis [14], parasitic infections [12,13], eosinophilic leukemia, sarcoma, carcinoma, and lymphoma [15], GM-CSF administration [16], and prolonged drug-induced eosinophilia Several infections have been implicated in the pathophysiology [slideshare.net]
Prevention
CONCLUSION: Short term prednisolone use was generally safe and did not prevent reaccumulation of ascites in this study population. TRIAL REGISTRATION NUMBER: ISRCTN63999319, 28/03/2013. [ncbi.nlm.nih.gov]
While RHD is unarguably the most preventable of all cardiac diseases, resulting from untreated or undertreated group A streptococcal infections, EMF’s etiology remains unclear. [journals.ac.za]