While a handful of reports have reported concurrent presentation, the authors present the first case of eyelid granuloma faciale with eosinophlilic angiocentric fibrosis. [ncbi.nlm.nih.gov]

• Dyspnea

  EAF can affect lower respiratory tracts with airway narrowing that can be characterized by dyspnea. We must consider narrowing of the lower respiratory tracts in patients with EAF complaining of unexplained persistent dyspnea. [ncbi.nlm.nih.gov]

  IgG4-related lung disease may be asymptomatic or has symptoms such as cough, hemoptysis, dyspnea, and chest pain 1, 2, 3. [synapse.koreamed.org]

  Unexplained persistent dyspnea in a young woman with eosinophilic angiocentric fibrosis. Respir Care. 2014;59(5):e72–6. doi: 10.4187/respcare.02645. 10. Valenzuela AA, Whitehead KJ, Brown I, Sullivan TJ. [link.springer.com]

  Unexplained persistent dyspnea in a young woman with eosinophilic angiocentric fibrosis. Respir Care. 2014;59(5):e72–6. PubMed View Article Google Scholar Paun S, Lund VJ, Gallimore A. [surgicalcasereports.springeropen.com]

  Some patients with IgG4-related lung disease experience cough, hemoptysis, dyspnea, pleural effusion, or chest discomfort (15, 56, 58). In others, however, the presence of lung disease is asymptomatic and discovered only incidentally upon imaging. [pancreapedia.org]

• Nasal Discharge

  All laboratory tests were unremarkable, except the nasal discharge eosinophil count that showed a conspicuous eosinophilia. [ncbi.nlm.nih.gov]

  Free PMC article Abstract A 58-year-old Caucasian male presented with left periorbital oedema extending to the nasal area for 1 year along with nasal discharge for 1 month. [pubmed.ncbi.nlm.nih.gov]

• Chronic Cough

  A 69-year-old female consulted our hospital following the detection of an abnormal chest shadow with chronic cough. [surgicalcasereports.springeropen.com]

• Stridor

  We report a case xc of 56-year-old lady referred to our institution with globus sensation, hoarseness, and mild stridor. Incidental subglottic mass was found at time of diagnostic microlaryngoscopy and biopsy confirmed subglottic EAF. [unboundmedicine.com]

• Periorbital Edema

  A 61-year-old man presented with a 6-week history of right periorbital edema and painless proptosis. Examination revealed a nonaxial proptosis, lateral globe displacement, and mild limitation in right eye adduction. [ncbi.nlm.nih.gov]

  Ophthalmic manifestations such as proptosis, periorbital edema, displacement of the eyeball and epiphora have been described more rarely. 2–5 A recent study has proposed that EAF could be part of the spectrum of IgG4-related diseases. 1 Our patient presented [elsevier.es]

• Multiple Pulmonary Nodules

  A CT scan of the thorax was performed to rule out granulomatosis with polyangiitis and showed multiple pulmonary nodules. [ncbi.nlm.nih.gov]

To date, no consensus has been reached on the optimal treatment of subglottic EAF. We recommend regular follow-up to detect early recurrence. [unboundmedicine.com]

Biopsies are necessary for diagnosis and treatment planning, although cures are usually of palliative effect. [ncbi.nlm.nih.gov]

Riwes, Brittany Pegouskie, Robert Mcgranahan, Monalisa Ghosh Tags: 498 Source Type: research Condition: Emergencies Intervention: Other: the difference of care management and prognosis, an early distinction of migraine aura based on imaging techniques [medworm.com]

PROGNOSIS AND TREATMENT CHARACTERIZATION Prognostic Factors Survival All alive but with disease at last follow-up Treatment Surgical excision for all patients Am J Clin Pathol 2001;115:243-248 Henry JB. [thedoctorsdoctor.com]

The patient's prognosis was excellent. We only found three previous reports, wherein rituximab was used to treat IHP and showed favorable results(2,3). REFERENCES 1. Zhao M, Geng T, Qiao L, Shi J, Xie J, Huang F, et al. [aboonline.org.br]

The etiology is unknown; however, severalfactors might play a role in the development of EAF. [ncbi.nlm.nih.gov]

All Andrology Astronomy Biochemistry Bioinformatics Biology Biophysics Biotechnology Botany Cardiology Cell Biology Chemistry Dermatology Ecology Epidemiology Evolutionary Biology General Genetics Genomics Geology Geriatrics Gynaecology Immunology Informatics [myjournals.org]

OUTLINE EPIDEMIOLOGY CHARACTERIZATION SYNONYMS EAF AGE RANGE-MEDIAN 28-64 years HISTOLOGICAL TYPES CHARACTERIZATION General Characteristic perivascular "onion-skin" fibrosis and a full spectrum of inflammatory cells, although eosinophils predominated [thedoctorsdoctor.com]

[ edit ] As recognition of IgG4-RD is relatively recent, there are limited studies on its epidemiology. [en.wikipedia.org]

The exact pathophysiology of EAF remains unclear. [ijpmonline.org]

The pathophysiology of KD may relate to a disturbance in the normal rate of production of eosinophils and IgE resulting in excessive elaboration of eosinophilotrophic cytokines such as interleukin 4 (Day 1995). KD is quite a rare condition. [mafiadoc.com]

The nomenclature system reinforces the concept that the same fundamental pathophysiologic processes are operative across organ systems, regardless of whether the role of IgG4 is primary or secondary. [pancreapedia.org]

[…] unknown about the behavior of the IgG4 molecule in vivo, the pathways through which this immunoglobulin participates in disease, and whether or not the role of IgG4 is primary or secondary. 20, 21, 22 In time, discoveries pertaining to the etiology and pathophysiology [nature.com]

Resecting of the involved tissues completely is essential for prevention of recurrence. [ncbi.nlm.nih.gov]

Resecting of the involved tissues completely is essential for prevention of recurrence. Authors User assignment Assign yourself or invite other person as author. It allow to create list of users contirbution. [infona.pl]

Author Robert A Schwartz, MD, MPH Professor and Head of Dermatology, Professor of Pathology, Pediatrics, Medicine, and Preventive Medicine and Community Health, Rutgers New Jersey Medical School; Visiting Professor, Rutgers University School of Public [emedicine.staging.medscape.com]