Presentation
These observations and the presentation of our patient suggest that a histological diagnosis of ependymoblastoma of the spinal cord, with or without symptoms of intracranial tumor, should suggest that an intracranial primary lesion might be present. [ncbi.nlm.nih.gov]
Skin
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Subcutaneous Mass
We describe a case of congenital ependymoblastoma presenting as a subcutaneous mass in the sacrococcygeal area of a newborn male. [ncbi.nlm.nih.gov]
Psychiatrical
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Distractibility
Ependymoblastoma: dear, damned, distracting diagnosis, farewell!*. Brain Pathol 2010; 20 :133–9 [ PubMed ] [ Google Scholar ] [ncbi.nlm.nih.gov]
Neurologic
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Focal Neurological Deficit
There was no history of vomiting, other focal neurological deficit or trauma. On neurological examination, patient was alert, well oriented with no sensori-motor deficit. [ncbi.nlm.nih.gov]
Seizures and focal neurological deficits, with features of raised ICT are the symptoms at presentation. CT and MRI reveal a well differentiated, heterogenous, markedly enhancing hemispheric mass with varying degree of cystic or necrotic changes. [thamburaj.com]
Treatment
Prognosis of children with ependymoblastoma is poor, and data on clinical behavior and optimal treatment strategies are lacking, but sustained remissions have been achieved after multimodal treatment according to existing literature. [ncbi.nlm.nih.gov]
Children 3 years or younger: Standard treatment is usually surgery followed by chemotherapy. [secure.ssa.gov]
Prognosis
The prognosis seems to be far inferior to other embryonal CNS tumors, and known clinical and MRI characteristics of EBL are based on scattered case reports. [ncbi.nlm.nih.gov]
Prognosis of children with ependymoblastoma is poor, and data on clinical behavior and optimal treatment strategies are lacking, but sustained remissions have been achieved after multimodal treatment according to existing literature. [unboundmedicine.com]
Etiology
This lets people see incidence and survival patterns, evaluate diagnosis and treatment, facilitate etiologic studies, establish awareness of the disease, and ultimately, prevent brain tumors. [cern-foundation.org]
Etiology To theorize the "cell of origin" of ependymomas and related tumors, one needs only to look back through the stages of normal ependymal cell development. [emedicine.medscape.com]
Epidemiology
CONCLUSIONS: With this study, we add the largest case collection to the limited published database of MR imaging findings in ependymoblastoma, together with epidemiologic data. [ncbi.nlm.nih.gov]
Epidemiology Ependymoblastoma is a rare tumor that occurs in infants and young children in the first two years of life. Both sexes are affected equally. Localization Ependymoblastomas are large lesions that occur in the supratentorial compartment. [prod.wiki.cns.org]
[…] subclassification of embryonal tumors Rosettes are frequent and characteristic of embryonal tumors Ependymoblastoma lacks a neuropil-like matrix and ganglion cell elements Overexpression of LIN28A protein in C19MC altered embryonal tumors Poor prognosis Epidemiology [pathologyoutlines.com]
Pathophysiology
Mutism and pseudobulbar symptoms after resection of posterior fossa tumors in children: incidence and pathophysiology. Neurosurgery 37 (5): 885-93, 1995. [cancerinfo.tri-kobe.org]
Prevention
In order to prevent recurrence in future and good survival chances, a child may also undergo bone marrow or stem cell transplant. After the surgery, a medical team collects and freezes healthy stem cells of a child. [bookinghealth.com]
Prevention - Ependymoblastoma Not supplied. [checkorphan.org]
Please find comprehensive information on Ependymoma regarding definition, distribution, risk factors, causes, signs & symptoms, diagnosis, complications, treatment, prevention, prognosis, and additional useful information HERE. [dovemed.com]
Prevention There are no sure ways of preventing ependymomas. [knowcancer.com]
This lets people see incidence and survival patterns, evaluate diagnosis and treatment, facilitate etiologic studies, establish awareness of the disease, and ultimately, prevent brain tumors. [cern-foundation.org]