PMID: 12930305 Diagnosis Al-Thawabieh W, Lucky AW, Wong B, Motley WW J Pediatr Ophthalmol Strabismus 2018 Aug 29;55:e26-e29. doi: 10.3928/01913913-20180806-03. [ncbi.nlm.nih.gov]

Other ocular associations reported in EB include cataracts (11), cornea plana and sclerocornea (12), refractive errors, amblyopia, lacrimal duct obstruction, strabismus, lens subluxation, posterior vitreous detachment, and Graves’ disease. 2 This study [bjo.bmj.com]

Other ocular associations reported in EB include cataracts (11), cornea plana and sclerocornea (12), refractive errors, amblyopia, lacrimal duct obstruction, strabismus, lens subluxation, posterior vitreous detachment, and Graves’ disease. 2 This study [bjo.bmj.com]

The frequency of milia, mild atrophic scarring, focal plantar hyperkeratosis and nail dystrophy is intermediate between that of localized EBS and EBS-DM (see these terms), and extracutaneous findings, other than occasional intraoral blistering, are rare [orpha.net]

TY - JOUR T1 - Severe palmo-plantar hyperkeratosis in Koebner epidermolysis bullosa simplex. [unboundmedicine.com]

Because this goal is rarely achieved, e... more A 22-year-old Japanese woman with Koebner epidermolysis bullosa simplex presented with severe palmo-plantar hyperkeratosis. [scinapse.io]

Expression of a truncated keratin 5 may contribute to severe palmar-plantar hyperkeratosis in epidermolysis bullosa simplex patients. J. Invest. Derm. 116: 970-974, 2001. 19. Mulley, J. C.; Nicholls, C. M.; Propert, D. [genome.jp]

Keratolytics and softening agents for palmar plantar hyperkeratosis may prevent tissue thickening and cracking. [ncbi.nlm.nih.gov]

Hence, a minor injury, such as friction or rubbing, can separate the skin layers easily, resulting in painful skin tearing or blistering EB is not a preventable condition. However, blistering and complications can be prevented to a certain extent. [dovemed.com]

Clinical Synopsis: INHERITANCE: Autosomal dominant HEAD AND NECK: [Mouth]; Oral blistering SKIN, NAILS, HAIR: [Skin]; Blistering, generalized, recurrent (occurs after mild physical trauma); Hyperkeratosis of the palms and soles; Milia (less common); Lack [genome.jp]

Clinical Synopsis: INHERITANCE: Autosomal dominant HEAD AND NECK: [Mouth]; Oral blistering SKIN, NAILS, HAIR: [Skin]; Blistering, generalized, recurrent (occurs after mild physical trauma); Hyperkeratosis of the palms and soles; Milia (less common); Lack [genome.jp]

Exome sequencing in two cases suggested a novel non-synonymous variation, p.L325H, in the KRT5 gene. The present analysis also reports the first causative mutation of EBS Koebner type from India. [guardian.meragenome.com]

The generalized Koebner form and the localized Weber-Cockayne type were believed to be allelic. {11:Gedde-Dahl (1981)} recognized at least 16 varieties of epidermolysis bullosa and suggested that dominant EB simplex can be clinically and genetically divided [diseaseinfosearch.org]

Gedde-Dahl (1981) recognized at least 16 varieties of epidermolysis bullosa and suggested that dominant EB simplex can be clinically and genetically divided into at least 4 types: the generalized Koebner type, the localized Weber-Cockayne type, the mild [malacards.org]