While a handful of reports have reported concurrent presentation, the authors present the first case of eyelid granuloma faciale with eosinophlilic angiocentric fibrosis. [ncbi.nlm.nih.gov]

• Soft Tissue Mass

  We report a 45-year-old man with progressive unilateral visual loss secondary to a retroorbital soft tissue mass with histological features consistent with EAF. [ncbi.nlm.nih.gov]

  CT often demonstrates a solid soft-tissue mass, (3) as occurred in our case. The progressive inflammatory process can result in fibrosis and partial airway obstruction. [thefreelibrary.com]

  The most common presentation was a submucosal or soft tissue mass in the upper respiratory tract (sinonasal cavity) and orbit, progressive nasal obstruction, and epiphora. [docslide.com.br]

  Axial ( A ) and coronal ( B ) CT images show an oval-shaped, well-defined, and isointense soft-tissue mass arising from left lateral nasal wall and extending into the nasal septum. [ajnr.org]

• Nasal Discharge

  All laboratory tests were unremarkable, except the nasal discharge eosinophil count that showed a conspicuous eosinophilia. [ncbi.nlm.nih.gov]

• Respiratory Distress

  Kim et al. reported a case of EAF that occurred in the bronchial lumen of a patient who presented with respiratory distress [ 5 ]. Similarly, in our case, chronic cough appeared as a local manifestation and disappeared after surgical treatment. [surgicalcasereports.springeropen.com]

• Periorbital Edema

  A 61-year-old man presented with a 6-week history of right periorbital edema and painless proptosis. Examination revealed a nonaxial proptosis, lateral globe displacement, and mild limitation in right eye adduction. [ncbi.nlm.nih.gov]

  Ophthalmic manifestations such as proptosis, periorbital edema, displacement of the eyeball and epiphora have been described more rarely. 2–5 A recent study has proposed that EAF could be part of the spectrum of IgG4-related diseases. 1 Our patient presented [elsevier.es]

• Facial Papule

  Onion skin fibrosis Differential diagnosis Granuloma faciale : inflammatory vascular reaction with facial papules, neutrophilic and eosinophilic infiltrate, vasculitis with fibrinoid material in vessel walls Advertisement [pathologyoutlines.com]

• Skin Plaque

  plaques or nodules on the face. [ijpmonline.org]

• Broad Nasal Bridge

  The physical examination showed that the patient had a broad nasal bridge, and for this reason, vasculitis (such as Wegener's and Churg-Strauss) were ruled out due to the absence of renal involvement and abnormalities in the chest radiograph. [elsevier.es]

• Fear

  Theethmoidal and intranasal components of the tumour were notincluded in our limited debulking surgery for fear of creatinga large deformity for a relatively benign condition. [myslide.es]

• Abulia

  Gornik Tags: Feature Article Source Type: research We report a case of severe neurotoxicity followed by significant depression and abulia. [medworm.com]

A combination of surgery and corticosteroids was the second-most-common treatment modality, used in 28.8% of cases. Of the 40 cases reporting patient outcomes, 100% of patients were alive at follow-up independent of treatment modality. [ncbi.nlm.nih.gov]

PROGNOSIS AND TREATMENT CHARACTERIZATION Prognostic Factors Survival All alive but with disease at last follow-up Treatment Surgical excision for all patients Am J Clin Pathol 2001;115:243-248 Henry JB. [thedoctorsdoctor.com]

Riwes, Brittany Pegouskie, Robert Mcgranahan, Monalisa Ghosh Tags: 498 Source Type: research Condition: Emergencies Intervention: Other: the difference of care management and prognosis, an early distinction of migraine aura based on imaging techniques [medworm.com]

The etiology is unknown; however, severalfactors might play a role in the development of EAF. [ncbi.nlm.nih.gov]

All Andrology Astronomy Biochemistry Bioinformatics Biology Biophysics Biotechnology Botany Cardiology Cell Biology Chemistry Dermatology Ecology Epidemiology Evolutionary Biology General Genetics Genomics Geology Geriatrics Gynaecology Immunology Informatics [myjournals.org]

OUTLINE EPIDEMIOLOGY CHARACTERIZATION SYNONYMS EAF AGE RANGE-MEDIAN 28-64 years HISTOLOGICAL TYPES CHARACTERIZATION General Characteristic perivascular "onion-skin" fibrosis and a full spectrum of inflammatory cells, although eosinophils predominated [thedoctorsdoctor.com]

[ edit ] As recognition of IgG4-RD is relatively recent, there are limited studies on its epidemiology. [en.wikipedia.org]

The exact pathophysiology of EAF remains unclear. [ijpmonline.org]

The pathophysiology of KD may relate to a disturbance in the normal rate of production of eosinophils and IgE resulting in excessive elaboration of eosinophilotrophic cytokines such as interleukin 4 (Day 1995). KD is quite a rare condition. [mafiadoc.com]

The nomenclature system reinforces the concept that the same fundamental pathophysiologic processes are operative across organ systems, regardless of whether the role of IgG4 is primary or secondary. [pancreapedia.org]

[…] unknown about the behavior of the IgG4 molecule in vivo, the pathways through which this immunoglobulin participates in disease, and whether or not the role of IgG4 is primary or secondary. 20, 21, 22 In time, discoveries pertaining to the etiology and pathophysiology [nature.com]

Resecting of the involved tissues completely is essential for prevention of recurrence. [ncbi.nlm.nih.gov]

Resecting of the involved tissues completely is essential for prevention of recurrence. Authors User assignment Assign yourself or invite other person as author. It allow to create list of users contirbution. [infona.pl]

Author Robert A Schwartz, MD, MPH Professor and Head of Dermatology, Professor of Pathology, Pediatrics, Medicine, and Preventive Medicine and Community Health, Rutgers New Jersey Medical School; Visiting Professor, Rutgers University School of Public [emedicine.staging.medscape.com]